IRIS
TONTINI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 8.213
EU - Europa 6.132
AS - Asia 1.918
OC - Oceania 18
SA - Sud America 17
Continente sconosciuto - Info sul continente non disponibili 13
AF - Africa 2
Totale 16.313
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Nazione #
US - Stati Uniti d'America 8.162
GB - Regno Unito 2.379
CN - Cina 1.436
UA - Ucraina 1.038
IT - Italia 937
SE - Svezia 586
FI - Finlandia 376
TR - Turchia 297
DE - Germania 274
IE - Irlanda 254
FR - Francia 101
RU - Federazione Russa 70
IN - India 51
CA - Canada 48
BE - Belgio 42
KR - Corea 32
JP - Giappone 30
SG - Singapore 24
VN - Vietnam 18
RO - Romania 16
AU - Australia 15
EU - Europa 12
NL - Olanda 12
IR - Iran 9
ES - Italia 8
AT - Austria 7
CH - Svizzera 7
BR - Brasile 6
CL - Cile 5
HK - Hong Kong 5
PL - Polonia 5
CO - Colombia 3
HU - Ungheria 3
ID - Indonesia 3
NZ - Nuova Zelanda 3
SA - Arabia Saudita 3
SI - Slovenia 3
AL - Albania 2
AM - Armenia 2
FK - Isole Falkland (Malvinas) 2
GR - Grecia 2
IQ - Iraq 2
LU - Lussemburgo 2
MX - Messico 2
NO - Norvegia 2
PK - Pakistan 2
TG - Togo 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BD - Bangladesh 1
BG - Bulgaria 1
EE - Estonia 1
HR - Croazia 1
JM - Giamaica 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
LV - Lettonia 1
PE - Perù 1
PH - Filippine 1
PT - Portogallo 1
RS - Serbia 1
Totale 16.313
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Città #
Southend 2.214
Woodbridge 1.188
Ann Arbor 884
Houston 832
Jacksonville 829
Fairfield 775
Chandler 766
Nanjing 441
Ashburn 388
Cambridge 367
Wilmington 318
Seattle 292
Izmir 287
Dublin 199
Nanchang 178
San Mateo 146
Helsinki 140
Beijing 132
Princeton 119
Hebei 92
Shenyang 91
Changsha 82
New York 75
Tianjin 72
Jiaxing 59
Velikiy Novgorod 56
Düsseldorf 54
Boardman 52
Menlo Park 48
Kunming 43
Brussels 41
Bremen 36
San Diego 31
San Francisco 29
Jinan 28
Seongnam 28
Urbino 28
Toronto 27
Des Moines 25
Milan 23
Mülheim 23
Lanzhou 22
Venice 22
Ningbo 21
Changchun 20
Dearborn 20
London 20
Rome 20
Hangzhou 18
Zhengzhou 18
Haikou 16
Shanghai 16
Ancona 15
Parma 15
Dong Ket 14
Norwalk 14
Cava De' Tirreni 13
Redwood City 13
Taizhou 13
Auburn Hills 12
Munich 12
Florence 11
Palermo 11
Napoli 10
Padova 10
Guangzhou 9
Hefei 9
Leawood 9
Los Angeles 9
Singapore 9
Augusta 8
Bologna 8
Messina 8
Osimo 8
West Jordan 8
Borås 7
Vienna 7
Ardabil 6
Fuzhou 6
Melbourne 6
Modugno 6
Naples 6
Turin 6
Bari 5
Berlin 5
Canberra 5
Codogno 5
Edinburgh 5
Falconara Marittima 5
Kiev 5
Markham 5
Mcallen 5
Monmouth Junction 5
Orange 5
Acton 4
Alessandria 4
Amsterdam 4
Calgary 4
Civitanova Marche 4
Focsani 4
Totale 12.128
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Nome #
Inibitori dell’enzima NAAA (N-Acylethanolamine-Hydrolizing Acid Amidase) come nuovi agenti antinfiammatori 723
Pharmacokinetics, pharmacodynamics and safety studies on URB 937, a peripherally restricted fatty acid amide hydrolase inhibitor, in rats 310
1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES AS LIGANDS AT THE GLYCINE-BINDING SITE OF THE N-METHYL-D-ASPARTATE RECEPTOR 303
1-Aminocyclopropane-1-carboxylic acid derivatives as ligands at the glicine-site of the NMDA receptor. 285
Scoperta del primo inibitore dell’enzima idrolasi delle ammidi degli acidi grassi (FAAH) ad azione periferica 233
Structure–Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability 213
A New Synthesis of 2-Substituted DL-Tryptophan Derivatives 202
Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability 202
Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress 199
Modulation of Anxiety Through Blockade of Anandamide Hydrolysis 197
Sintesi e studi di relazione struttura-attività/stabilità di carbammati inibitori dell’enzima FAAH 197
(E)-3-(2-(N-phenylcarbamoyl)vinyl)pyrrole-2-carboxylic acid derivatives. A novel class of glycine site antagonists. 196
A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo 193
Identification of a Bioactive Impurity in a Commercial Sample of 6-Methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754) 191
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 187
An improved route to cycloalka[b]pyrrole 2-carboxylates 186
Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats 186
3-(2-Carbamoylvinyl)-4,5-dimethylpyrrole-2-carboxylic acids as ligands at the NMDA glycine-binding site: a study on the 2-carbamoylvinyl chain modification 184
Synthesis and Biological Evaluation of a γ-Cyclodextrin-based Formulation of the Anticancer Agent 5,6,11,12,17,18,23,24-Octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 180
Synthesis and Structure–Activity Relationships of a Series of Pyrrole Cannabinoid Receptor Agonists 178
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation 175
Endocannabinoids in the Treatment of Mood Disorders: Evidence from Animal Models 174
Peripherally Restricted FAAH Inhibitors 173
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 168
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 167
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis 165
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 164
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 162
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 161
Application of 3D-QSAR in the Rational Design of Receptor Ligands and Enzyme Inhibitors 160
URB602 Inhibits Monoacylglycerol Lipase and Selectively Blocks 2-Arachidonoylglycerol Degradation in Intact Brain Slices 159
The Fatty Acid Amide Hydrolase Inhibitor URB597 (Cyclohexylcarbamic Acid 3’-Carbamoylbiphenyl-3-yl Ester) Reduces Neuropathic Pain after Oral Administration in Mice 159
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 158
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 157
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus 155
The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues 154
Electron Impact Ionization and Fast Atom Bombardment Mass Spectrometry of Some 3,3-Dimethyl-1-(Isoxazol-3-yl)-triazenes. A New Class of Potential Anticancer Agents. 152
Modulation of anxiety through blockade of anandamide hydrolysis 152
Nitroisoxazoles by manganese(IV) oxide oxidation of nitro-4,5-dihydroisoxazoles. 150
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice 150
Sintesi e studi biologici preliminari su analoghi di URB937, il primo inibitore ad azione periferica dell'enzima FAAH 149
O-Biphenyl-3-yl Carbamates as Peripheral FAAH Inhibitors: Synthesis and Structure–Activity (SAR) Relationship Studies 149
An endocannabinoid mechanism for stress-induced analgesia 146
2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists 146
A practical and expeditious method for the preparation of the anticancer agent 5,6,11,12,17,18,23,24-octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 144
N-Acyl-5- and -2,5-substituted tryptamines: synthesis, activity and affinity for human mt1 and MT2 melatonin receptors 143
Selective inhibition of 2 - AG hydrolysis enhances endocannabinoid signaling in the hippocampus 143
Application of a non-electrophysiological method to study binding affinity and efficacy of glicine analogs to the glicine site of the NMDA receptor-ion channel complex. 141
N-acetiltriptamine 2,5-sostituite: sintesi e valutazione dell’attività biologica per i recettori melatoninergici MT1 e MT2 140
Anthranilic acid based CCK1 antagonists: the 2-indole moiety may represent a "needle" according to the recent homonymous concept 139
Pharmacological Profile of the Selective FAAH Inhibitor KDS-4103 (URB597) 139
N-alchil-O-arilcarbammati come inibitori delle idrolasi delle ammidi degli acidi grassi (FAAH): aspetti meccanicistici 137
(E)-3-[2-(Carbamoylvinyl)]pyrrol-2-carboxylic acid derivatives: A novel Class of glycine site Antagonists. 134
Synthesis and Structure–Activity Relationship Studies of O-Biphenyl-3-yl Carbamates as Peripherally Restricted Fatty Acid Amide Hydrolase Inhibitors 133
N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis, Structure–Activity and Structure–Property Relationships 132
Short synthesis of tryptophan and β -carboline derivatives by reaction of indoles with N-(diphenylmethylene)-α ,β -didehydroamino acid esters 131
Synthesis and Structure–Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors 130
The CB1 Antagonist/CB2 Agonist URB447 Confers Neuroprotection after Neonatal Hypoxia-ischemia 129
Design, SAR and Biological Activity of a New Class of FAAH Inhibitors: Cyclohexyl Carbamic Acid Biphenyl-3-yl Esters 128
Anandamide suppressess pain initiation through a peripheral endocannabinoid mechanism 128
Rotation about the N2-N3 bond in 3,3-dimethyl-1-(isoxazol-3-yl)triazene 126
Characterization of the Fatty Acid Amide Hydrolase Inhibitor Cyclohexyl Carbamic Acid 3'-Carbamoyl-biphenyl-3-yl Ester (URB597): Effects on Anandamide and Oleoylethanolamide Deactivation 125
Synthesis and biological evaluation of 6-bromo-6-substituted penicillanic acid derivatives as beta-lactamase inhibitors. 125
SYNTHESIS, BINDING AFFINITY FOR THE MELATONIN RECEPTOR, AND EVALUATION OF THE BIOLOGICAL ACTIVITY OF NEW INDOLE-BASED MELATONIN ANALOGUES. 123
Synthesis and Structure-Activity/Stability Relationships of Carbamate Inhibitors of the FAAH Enzyme 120
Mimosine induces apoptosis in the HL60 human tumor cell line. 120
Tandem mass spectrometric data–FAAH inhibitors activity relationships of some carbamic acid O-aryl esters 119
Identification of a Bioactive Impurity Present in a Sample of URB754 119
Antinociceptive effects of the brain-impermeant fatty-acid amide hydrolase inhibitor URB937 119
ANTIMETASTATIC ACTION OF A NEW ANALOG OF DACARBAZINE IN MICE BEARING LEWIS LUNG CARCINOMA 118
α-Acylamino-β-lactones as a new class of N-acylethanolamine-hydrolyzing acid amidase (NAAA) inhibitors: synthesis and structure–activity relationships 118
2 - Arachidonoylglycerol and anandamide are endocannabinoid mediators of stress - induced analgesia 118
Synthesis and pharmacological characterization of URB447, a new cannabinoid receptor neutral antagonist 118
FAAH and MGL Inhibitors. Design and Therapeutic Implications 118
Sintesi e studi di relazione struttura–attività/selettività su O-bifenil-3-ilcarbammati disostituiti quali inibitori periferici dell’enzima FAAH 116
2-N-Acylaminoalkylindoles: Design and Quantitative Structure-Activity Relationship Studies Leading to MT2-Selective Antagonists. 115
Synthesis of 1-(isoxazol-3-yl)triazene derivatives. Antimetastatic activity of 3,3-dimethyl-1-(5-methylisoxazol-3-yl)triazene. European Journal of Medicinal Chemistry (1996), 31(9), 735-740. 110
URB602, a Monoacylglycerol Lipase Inhibitor, Protects from the Long-term Consequences of a Neonatal Hypoxic-ischemic Brain Injury in Rats 110
Structure-Activity Relationships of Alkylcarbamic Acid Aryl Esters, as Fatty Acid Amide Hydrolase Inhibitors 109
Seamus Heaney: una poesia del movimento 109
Correlation of the antimetastatic properties of aryltriazenes with their Electron Impact Ionization Mass Spectronomy 108
Design, Synthesis and SAR of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acids Amide Hydrolase Inhibitors 107
Methods, Compositions, and Other Compounds for Modulation of Monoacylglycerol Lipase Pain, and Stress-related Disorders 106
Synthesis and Biological Activity of Monoacylglycerol Lipase (MGL) Inhibitor URB602 and its Analogs 106
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 105
QSAR and molecular modelling investigations of a new series of alkyl carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 102
3D-QSAR study of carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 102
Synthesis of new C-6 alkylidene penicillin derivatives as beta-lactamase inhibitors 101
A linear relationship between MS/MS data and FAAH inhibitory activity of some carbamates 100
Insight into the mechanism of carbamate inactivation of FAAH by QM/MM modelling study 99
Mass Spectrometry and Pharmacology Activity: The Case of Carbamic Analogs 98
Cannabinoids Modify Hippocampal Serotonergic Transmission 97
Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamates FAAH inhibitors 97
Inhibitors of lysosomal lipid amidase NAAA 96
Differences between direct cannabinoid agonists and FAAH inhibitors on antidepressant-like behavioural and serotonin-modulatory activity 95
Correlation of the mutagenic properties of aryl- and heteroaryl-triazenes with their electron ionization induced fragmentation 94
The Collisional Behavior of ESI-Generated Protonated Molecules of Some Carbamate Bioisosters and its Relationship with their Biological Activity 92
Characterization of monoacylglycerol lipase (MGL) inhibitor URB602 91
Structure–Activity and Structure–Property Relationships of N-(2-Oxo-3-Oxetanyl)carbamic Acid Esters as N-Acylethanolamine-hydrolyzing Acid Amidase (NAAA) Inhibitors 91
Sintesi convergente di derivati triptofanici 2-sostituiti 88
Totale 15.051
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Categoria #
all - tutte 43.363
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 43.363
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019749 0 0 0 0 0 0 0 0 0 0 182 567
2019/20203.118 753 104 173 586 97 246 228 256 128 220 107 220
2020/20212.082 127 264 121 223 102 156 93 143 273 178 290 112
2021/20221.321 89 171 142 183 40 36 62 66 87 67 18 360
2022/20232.159 254 135 68 288 186 451 16 174 335 65 113 74
2023/2024515 70 44 51 74 36 120 22 36 10 46 6 0
Totale 16.454