IRIS
TONTINI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 12.406
EU - Europa 9.068
AS - Asia 4.308
SA - Sud America 295
AF - Africa 53
OC - Oceania 22
Continente sconosciuto - Info sul continente non disponibili 14
Totale 26.166
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Nazione #
US - Stati Uniti d'America 12.264
GB - Regno Unito 2.434
CN - Cina 2.210
NL - Olanda 1.945
SG - Singapore 1.143
IT - Italia 1.113
UA - Ucraina 1.042
SE - Svezia 612
FI - Finlandia 412
RU - Federazione Russa 412
TR - Turchia 399
DE - Germania 397
IE - Irlanda 258
FR - Francia 232
BR - Brasile 216
VN - Vietnam 205
CA - Canada 98
IN - India 89
BE - Belgio 51
JP - Giappone 49
ES - Italia 34
KR - Corea 32
PL - Polonia 31
HK - Hong Kong 29
AR - Argentina 27
BD - Bangladesh 25
MX - Messico 23
IQ - Iraq 21
AT - Austria 18
AU - Australia 17
ID - Indonesia 17
RO - Romania 17
ZA - Sudafrica 17
KE - Kenya 13
EU - Europa 12
CL - Cile 11
CO - Colombia 11
LT - Lituania 11
SA - Arabia Saudita 11
IR - Iran 10
PK - Pakistan 10
VE - Venezuela 9
CH - Svizzera 8
AE - Emirati Arabi Uniti 7
JO - Giordania 6
PH - Filippine 6
PY - Paraguay 6
UZ - Uzbekistan 6
AL - Albania 5
EC - Ecuador 5
NZ - Nuova Zelanda 5
PE - Perù 5
AZ - Azerbaigian 4
ET - Etiopia 4
GR - Grecia 4
HN - Honduras 4
IL - Israele 4
LV - Lettonia 4
MA - Marocco 4
MY - Malesia 4
SM - San Marino 4
BG - Bulgaria 3
BZ - Belize 3
CR - Costa Rica 3
DO - Repubblica Dominicana 3
EG - Egitto 3
HU - Ungheria 3
JM - Giamaica 3
KG - Kirghizistan 3
PT - Portogallo 3
SI - Slovenia 3
TN - Tunisia 3
TW - Taiwan 3
AM - Armenia 2
FK - Isole Falkland (Malvinas) 2
KW - Kuwait 2
LA - Repubblica Popolare Democratica del Laos 2
LU - Lussemburgo 2
NO - Norvegia 2
RS - Serbia 2
SY - Repubblica araba siriana 2
TG - Togo 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AD - Andorra 1
BB - Barbados 1
BM - Bermuda 1
BO - Bolivia 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
CY - Cipro 1
DK - Danimarca 1
DZ - Algeria 1
EE - Estonia 1
GE - Georgia 1
GH - Ghana 1
GP - Guadalupe 1
HR - Croazia 1
IM - Isola di Man 1
LK - Sri Lanka 1
Totale 26.155
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Città #
Southend 2.214
Amsterdam 1.921
Dallas 1.271
Woodbridge 1.188
Ann Arbor 885
Houston 843
Jacksonville 831
Ashburn 797
Fairfield 775
Chandler 766
Singapore 592
San Jose 569
Nanjing 442
Cambridge 367
Beijing 331
Wilmington 318
Seattle 296
Izmir 287
Boardman 207
Dublin 202
Nanchang 178
Helsinki 163
San Mateo 146
New York 134
Princeton 119
Council Bluffs 106
Lauterbourg 105
Los Angeles 99
Hebei 92
Shenyang 91
Changsha 83
Tianjin 76
Ho Chi Minh City 75
Munich 69
Düsseldorf 68
Jiaxing 67
Santa Clara 63
Istanbul 61
Velikiy Novgorod 56
Brussels 50
Des Moines 50
Milan 49
Menlo Park 48
Shanghai 47
Buffalo 46
Hanoi 43
Kunming 43
Moscow 43
Toronto 40
Guangzhou 38
San Francisco 37
Bremen 36
London 34
Rome 33
Orem 31
San Diego 31
Jinan 30
Nuremberg 28
Seongnam 28
Urbino 28
Stockholm 27
Frankfurt am Main 26
Montreal 25
Warsaw 25
Hong Kong 24
Atlanta 23
Mülheim 23
Venice 23
Lanzhou 22
São Paulo 22
Denver 21
Ningbo 21
Tokyo 21
Zhengzhou 21
Changchun 20
Dearborn 20
Hangzhou 20
Chennai 19
Chicago 18
Brooklyn 17
Haikou 17
Ancona 16
Norwalk 15
Parma 15
Taizhou 15
Dong Ket 14
Florence 14
Manchester 14
Redwood City 14
Shenzhen 14
Vienna 14
Ankara 13
Cava De' Tirreni 13
Palermo 13
Phoenix 13
Turku 13
Auburn Hills 12
Elk Grove Village 12
Augusta 11
Johannesburg 11
Totale 18.477
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Nome #
1-Aminocyclopropane-1-carboxylic acid derivatives as ligands at the glicine-site of the NMDA receptor. 3.185
Inibitori dell’enzima NAAA (N-Acylethanolamine-Hydrolizing Acid Amidase) come nuovi agenti antinfiammatori 879
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis 868
1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES AS LIGANDS AT THE GLYCINE-BINDING SITE OF THE N-METHYL-D-ASPARTATE RECEPTOR 434
Pharmacokinetics, pharmacodynamics and safety studies on URB 937, a peripherally restricted fatty acid amide hydrolase inhibitor, in rats 372
Scoperta del primo inibitore dell’enzima idrolasi delle ammidi degli acidi grassi (FAAH) ad azione periferica 355
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 291
A New Synthesis of 2-Substituted DL-Tryptophan Derivatives 289
Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress 289
Sintesi e studi di relazione struttura-attività/stabilità di carbammati inibitori dell’enzima FAAH 286
A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo 286
3-(2-Carbamoylvinyl)-4,5-dimethylpyrrole-2-carboxylic acids as ligands at the NMDA glycine-binding site: a study on the 2-carbamoylvinyl chain modification 284
(E)-3-(2-(N-phenylcarbamoyl)vinyl)pyrrole-2-carboxylic acid derivatives. A novel class of glycine site antagonists. 281
An improved route to cycloalka[b]pyrrole 2-carboxylates 269
Structure–Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability 269
Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability 267
Identification of a Bioactive Impurity in a Commercial Sample of 6-Methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754) 258
2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists 247
Synthesis and Biological Evaluation of a γ-Cyclodextrin-based Formulation of the Anticancer Agent 5,6,11,12,17,18,23,24-Octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 246
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation 244
Application of a non-electrophysiological method to study binding affinity and efficacy of glicine analogs to the glicine site of the NMDA receptor-ion channel complex. 242
Anandamide suppressess pain initiation through a peripheral endocannabinoid mechanism 239
Modulation of Anxiety Through Blockade of Anandamide Hydrolysis 234
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 234
Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats 227
A practical and expeditious method for the preparation of the anticancer agent 5,6,11,12,17,18,23,24-octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 226
An endocannabinoid mechanism for stress-induced analgesia 222
(E)-3-[2-(Carbamoylvinyl)]pyrrol-2-carboxylic acid derivatives: A novel Class of glycine site Antagonists. 222
O-Biphenyl-3-yl Carbamates as Peripheral FAAH Inhibitors: Synthesis and Structure–Activity (SAR) Relationship Studies 219
Anthranilic acid based CCK1 antagonists: the 2-indole moiety may represent a "needle" according to the recent homonymous concept 218
N-acetiltriptamine 2,5-sostituite: sintesi e valutazione dell’attività biologica per i recettori melatoninergici MT1 e MT2 217
Peripherally Restricted FAAH Inhibitors 217
Synthesis and Structure–Activity Relationships of a Series of Pyrrole Cannabinoid Receptor Agonists 215
N-Acyl-5- and -2,5-substituted tryptamines: synthesis, activity and affinity for human mt1 and MT2 melatonin receptors 214
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 211
The Fatty Acid Amide Hydrolase Inhibitor URB597 (Cyclohexylcarbamic Acid 3’-Carbamoylbiphenyl-3-yl Ester) Reduces Neuropathic Pain after Oral Administration in Mice 210
2-N-Acylaminoalkylindoles: Design and Quantitative Structure-Activity Relationship Studies Leading to MT2-Selective Antagonists. 209
Sintesi e studi biologici preliminari su analoghi di URB937, il primo inibitore ad azione periferica dell'enzima FAAH 206
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 204
Endocannabinoids in the Treatment of Mood Disorders: Evidence from Animal Models 204
2 - Arachidonoylglycerol and anandamide are endocannabinoid mediators of stress - induced analgesia 201
SYNTHESIS, BINDING AFFINITY FOR THE MELATONIN RECEPTOR, AND EVALUATION OF THE BIOLOGICAL ACTIVITY OF NEW INDOLE-BASED MELATONIN ANALOGUES. 201
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 197
N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis, Structure–Activity and Structure–Property Relationships 195
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus 194
URB602 Inhibits Monoacylglycerol Lipase and Selectively Blocks 2-Arachidonoylglycerol Degradation in Intact Brain Slices 193
Modulation of anxiety through blockade of anandamide hydrolysis 193
Synthesis and Structure–Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors 191
Application of 3D-QSAR in the Rational Design of Receptor Ligands and Enzyme Inhibitors 189
α-Acylamino-β-lactones as a new class of N-acylethanolamine-hydrolyzing acid amidase (NAAA) inhibitors: synthesis and structure–activity relationships 188
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 187
Nitroisoxazoles by manganese(IV) oxide oxidation of nitro-4,5-dihydroisoxazoles. 186
Electron Impact Ionization and Fast Atom Bombardment Mass Spectrometry of Some 3,3-Dimethyl-1-(Isoxazol-3-yl)-triazenes. A New Class of Potential Anticancer Agents. 186
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice 186
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 186
Synthesis and Structure–Activity Relationship Studies of O-Biphenyl-3-yl Carbamates as Peripherally Restricted Fatty Acid Amide Hydrolase Inhibitors 185
Synthesis and Structure-Activity/Stability Relationships of Carbamate Inhibitors of the FAAH Enzyme 183
The CB1 Antagonist/CB2 Agonist URB447 Confers Neuroprotection after Neonatal Hypoxia-ischemia 183
The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues 183
Pharmacological Profile of the Selective FAAH Inhibitor KDS-4103 (URB597) 182
ANTIMETASTATIC ACTION OF A NEW ANALOG OF DACARBAZINE IN MICE BEARING LEWIS LUNG CARCINOMA 180
N-alchil-O-arilcarbammati come inibitori delle idrolasi delle ammidi degli acidi grassi (FAAH): aspetti meccanicistici 179
Sintesi e studi di relazione struttura–attività/selettività su O-bifenil-3-ilcarbammati disostituiti quali inibitori periferici dell’enzima FAAH 179
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 179
Synthesis and biological evaluation of 6-bromo-6-substituted penicillanic acid derivatives as beta-lactamase inhibitors. 178
A linear relationship between MS/MS data and FAAH inhibitory activity of some carbamates 174
Identification of a Bioactive Impurity Present in a Sample of URB754 173
Selective inhibition of 2 - AG hydrolysis enhances endocannabinoid signaling in the hippocampus 171
Mimosine induces apoptosis in the HL60 human tumor cell line. 170
Short synthesis of tryptophan and β -carboline derivatives by reaction of indoles with N-(diphenylmethylene)-α ,β -didehydroamino acid esters 168
3D-QSAR study of carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 165
Characterization of the Fatty Acid Amide Hydrolase Inhibitor Cyclohexyl Carbamic Acid 3'-Carbamoyl-biphenyl-3-yl Ester (URB597): Effects on Anandamide and Oleoylethanolamide Deactivation 163
Design, SAR and Biological Activity of a New Class of FAAH Inhibitors: Cyclohexyl Carbamic Acid Biphenyl-3-yl Esters 158
Antinociceptive effects of the brain-impermeant fatty-acid amide hydrolase inhibitor URB937 158
Synthesis and pharmacological characterization of URB447, a new cannabinoid receptor neutral antagonist 157
Rotation about the N2-N3 bond in 3,3-dimethyl-1-(isoxazol-3-yl)triazene 155
Tandem mass spectrometric data–FAAH inhibitors activity relationships of some carbamic acid O-aryl esters 152
Inhibitors of lysosomal lipid amidase NAAA 152
URB602, a Monoacylglycerol Lipase Inhibitor, Protects from the Long-term Consequences of a Neonatal Hypoxic-ischemic Brain Injury in Rats 146
QSAR and molecular modelling investigations of a new series of alkyl carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 146
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 145
Structure-Activity Relationships of Alkylcarbamic Acid Aryl Esters, as Fatty Acid Amide Hydrolase Inhibitors 145
Design, Synthesis and SAR of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acids Amide Hydrolase Inhibitors 145
Synthesis of new C-6 alkylidene penicillin derivatives as beta-lactamase inhibitors 144
FAAH and MGL Inhibitors. Design and Therapeutic Implications 143
Synthesis of 1-(isoxazol-3-yl)triazene derivatives. Antimetastatic activity of 3,3-dimethyl-1-(5-methylisoxazol-3-yl)triazene. European Journal of Medicinal Chemistry (1996), 31(9), 735-740. 142
Correlation of the antimetastatic properties of aryltriazenes with their Electron Impact Ionization Mass Spectronomy 141
Methods, Compositions, and Other Compounds for Modulation of Monoacylglycerol Lipase Pain, and Stress-related Disorders 140
Cannabinoids Modify Hippocampal Serotonergic Transmission 139
Seamus Heaney: una poesia del movimento 138
Synthesis and Pharmacological Characterization of Potent and Selective Inhibitors of Fatty Acid Amidohydrolase (FAAH) 138
Structure–Activity and Structure–Property Relationships of N-(2-Oxo-3-Oxetanyl)carbamic Acid Esters as N-Acylethanolamine-hydrolyzing Acid Amidase (NAAA) Inhibitors 134
Synthesis, QSAR and Pharmacological Evaluation of Alkylcarbamic Acid Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: A Novel Approach to Antianxiety and Analgesic Agents 132
Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamates FAAH inhibitors 132
Insight into the mechanism of carbamate inactivation of FAAH by QM/MM modelling study 130
Mass Spectrometry and Pharmacology Activity: The Case of Carbamic Analogs 129
Synthesis and Biological Activity of Monoacylglycerol Lipase (MGL) Inhibitor URB602 and its Analogs 129
Correlation of the mutagenic properties of aryl- and heteroaryl-triazenes with their electron ionization induced fragmentation 128
Reactivity, metabolic stability and interaction at the catalytic site for carbamate inhibitors of FAAH 128
Differences between direct cannabinoid agonists and FAAH inhibitors on antidepressant-like behavioural and serotonin-modulatory activity 128
Totale 24.111
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Categoria #
all - tutte 79.522
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 79.522
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.321 89 171 142 183 40 36 62 66 87 67 18 360
2022/20232.159 254 135 68 288 186 451 16 174 335 65 113 74
2023/2024569 70 44 51 74 36 120 22 36 10 46 14 46
2024/20251.891 109 104 474 128 59 146 216 94 156 131 137 137
2025/20267.230 381 698 1.214 773 357 359 571 138 2.102 305 210 122
2026/2027679 679 0 0 0 0 0 0 0 0 0 0 0
Totale 26.308