Sfoglia per Autore
Arsenite-induced mitochondrial superoxide formation: time and concentration requirements for the effects of the metalloid on the endoplasmic reticulum and mitochondria
2020 Guidarelli, Andrea; Cerioni, Liana; Fiorani, Mara; Catalani, Alessia; Cantoni, Orazio
Calcium signals between the ryanodine receptor- and mitochondria critically regulate the effects of arsenite on mitochondrial superoxide formation and on the ensuing survival vs apoptotic signaling
2019 Guidarelli, Andrea; Fiorani, Mara; Cerioni, Liana; Cantoni, Orazio
The compartmentalised nature of the mechanisms governing superoxide formation and scavenging in cells exposed to arsenite
2019 Guidarelli, Andrea; Fiorani, Mara; Cerioni, Liana; Cantoni, Orazio
Prostaglandin E2 Signals Through E Prostanoid Receptor 2 to Inhibit Mitochondrial Superoxide Formation and the Ensuing Downstream Cytotoxic and Genotoxic Effects Induced by Arsenite
2019 Cerioni, Liana; Guidarelli, Andrea; Fiorani, Mara; Cantoni, Orazio
Melatonin protects hippocampal HT22 cells from the effects of serum deprivation specifically targeting mitochondria
2018 Cesarini, E.; Cerioni, L.; Canonico, B.; Di Sario, G.; Guidarelli, A.; Lattanzi, D.; Savelli, D.; Guescini, M.; Nasoni, M. G.; Bigini, N.; Cuppini, R.; Stocchi, V.; Ambrogini, P.; Papa, S; Luchetti, F.
The dual role of mitochondrial superoxide in arsenite toxicity: Signaling at the boundary between apoptotic commitment and cytoprotection
2018 Fiorani, Mara; Guidarelli, Andrea; Capellacci, Valentina; Cerioni, Liana; Crinelli, Rita; Cantoni, Orazio
Intramitochondrial Ascorbic Acid Enhances the Formation of Mitochondrial Superoxide Induced by Peroxynitrite via a Ca(2+)-Independent Mechanism
2017 Guidarelli, Andrea; Cerioni, Liana; Fiorani, Mara; Cantoni, Orazio
Arsenite induces DNA damage via mitochondrial ROS and induction of mitochondrial permeability transition
2017 Guidarelli, Andrea; Fiorani, Mara; Cerioni, Liana; Scotti, Maddalena; Cantoni, Orazio
The study of the mechanism of arsenite toxicity in respiration-deficient cells reveals that NADPH oxidase-derived superoxide promotes the same downstream events mediated by mitochondrial superoxide in respiration-proficient cells
2016 Guidarelli, Andrea; Fiorani, Mara; Carloni, Silvia; Cerioni, Liana; Balduini, Walter; Cantoni, Orazio
Intracellular dehydroascorbic acid inhibits SVCT2-dependent transport of ascorbic acid in mitochondria
2015 Fiorani, Mara; Azzolini, Catia; Guidarelli, Andrea; Cerioni, Liana; Scotti, Maddalena; Cantoni, Orazio
The mitochondrial transporter of ascorbic acid functions with high affinity in the presence of low millimolar concentrations of sodium and in the absence of calcium and magnesium
2015 Fiorani, Mara; Catia, Azzolini; Cerioni, Liana; Scotti, Maddalena; Guidarelli, Andrea; Ciacci, Caterina; Cantoni, Orazio
U937 cell apoptosis induced by arsenite is prevented by low concentrations of mitochondrial ascorbic acid with hardly any effect mediated by the cytosolic fraction of the vitamin
2015 Guidarelli, Andrea; Fiorani, Mara; Catia, Azzolini; Cerioni, Liana; Scotti, Maddalena; Cantoni, Orazio
A novel biological role of dehydroascorbic acid: Inhibition of Na+-dependent transport of ascorbic acid.
2014 Fiorani, Mara; Azzolini, Catia; Guidarelli, Andrea; Cerioni, Liana; Cantoni, Orazio
Mitochondrial ascorbic acid is responsible for enhanced susceptibility of U937 cells to the toxic effects of peroxynitrite
2014 Guidarelli, Andrea; Cerioni, Liana; Fiorani, Mara; Azzolini, Catia; Cantoni, Orazio
Sodium-dependent transport of ascorbic acid in U937 cell mitochondria.
2013 Azzolini, Catia; Fiorani, Mara; Cerioni, Liana; Guidarelli, Andrea; Cantoni, Orazio
Superoxide dictates the mode of U937 cell ascorbic acid uptake and prevents the enhancing effects of the vitamin to otherwise non-toxic levels of reactive oxygen/nitrogen species
2013 Fiorani, Mara; Azzolini, Catia; Cerioni, Liana; Guidarelli, Andrea; Cantoni, Orazio
A moderate decline in U937 cell GSH levels triggers PI3 kinase/Akt-dependent Bad phosphorylation, thereby preventing an otherwise prompt apoptotic response
2012 Cerioni, Liana; Fiorani, Mara; Azzolini, Catia; Cantoni, Orazio
Assessing bad sub-cellular localization under conditions associated with prevention or promotion of mitochondrial permeability transition-dependent toxicity.
2010 Cerioni, Liana; Cantoni, Orazio
Differentiation-associated loss of ryanodine receptors: a strategy adopted by monocytes/macrophages to prevent the DNA single-strand breakage induced by peroxynitrite.
2009 Guidarelli, Andrea; Cerioni, Liana; Fiorani, Mara; Cantoni, Orazio
Prostaglandin E2 signals monocyte/macrophage survival to peroxynitrite via protein kinase A converging in bad phosphorylation with the protein kinase C alpha-dependent pathway driven by 5-hydroxyeicosatetraenoic acid.
2008 Tommasini, I; Cerioni, Liana; Palomba, Letizia; Cantoni, Orazio
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