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Mostrati risultati da 1 a 20 di 68
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Investigating the Unbinding of Muscarinic Antagonists from the Muscarinic 3 Receptor 1-gen-2023 Buigues, Pedro J; Gehrke, Sascha; Badaoui, Magd; Dudas, Balint; Mandana, Gaurav; Qi, Tianyun; Bottegoni, Giovanni; Rosta, Edina
Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties 1-gen-2023 Basagni, Filippo; Ortega, Jose A; Bertozzi, Sine M; Armirotti, Andrea; Summa, Maria; Bertorelli, Rosalia; Bartolini, Manuela; Mellor, Ian R; Bedeschi, Martina; Bottegoni, Giovanni; Lembo, Vittorio; Minarini, Anna; Cavalli, Andrea; Rosini, Michela
The multitarget FAAH inhibitor/D3 partial agonist ARN15381 decreases nicotine self-administration in male rats 1-gen-2022 Lunerti, Veronica; Li, Hongwu; Benvenuti, Federica; Shen, Qianwei; Domi, Ana; Soverchia, Laura; Concetta Di Martino, Rita Maria; Bottegoni, Giovanni; Haass-Koffler, Carolina L; Cannella, Nazzareno
Dopamine D3 receptor ligands: a patent review (2014-2020) 1-gen-2022 Di Martino, Rita Maria Concetta; Cavalli, Andrea; Bottegoni, Giovanni
Discovery and SAR Evolution of Pyrazole Azabicyclo[3.2.1]octane Sulfonamides as a Novel Class of Non-Covalent N-Acylethanolamine-Hydrolyzing Acid Amidase (NAAA) Inhibitors for Oral Administration 1-gen-2021 Di Fruscia, Paolo; Carbone, Anna; Bottegoni, Giovanni; Berti, Francesco; Giacomina, Francesca; Ponzano, Stefano; Pagliuca, Chiara; Fiasella, Annalisa; Pizzirani, Daniela; Antonio Ortega, Jose; Nuzzi, Andrea; Tarozzo, Glauco; Mengatto, Luisa; Giampà, Roberta; Penna, Ilaria; Russo, Debora; Romeo, Elisa; Summa, Maria; Bertorelli, Rosalia; Armirotti, Andrea; Mandrup Bertozzi, Sine; Reggiani, Angelo; Bandiera, Tiziano; Fabio Bertozzi, And
Inflammation causes remodeling of mitochondrial cytochrome c oxidase mediated by the bifunctional gene C15orf48 1-gen-2021 Clayton, Sally A; Daley, Kalbinder K; Macdonald, Lucy; Fernandez-Vizarra, Erika; Bottegoni, Giovanni; O'Neil, John D; Major, Triin; Griffin, Daniel; Zhuang, Qinqin; Adewoye, Adeolu B; Woolcock, Kieran; Jones, Simon W; Goodyear, Carl; Elmesmari, Aziza; Filer, Andrew; Tennant, Daniel A; Alivernini, Stefano; Buckley, Christopher D; Pitceathly, Robert D S; Kurowska-Stolarska, Mariola; Clark, Andrew R
Multi-target dopamine D3 receptor modulators: Actionable knowledge for drug design from molecular dynamics and machine learning 1-gen-2020 Ferraro, Mariarosaria; Decherchi, Sergio; De Simone, Alessio; Recanatini, Maurizio; Cavalli, Andrea; Bottegoni, Giovanni
Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation 1-gen-2020 Di Martino, Rita Maria Concetta; Bottegoni, Giovanni; Seghetti, Francesca; Russo, Debora; Penna, Ilaria; De Simone, Alessio; Ottonello, Giuliana; Mandrup Bertozzi, Sine; Armirotti, Andrea; Bandiera, Tiziano; Belluti, Federica; Cavalli, Andrea
A Triazolotriazine-Based Dual GSK-3β/CK-1δ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition 1-gen-2019 Redenti, Sara; Marcovich, Irene; De Vita, Teresa; Pérez, Concepción; De Zorzi, Rita; Demitri, Nicola; Perez, Daniel I.; Bottegoni, Giovanni; Bisignano, Paola; Bissaro, Maicol; Moro, Stefano; Martinez, Ana; Storici, Paola; Spalluto, Giampiero; Cavalli, Andrea; Federico, Stephanie
BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease 1-gen-2018 Prati, F; Bottegoni, G; Bolognesi, Ml; Cavalli, A
Structure of the complement C5a receptor bound to the extra-helical antagonist NDT9513727 1-gen-2018 Robertson, N; Rappas, M; Dore, As; Brown, J; Bottegoni, G; Koglin, M; Cansfield, J; Jazayeri, A; Cooke, Rm; Marshall, Fh
BiKi Life Sciences: A New Suite for Molecular Dynamics and Related Methods in Drug Discovery 1-gen-2018 Decherchi, S; Bottegoni, G; Spitaleri, A; Rocchia, W; Cavalli, A
Multitarget drug design strategy in Alzheimer's disease: focus on cholinergic transmission and amyloid-beta aggregation 1-gen-2017 Simoni, E; Bartolini, M; Abu, If; Blockley, A; Gotti, C; Bottegoni, G; Caporaso, R; Bergamini, C; Andrisano, V; Cavalli, A; Mellor, Ir; Minarini, A; Rosini, M
Design, Synthesis, Structure-Activity Relationship Studies, and Three-Dimensional Quantitative Structure Activity Relationship (3D-QSAR) Modeling of a Series of O-Biphenyl Carbamates as Dual Modulators of Dopamine D3 Receptor and Fatty Acid Amide Hydrolase 1-gen-2017 De Simone, A; Russo, D; Ruda, Gf; Micoli, A; Ferraro, M; Di Martino, Rmc; Ottonello, G; Summa, M; Armirotti, A; Bandiera, T; Cavalli, A; Bottegoni, G
Pyrazole-Based Acid Ceramidase Inhibitors: Design, Synthesis, and Structure-Activity Relationships 1-gen-2016 Diamanti, E; Bottegoni, G; Goldoni, L; Realini, N; Pagliuca, C; Bertozzi, F; Piomelli, D; Pizzirani, D
Role of Molecular Dynamics and Related Methods in Drug Discovery 1-gen-2016 DE VIVO, Marco; Masetti, Matteo; Bottegoni, Giovanni; Cavalli, Andrea
Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3β Inhibitors 1-gen-2016 DI MARTINO, RITA MARIA CONCETTA; DE SIMONE, Angela; Andrisano, Vincenza; Bisignano, Paola; Bisi, Alessandra; Gobbi, Silvia; Rampa, Angela; Fato, Romana; Bergamini, Christian; Perez, Daniel I.; Martinez, Ana; Bottegoni, Giovanni; Cavalli, Andrea; Belluti, Federica
Mapping cholesterol interaction sites on serotonin transporter through coarse-grained molecular dynamics 1-gen-2016 Ferraro, Mariarosaria; Masetti, Matteo; Recanatini, Maurizio; Cavalli, Andrea; Bottegoni, Giovanni
Development and Application of a Virtual Screening Protocol for the Identification of Multitarget Fragments 1-gen-2016 Bottegoni, G; Veronesi, M; Bisignano, P; Kacker, P; Favia, Ad; Cavalli, A
Aryl and heteroaryl N-[4-[4-(2,3-substituted-phenyl)piperazine-1-yl]alkyl] carbamates with improved physico-chemical properties as dual modulators of dopamine D3 receptor and fatty acid amide hydrolase 1-gen-2016 Micoli, A; De Simone, A; Russo, D; Ottonello, G; Colombano, G; Ruda, Gf; Bandiera, T; Cavalli, A; Bottegoni, G
Mostrati risultati da 1 a 20 di 68
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