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Mostrati risultati da 1 a 20 di 49
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Pyrazolone-based ERO1 inhibitors in ERO1-driven Triple-Negative Breast Cancer and SEPN1-Related Myopathy: Structure-activity relationship and therapeutic potential 1-gen-2025 Retini, Michele; Cherubini, Alessandro; Marrazza, Alice; Varone, Ersilia; Germani, Serena; Renna, Giorgia Maria; Recchia, Adriano; Guidarelli, Andrea; Fumagalli, Stefano; Grasselli, Chiara; Mari, Michele; Piersanti, Giovanni; Bottegoni, Giovanni; Tonelli, Roberto; Gobbi, Marco; Jin, Bo-Ram; Cho, Jaehyung; Cantoni, Orazio; Zito, Ester
Myotube-specific vulnerability to clozapine 1-gen-2025 Buffi, Gloria; Fiorani, Mara; Guidarelli, Andrea; Bagherlou, Nazanin; Spina, Andrea; Scocchia, Lorenzo; Renna, Giorgia Maria; Zito, Ester; Cantoni, Orazio
Small molecule-mediated inhibition of the oxidoreductase ERO1A restrains aggressive breast cancer by impairing VEGF and PD-L1 in the tumor microenvironment 1-gen-2025 Varone, Ersilia; Retini, Michele; Cherubini, Alessandro; Chernorudskiy, Alexander; Marrazza, Alice; Guidarelli, Andrea; Cagnotto, Alfredo; Beeg, Marten; Gobbi, Marco; Fumagalli, Stefano; Bolis, Marco; Guarrera, Luca; Barbera, Maria Chiara; Grasselli, Chiara; Bleve, Augusto; Generali, Daniele; Milani, Manuela; Mari, Michele; Salmona, Mario; Piersanti, Giovanni; Bottegoni, Giovanni; Broggini, Massimo; Janssen-Heininger, Yvonne M. W.; Cho, Jaehyung; Cantoni, Orazio; Zito, Ester
Protocol for measuring force in skinned diaphragm muscle fibers of myopathic SEPN1 knockout mice following chronic tauroursodeoxycholic acid treatment 1-gen-2025 Nogara, Leonardo; Germani, Serena; De Napoli, Cosimo; Blaauw, Bert; Zito, Ester
High fat diet (HFD) induced hepatic lipogenic metabolism and lipotoxicity via Parkin-dependent mitophagy and Errα signal of Pelteobagrus fulvidraco 1-gen-2025 Yu, Angen; Hao, Zhiwei; Wei, Xiaolei; Tan, Xiaoying; Zito, Ester; Zheng, Hua; Luo, Zhi
SEPN1-related myopathy depends on the oxidoreductase ERO1A and is druggable with the chemical chaperone TUDCA 1-gen-2024 Germani, Serena; Van Ho, Andrew Tri; Cherubini, Alessandro; Varone, Ersilia; Chernorudskiy, Alexander; Renna, Giorgia Maria; Fumagalli, Stefano; Gobbi, Marco; Lucchetti, Jacopo; Bolis, Marco; Guarrera, Luca; Craparotta, Ilaria; Rastelli, Giorgia; Piccoli, Giorgia; de Napoli, Cosimo; Nogara, Leonardo; Poggio, Elena; Brini, Marisa; Cattaneo, Angela; Bachi, Angela; Simmen, Thomas; Calì, Tito; Quijano-Roy, Susana; Boncompagni, Simona; Blaauw, Bert; Ferreiro, Ana; Zito, Ester
Fingerprint of the oxido-reductase ERO1: A protein disulfide bond producer and supporter of cancer 1-gen-2024 Zito, Ester; Guarrera, Luca; Janssen-Heininger, Yvonne
ER Oxidative Stress Promotes Glutathione-Dependent Oxidation of Collagen-1A1 and Promotes Lung Fibroblast Activation 1-gen-2024 Druso, Joseph E.; Macpherson1, Maximilian B.; Chia, Shi B.; Elko, Evan; Aboushousha, Reem; Seward, David J.; Abdelhamid, Hend; Erickson, Cuixia; Corteselli, Elizabeth; Tarte, Megan; Peng, Zhihua; Bernier, Daniel; Zito, Ester; Shoulders, Matthew D.; Thannickal5, Victor J.; Huang, Steven; van der Vliet1, Albert; Janssen-Heininger, Vikas Anathy1 and Yvonne M. W.
Selenium Ameliorated Oxidized Fish Oil-Induced Lipotoxicity via the Inhibition of Mitochondrial Oxidative Stress, Remodeling of Usp4-Mediated Deubiquitination, and Stabilization of Pparα 1-gen-2024 Zhang, Dian-Guang; Kunz, Wolfram S; Lei, Xi-Jun; Zito, Ester; Zhao, Tao; Xu, Yi-Chuang; Wei, Xiao-Lei; Lv, Wu-Hong; Luo, Zhi
Chemical chaperones in metabolic fitness beyond protein folding 1-gen-2024 Zito, Ester; Lescure, Alain; Borgese, Nica
Arsenite enhances ERO1α expression via ryanodine receptor dependent and independent mechanisms 1-gen-2023 Guidarelli, Andrea; Spina, Andrea; Fiorani, Mara; Zito, Ester; Cantoni, Orazio
Copper induces liver lipotoxicity disease by up-regulating Nrf2 expression via the activation of MTF-1 and inhibition of SP1/Fyn pathway 1-gen-2023 Zhong, Cc; Zhao, T; Hogstrand, C; Song, Cc; Zito, E; Tan, Xy; Xu, Yc; Song, Yf; Wei, Xl; Luo, Z.
The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria 1-gen-2023 Bassot, A; Chen, J; Takahashi-Yamashiro, K; Yap, Mc; Gibhardt, Cs; Le, Gnt; Hario, S; Nasu, Y; Moore, J; Gutiérrez, T; Mina, L; Mast, H; Moses, A; Bhat, R; Ballanyi, K; Lemieux, H; Sitia, R; Zito, E; Bogeski, I; Campbell, Re; Simmen, T.
Phosphorus Overload Promotes Hepatic Lipolysis by Suppressing GSK3β-Dependent Phosphorylation of PPARα at Ser84 and Thr265 in a Freshwater Teleost 1-gen-2023 Xu, Yi-Chuang; Pantopoulos, Kostas; Zheng, Hua; Zito, Ester; Zhao, Tao; Tan, Xiao-Ying; Wei, Xiao-Lei; Song, Yu-Feng; Luo, Zhi
Influences of five dietary manganese sources on growth, feed utilization, lipid metabolism, antioxidant capacity, inflammatory response and endoplasmic reticulum stress in yellow catfish intestine 1-gen-2023 Xu, Jie-Jie; Jia, Bing-Yu; Zhao, Tao; Tan, Xiao-Ying; Zhang, Dian-Guang; Song, Chang-Chun; Song, Yu-Feng; Zito, Ester; Luo, Zhi
Redox signaling and stress in inherited myopathies 1-gen-2022 Anil Dogan, Sukru; Gioacchin, Giacomo; Zito, Ester; Viscomi, Carlo
Crosstalk between ERO1α and ryanodine receptor in arsenite-dependent mitochondrial ROS formation 1-gen-2022 Spina, Andrea; Guidarelli, Andrea; Fiorani, Mara; Varone, Ersilia; Catalani, Alessia; Zito, Ester; Cantoni, Orazio
ER stress as a trigger of UPR and ER-phagy in cancer growth and spread 1-gen-2022 Cherubini, Alessandro; Zito, Ester
Mitochondrial ROS, ER Stress, and Nrf2 Crosstalk in the Regulation of Mitochondrial Apoptosis Induced by Arsenite 1-gen-2022 Cantoni, Orazio; Zito, Ester; Guidarelli, Andrea; Fiorani, Mara; Ghezzi, Pietro
Regulation of redox signaling in HIF-1-dependent tumor angiogenesis 1-gen-2022 Manuelli, Valeria; Pecorari, Chiara; Filomeni, Giuseppe; Zito, Ester
Mostrati risultati da 1 a 20 di 49
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