The dendrimers, polymers with radial symmetry, are able to encapsulate the ions and behave as metal carriers resulting as excellent drugs movers. In this study we used glyco and polypropilen-imine dendrimers that are usually employed in the treatment and prevention of neurodegenerative diseases; phospho-dendrimeri with chemiotherapic functionality, and anti-cancer drugs that can activate TLR7 receptors which are involved in the innate and adaptive immune response. The experiments were conducted through the use of the experimantel technique Electron Paramagnetic Resonance (EPR).
Caratterizzazione di farmaci per la cura del cancro, di malattie neurodegenerative e infiammatorie per mezzo della tecnica EPR
COPPOLA, CONCETTA
2015
Abstract
The dendrimers, polymers with radial symmetry, are able to encapsulate the ions and behave as metal carriers resulting as excellent drugs movers. In this study we used glyco and polypropilen-imine dendrimers that are usually employed in the treatment and prevention of neurodegenerative diseases; phospho-dendrimeri with chemiotherapic functionality, and anti-cancer drugs that can activate TLR7 receptors which are involved in the innate and adaptive immune response. The experiments were conducted through the use of the experimantel technique Electron Paramagnetic Resonance (EPR).File in questo prodotto:
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