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Integrating Large Language Models in Political Discourse Studies on Social Media: Challenges of Validating an LLMs-in-the-loop Pipeline

The integration of Large Language Models (LLMs) into research workflows has the potential to transform the study of political content on social media. This essay discusses a validation protocol addressing three key aspects of LLM-integrated research: the versatility of LLMs as general-purpose models, the granularity and nuance in LLM-uncovered narratives, and the limitations of human assessment capabilities. The protocol includes phases for fine-tuning and validating a binary political classi...

A Snapshot of Vitamin D Status, Performance, Blood Markers, and Dietary Habits in Runners and Non-Runners

Background: Vitamin D can influence athletic performance and infection risk. This study aimed to investigate vitamin D status, hematochemical factors, anthropometric and performance parameters, and dietary habits in runners (n = 23) and sedentary healthy individuals (non-runners, n = 22) during the autumn season. Methods: Both groups had their serum 25-Hydroxyvitamin D (ng/mL) levels, blood and performance parameters, and dietary habits measured. Results: Serum 25-Hydroxyvitamin D levels were...

Advancing the application of chitosan in the pharmaceutical field

Biodegradable lipid bilayer-assisted indocyanine green J- aggregates for photothermal therapy: Formulation, in vitro toxicity and in vivo clearance

Indocyanine green (ICG) J-aggregates (IJA) are a unique form of aggregation that exhibits superior properties to monomeric ICG. Despite their higher photoacoustic (PA) signals for imaging and heating stability during photothermal therapy (PTT), they exhibit low stability under a biological milieu. Our group previously proposed a simple procedure for in-situ preparation of IJA into liposomes, accelerating their formation and optical properties. To comprehend their potential applications, we sy...

The Many Faces of Autophagy: Balancing Survival and Cell Death

: Autophagy and apoptosis are two fundamental biological mechanisms that may cooperate or be antagonistic, and both are involved in deciding the fate of cells in physiological or pathological conditions [...].

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