IRIS
TONTINI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 8.461
EU - Europa 6.255
AS - Asia 2.462
OC - Oceania 19
SA - Sud America 19
AF - Africa 14
Continente sconosciuto - Info sul continente non disponibili 13
Totale 17.243
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Nazione #
US - Stati Uniti d'America 8.410
GB - Regno Unito 2.381
CN - Cina 1.638
UA - Ucraina 1.038
IT - Italia 984
SE - Svezia 586
FI - Finlandia 379
TR - Turchia 379
DE - Germania 306
SG - Singapore 279
IE - Irlanda 254
FR - Francia 103
RU - Federazione Russa 76
IN - India 51
CA - Canada 48
BE - Belgio 46
KR - Corea 32
NL - Olanda 32
JP - Giappone 31
VN - Vietnam 18
RO - Romania 16
AU - Australia 15
EU - Europa 12
ES - Italia 11
KE - Kenya 10
IR - Iran 9
AT - Austria 8
CH - Svizzera 7
BR - Brasile 6
HK - Hong Kong 6
PL - Polonia 6
CL - Cile 5
NZ - Nuova Zelanda 4
SA - Arabia Saudita 4
CO - Colombia 3
HU - Ungheria 3
ID - Indonesia 3
PE - Perù 3
SI - Slovenia 3
AL - Albania 2
AM - Armenia 2
FK - Isole Falkland (Malvinas) 2
GR - Grecia 2
IQ - Iraq 2
LU - Lussemburgo 2
MX - Messico 2
NO - Norvegia 2
PK - Pakistan 2
PT - Portogallo 2
TG - Togo 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
BD - Bangladesh 1
BG - Bulgaria 1
EE - Estonia 1
HR - Croazia 1
JM - Giamaica 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
LT - Lituania 1
LV - Lettonia 1
MA - Marocco 1
PH - Filippine 1
RS - Serbia 1
SC - Seychelles 1
TW - Taiwan 1
Totale 17.243
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Città #
Southend 2.214
Woodbridge 1.188
Ann Arbor 884
Houston 832
Jacksonville 829
Fairfield 775
Chandler 766
Nanjing 442
Ashburn 393
Cambridge 367
Wilmington 318
Seattle 292
Izmir 287
Singapore 217
Dublin 199
Boardman 188
Nanchang 178
San Mateo 146
Helsinki 143
Beijing 140
Princeton 119
Hebei 92
Shenyang 91
Changsha 82
New York 75
Tianjin 72
Jiaxing 67
Istanbul 59
Velikiy Novgorod 56
Düsseldorf 54
Menlo Park 48
Brussels 45
Kunming 43
Munich 42
Shanghai 39
Bremen 36
Guangzhou 33
San Diego 31
Santa Clara 31
San Francisco 30
Milan 29
Jinan 28
Seongnam 28
Urbino 28
Toronto 27
Des Moines 25
Mülheim 23
Rome 23
Lanzhou 22
Venice 22
London 21
Ningbo 21
Changchun 20
Dearborn 20
Amsterdam 19
Hangzhou 19
Zhengzhou 18
Ancona 16
Haikou 16
Parma 15
Taizhou 15
Dong Ket 14
Norwalk 14
Cava De' Tirreni 13
Palermo 13
Redwood City 13
Auburn Hills 12
Florence 12
Shenzhen 11
Los Angeles 10
Napoli 10
Padova 10
Hefei 9
Leawood 9
Augusta 8
Bologna 8
Messina 8
Naples 8
Osimo 8
Vienna 8
West Jordan 8
Wuxi 8
Bari 7
Borås 7
Ardabil 6
Fuzhou 6
Melbourne 6
Modugno 6
Nairobi 6
Turin 6
Berlin 5
Canberra 5
Codogno 5
Edinburgh 5
Falconara Marittima 5
Kiev 5
Madrid 5
Markham 5
Mcallen 5
Monmouth Junction 5
Totale 12.712
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Nome #
Inibitori dell’enzima NAAA (N-Acylethanolamine-Hydrolizing Acid Amidase) come nuovi agenti antinfiammatori 768
1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES AS LIGANDS AT THE GLYCINE-BINDING SITE OF THE N-METHYL-D-ASPARTATE RECEPTOR 329
1-Aminocyclopropane-1-carboxylic acid derivatives as ligands at the glicine-site of the NMDA receptor. 317
Pharmacokinetics, pharmacodynamics and safety studies on URB 937, a peripherally restricted fatty acid amide hydrolase inhibitor, in rats 314
Scoperta del primo inibitore dell’enzima idrolasi delle ammidi degli acidi grassi (FAAH) ad azione periferica 249
Structure–Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability 223
A New Synthesis of 2-Substituted DL-Tryptophan Derivatives 211
Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability 210
Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress 209
(E)-3-(2-(N-phenylcarbamoyl)vinyl)pyrrole-2-carboxylic acid derivatives. A novel class of glycine site antagonists. 205
Modulation of Anxiety Through Blockade of Anandamide Hydrolysis 205
Sintesi e studi di relazione struttura-attività/stabilità di carbammati inibitori dell’enzima FAAH 204
A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo 204
Identification of a Bioactive Impurity in a Commercial Sample of 6-Methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754) 202
An improved route to cycloalka[b]pyrrole 2-carboxylates 195
3-(2-Carbamoylvinyl)-4,5-dimethylpyrrole-2-carboxylic acids as ligands at the NMDA glycine-binding site: a study on the 2-carbamoylvinyl chain modification 195
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 195
Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats 193
Synthesis and Biological Evaluation of a γ-Cyclodextrin-based Formulation of the Anticancer Agent 5,6,11,12,17,18,23,24-Octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 191
Synthesis and Structure–Activity Relationships of a Series of Pyrrole Cannabinoid Receptor Agonists 184
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation 184
Endocannabinoids in the Treatment of Mood Disorders: Evidence from Animal Models 181
Peripherally Restricted FAAH Inhibitors 178
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis 177
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 174
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 173
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 171
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 171
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 166
Application of 3D-QSAR in the Rational Design of Receptor Ligands and Enzyme Inhibitors 166
The Fatty Acid Amide Hydrolase Inhibitor URB597 (Cyclohexylcarbamic Acid 3’-Carbamoylbiphenyl-3-yl Ester) Reduces Neuropathic Pain after Oral Administration in Mice 165
URB602 Inhibits Monoacylglycerol Lipase and Selectively Blocks 2-Arachidonoylglycerol Degradation in Intact Brain Slices 164
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 163
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus 162
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 162
The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues 160
O-Biphenyl-3-yl Carbamates as Peripheral FAAH Inhibitors: Synthesis and Structure–Activity (SAR) Relationship Studies 159
Nitroisoxazoles by manganese(IV) oxide oxidation of nitro-4,5-dihydroisoxazoles. 157
Modulation of anxiety through blockade of anandamide hydrolysis 157
2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists 157
Electron Impact Ionization and Fast Atom Bombardment Mass Spectrometry of Some 3,3-Dimethyl-1-(Isoxazol-3-yl)-triazenes. A New Class of Potential Anticancer Agents. 156
An endocannabinoid mechanism for stress-induced analgesia 155
Sintesi e studi biologici preliminari su analoghi di URB937, il primo inibitore ad azione periferica dell'enzima FAAH 155
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice 154
A practical and expeditious method for the preparation of the anticancer agent 5,6,11,12,17,18,23,24-octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 154
N-Acyl-5- and -2,5-substituted tryptamines: synthesis, activity and affinity for human mt1 and MT2 melatonin receptors 152
Application of a non-electrophysiological method to study binding affinity and efficacy of glicine analogs to the glicine site of the NMDA receptor-ion channel complex. 152
N-acetiltriptamine 2,5-sostituite: sintesi e valutazione dell’attività biologica per i recettori melatoninergici MT1 e MT2 149
Anthranilic acid based CCK1 antagonists: the 2-indole moiety may represent a "needle" according to the recent homonymous concept 148
Selective inhibition of 2 - AG hydrolysis enhances endocannabinoid signaling in the hippocampus 147
Pharmacological Profile of the Selective FAAH Inhibitor KDS-4103 (URB597) 145
(E)-3-[2-(Carbamoylvinyl)]pyrrol-2-carboxylic acid derivatives: A novel Class of glycine site Antagonists. 143
N-alchil-O-arilcarbammati come inibitori delle idrolasi delle ammidi degli acidi grassi (FAAH): aspetti meccanicistici 142
N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis, Structure–Activity and Structure–Property Relationships 142
Short synthesis of tryptophan and β -carboline derivatives by reaction of indoles with N-(diphenylmethylene)-α ,β -didehydroamino acid esters 139
Synthesis and Structure–Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors 139
Synthesis and Structure–Activity Relationship Studies of O-Biphenyl-3-yl Carbamates as Peripherally Restricted Fatty Acid Amide Hydrolase Inhibitors 139
Anandamide suppressess pain initiation through a peripheral endocannabinoid mechanism 138
The CB1 Antagonist/CB2 Agonist URB447 Confers Neuroprotection after Neonatal Hypoxia-ischemia 137
Design, SAR and Biological Activity of a New Class of FAAH Inhibitors: Cyclohexyl Carbamic Acid Biphenyl-3-yl Esters 133
2 - Arachidonoylglycerol and anandamide are endocannabinoid mediators of stress - induced analgesia 132
Rotation about the N2-N3 bond in 3,3-dimethyl-1-(isoxazol-3-yl)triazene 131
α-Acylamino-β-lactones as a new class of N-acylethanolamine-hydrolyzing acid amidase (NAAA) inhibitors: synthesis and structure–activity relationships 131
Synthesis and biological evaluation of 6-bromo-6-substituted penicillanic acid derivatives as beta-lactamase inhibitors. 131
Characterization of the Fatty Acid Amide Hydrolase Inhibitor Cyclohexyl Carbamic Acid 3'-Carbamoyl-biphenyl-3-yl Ester (URB597): Effects on Anandamide and Oleoylethanolamide Deactivation 130
Identification of a Bioactive Impurity Present in a Sample of URB754 130
SYNTHESIS, BINDING AFFINITY FOR THE MELATONIN RECEPTOR, AND EVALUATION OF THE BIOLOGICAL ACTIVITY OF NEW INDOLE-BASED MELATONIN ANALOGUES. 130
Synthesis and Structure-Activity/Stability Relationships of Carbamate Inhibitors of the FAAH Enzyme 128
Mimosine induces apoptosis in the HL60 human tumor cell line. 127
ANTIMETASTATIC ACTION OF A NEW ANALOG OF DACARBAZINE IN MICE BEARING LEWIS LUNG CARCINOMA 126
Synthesis and pharmacological characterization of URB447, a new cannabinoid receptor neutral antagonist 125
Antinociceptive effects of the brain-impermeant fatty-acid amide hydrolase inhibitor URB937 125
Tandem mass spectrometric data–FAAH inhibitors activity relationships of some carbamic acid O-aryl esters 124
Sintesi e studi di relazione struttura–attività/selettività su O-bifenil-3-ilcarbammati disostituiti quali inibitori periferici dell’enzima FAAH 124
2-N-Acylaminoalkylindoles: Design and Quantitative Structure-Activity Relationship Studies Leading to MT2-Selective Antagonists. 123
FAAH and MGL Inhibitors. Design and Therapeutic Implications 123
URB602, a Monoacylglycerol Lipase Inhibitor, Protects from the Long-term Consequences of a Neonatal Hypoxic-ischemic Brain Injury in Rats 116
Structure-Activity Relationships of Alkylcarbamic Acid Aryl Esters, as Fatty Acid Amide Hydrolase Inhibitors 116
Seamus Heaney: una poesia del movimento 116
Synthesis of 1-(isoxazol-3-yl)triazene derivatives. Antimetastatic activity of 3,3-dimethyl-1-(5-methylisoxazol-3-yl)triazene. European Journal of Medicinal Chemistry (1996), 31(9), 735-740. 115
Correlation of the antimetastatic properties of aryltriazenes with their Electron Impact Ionization Mass Spectronomy 113
Methods, Compositions, and Other Compounds for Modulation of Monoacylglycerol Lipase Pain, and Stress-related Disorders 113
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 112
3D-QSAR study of carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 112
Synthesis and Biological Activity of Monoacylglycerol Lipase (MGL) Inhibitor URB602 and its Analogs 111
Design, Synthesis and SAR of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acids Amide Hydrolase Inhibitors 111
QSAR and molecular modelling investigations of a new series of alkyl carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 110
A linear relationship between MS/MS data and FAAH inhibitory activity of some carbamates 110
Synthesis of new C-6 alkylidene penicillin derivatives as beta-lactamase inhibitors 109
Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamates FAAH inhibitors 106
Insight into the mechanism of carbamate inactivation of FAAH by QM/MM modelling study 104
Mass Spectrometry and Pharmacology Activity: The Case of Carbamic Analogs 104
Inhibitors of lysosomal lipid amidase NAAA 103
Cannabinoids Modify Hippocampal Serotonergic Transmission 102
Correlation of the mutagenic properties of aryl- and heteroaryl-triazenes with their electron ionization induced fragmentation 100
Differences between direct cannabinoid agonists and FAAH inhibitors on antidepressant-like behavioural and serotonin-modulatory activity 99
Characterization of monoacylglycerol lipase (MGL) inhibitor URB602 98
The Collisional Behavior of ESI-Generated Protonated Molecules of Some Carbamate Bioisosters and its Relationship with their Biological Activity 98
Structure–Activity and Structure–Property Relationships of N-(2-Oxo-3-Oxetanyl)carbamic Acid Esters as N-Acylethanolamine-hydrolyzing Acid Amidase (NAAA) Inhibitors 97
Sintesi convergente di derivati triptofanici 2-sostituiti 94
Totale 15.878
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Categoria #
all - tutte 53.515
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 53.515
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.405 0 0 0 0 0 246 228 256 128 220 107 220
2020/20212.082 127 264 121 223 102 156 93 143 273 178 290 112
2021/20221.321 89 171 142 183 40 36 62 66 87 67 18 360
2022/20232.159 254 135 68 288 186 451 16 174 335 65 113 74
2023/2024569 70 44 51 74 36 120 22 36 10 46 14 46
2024/2025877 109 104 474 128 59 3 0 0 0 0 0 0
Totale 17.385