IRIS
TONTINI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 13.101
EU - Europa 9.176
AS - Asia 4.358
SA - Sud America 317
Continente sconosciuto - Info sul continente non disponibili 156
AF - Africa 53
OC - Oceania 22
Totale 27.183
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Nazione #
US - Stati Uniti d'America 12.902
GB - Regno Unito 2.441
CN - Cina 2.218
NL - Olanda 1.945
IT - Italia 1.212
SG - Singapore 1.149
UA - Ucraina 1.042
SE - Svezia 612
FI - Finlandia 412
RU - Federazione Russa 412
TR - Turchia 399
DE - Germania 397
IE - Irlanda 258
FR - Francia 232
BR - Brasile 226
VN - Vietnam 210
CA - Canada 122
IN - India 90
BE - Belgio 51
JP - Giappone 50
BD - Bangladesh 42
ES - Italia 34
HK - Hong Kong 33
KR - Corea 33
PL - Polonia 32
AR - Argentina 30
MX - Messico 27
IQ - Iraq 21
CO - Colombia 19
AT - Austria 18
ID - Indonesia 18
AU - Australia 17
RO - Romania 17
ZA - Sudafrica 17
KE - Kenya 13
EU - Europa 12
SA - Arabia Saudita 12
CL - Cile 11
HN - Honduras 11
LT - Lituania 11
IR - Iran 10
PK - Pakistan 10
VE - Venezuela 9
CH - Svizzera 8
CR - Costa Rica 8
AE - Emirati Arabi Uniti 7
MY - Malesia 7
EC - Ecuador 6
JM - Giamaica 6
JO - Giordania 6
PH - Filippine 6
PY - Paraguay 6
UZ - Uzbekistan 6
AL - Albania 5
NZ - Nuova Zelanda 5
PE - Perù 5
AZ - Azerbaigian 4
ET - Etiopia 4
GR - Grecia 4
IL - Israele 4
LV - Lettonia 4
MA - Marocco 4
SM - San Marino 4
SV - El Salvador 4
BG - Bulgaria 3
BZ - Belize 3
DO - Repubblica Dominicana 3
EG - Egitto 3
GP - Guadalupe 3
GT - Guatemala 3
HU - Ungheria 3
KG - Kirghizistan 3
PT - Portogallo 3
SI - Slovenia 3
TN - Tunisia 3
TT - Trinidad e Tobago 3
TW - Taiwan 3
AM - Armenia 2
BB - Barbados 2
EE - Estonia 2
FK - Isole Falkland (Malvinas) 2
KW - Kuwait 2
LA - Repubblica Popolare Democratica del Laos 2
LU - Lussemburgo 2
NO - Norvegia 2
NP - Nepal 2
PR - Porto Rico 2
RS - Serbia 2
SY - Repubblica araba siriana 2
TG - Togo 2
TH - Thailandia 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AD - Andorra 1
BM - Bermuda 1
BO - Bolivia 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
CY - Cipro 1
DK - Danimarca 1
Totale 27.027
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Città #
Southend 2.214
Amsterdam 1.921
Dallas 1.281
Woodbridge 1.188
Ann Arbor 885
Ashburn 880
Houston 843
Jacksonville 833
Fairfield 775
Chandler 766
San Jose 649
Singapore 595
Nanjing 442
Cambridge 367
Beijing 337
Wilmington 318
Seattle 296
Izmir 287
Boardman 208
Dublin 202
Council Bluffs 193
Nanchang 178
Helsinki 163
San Mateo 147
New York 144
Princeton 120
Lauterbourg 105
Los Angeles 105
Hebei 92
Santa Clara 91
Shenyang 91
Changsha 83
Ho Chi Minh City 76
Tianjin 76
Munich 69
Düsseldorf 68
Jiaxing 67
Milan 67
Istanbul 61
Velikiy Novgorod 56
Brussels 50
Des Moines 50
Buffalo 48
Menlo Park 48
Shanghai 47
Hanoi 45
Toronto 44
Kunming 43
Moscow 43
Rome 42
San Francisco 41
Guangzhou 38
Bremen 36
London 36
Chicago 32
Orem 31
San Diego 31
Jinan 30
Montreal 30
Atlanta 28
Hong Kong 28
Nuremberg 28
Seongnam 28
Urbino 28
Stockholm 27
Frankfurt am Main 26
São Paulo 25
Warsaw 25
Denver 23
Mülheim 23
Venice 23
Lanzhou 22
Tokyo 22
Ningbo 21
Zhengzhou 21
Changchun 20
Dearborn 20
Hangzhou 20
Brooklyn 19
Chennai 19
Haikou 17
Ancona 16
Naples 16
Phoenix 16
Norwalk 15
Parma 15
Taizhou 15
Dong Ket 14
Florence 14
Manchester 14
Redwood City 14
Shenzhen 14
Vienna 14
Ankara 13
Cava De' Tirreni 13
Charlotte 13
Mexico City 13
Palermo 13
Turku 13
Auburn Hills 12
Totale 18.884
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Nome #
1-Aminocyclopropane-1-carboxylic acid derivatives as ligands at the glicine-site of the NMDA receptor. 3.210
Inibitori dell’enzima NAAA (N-Acylethanolamine-Hydrolizing Acid Amidase) come nuovi agenti antinfiammatori 883
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis 882
1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES AS LIGANDS AT THE GLYCINE-BINDING SITE OF THE N-METHYL-D-ASPARTATE RECEPTOR 443
Pharmacokinetics, pharmacodynamics and safety studies on URB 937, a peripherally restricted fatty acid amide hydrolase inhibitor, in rats 380
Scoperta del primo inibitore dell’enzima idrolasi delle ammidi degli acidi grassi (FAAH) ad azione periferica 368
The Fatty Acid Amide Hydrolase Inhibitor URB597 (Cyclohexylcarbamic Acid 3’-Carbamoylbiphenyl-3-yl Ester) Reduces Neuropathic Pain after Oral Administration in Mice 320
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 307
(E)-3-(2-(N-phenylcarbamoyl)vinyl)pyrrole-2-carboxylic acid derivatives. A novel class of glycine site antagonists. 299
Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress 296
A New Synthesis of 2-Substituted DL-Tryptophan Derivatives 293
3-(2-Carbamoylvinyl)-4,5-dimethylpyrrole-2-carboxylic acids as ligands at the NMDA glycine-binding site: a study on the 2-carbamoylvinyl chain modification 293
A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo 293
Sintesi e studi di relazione struttura-attività/stabilità di carbammati inibitori dell’enzima FAAH 291
An improved route to cycloalka[b]pyrrole 2-carboxylates 276
Structure–Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability 276
Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability 272
Identification of a Bioactive Impurity in a Commercial Sample of 6-Methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754) 261
2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists 254
Application of a non-electrophysiological method to study binding affinity and efficacy of glicine analogs to the glicine site of the NMDA receptor-ion channel complex. 250
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation 250
Synthesis and Biological Evaluation of a γ-Cyclodextrin-based Formulation of the Anticancer Agent 5,6,11,12,17,18,23,24-Octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 250
Anandamide suppressess pain initiation through a peripheral endocannabinoid mechanism 249
Modulation of Anxiety Through Blockade of Anandamide Hydrolysis 240
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 240
An endocannabinoid mechanism for stress-induced analgesia 234
Anthranilic acid based CCK1 antagonists: the 2-indole moiety may represent a "needle" according to the recent homonymous concept 232
(E)-3-[2-(Carbamoylvinyl)]pyrrol-2-carboxylic acid derivatives: A novel Class of glycine site Antagonists. 232
A practical and expeditious method for the preparation of the anticancer agent 5,6,11,12,17,18,23,24-octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 232
Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats 231
N-acetiltriptamine 2,5-sostituite: sintesi e valutazione dell’attività biologica per i recettori melatoninergici MT1 e MT2 230
O-Biphenyl-3-yl Carbamates as Peripheral FAAH Inhibitors: Synthesis and Structure–Activity (SAR) Relationship Studies 228
Synthesis and Structure–Activity Relationships of a Series of Pyrrole Cannabinoid Receptor Agonists 221
Peripherally Restricted FAAH Inhibitors 221
2-N-Acylaminoalkylindoles: Design and Quantitative Structure-Activity Relationship Studies Leading to MT2-Selective Antagonists. 220
N-Acyl-5- and -2,5-substituted tryptamines: synthesis, activity and affinity for human mt1 and MT2 melatonin receptors 218
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 213
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 211
Sintesi e studi biologici preliminari su analoghi di URB937, il primo inibitore ad azione periferica dell'enzima FAAH 211
SYNTHESIS, BINDING AFFINITY FOR THE MELATONIN RECEPTOR, AND EVALUATION OF THE BIOLOGICAL ACTIVITY OF NEW INDOLE-BASED MELATONIN ANALOGUES. 210
2 - Arachidonoylglycerol and anandamide are endocannabinoid mediators of stress - induced analgesia 207
Endocannabinoids in the Treatment of Mood Disorders: Evidence from Animal Models 206
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 205
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus 201
URB602 Inhibits Monoacylglycerol Lipase and Selectively Blocks 2-Arachidonoylglycerol Degradation in Intact Brain Slices 200
Modulation of anxiety through blockade of anandamide hydrolysis 200
N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis, Structure–Activity and Structure–Property Relationships 198
Electron Impact Ionization and Fast Atom Bombardment Mass Spectrometry of Some 3,3-Dimethyl-1-(Isoxazol-3-yl)-triazenes. A New Class of Potential Anticancer Agents. 197
Synthesis and Structure–Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors 196
α-Acylamino-β-lactones as a new class of N-acylethanolamine-hydrolyzing acid amidase (NAAA) inhibitors: synthesis and structure–activity relationships 195
ANTIMETASTATIC ACTION OF A NEW ANALOG OF DACARBAZINE IN MICE BEARING LEWIS LUNG CARCINOMA 194
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 194
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 193
Nitroisoxazoles by manganese(IV) oxide oxidation of nitro-4,5-dihydroisoxazoles. 192
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice 191
Application of 3D-QSAR in the Rational Design of Receptor Ligands and Enzyme Inhibitors 191
The CB1 Antagonist/CB2 Agonist URB447 Confers Neuroprotection after Neonatal Hypoxia-ischemia 190
Synthesis and Structure–Activity Relationship Studies of O-Biphenyl-3-yl Carbamates as Peripherally Restricted Fatty Acid Amide Hydrolase Inhibitors 190
Pharmacological Profile of the Selective FAAH Inhibitor KDS-4103 (URB597) 189
The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues 189
Synthesis and Structure-Activity/Stability Relationships of Carbamate Inhibitors of the FAAH Enzyme 188
Sintesi e studi di relazione struttura–attività/selettività su O-bifenil-3-ilcarbammati disostituiti quali inibitori periferici dell’enzima FAAH 188
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 186
Synthesis and biological evaluation of 6-bromo-6-substituted penicillanic acid derivatives as beta-lactamase inhibitors. 183
N-alchil-O-arilcarbammati come inibitori delle idrolasi delle ammidi degli acidi grassi (FAAH): aspetti meccanicistici 182
A linear relationship between MS/MS data and FAAH inhibitory activity of some carbamates 180
Short synthesis of tryptophan and β -carboline derivatives by reaction of indoles with N-(diphenylmethylene)-α ,β -didehydroamino acid esters 177
Identification of a Bioactive Impurity Present in a Sample of URB754 176
Mimosine induces apoptosis in the HL60 human tumor cell line. 176
Selective inhibition of 2 - AG hydrolysis enhances endocannabinoid signaling in the hippocampus 174
Rotation about the N2-N3 bond in 3,3-dimethyl-1-(isoxazol-3-yl)triazene 170
3D-QSAR study of carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 169
Characterization of the Fatty Acid Amide Hydrolase Inhibitor Cyclohexyl Carbamic Acid 3'-Carbamoyl-biphenyl-3-yl Ester (URB597): Effects on Anandamide and Oleoylethanolamide Deactivation 168
Antinociceptive effects of the brain-impermeant fatty-acid amide hydrolase inhibitor URB937 163
Design, SAR and Biological Activity of a New Class of FAAH Inhibitors: Cyclohexyl Carbamic Acid Biphenyl-3-yl Esters 162
Synthesis and pharmacological characterization of URB447, a new cannabinoid receptor neutral antagonist 159
QSAR and molecular modelling investigations of a new series of alkyl carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 157
Synthesis of 1-(isoxazol-3-yl)triazene derivatives. Antimetastatic activity of 3,3-dimethyl-1-(5-methylisoxazol-3-yl)triazene. European Journal of Medicinal Chemistry (1996), 31(9), 735-740. 156
Inhibitors of lysosomal lipid amidase NAAA 156
Tandem mass spectrometric data–FAAH inhibitors activity relationships of some carbamic acid O-aryl esters 155
Synthesis of new C-6 alkylidene penicillin derivatives as beta-lactamase inhibitors 153
Structure-Activity Relationships of Alkylcarbamic Acid Aryl Esters, as Fatty Acid Amide Hydrolase Inhibitors 151
Correlation of the antimetastatic properties of aryltriazenes with their Electron Impact Ionization Mass Spectronomy 150
URB602, a Monoacylglycerol Lipase Inhibitor, Protects from the Long-term Consequences of a Neonatal Hypoxic-ischemic Brain Injury in Rats 150
Design, Synthesis and SAR of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acids Amide Hydrolase Inhibitors 150
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 149
Seamus Heaney: una poesia del movimento 148
FAAH and MGL Inhibitors. Design and Therapeutic Implications 147
Methods, Compositions, and Other Compounds for Modulation of Monoacylglycerol Lipase Pain, and Stress-related Disorders 145
Cannabinoids Modify Hippocampal Serotonergic Transmission 143
Structure–Activity and Structure–Property Relationships of N-(2-Oxo-3-Oxetanyl)carbamic Acid Esters as N-Acylethanolamine-hydrolyzing Acid Amidase (NAAA) Inhibitors 140
Synthesis and Pharmacological Characterization of Potent and Selective Inhibitors of Fatty Acid Amidohydrolase (FAAH) 140
Correlation of the mutagenic properties of aryl- and heteroaryl-triazenes with their electron ionization induced fragmentation 136
Synthesis, QSAR and Pharmacological Evaluation of Alkylcarbamic Acid Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: A Novel Approach to Antianxiety and Analgesic Agents 136
Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamates FAAH inhibitors 136
Insight into the mechanism of carbamate inactivation of FAAH by QM/MM modelling study 133
Reactivity, metabolic stability and interaction at the catalytic site for carbamate inhibitors of FAAH 133
Chemical Determinants of Fatty Acid Amide Hydrolase Inactivation Explored by QM/MM Mechanistic Modelling 132
Synthesis and Biological Activity of Monoacylglycerol Lipase (MGL) Inhibitor URB602 and its Analogs 132
Mass Spectrometry and Pharmacology Activity: The Case of Carbamic Analogs 131
Totale 24.898
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Categoria #
all - tutte 84.611
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 84.611
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022919 0 0 0 183 40 36 62 66 87 67 18 360
2022/20232.159 254 135 68 288 186 451 16 174 335 65 113 74
2023/2024569 70 44 51 74 36 120 22 36 10 46 14 46
2024/20251.891 109 104 474 128 59 146 216 94 156 131 137 137
2025/20267.230 381 698 1.214 773 357 359 571 138 2.102 305 210 122
2026/20271.554 744 126 420 264 0 0 0 0 0 0 0 0
Totale 27.183