Sfoglia per Autore
Differentiation-associated loss of ryanodine receptors: a strategy adopted by monocytes/macrophages to prevent the DNA single-strand breakage induced by peroxynitrite.
2009 Guidarelli, Andrea; Cerioni, Liana; Fiorani, Mara; Cantoni, Orazio
Peroxynitrite damages U937 cell DNA via the intermediate formation of mitochondrial oxidants.
2008 Cantoni, Orazio; Guidarelli, Andrea
Susceptibility of rat astrocytes to DNA strand scission induced by activation of NADPH oxidase and collateral resistance to the effects of peroxynitrite.
2008 Guidarelli, Andrea; Palomba, Letizia; Fiorani, Mara; Cantoni, Orazio
Indirect Mechanisms of DNA Strand Scission by Peroxynitrite
2008 Cantoni, Orazio; Guidarelli, Andrea
Inhibition of complex III promotes loss of Ca2+ dependence for mitochondrial superoxide formation and permeability transition evoked by peroxynitrite.
2007 Guidarelli, Andrea; Cerioni, Liana; Cantoni, Orazio
Phenolic-rich juice prevents DNA single-strand breakage and cytotoxicity caused by tert-butylhydroperoxide in U937 cells: the role of iron chelation.
2007 GARCIA ALONSO, Fj; Guidarelli, Andrea; Periago, Mj
Reduced mitochondrial formation of H(2)O(2) is responsible for resistance of dimethyl sufoxide differentiated U937 cells to peroxynitrite
2006 Guidarelli, Andrea; Fiorani, Mara; Tommasini, I; Cerioni, Liana; Cantoni, Orazio
5-Hydroxyeicosatetraenoic acid is a key intermediate of the arachidonate-dependent protective signaling in monocytes/macrophages exposed to peroxynitrite.
2006 Tommasini, I; Guidarelli, Andrea; Palomba, Letizia; Cerioni, Liana; Cantoni, Orazio
Peroxynitrite mobilizes calcium ions from ryanodine-sensitive stores, a process associated with the mitochondrial accumulation of the cation and the enforced formation of species mediating cleavage of genomic DNA.
2006 Guidarelli, Andrea; Sciorati, C; Clementi, E; Cantoni, Orazio
ERK1/2-dependent regulation of U937 cell survival after exposure to peroxynitrite.
2005 Tommasini, I; Cerioni, Liana; Guidarelli, Andrea; Cantoni, Orazio
U937 cell necrosis mediated by peroxynitrite is not caused by depletion of ATP and is prevented by arachidonate via an ATP-dependent mechanism.
2005 Cantoni, Orazio; Guidarelli, Andrea; Palomba, Letizia; Fiorani, Mara
Survival pathways triggered by peroxynitrite in cells belonging to the monocyte/macrophage lineage
2005 Cantoni, Orazio; Tommasini, I; Cerioni, Liana; Palomba, Letizia; Carloni, E; Guidarelli, Andrea
A downstream role for protein kinase C alpha in the cytosolic phospholipase A2-dependent protective signalling mediated by peroxynitrite in U937 cells.
2005 Guidarelli, Andrea; Cerioni, Liana; Tommasini, I; Brune, B; Cantoni, Orazio
Role of Bcl-2 in the arachidonate-mediated survival signaling preventing mitochondrial permeability transition-dependent U937 cell necrosis induced by peroxynitrite
2005 Guidarelli, Andrea; Cerioni, Liana; Tommasini, I; Fiorani, Mara; Brune, B; Cantoni, Orazio
Enhancing effects of intracellular ascorbic acid on peroxynitrite-induced U937 cell death are mediated by mitochondrial events resulting in enhanced sensitivity to peroxynitrite-dependent inhibition of complex III and formation of hydrogen peroxide.
2004 Guidarelli, Andrea; Fiorani, Mara; Cantoni, Orazio
The arachidonate-dependent cytoprotective signaling evoked by peroxynitrite is a general response of the monocyte/macrophage lineage
2004 Tommasini, I; Guidarelli, Andrea; Cerioni, Liana; Cantoni, Orazio
Hydrogen peroxide generated at the level of mitochondria in response to peroxynitrite promotes U937 cell death via inhibition of the cytoprotective signalling mediated by cytosolic phospholipase A2
2004 Tommasini, I.; Sestili, Piero; Guidarelli, Andrea; Cantoni, Orazio
NON-TOXIC CONCENTRATIONS OF PEROXYNITRITE COMMIT U937 CELLS TO MITOCHONDRIAL PERMEABILITY TRANSITION-DEPENDENT NECROSIS THAT IS HOWEVER PREVENTED BY ENDOGENOUS ARACHIDONIC ACID
2004 Tommasini, I; Guidarelli, Andrea; Cantoni, Orazio
Peroxynitrite stimulates the activity of cytosolic phospholipase A2 in U937 cells: the extent of arachidonic acid formation regulates the balance between cell survival or death.
2002 Tommasini, I.; Sestili, Piero; Guidarelli, Andrea; Cantoni, Orazio
Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells
2002 Brigotti, M.; Alfieri, R.; Sestili, Piero; Bonelli, M.; Petronini, P. G.; Guidarelli, Andrea; Barbieri, L.; Stirpe, F.; Sperti, S.
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