Sfoglia per Autore
Low Concentrations of Arsenite Target the Intraluminal Inositol 1, 4, 5-Trisphosphate Receptor/Ryanodine Receptor Crosstalk to Significantly Elevate Intracellular Ca2
2018 Guidarelli, Andrea; Fiorani, Mara; Cantoni, Orazio
Arsenite induces DNA damage via mitochondrial ROS and induction of mitochondrial permeability transition
2017 Guidarelli, Andrea; Fiorani, Mara; Cerioni, Liana; Scotti, Maddalena; Cantoni, Orazio
Intramitochondrial Ascorbic Acid Enhances the Formation of Mitochondrial Superoxide Induced by Peroxynitrite via a Ca(2+)-Independent Mechanism
2017 Guidarelli, Andrea; Cerioni, Liana; Fiorani, Mara; Cantoni, Orazio
Mitochondrial ascorbic acid prevents mitochondrial O2.- formation, an event critical for U937 cell apoptosis induced by arsenite through both autophagic-dependent and independent mechanisms
2016 Guidarelli, Andrea; Carloni, Silvia; Balduini, Walter; Fiorani, Mara; Cantoni, Orazio
Cross-Talk Between NO Synthase Isoforms in Neuro-Inflammation: Possible Implications in HIV-Associated Neurocognitive Disorders
2016 Persichini, Tiziana; Mariotto, Sofia; Suzuki, Hisanori; Butturini, Elena; Mastrantonio, Roberta; Cantoni, Orazio; Colasanti, Marco
The study of the mechanism of arsenite toxicity in respiration-deficient cells reveals that NADPH oxidase-derived superoxide promotes the same downstream events mediated by mitochondrial superoxide in respiration-proficient cells
2016 Guidarelli, Andrea; Fiorani, Mara; Carloni, Silvia; Cerioni, Liana; Balduini, Walter; Cantoni, Orazio
Intracellular dehydroascorbic acid inhibits SVCT2-dependent transport of ascorbic acid in mitochondria
2015 Fiorani, Mara; Azzolini, Catia; Guidarelli, Andrea; Cerioni, Liana; Scotti, Maddalena; Cantoni, Orazio
U937 cell apoptosis induced by arsenite is prevented by low concentrations of mitochondrial ascorbic acid with hardly any effect mediated by the cytosolic fraction of the vitamin
2015 Guidarelli, Andrea; Fiorani, Mara; Catia, Azzolini; Cerioni, Liana; Scotti, Maddalena; Cantoni, Orazio
The mitochondrial transporter of ascorbic acid functions with high affinity in the presence of low millimolar concentrations of sodium and in the absence of calcium and magnesium
2015 Fiorani, Mara; Catia, Azzolini; Cerioni, Liana; Scotti, Maddalena; Guidarelli, Andrea; Ciacci, Caterina; Cantoni, Orazio
Mitochondrial ascorbic acid is responsible for enhanced susceptibility of U937 cells to the toxic effects of peroxynitrite
2014 Guidarelli, Andrea; Cerioni, Liana; Fiorani, Mara; Azzolini, Catia; Cantoni, Orazio
A novel biological role of dehydroascorbic acid: Inhibition of Na+-dependent transport of ascorbic acid.
2014 Fiorani, Mara; Azzolini, Catia; Guidarelli, Andrea; Cerioni, Liana; Cantoni, Orazio
The role of arachidonic acid in the regulation of nitric oxide synthase isoforms by HIV gp120 protein in astroglial cells
2014 Tiziana, Persichini; Roberta, Mastrantonio; Silvia Del, Matto; Palomba, Letizia; Cantoni, Orazio; Marco, Colasanti
Novel SETX variants in a patient with ataxia, neuropathy, and oculomotor apraxia are associated with normal sensitivity to oxidative DNA damaging agents
2014 Chiara, Vantaggiato; Cantoni, Orazio; Guidarelli, Andrea; Romina, Romaniello; Andrea, Citterio; Filippo, Arrigoni; Chiara, Doneda; Marianna, Castelli; Giovanni, Airoldi; Nereo, Bresolin; Renato, Borgatti; Maria Teresa, Bassi
Superoxide dictates the mode of U937 cell ascorbic acid uptake and prevents the enhancing effects of the vitamin to otherwise non-toxic levels of reactive oxygen/nitrogen species
2013 Fiorani, Mara; Azzolini, Catia; Cerioni, Liana; Guidarelli, Andrea; Cantoni, Orazio
Sodium-dependent transport of ascorbic acid in U937 cell mitochondria.
2013 Azzolini, Catia; Fiorani, Mara; Cerioni, Liana; Guidarelli, Andrea; Cantoni, Orazio
A moderate decline in U937 cell GSH levels triggers PI3 kinase/Akt-dependent Bad phosphorylation, thereby preventing an otherwise prompt apoptotic response
2012 Cerioni, Liana; Fiorani, Mara; Azzolini, Catia; Cantoni, Orazio
Studies with low micromolar levels of ascorbic and dehydroascorbic acid fail to unravel a preferential route for vitamin C uptake and accumulation in U937 cells
2012 Azzolini, Catia; Fiorani, Mara; Guidarelli, Andrea; Cantoni, Orazio
A novel nonsense mutation in the APTX gene associated with delayed DNA single-strand break removal fails to enhance sensitivity to different genotoxic agents.
2011 Crimella, C; Cantoni, Orazio; Guidarelli, Andrea; Vantaggiato, C; Martinuzzi, A; Fiorani, Mara; Azzolini, Catia; Orso, G; Bresolin, N; Bassi, M. T.
A novel mechanism, uniquely dependent on mitochondrial calcium accumulation, whereby peroxynitrite promotes formation of superoxide/hydrogen peroxide and the ensuing strand scission of genomic DNA
2010 Guidarelli, Andrea; Fiorani, Mara; Azzolini, Catia; Cantoni, Orazio
Assessing bad sub-cellular localization under conditions associated with prevention or promotion of mitochondrial permeability transition-dependent toxicity.
2010 Cerioni, Liana; Cantoni, Orazio
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