IRIS
TONTINI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 11.370
EU - Europa 9.042
AS - Asia 4.257
SA - Sud America 289
AF - Africa 53
OC - Oceania 22
Continente sconosciuto - Info sul continente non disponibili 14
Totale 25.047
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Nazione #
US - Stati Uniti d'America 11.245
GB - Regno Unito 2.434
CN - Cina 2.189
NL - Olanda 1.945
SG - Singapore 1.119
IT - Italia 1.092
UA - Ucraina 1.042
SE - Svezia 612
FI - Finlandia 412
RU - Federazione Russa 412
TR - Turchia 399
DE - Germania 397
IE - Irlanda 257
FR - Francia 231
BR - Brasile 213
VN - Vietnam 205
CA - Canada 89
IN - India 89
BE - Belgio 51
JP - Giappone 48
ES - Italia 33
KR - Corea 32
PL - Polonia 31
AR - Argentina 26
HK - Hong Kong 25
BD - Bangladesh 24
MX - Messico 22
IQ - Iraq 21
AT - Austria 18
AU - Australia 17
ID - Indonesia 17
ZA - Sudafrica 17
RO - Romania 16
KE - Kenya 13
EU - Europa 12
CL - Cile 11
LT - Lituania 11
SA - Arabia Saudita 11
CO - Colombia 10
IR - Iran 10
PK - Pakistan 10
VE - Venezuela 9
CH - Svizzera 8
AE - Emirati Arabi Uniti 7
JO - Giordania 6
PH - Filippine 6
PY - Paraguay 6
UZ - Uzbekistan 6
AL - Albania 5
NZ - Nuova Zelanda 5
PE - Perù 5
AZ - Azerbaigian 4
EC - Ecuador 4
ET - Etiopia 4
GR - Grecia 4
IL - Israele 4
LV - Lettonia 4
MA - Marocco 4
MY - Malesia 4
SM - San Marino 4
BG - Bulgaria 3
DO - Repubblica Dominicana 3
EG - Egitto 3
HU - Ungheria 3
JM - Giamaica 3
KG - Kirghizistan 3
PT - Portogallo 3
SI - Slovenia 3
TN - Tunisia 3
TW - Taiwan 3
AM - Armenia 2
BZ - Belize 2
CR - Costa Rica 2
FK - Isole Falkland (Malvinas) 2
HN - Honduras 2
KW - Kuwait 2
LA - Repubblica Popolare Democratica del Laos 2
LU - Lussemburgo 2
NO - Norvegia 2
RS - Serbia 2
SY - Repubblica araba siriana 2
TG - Togo 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BB - Barbados 1
BO - Bolivia 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
CY - Cipro 1
DK - Danimarca 1
DZ - Algeria 1
EE - Estonia 1
GE - Georgia 1
GH - Ghana 1
HR - Croazia 1
IM - Isola di Man 1
LK - Sri Lanka 1
NG - Nigeria 1
NP - Nepal 1
OM - Oman 1
Totale 25.040
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Città #
Southend 2.214
Amsterdam 1.921
Dallas 1.262
Woodbridge 1.188
Ann Arbor 884
Houston 840
Jacksonville 829
Ashburn 779
Fairfield 775
Chandler 766
Singapore 590
San Jose 461
Nanjing 442
Cambridge 367
Beijing 320
Wilmington 318
Seattle 295
Izmir 287
Dublin 201
Boardman 189
Nanchang 178
Helsinki 163
San Mateo 146
New York 126
Princeton 119
Lauterbourg 105
Los Angeles 95
Hebei 92
Shenyang 91
Changsha 83
Tianjin 76
Ho Chi Minh City 75
Munich 69
Düsseldorf 68
Jiaxing 67
Istanbul 61
Velikiy Novgorod 56
Brussels 50
Des Moines 50
Santa Clara 50
Council Bluffs 48
Menlo Park 48
Shanghai 47
Milan 46
Hanoi 43
Kunming 43
Moscow 43
Guangzhou 38
Toronto 37
Bremen 36
Buffalo 35
San Francisco 35
London 34
Rome 31
San Diego 31
Jinan 30
Nuremberg 28
Orem 28
Seongnam 28
Urbino 28
Stockholm 27
Frankfurt am Main 26
Warsaw 25
Mülheim 23
Venice 23
Lanzhou 22
Montreal 22
São Paulo 22
Ningbo 21
Tokyo 21
Zhengzhou 21
Changchun 20
Dearborn 20
Hong Kong 20
Chennai 19
Denver 19
Hangzhou 19
Haikou 17
Ancona 16
Chicago 16
Parma 15
Taizhou 15
Brooklyn 14
Dong Ket 14
Florence 14
Manchester 14
Norwalk 14
Redwood City 14
Shenzhen 14
Vienna 14
Ankara 13
Cava De' Tirreni 13
Palermo 13
Turku 13
Auburn Hills 12
Elk Grove Village 12
Augusta 11
Johannesburg 11
Mumbai 11
Phoenix 11
Totale 18.166
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Nome #
1-Aminocyclopropane-1-carboxylic acid derivatives as ligands at the glicine-site of the NMDA receptor. 3.172
Inibitori dell’enzima NAAA (N-Acylethanolamine-Hydrolizing Acid Amidase) come nuovi agenti antinfiammatori 865
1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES AS LIGANDS AT THE GLYCINE-BINDING SITE OF THE N-METHYL-D-ASPARTATE RECEPTOR 429
Pharmacokinetics, pharmacodynamics and safety studies on URB 937, a peripherally restricted fatty acid amide hydrolase inhibitor, in rats 369
Scoperta del primo inibitore dell’enzima idrolasi delle ammidi degli acidi grassi (FAAH) ad azione periferica 350
A New Synthesis of 2-Substituted DL-Tryptophan Derivatives 285
Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress 281
A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo 277
(E)-3-(2-(N-phenylcarbamoyl)vinyl)pyrrole-2-carboxylic acid derivatives. A novel class of glycine site antagonists. 275
Sintesi e studi di relazione struttura-attività/stabilità di carbammati inibitori dell’enzima FAAH 275
3-(2-Carbamoylvinyl)-4,5-dimethylpyrrole-2-carboxylic acids as ligands at the NMDA glycine-binding site: a study on the 2-carbamoylvinyl chain modification 274
Structure–Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability 268
An improved route to cycloalka[b]pyrrole 2-carboxylates 262
Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability 261
Identification of a Bioactive Impurity in a Commercial Sample of 6-Methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754) 251
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis 242
Synthesis and Biological Evaluation of a γ-Cyclodextrin-based Formulation of the Anticancer Agent 5,6,11,12,17,18,23,24-Octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 242
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation 240
2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists 240
Application of a non-electrophysiological method to study binding affinity and efficacy of glicine analogs to the glicine site of the NMDA receptor-ion channel complex. 233
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 233
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 232
Modulation of Anxiety Through Blockade of Anandamide Hydrolysis 230
Anandamide suppressess pain initiation through a peripheral endocannabinoid mechanism 229
Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats 227
A practical and expeditious method for the preparation of the anticancer agent 5,6,11,12,17,18,23,24-octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 223
An endocannabinoid mechanism for stress-induced analgesia 219
(E)-3-[2-(Carbamoylvinyl)]pyrrol-2-carboxylic acid derivatives: A novel Class of glycine site Antagonists. 218
Anthranilic acid based CCK1 antagonists: the 2-indole moiety may represent a "needle" according to the recent homonymous concept 214
O-Biphenyl-3-yl Carbamates as Peripheral FAAH Inhibitors: Synthesis and Structure–Activity (SAR) Relationship Studies 214
Peripherally Restricted FAAH Inhibitors 214
Synthesis and Structure–Activity Relationships of a Series of Pyrrole Cannabinoid Receptor Agonists 211
N-acetiltriptamine 2,5-sostituite: sintesi e valutazione dell’attività biologica per i recettori melatoninergici MT1 e MT2 210
N-Acyl-5- and -2,5-substituted tryptamines: synthesis, activity and affinity for human mt1 and MT2 melatonin receptors 208
2-N-Acylaminoalkylindoles: Design and Quantitative Structure-Activity Relationship Studies Leading to MT2-Selective Antagonists. 206
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 203
Sintesi e studi biologici preliminari su analoghi di URB937, il primo inibitore ad azione periferica dell'enzima FAAH 202
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 201
Endocannabinoids in the Treatment of Mood Disorders: Evidence from Animal Models 201
The Fatty Acid Amide Hydrolase Inhibitor URB597 (Cyclohexylcarbamic Acid 3’-Carbamoylbiphenyl-3-yl Ester) Reduces Neuropathic Pain after Oral Administration in Mice 200
2 - Arachidonoylglycerol and anandamide are endocannabinoid mediators of stress - induced analgesia 198
SYNTHESIS, BINDING AFFINITY FOR THE MELATONIN RECEPTOR, AND EVALUATION OF THE BIOLOGICAL ACTIVITY OF NEW INDOLE-BASED MELATONIN ANALOGUES. 196
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 195
Modulation of anxiety through blockade of anandamide hydrolysis 193
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus 192
URB602 Inhibits Monoacylglycerol Lipase and Selectively Blocks 2-Arachidonoylglycerol Degradation in Intact Brain Slices 191
N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis, Structure–Activity and Structure–Property Relationships 189
Application of 3D-QSAR in the Rational Design of Receptor Ligands and Enzyme Inhibitors 188
Synthesis and Structure–Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors 187
α-Acylamino-β-lactones as a new class of N-acylethanolamine-hydrolyzing acid amidase (NAAA) inhibitors: synthesis and structure–activity relationships 185
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 185
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 185
Synthesis and Structure–Activity Relationship Studies of O-Biphenyl-3-yl Carbamates as Peripherally Restricted Fatty Acid Amide Hydrolase Inhibitors 185
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice 184
Nitroisoxazoles by manganese(IV) oxide oxidation of nitro-4,5-dihydroisoxazoles. 183
Electron Impact Ionization and Fast Atom Bombardment Mass Spectrometry of Some 3,3-Dimethyl-1-(Isoxazol-3-yl)-triazenes. A New Class of Potential Anticancer Agents. 183
The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues 182
The CB1 Antagonist/CB2 Agonist URB447 Confers Neuroprotection after Neonatal Hypoxia-ischemia 181
Pharmacological Profile of the Selective FAAH Inhibitor KDS-4103 (URB597) 179
ANTIMETASTATIC ACTION OF A NEW ANALOG OF DACARBAZINE IN MICE BEARING LEWIS LUNG CARCINOMA 178
N-alchil-O-arilcarbammati come inibitori delle idrolasi delle ammidi degli acidi grassi (FAAH): aspetti meccanicistici 178
Synthesis and Structure-Activity/Stability Relationships of Carbamate Inhibitors of the FAAH Enzyme 178
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 177
Sintesi e studi di relazione struttura–attività/selettività su O-bifenil-3-ilcarbammati disostituiti quali inibitori periferici dell’enzima FAAH 175
Synthesis and biological evaluation of 6-bromo-6-substituted penicillanic acid derivatives as beta-lactamase inhibitors. 174
Selective inhibition of 2 - AG hydrolysis enhances endocannabinoid signaling in the hippocampus 171
Identification of a Bioactive Impurity Present in a Sample of URB754 171
A linear relationship between MS/MS data and FAAH inhibitory activity of some carbamates 170
Mimosine induces apoptosis in the HL60 human tumor cell line. 169
Short synthesis of tryptophan and β -carboline derivatives by reaction of indoles with N-(diphenylmethylene)-α ,β -didehydroamino acid esters 164
3D-QSAR study of carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 163
Characterization of the Fatty Acid Amide Hydrolase Inhibitor Cyclohexyl Carbamic Acid 3'-Carbamoyl-biphenyl-3-yl Ester (URB597): Effects on Anandamide and Oleoylethanolamide Deactivation 157
Synthesis and pharmacological characterization of URB447, a new cannabinoid receptor neutral antagonist 157
Design, SAR and Biological Activity of a New Class of FAAH Inhibitors: Cyclohexyl Carbamic Acid Biphenyl-3-yl Esters 154
Antinociceptive effects of the brain-impermeant fatty-acid amide hydrolase inhibitor URB937 153
Rotation about the N2-N3 bond in 3,3-dimethyl-1-(isoxazol-3-yl)triazene 152
Inhibitors of lysosomal lipid amidase NAAA 151
Tandem mass spectrometric data–FAAH inhibitors activity relationships of some carbamic acid O-aryl esters 146
URB602, a Monoacylglycerol Lipase Inhibitor, Protects from the Long-term Consequences of a Neonatal Hypoxic-ischemic Brain Injury in Rats 145
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 144
QSAR and molecular modelling investigations of a new series of alkyl carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 142
Structure-Activity Relationships of Alkylcarbamic Acid Aryl Esters, as Fatty Acid Amide Hydrolase Inhibitors 142
Synthesis of new C-6 alkylidene penicillin derivatives as beta-lactamase inhibitors 142
FAAH and MGL Inhibitors. Design and Therapeutic Implications 142
Synthesis of 1-(isoxazol-3-yl)triazene derivatives. Antimetastatic activity of 3,3-dimethyl-1-(5-methylisoxazol-3-yl)triazene. European Journal of Medicinal Chemistry (1996), 31(9), 735-740. 140
Correlation of the antimetastatic properties of aryltriazenes with their Electron Impact Ionization Mass Spectronomy 139
Cannabinoids Modify Hippocampal Serotonergic Transmission 138
Methods, Compositions, and Other Compounds for Modulation of Monoacylglycerol Lipase Pain, and Stress-related Disorders 137
Design, Synthesis and SAR of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acids Amide Hydrolase Inhibitors 136
Seamus Heaney: una poesia del movimento 134
Synthesis and Pharmacological Characterization of Potent and Selective Inhibitors of Fatty Acid Amidohydrolase (FAAH) 134
Structure–Activity and Structure–Property Relationships of N-(2-Oxo-3-Oxetanyl)carbamic Acid Esters as N-Acylethanolamine-hydrolyzing Acid Amidase (NAAA) Inhibitors 132
Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamates FAAH inhibitors 130
Insight into the mechanism of carbamate inactivation of FAAH by QM/MM modelling study 129
Correlation of the mutagenic properties of aryl- and heteroaryl-triazenes with their electron ionization induced fragmentation 128
Mass Spectrometry and Pharmacology Activity: The Case of Carbamic Analogs 127
Synthesis and Biological Activity of Monoacylglycerol Lipase (MGL) Inhibitor URB602 and its Analogs 127
Differences between direct cannabinoid agonists and FAAH inhibitors on antidepressant-like behavioural and serotonin-modulatory activity 127
Synthesis, QSAR and Pharmacological Evaluation of Alkylcarbamic Acid Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: A Novel Approach to Antianxiety and Analgesic Agents 125
Esteri bifenil-3-ilici dell'acido cicloesilcarbammico quali inibitori dell'enzima FAAH: sintesi, QSAR e modellistica molecolare 124
Totale 23.049
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Categoria #
all - tutte 75.167
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 75.167
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021580 0 0 0 0 0 0 0 0 0 178 290 112
2021/20221.321 89 171 142 183 40 36 62 66 87 67 18 360
2022/20232.159 254 135 68 288 186 451 16 174 335 65 113 74
2023/2024569 70 44 51 74 36 120 22 36 10 46 14 46
2024/20251.891 109 104 474 128 59 146 216 94 156 131 137 137
2025/20266.790 381 698 1.214 773 357 359 571 138 2.102 197 0 0
Totale 25.189