IRIS
TONTINI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 8.238
EU - Europa 6.182
AS - Asia 2.094
OC - Oceania 18
SA - Sud America 17
Continente sconosciuto - Info sul continente non disponibili 13
AF - Africa 9
Totale 16.571
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Nazione #
US - Stati Uniti d'America 8.187
GB - Regno Unito 2.380
CN - Cina 1.511
UA - Ucraina 1.038
IT - Italia 958
SE - Svezia 586
TR - Turchia 379
FI - Finlandia 377
DE - Germania 283
IE - Irlanda 254
FR - Francia 101
RU - Federazione Russa 76
IN - India 51
CA - Canada 48
BE - Belgio 42
SG - Singapore 40
KR - Corea 32
JP - Giappone 31
NL - Olanda 22
VN - Vietnam 18
RO - Romania 16
AU - Australia 15
EU - Europa 12
ES - Italia 9
IR - Iran 9
AT - Austria 7
CH - Svizzera 7
KE - Kenya 7
BR - Brasile 6
PL - Polonia 6
CL - Cile 5
HK - Hong Kong 5
CO - Colombia 3
HU - Ungheria 3
ID - Indonesia 3
NZ - Nuova Zelanda 3
SA - Arabia Saudita 3
SI - Slovenia 3
AL - Albania 2
AM - Armenia 2
FK - Isole Falkland (Malvinas) 2
GR - Grecia 2
IQ - Iraq 2
LU - Lussemburgo 2
MX - Messico 2
NO - Norvegia 2
PK - Pakistan 2
TG - Togo 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
BD - Bangladesh 1
BG - Bulgaria 1
EE - Estonia 1
HR - Croazia 1
JM - Giamaica 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
LV - Lettonia 1
PE - Perù 1
PH - Filippine 1
PT - Portogallo 1
RS - Serbia 1
TW - Taiwan 1
Totale 16.571
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Città #
Southend 2.214
Woodbridge 1.188
Ann Arbor 884
Houston 832
Jacksonville 829
Fairfield 775
Chandler 766
Nanjing 442
Ashburn 391
Cambridge 367
Wilmington 318
Seattle 292
Izmir 287
Dublin 199
Nanchang 178
San Mateo 146
Helsinki 141
Beijing 137
Princeton 119
Hebei 92
Shenyang 91
Changsha 82
New York 75
Tianjin 72
Boardman 69
Jiaxing 63
Istanbul 59
Velikiy Novgorod 56
Düsseldorf 54
Menlo Park 48
Kunming 43
Brussels 41
Bremen 36
San Diego 31
San Francisco 29
Jinan 28
Seongnam 28
Urbino 28
Milan 27
Toronto 27
Des Moines 25
Mülheim 23
Shanghai 23
Lanzhou 22
Venice 22
London 21
Ningbo 21
Rome 21
Changchun 20
Dearborn 20
Munich 20
Singapore 19
Hangzhou 18
Zhengzhou 18
Guangzhou 16
Haikou 16
Ancona 15
Parma 15
Amsterdam 14
Dong Ket 14
Norwalk 14
Taizhou 14
Cava De' Tirreni 13
Palermo 13
Redwood City 13
Auburn Hills 12
Florence 11
Napoli 10
Padova 10
Hefei 9
Leawood 9
Los Angeles 9
Augusta 8
Bologna 8
Messina 8
Naples 8
Osimo 8
West Jordan 8
Borås 7
Vienna 7
Ardabil 6
Fuzhou 6
Melbourne 6
Modugno 6
Turin 6
Bari 5
Berlin 5
Canberra 5
Codogno 5
Edinburgh 5
Falconara Marittima 5
Kiev 5
Madrid 5
Markham 5
Mcallen 5
Monmouth Junction 5
Nuremberg 5
Orange 5
Acton 4
Alessandria 4
Totale 12.269
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Nome #
Inibitori dell’enzima NAAA (N-Acylethanolamine-Hydrolizing Acid Amidase) come nuovi agenti antinfiammatori 735
1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES AS LIGANDS AT THE GLYCINE-BINDING SITE OF THE N-METHYL-D-ASPARTATE RECEPTOR 319
Pharmacokinetics, pharmacodynamics and safety studies on URB 937, a peripherally restricted fatty acid amide hydrolase inhibitor, in rats 312
1-Aminocyclopropane-1-carboxylic acid derivatives as ligands at the glicine-site of the NMDA receptor. 302
Scoperta del primo inibitore dell’enzima idrolasi delle ammidi degli acidi grassi (FAAH) ad azione periferica 238
Structure–Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability 215
Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability 205
A New Synthesis of 2-Substituted DL-Tryptophan Derivatives 203
Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress 201
(E)-3-(2-(N-phenylcarbamoyl)vinyl)pyrrole-2-carboxylic acid derivatives. A novel class of glycine site antagonists. 199
Modulation of Anxiety Through Blockade of Anandamide Hydrolysis 199
Sintesi e studi di relazione struttura-attività/stabilità di carbammati inibitori dell’enzima FAAH 198
A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo 196
Identification of a Bioactive Impurity in a Commercial Sample of 6-Methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754) 192
An improved route to cycloalka[b]pyrrole 2-carboxylates 189
Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats 189
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 188
3-(2-Carbamoylvinyl)-4,5-dimethylpyrrole-2-carboxylic acids as ligands at the NMDA glycine-binding site: a study on the 2-carbamoylvinyl chain modification 187
Synthesis and Biological Evaluation of a γ-Cyclodextrin-based Formulation of the Anticancer Agent 5,6,11,12,17,18,23,24-Octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 181
Synthesis and Structure–Activity Relationships of a Series of Pyrrole Cannabinoid Receptor Agonists 179
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation 177
Endocannabinoids in the Treatment of Mood Disorders: Evidence from Animal Models 176
Peripherally Restricted FAAH Inhibitors 174
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 170
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 168
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis 167
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 166
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 164
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 163
Application of 3D-QSAR in the Rational Design of Receptor Ligands and Enzyme Inhibitors 162
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 160
The Fatty Acid Amide Hydrolase Inhibitor URB597 (Cyclohexylcarbamic Acid 3’-Carbamoylbiphenyl-3-yl Ester) Reduces Neuropathic Pain after Oral Administration in Mice 160
URB602 Inhibits Monoacylglycerol Lipase and Selectively Blocks 2-Arachidonoylglycerol Degradation in Intact Brain Slices 159
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 159
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus 157
The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues 155
O-Biphenyl-3-yl Carbamates as Peripheral FAAH Inhibitors: Synthesis and Structure–Activity (SAR) Relationship Studies 153
Electron Impact Ionization and Fast Atom Bombardment Mass Spectrometry of Some 3,3-Dimethyl-1-(Isoxazol-3-yl)-triazenes. A New Class of Potential Anticancer Agents. 152
Modulation of anxiety through blockade of anandamide hydrolysis 152
Nitroisoxazoles by manganese(IV) oxide oxidation of nitro-4,5-dihydroisoxazoles. 151
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice 151
Sintesi e studi biologici preliminari su analoghi di URB937, il primo inibitore ad azione periferica dell'enzima FAAH 150
2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists 148
A practical and expeditious method for the preparation of the anticancer agent 5,6,11,12,17,18,23,24-octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 147
N-Acyl-5- and -2,5-substituted tryptamines: synthesis, activity and affinity for human mt1 and MT2 melatonin receptors 146
An endocannabinoid mechanism for stress-induced analgesia 146
Application of a non-electrophysiological method to study binding affinity and efficacy of glicine analogs to the glicine site of the NMDA receptor-ion channel complex. 144
N-acetiltriptamine 2,5-sostituite: sintesi e valutazione dell’attività biologica per i recettori melatoninergici MT1 e MT2 143
Selective inhibition of 2 - AG hydrolysis enhances endocannabinoid signaling in the hippocampus 143
Anthranilic acid based CCK1 antagonists: the 2-indole moiety may represent a "needle" according to the recent homonymous concept 141
Pharmacological Profile of the Selective FAAH Inhibitor KDS-4103 (URB597) 140
N-alchil-O-arilcarbammati come inibitori delle idrolasi delle ammidi degli acidi grassi (FAAH): aspetti meccanicistici 139
(E)-3-[2-(Carbamoylvinyl)]pyrrol-2-carboxylic acid derivatives: A novel Class of glycine site Antagonists. 137
Synthesis and Structure–Activity Relationship Studies of O-Biphenyl-3-yl Carbamates as Peripherally Restricted Fatty Acid Amide Hydrolase Inhibitors 136
N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis, Structure–Activity and Structure–Property Relationships 135
Short synthesis of tryptophan and β -carboline derivatives by reaction of indoles with N-(diphenylmethylene)-α ,β -didehydroamino acid esters 133
The CB1 Antagonist/CB2 Agonist URB447 Confers Neuroprotection after Neonatal Hypoxia-ischemia 133
Synthesis and Structure–Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors 130
Anandamide suppressess pain initiation through a peripheral endocannabinoid mechanism 130
Design, SAR and Biological Activity of a New Class of FAAH Inhibitors: Cyclohexyl Carbamic Acid Biphenyl-3-yl Esters 129
SYNTHESIS, BINDING AFFINITY FOR THE MELATONIN RECEPTOR, AND EVALUATION OF THE BIOLOGICAL ACTIVITY OF NEW INDOLE-BASED MELATONIN ANALOGUES. 127
Rotation about the N2-N3 bond in 3,3-dimethyl-1-(isoxazol-3-yl)triazene 126
Characterization of the Fatty Acid Amide Hydrolase Inhibitor Cyclohexyl Carbamic Acid 3'-Carbamoyl-biphenyl-3-yl Ester (URB597): Effects on Anandamide and Oleoylethanolamide Deactivation 126
Synthesis and biological evaluation of 6-bromo-6-substituted penicillanic acid derivatives as beta-lactamase inhibitors. 126
α-Acylamino-β-lactones as a new class of N-acylethanolamine-hydrolyzing acid amidase (NAAA) inhibitors: synthesis and structure–activity relationships 123
Synthesis and Structure-Activity/Stability Relationships of Carbamate Inhibitors of the FAAH Enzyme 123
Mimosine induces apoptosis in the HL60 human tumor cell line. 123
2 - Arachidonoylglycerol and anandamide are endocannabinoid mediators of stress - induced analgesia 122
Synthesis and pharmacological characterization of URB447, a new cannabinoid receptor neutral antagonist 122
ANTIMETASTATIC ACTION OF A NEW ANALOG OF DACARBAZINE IN MICE BEARING LEWIS LUNG CARCINOMA 121
Identification of a Bioactive Impurity Present in a Sample of URB754 121
Antinociceptive effects of the brain-impermeant fatty-acid amide hydrolase inhibitor URB937 120
Tandem mass spectrometric data–FAAH inhibitors activity relationships of some carbamic acid O-aryl esters 119
FAAH and MGL Inhibitors. Design and Therapeutic Implications 119
2-N-Acylaminoalkylindoles: Design and Quantitative Structure-Activity Relationship Studies Leading to MT2-Selective Antagonists. 117
Sintesi e studi di relazione struttura–attività/selettività su O-bifenil-3-ilcarbammati disostituiti quali inibitori periferici dell’enzima FAAH 117
URB602, a Monoacylglycerol Lipase Inhibitor, Protects from the Long-term Consequences of a Neonatal Hypoxic-ischemic Brain Injury in Rats 113
Synthesis of 1-(isoxazol-3-yl)triazene derivatives. Antimetastatic activity of 3,3-dimethyl-1-(5-methylisoxazol-3-yl)triazene. European Journal of Medicinal Chemistry (1996), 31(9), 735-740. 111
Structure-Activity Relationships of Alkylcarbamic Acid Aryl Esters, as Fatty Acid Amide Hydrolase Inhibitors 110
Seamus Heaney: una poesia del movimento 110
Correlation of the antimetastatic properties of aryltriazenes with their Electron Impact Ionization Mass Spectronomy 109
Methods, Compositions, and Other Compounds for Modulation of Monoacylglycerol Lipase Pain, and Stress-related Disorders 109
Design, Synthesis and SAR of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acids Amide Hydrolase Inhibitors 109
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 108
Synthesis and Biological Activity of Monoacylglycerol Lipase (MGL) Inhibitor URB602 and its Analogs 108
QSAR and molecular modelling investigations of a new series of alkyl carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 106
3D-QSAR study of carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 105
Synthesis of new C-6 alkylidene penicillin derivatives as beta-lactamase inhibitors 104
A linear relationship between MS/MS data and FAAH inhibitory activity of some carbamates 102
Insight into the mechanism of carbamate inactivation of FAAH by QM/MM modelling study 100
Mass Spectrometry and Pharmacology Activity: The Case of Carbamic Analogs 100
Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamates FAAH inhibitors 100
Cannabinoids Modify Hippocampal Serotonergic Transmission 98
Inhibitors of lysosomal lipid amidase NAAA 97
Correlation of the mutagenic properties of aryl- and heteroaryl-triazenes with their electron ionization induced fragmentation 95
Differences between direct cannabinoid agonists and FAAH inhibitors on antidepressant-like behavioural and serotonin-modulatory activity 95
Characterization of monoacylglycerol lipase (MGL) inhibitor URB602 94
The Collisional Behavior of ESI-Generated Protonated Molecules of Some Carbamate Bioisosters and its Relationship with their Biological Activity 94
Structure–Activity and Structure–Property Relationships of N-(2-Oxo-3-Oxetanyl)carbamic Acid Esters as N-Acylethanolamine-hydrolyzing Acid Amidase (NAAA) Inhibitors 93
Synthesis and Pharmacological Characterization of Potent and Selective Inhibitors of Fatty Acid Amidohydrolase (FAAH) 90
Totale 15.285
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Categoria #
all - tutte 48.833
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 48.833
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.365 0 104 173 586 97 246 228 256 128 220 107 220
2020/20212.082 127 264 121 223 102 156 93 143 273 178 290 112
2021/20221.321 89 171 142 183 40 36 62 66 87 67 18 360
2022/20232.159 254 135 68 288 186 451 16 174 335 65 113 74
2023/2024569 70 44 51 74 36 120 22 36 10 46 14 46
2024/2025204 109 95 0 0 0 0 0 0 0 0 0 0
Totale 16.712