IRIS

BOTTEGONI, GIOVANNI

BOTTEGONI, GIOVANNI  

Dipartimento di Scienze Biomolecolari (DISB)  

Mostra records
Risultati 1 - 20 di 76 (tempo di esecuzione: 0.025 secondi).
Titolo Data di pubblicazione Autore(i) File
3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease 1-gen-2015 Prati, Federica; DE SIMONE, Angela; Armirotti, Andrea; Summa, Maria; Pizzirani, Daniela; Scarpelli, Rita; Bertozzi, Sine Mandrup; Perez, Daniel I.; Andrisano, Vincenza; Perez Castillo, Ana; Monti, Barbara; Massenzio, Francesca; Polito, Letizia; Racchi, Marco; Sabatino, Piera; Bottegoni, Giovanni; Martinez, Ana; Cavalli, Andrea; Bolognesi, MARIA LAURA
A catalytically silent FAAH-1 variant drives anandamide transport in neurons 1-gen-2012 Fu, J; Bottegoni, G; Sasso, O; Bertorelli, R; Rocchia, W; Masetti, M; Guijarro, A; Lodola, A; Armirotti, A; Garau, G; Bandiera, T; Reggiani, A; Mor, M; Cavalli, A; Piomelli, D
A comparative study on the application of hierarchical-agglomerative clustering approaches to organize outputs of reiterated docking runs 1-gen-2006 Bottegoni, G.; Cavalli, A.; Recanatini, M.
A Computational Study of the Binding of Propidium to the Peripheral Anionic Site of Human Acetylcholinesterase 1-gen-2004 Cavalli, A.; Bottegoni, G.; Raco, C.; DE VIVO, M.; Recanatini, M.
A new method for ligand docking to flexible receptors by dual alanine scanning and refinement (SCARE) 1-gen-2008 Bottegoni, G; Kufareva, I; Totrov, M; Abagyan, R
A Triazolotriazine-Based Dual GSK-3β/CK-1δ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition 1-gen-2019 Redenti, Sara; Marcovich, Irene; De Vita, Teresa; Pérez, Concepción; De Zorzi, Rita; Demitri, Nicola; Perez, Daniel I.; Bottegoni, Giovanni; Bisignano, Paola; Bissaro, Maicol; Moro, Stefano; Martinez, Ana; Storici, Paola; Spalluto, Giampiero; Cavalli, Andrea; Federico, Stephanie
AClAP, Autonomous hierarchical agglomerative Cluster Analysis based protocol to partition conformational datasets 1-gen-2006 Bottegoni, G.; Rocchia, W.; Recanatini, M.; Cavalli, A.
Adiabatic-Bias Molecular Dynamics Simulations Reveal the Impact of Mutations on Muscarinic Antagonist Unbinding Kinetics 1-gen-2025 Coricello, Adriana; Chiaravalle, Anna Lisa; Musgaard, Maria; Gerald Tehan, Benjamin; Elisi, Gian Marco; Bottegoni, Giovanni
An Advanced Multiple Receptor Conformations Virtual Ligand Screening Protocol for the Identification of Novel BACE-1 Inhibitors 1-gen-2011 Kacker, Puneet; Masetti, Matteo; DE SIMONE, Angela; Bottegoni, Giovanni; Cavalli, Andrea
Anandamide transport inhibition by ARN272 attenuates nausea-induced behaviour in rats, and vomiting in shrews (Suncus murinus) 1-gen-2013 O'Brien, L. D.; Limebeer, C. L.; Rock, E. M.; Bottegoni, G; Piomelli, D.; Parker, L. A.
Application of conformational clustering in protein-ligand docking 1-gen-2012 Bottegoni, G; Rocchia, W; Cavalli, A
Application of Deep Learning to Predict the Persistence, Bioaccumulation, and Toxicity of Pharmaceuticals 1-gen-2025 Evangelista, Dominga; Nelson, Elliot; Skyner, Rachael; Tehan, Ben; Bernetti, Mattia; Roberti, Marinella; Bolognesi, Maria Laura; Bottegoni, Giovanni
Applying a multitarget rational drug design strategy: the first set of modulators with potent and balanced activity toward dopamine D3 receptor and fatty acid amide hydrolase 1-gen-2014 De Simone, A; Ruda, Gf; Albani, C; Tarozzo, G; Bandiera, T; Piomelli, D; Cavalli, A; Bottegoni, G
Aryl and heteroaryl N-[4-[4-(2,3-substituted-phenyl)piperazine-1-yl]alkyl] carbamates with improved physico-chemical properties as dual modulators of dopamine D3 receptor and fatty acid amide hydrolase 1-gen-2016 Micoli, A; De Simone, A; Russo, D; Ottonello, G; Colombano, G; Ruda, Gf; Bandiera, T; Cavalli, A; Bottegoni, G
BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease 1-gen-2018 Prati, F; Bottegoni, G; Bolognesi, Ml; Cavalli, A
Benzimidazole derivatives as kinase inhibitors 1-gen-2014 Garuti, L; Roberti, M; Bottegoni, G.
Benzophenone-based derivatives: a novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation 1-gen-2011 Belluti, F; Bartolini, M; Bottegoni, G; Bisi, A; Cavalli, A; Andrisano, V; Rampa, A
BiKi Life Sciences: A New Suite for Molecular Dynamics and Related Methods in Drug Discovery 1-gen-2018 Decherchi, S; Bottegoni, G; Spitaleri, A; Rocchia, W; Cavalli, A
Combining Dyad Protonation and Active Site Plasticity in BACE-1 Structure-Based Drug Design 1-gen-2012 Kacker, P; Masetti, M; Mangold, M; Bottegoni, G; Cavalli, A
Combining Galantamine and Memantine in Multitargeted, New Chemical Entities Potentially Useful in Alzheimer's Disease 1-gen-2012 Simoni, E; Daniele, S; Bottegoni, G; Pizzirani, D; Trincavelli, Ml; Goldoni, L; Tarozzo, G; Reggiani, A; Martini, C; Piomelli, D; Melchiorre, C; Rosini, M; Cavalli, A