Sfoglia per Autore
N-Acylethanolamine Acid Amidase (NAAA): Structure, Function, and Inhibition
2020 Piomelli, Daniele; Scalvini, Laura; Fotio, Yannick; Lodola, Alessio; Spadoni, Gilberto; Tarzia, Giorgio; Mor, Marco
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase
2016 Piomelli, D; Tarzia, Giorgio; Mor, M; Duranti, Andrea; Tontini, Andrea
Potent, Metabolically Stable 2-Alkyl-8-(2H-1,2,3-triazol-2-yl)-9H-adenines as Adenosine A2A Receptor Ligands
2015 Pace, Silvia; Brogin, Giandomenico; Stasi, Maria Antonietta; Riccioni, Teresa; Borsini, Franco; Capocasa, Francesca; Manera, Francesco; Tallarico, Carlo; Grossi, Pietro; Vacondio, Federica; Bassi, Michele; Bartoccini, Francesca; Lucarini, Simone; Piersanti, Giovanni; Tarzia, Giorgio; Cabri, Walter; Minetti, Patrizia
Towards the development of 5-HT7 ligands combining serotonin-like and arylpiperazine moieties
2014 Spadoni, Gilberto; Bedini, Annalida; Bartolucci, Silvia; Pala, D.; Mor, M.; Riccioni, T.; Borsini, F.; Cabri, W.; Celona, D.; Marzi, M.; Tarzia, Giorgio; Rivara, S.; Minetti, P.
Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain
2014 MORENO SANZ, G; Barrera, B; Armirotti, A; MANDRUP BERTOZZI, S; Prieto, Jg; Scarpelli, R; Duranti, Andrea; Tarzia, Giorgio; Bandiera, T; Merino, G; Piomelli, D.
Melatonin, non-selective MT1/MT2 and selective MT2 receptor agonists: differential effects on the 24-hr vigilance states
2014 Ochoa Sanchez, R.; Comai, S.; Spadoni, Gilberto; Bedini, Annalida; Tarzia, Giorgio; Gobbi, G.
O-Biphenyl-3-yl Carbamates as Peripheral FAAH Inhibitors: Synthesis and Structure–Activity (SAR) Relationship Studies
2013 Mestichelli, Paola; MORENO SANZ, G; Duranti, Andrea; Sanchini, Silvano; Tontini, Andrea; Lodola, A; Mor, M; Bandiera, T; Piomelli, D; Tarzia, Giorgio
Sintesi e studi di relazione struttura–attività/selettività su O-bifenil-3-ilcarbammati disostituiti quali inibitori periferici dell’enzima FAAH
2013 Mestichelli, Paola; MORENO SANZ, G; Duranti, Andrea; Sanchini, Silvano; Tontini, Andrea; Lodola, A; Mor, M; Bandiera, T; Piomelli, D; Tarzia, Giorgio
Synthesis and Structure–Activity Relationship (SAR) of 2-Methyl-4-oxo-3-oxetanyl Carbamic Acid Esters, a Class of Potent N-Acylethanolamine Acid Amidase (NAAA) Inhibitors
2013 Ponzano, S; Bertozzi, F; Mengatto, L; Dionisi, M; Armirotti, A; Romeo, E; Berteotti, A; Fiorelli, C; Tarozzo, G; Reggiani, A; Duranti, Andrea; Tarzia, Giorgio; Mor, M; Cavalli, A; Piomelli, D; Bandiera, T.
Synthesis of (E)-8-(3-Chlorostyryl)caffeine Analogues Leading to 9-Deazaxanthine Derivatives as Dual A2AAntagonists/MAO-B Inhibitors
2013 Silvia, Rivara; Piersanti, Giovanni; Bartoccini, Francesca; Diamantini, Giuseppe; Daniele, Pala; Teresa, Riccioni; Maria Antonietta, Stasi; Walter, Cabri; Franco, Borsini; Marco, Mor; Tarzia, Giorgio; Patrizia, Minetti
Antinoceptive Effects of the N-Acylethanolamine Acid Amidase Inhibitor ARN077 in Rodent Pain Models
2013 Sasso, O; MORENO SANZ, G; Martucci, C; Realini, N; Dionisi, M; Mengatto, L; Duranti, Andrea; Tarozzo, G; Tarzia, Giorgio; Mor, M; Bertorelli, R; Reggiani, A; Piomelli, D.
Synthesis and Structure–Activity Relationship Studies of O-Biphenyl-3-yl Carbamates as Peripherally Restricted Fatty Acid Amide Hydrolase Inhibitors
2013 MORENO SANZ, G; Duranti, Andrea; Melzig, L; Fiorelli, C; Ruda, Gf; Colombano, G; Mestichelli, Paola; Sanchini, Silvano; Tontini, Andrea; Mor, M; Bandiera, T; Scarpelli, R; Tarzia, Giorgio; Piomelli, D.
Synthesis and Biological Evaluation of Metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), A Potent Antagonist of the A2AAdenosine Receptor for the Treatment of Parkinson’s Disease
2013 Piersanti, Giovanni; Bartoccini, Francesca; Lucarini, Simone; Walter, Cabri; Maria Antonietta, Stasi; Teresa, Riccioni; Franco, Borsini; Tarzia, Giorgio; Patrizia, Minetti
Correlation between energetics of collisionally activated decomposition, interaction energy and biological stability of some N-Acylethanolamine acid amidase inhibitors
2012 Isak, I; Duranti, Andrea; Mor, M; Pomelli, D; Tarzia, Giorgio; Traldi, P.
Relationships Between Mass Spectrometry and Biological Stability of Some N-Acylethanolamine Acid Amidase Inhibitors
2012 Isak, I; Duranti, Andrea; Mor, M; Piomelli, D; Tarzia, Giorgio; Traldi, P.
Structure–Activity and Structure–Property Relationships of N-(2-Oxo-3-Oxetanyl)carbamic Acid Esters as N-Acylethanolamine-hydrolyzing Acid Amidase (NAAA) Inhibitors
2012 Lodola, A; Vacondio, F; Rivara, S; Silva, C; Duranti, Andrea; Tontini, Andrea; Tarzia, Giorgio; Piomelli, D; Mor, M.
Structure Activity Relationships (SARs) and mechanism of action of a potent class of N-acylethanolamine acid amidase (NAAA) inhibitors
2012 Ponzano, S; Armirotti, A; Bertozzi, F; Romeo, E; Mengatto, L; Dionisi, M; Karacsonyi, C; Garau, G; Berteotti, A; Fiorelli, C; Tarozzo, G; Reggiani, A; Duranti, Andrea; Tarzia, Giorgio; Mor, M; Cavalli, A; Piomelli, D; Bandiera, T.
Peripherally Restricted FAAH Inhibitors
2012 Piomelli, D; Clapper, Jr; MORENO SANZ, G; Duranti, Andrea; Tontini, Andrea; Mor, M; Tarzia, Giorgio
N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis, Structure–Activity and Structure–Property Relationships
2012 Duranti, Andrea; Tontini, Andrea; Antonietti, Francesca; Vacondio, F; Fioni, A; Silva, C; Lodola, A; Rivara, S; Solorzano, C; Piomelli, D; Tarzia, Giorgio; Mor, M.
Divergent synthesis of novel 9-deazaxanthine derivatives via late-stage cross-coupling reactions
2012 Bartoccini, Francesca; Piersanti, Giovanni; Marco, Mor; Tarzia, Giorgio; Patrizia, Minetti; Walter, Cabri
Titolo | Data di pubblicazione | Autore(i) | File |
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N-Acylethanolamine Acid Amidase (NAAA): Structure, Function, and Inhibition | 1-gen-2020 | Piomelli, Daniele; Scalvini, Laura; Fotio, Yannick; Lodola, Alessio; Spadoni, Gilberto; Tarzia, Giorgio; Mor, Marco | |
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase | 1-gen-2016 | Piomelli, D; Tarzia, Giorgio; Mor, M; Duranti, Andrea; Tontini, Andrea | |
Potent, Metabolically Stable 2-Alkyl-8-(2H-1,2,3-triazol-2-yl)-9H-adenines as Adenosine A2A Receptor Ligands | 1-gen-2015 | Pace, Silvia; Brogin, Giandomenico; Stasi, Maria Antonietta; Riccioni, Teresa; Borsini, Franco; Capocasa, Francesca; Manera, Francesco; Tallarico, Carlo; Grossi, Pietro; Vacondio, Federica; Bassi, Michele; Bartoccini, Francesca; Lucarini, Simone; Piersanti, Giovanni; Tarzia, Giorgio; Cabri, Walter; Minetti, Patrizia | |
Towards the development of 5-HT7 ligands combining serotonin-like and arylpiperazine moieties | 1-gen-2014 | Spadoni, Gilberto; Bedini, Annalida; Bartolucci, Silvia; Pala, D.; Mor, M.; Riccioni, T.; Borsini, F.; Cabri, W.; Celona, D.; Marzi, M.; Tarzia, Giorgio; Rivara, S.; Minetti, P. | |
Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain | 1-gen-2014 | MORENO SANZ, G; Barrera, B; Armirotti, A; MANDRUP BERTOZZI, S; Prieto, Jg; Scarpelli, R; Duranti, Andrea; Tarzia, Giorgio; Bandiera, T; Merino, G; Piomelli, D. | |
Melatonin, non-selective MT1/MT2 and selective MT2 receptor agonists: differential effects on the 24-hr vigilance states | 1-gen-2014 | Ochoa Sanchez, R.; Comai, S.; Spadoni, Gilberto; Bedini, Annalida; Tarzia, Giorgio; Gobbi, G. | |
O-Biphenyl-3-yl Carbamates as Peripheral FAAH Inhibitors: Synthesis and Structure–Activity (SAR) Relationship Studies | 1-gen-2013 | Mestichelli, Paola; MORENO SANZ, G; Duranti, Andrea; Sanchini, Silvano; Tontini, Andrea; Lodola, A; Mor, M; Bandiera, T; Piomelli, D; Tarzia, Giorgio | |
Sintesi e studi di relazione struttura–attività/selettività su O-bifenil-3-ilcarbammati disostituiti quali inibitori periferici dell’enzima FAAH | 1-gen-2013 | Mestichelli, Paola; MORENO SANZ, G; Duranti, Andrea; Sanchini, Silvano; Tontini, Andrea; Lodola, A; Mor, M; Bandiera, T; Piomelli, D; Tarzia, Giorgio | |
Synthesis and Structure–Activity Relationship (SAR) of 2-Methyl-4-oxo-3-oxetanyl Carbamic Acid Esters, a Class of Potent N-Acylethanolamine Acid Amidase (NAAA) Inhibitors | 1-gen-2013 | Ponzano, S; Bertozzi, F; Mengatto, L; Dionisi, M; Armirotti, A; Romeo, E; Berteotti, A; Fiorelli, C; Tarozzo, G; Reggiani, A; Duranti, Andrea; Tarzia, Giorgio; Mor, M; Cavalli, A; Piomelli, D; Bandiera, T. | |
Synthesis of (E)-8-(3-Chlorostyryl)caffeine Analogues Leading to 9-Deazaxanthine Derivatives as Dual A2AAntagonists/MAO-B Inhibitors | 1-gen-2013 | Silvia, Rivara; Piersanti, Giovanni; Bartoccini, Francesca; Diamantini, Giuseppe; Daniele, Pala; Teresa, Riccioni; Maria Antonietta, Stasi; Walter, Cabri; Franco, Borsini; Marco, Mor; Tarzia, Giorgio; Patrizia, Minetti | |
Antinoceptive Effects of the N-Acylethanolamine Acid Amidase Inhibitor ARN077 in Rodent Pain Models | 1-gen-2013 | Sasso, O; MORENO SANZ, G; Martucci, C; Realini, N; Dionisi, M; Mengatto, L; Duranti, Andrea; Tarozzo, G; Tarzia, Giorgio; Mor, M; Bertorelli, R; Reggiani, A; Piomelli, D. | |
Synthesis and Structure–Activity Relationship Studies of O-Biphenyl-3-yl Carbamates as Peripherally Restricted Fatty Acid Amide Hydrolase Inhibitors | 1-gen-2013 | MORENO SANZ, G; Duranti, Andrea; Melzig, L; Fiorelli, C; Ruda, Gf; Colombano, G; Mestichelli, Paola; Sanchini, Silvano; Tontini, Andrea; Mor, M; Bandiera, T; Scarpelli, R; Tarzia, Giorgio; Piomelli, D. | |
Synthesis and Biological Evaluation of Metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), A Potent Antagonist of the A2AAdenosine Receptor for the Treatment of Parkinson’s Disease | 1-gen-2013 | Piersanti, Giovanni; Bartoccini, Francesca; Lucarini, Simone; Walter, Cabri; Maria Antonietta, Stasi; Teresa, Riccioni; Franco, Borsini; Tarzia, Giorgio; Patrizia, Minetti | |
Correlation between energetics of collisionally activated decomposition, interaction energy and biological stability of some N-Acylethanolamine acid amidase inhibitors | 1-gen-2012 | Isak, I; Duranti, Andrea; Mor, M; Pomelli, D; Tarzia, Giorgio; Traldi, P. | |
Relationships Between Mass Spectrometry and Biological Stability of Some N-Acylethanolamine Acid Amidase Inhibitors | 1-gen-2012 | Isak, I; Duranti, Andrea; Mor, M; Piomelli, D; Tarzia, Giorgio; Traldi, P. | |
Structure–Activity and Structure–Property Relationships of N-(2-Oxo-3-Oxetanyl)carbamic Acid Esters as N-Acylethanolamine-hydrolyzing Acid Amidase (NAAA) Inhibitors | 1-gen-2012 | Lodola, A; Vacondio, F; Rivara, S; Silva, C; Duranti, Andrea; Tontini, Andrea; Tarzia, Giorgio; Piomelli, D; Mor, M. | |
Structure Activity Relationships (SARs) and mechanism of action of a potent class of N-acylethanolamine acid amidase (NAAA) inhibitors | 1-gen-2012 | Ponzano, S; Armirotti, A; Bertozzi, F; Romeo, E; Mengatto, L; Dionisi, M; Karacsonyi, C; Garau, G; Berteotti, A; Fiorelli, C; Tarozzo, G; Reggiani, A; Duranti, Andrea; Tarzia, Giorgio; Mor, M; Cavalli, A; Piomelli, D; Bandiera, T. | |
Peripherally Restricted FAAH Inhibitors | 1-gen-2012 | Piomelli, D; Clapper, Jr; MORENO SANZ, G; Duranti, Andrea; Tontini, Andrea; Mor, M; Tarzia, Giorgio | |
N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis, Structure–Activity and Structure–Property Relationships | 1-gen-2012 | Duranti, Andrea; Tontini, Andrea; Antonietti, Francesca; Vacondio, F; Fioni, A; Silva, C; Lodola, A; Rivara, S; Solorzano, C; Piomelli, D; Tarzia, Giorgio; Mor, M. | |
Divergent synthesis of novel 9-deazaxanthine derivatives via late-stage cross-coupling reactions | 1-gen-2012 | Bartoccini, Francesca; Piersanti, Giovanni; Marco, Mor; Tarzia, Giorgio; Patrizia, Minetti; Walter, Cabri |
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