SPINA, ANDREA
SPINA, ANDREA
Dipartimento di Scienze Biomolecolari (DISB)
Arsenite enhances ERO1α expression via ryanodine receptor dependent and independent mechanisms
2023 Guidarelli, Andrea; Spina, Andrea; Fiorani, Mara; Zito, Ester; Cantoni, Orazio
Crosstalk between ERO1α and ryanodine receptor in arsenite-dependent mitochondrial ROS formation
2022 Spina, Andrea; Guidarelli, Andrea; Fiorani, Mara; Varone, Ersilia; Catalani, Alessia; Zito, Ester; Cantoni, Orazio
ERO1α primes the ryanodine receptor to respond to arsenite with concentration dependent Ca2+ release sequentially triggering two different mechanisms of ROS formation
2023 Guidarelli, Andrea; Spina, Andrea; Buffi, Gloria; Blandino, Giulia; Fiorani, Mara; Cantoni, Orazio
Functional organization of the endoplasmic reticulum dictates the susceptibility of target cells to arsenite-induced mitochondrial superoxide formation, mitochondrial dysfunction and apoptosis
2021 Guidarelli, Andrea; Catalani, Alessia; Spina, Andrea; Varone, Ersilia; Fumagalli, Stefano; Zito, Ester; Fiorani, Mara; Cantoni, Orazio
Inhibition of activity/expression, or genetic deletion, of ERO1α blunts arsenite geno- and cyto-toxicity
2022 Guidarelli, Andrea; Spina, Andrea; Fiorani, Mara; Zito, Ester; Cantoni, Orazio
Pivotal role of ERO1α in the arsenite-dependent regulation of Ca2+ homeostasis and mitochondrial superoxide formation
2023 Spina, Andrea
Unveiling the Link Between NADPH Oxidase 2 Activation and Mitochondrial Superoxide Formation in Leukemic Cell Killing Induced by Arsenic Trioxide
2024 Spina, Andrea; Guidarelli, Andrea; Buffi, Gloria; Fiorani, Mara; Cantoni, Orazio