IRIS
TONTINI, ANDREA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 10.754
EU - Europa 6.908
AS - Asia 3.865
SA - Sud America 260
AF - Africa 36
OC - Oceania 21
Continente sconosciuto - Info sul continente non disponibili 13
Totale 21.857
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 10.645
GB - Regno Unito 2.425
CN - Cina 2.145
IT - Italia 1.058
UA - Ucraina 1.038
SG - Singapore 881
SE - Svezia 611
FI - Finlandia 394
TR - Turchia 393
DE - Germania 385
RU - Federazione Russa 335
IE - Irlanda 254
BR - Brasile 198
VN - Vietnam 160
FR - Francia 129
CA - Canada 83
NL - Olanda 79
IN - India 77
BE - Belgio 51
JP - Giappone 43
KR - Corea 32
ES - Italia 30
PL - Polonia 30
AR - Argentina 25
BD - Bangladesh 19
HK - Hong Kong 19
AT - Austria 18
AU - Australia 16
RO - Romania 16
MX - Messico 15
ID - Indonesia 14
EU - Europa 12
ZA - Sudafrica 12
LT - Lituania 11
SA - Arabia Saudita 11
CL - Cile 10
IQ - Iraq 10
KE - Kenya 10
IR - Iran 9
CH - Svizzera 7
CO - Colombia 7
PK - Pakistan 7
AE - Emirati Arabi Uniti 6
AL - Albania 5
NZ - Nuova Zelanda 5
PE - Perù 5
PH - Filippine 5
UZ - Uzbekistan 5
IL - Israele 4
JO - Giordania 4
PY - Paraguay 4
SM - San Marino 4
VE - Venezuela 4
AZ - Azerbaigian 3
BG - Bulgaria 3
EG - Egitto 3
GR - Grecia 3
HU - Ungheria 3
KG - Kirghizistan 3
LV - Lettonia 3
MA - Marocco 3
PT - Portogallo 3
SI - Slovenia 3
TW - Taiwan 3
AM - Armenia 2
BZ - Belize 2
CR - Costa Rica 2
DO - Repubblica Dominicana 2
EC - Ecuador 2
ET - Etiopia 2
FK - Isole Falkland (Malvinas) 2
HN - Honduras 2
KW - Kuwait 2
LA - Repubblica Popolare Democratica del Laos 2
LU - Lussemburgo 2
NO - Norvegia 2
TG - Togo 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BB - Barbados 1
BO - Bolivia 1
BY - Bielorussia 1
CY - Cipro 1
DK - Danimarca 1
DZ - Algeria 1
EE - Estonia 1
HR - Croazia 1
IM - Isola di Man 1
JM - Giamaica 1
LK - Sri Lanka 1
MY - Malesia 1
NP - Nepal 1
PA - Panama 1
PS - Palestinian Territory 1
RS - Serbia 1
SC - Seychelles 1
SY - Repubblica araba siriana 1
UG - Uganda 1
ZW - Zimbabwe 1
Totale 21.857
Salva come PNG Salva come JPEG
Città #
Southend 2.214
Dallas 1.261
Woodbridge 1.188
Ann Arbor 884
Houston 840
Jacksonville 829
Fairfield 775
Chandler 766
Ashburn 712
Nanjing 442
Singapore 385
Cambridge 367
Wilmington 318
Beijing 315
Seattle 295
Izmir 287
Dublin 199
Boardman 188
Nanchang 178
San Mateo 146
Helsinki 145
New York 121
Princeton 119
Hebei 92
Shenyang 91
Los Angeles 90
Changsha 83
Tianjin 76
Munich 69
Düsseldorf 68
Jiaxing 67
Ho Chi Minh City 60
Istanbul 59
Velikiy Novgorod 56
Amsterdam 55
Brussels 50
Des Moines 50
Menlo Park 48
Shanghai 47
Santa Clara 46
Kunming 43
Moscow 43
Council Bluffs 41
Milan 41
Guangzhou 37
Bremen 36
San Francisco 35
Toronto 35
Buffalo 32
Hanoi 31
London 31
San Diego 31
Jinan 29
Seongnam 28
Urbino 28
Nuremberg 27
Rome 27
Stockholm 26
Warsaw 25
Mülheim 23
Venice 23
Lanzhou 22
São Paulo 22
Ningbo 21
Zhengzhou 21
Changchun 20
Dearborn 20
Denver 19
Hangzhou 19
Montreal 19
Orem 19
Frankfurt am Main 17
Haikou 17
Ancona 16
Tokyo 16
Chicago 15
Parma 15
Taizhou 15
Brooklyn 14
Chennai 14
Dong Ket 14
Hong Kong 14
Norwalk 14
Redwood City 14
Shenzhen 14
Vienna 14
Ankara 13
Cava De' Tirreni 13
Palermo 13
Turku 13
Auburn Hills 12
Florence 12
Augusta 11
Phoenix 11
Hefei 10
Johannesburg 10
Manchester 10
Mumbai 10
Napoli 10
Padova 10
Totale 15.336
Salva come PNG Salva come JPEG
Nome #
1-Aminocyclopropane-1-carboxylic acid derivatives as ligands at the glicine-site of the NMDA receptor. 1.282
Inibitori dell’enzima NAAA (N-Acylethanolamine-Hydrolizing Acid Amidase) come nuovi agenti antinfiammatori 838
1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES AS LIGANDS AT THE GLYCINE-BINDING SITE OF THE N-METHYL-D-ASPARTATE RECEPTOR 416
Pharmacokinetics, pharmacodynamics and safety studies on URB 937, a peripherally restricted fatty acid amide hydrolase inhibitor, in rats 360
Scoperta del primo inibitore dell’enzima idrolasi delle ammidi degli acidi grassi (FAAH) ad azione periferica 328
A New Synthesis of 2-Substituted DL-Tryptophan Derivatives 272
Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress 268
A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo 266
(E)-3-(2-(N-phenylcarbamoyl)vinyl)pyrrole-2-carboxylic acid derivatives. A novel class of glycine site antagonists. 260
3-(2-Carbamoylvinyl)-4,5-dimethylpyrrole-2-carboxylic acids as ligands at the NMDA glycine-binding site: a study on the 2-carbamoylvinyl chain modification 260
Structure–Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability 257
Sintesi e studi di relazione struttura-attività/stabilità di carbammati inibitori dell’enzima FAAH 255
An improved route to cycloalka[b]pyrrole 2-carboxylates 245
Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability 242
Identification of a Bioactive Impurity in a Commercial Sample of 6-Methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754) 237
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis 230
Synthesis and Biological Evaluation of a γ-Cyclodextrin-based Formulation of the Anticancer Agent 5,6,11,12,17,18,23,24-Octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 230
2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists 225
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation 224
Modulation of Anxiety Through Blockade of Anandamide Hydrolysis 222
Application of a non-electrophysiological method to study binding affinity and efficacy of glicine analogs to the glicine site of the NMDA receptor-ion channel complex. 219
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 218
Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats 217
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 215
An endocannabinoid mechanism for stress-induced analgesia 209
A practical and expeditious method for the preparation of the anticancer agent 5,6,11,12,17,18,23,24-octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 209
Synthesis and Structure–Activity Relationships of a Series of Pyrrole Cannabinoid Receptor Agonists 205
Anandamide suppressess pain initiation through a peripheral endocannabinoid mechanism 205
Anthranilic acid based CCK1 antagonists: the 2-indole moiety may represent a "needle" according to the recent homonymous concept 204
(E)-3-[2-(Carbamoylvinyl)]pyrrol-2-carboxylic acid derivatives: A novel Class of glycine site Antagonists. 203
O-Biphenyl-3-yl Carbamates as Peripheral FAAH Inhibitors: Synthesis and Structure–Activity (SAR) Relationship Studies 200
Peripherally Restricted FAAH Inhibitors 198
N-acetiltriptamine 2,5-sostituite: sintesi e valutazione dell’attività biologica per i recettori melatoninergici MT1 e MT2 197
Endocannabinoids in the Treatment of Mood Disorders: Evidence from Animal Models 195
N-Acyl-5- and -2,5-substituted tryptamines: synthesis, activity and affinity for human mt1 and MT2 melatonin receptors 194
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 194
2-N-Acylaminoalkylindoles: Design and Quantitative Structure-Activity Relationship Studies Leading to MT2-Selective Antagonists. 192
SYNTHESIS, BINDING AFFINITY FOR THE MELATONIN RECEPTOR, AND EVALUATION OF THE BIOLOGICAL ACTIVITY OF NEW INDOLE-BASED MELATONIN ANALOGUES. 192
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 190
The Fatty Acid Amide Hydrolase Inhibitor URB597 (Cyclohexylcarbamic Acid 3’-Carbamoylbiphenyl-3-yl Ester) Reduces Neuropathic Pain after Oral Administration in Mice 188
Sintesi e studi biologici preliminari su analoghi di URB937, il primo inibitore ad azione periferica dell'enzima FAAH 187
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 186
2 - Arachidonoylglycerol and anandamide are endocannabinoid mediators of stress - induced analgesia 184
Application of 3D-QSAR in the Rational Design of Receptor Ligands and Enzyme Inhibitors 184
URB602 Inhibits Monoacylglycerol Lipase and Selectively Blocks 2-Arachidonoylglycerol Degradation in Intact Brain Slices 181
Modulation of anxiety through blockade of anandamide hydrolysis 181
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus 180
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 180
Electron Impact Ionization and Fast Atom Bombardment Mass Spectrometry of Some 3,3-Dimethyl-1-(Isoxazol-3-yl)-triazenes. A New Class of Potential Anticancer Agents. 177
N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis, Structure–Activity and Structure–Property Relationships 176
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice 175
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 175
Synthesis and Structure–Activity Relationship Studies of O-Biphenyl-3-yl Carbamates as Peripherally Restricted Fatty Acid Amide Hydrolase Inhibitors 175
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 175
Synthesis and Structure–Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors 174
Nitroisoxazoles by manganese(IV) oxide oxidation of nitro-4,5-dihydroisoxazoles. 172
The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues 172
Pharmacological Profile of the Selective FAAH Inhibitor KDS-4103 (URB597) 170
α-Acylamino-β-lactones as a new class of N-acylethanolamine-hydrolyzing acid amidase (NAAA) inhibitors: synthesis and structure–activity relationships 170
N-alchil-O-arilcarbammati come inibitori delle idrolasi delle ammidi degli acidi grassi (FAAH): aspetti meccanicistici 169
ANTIMETASTATIC ACTION OF A NEW ANALOG OF DACARBAZINE IN MICE BEARING LEWIS LUNG CARCINOMA 168
Synthesis and Structure-Activity/Stability Relationships of Carbamate Inhibitors of the FAAH Enzyme 167
Selective inhibition of 2 - AG hydrolysis enhances endocannabinoid signaling in the hippocampus 165
The CB1 Antagonist/CB2 Agonist URB447 Confers Neuroprotection after Neonatal Hypoxia-ischemia 164
Mimosine induces apoptosis in the HL60 human tumor cell line. 164
Synthesis and biological evaluation of 6-bromo-6-substituted penicillanic acid derivatives as beta-lactamase inhibitors. 160
Identification of a Bioactive Impurity Present in a Sample of URB754 160
A linear relationship between MS/MS data and FAAH inhibitory activity of some carbamates 160
Sintesi e studi di relazione struttura–attività/selettività su O-bifenil-3-ilcarbammati disostituiti quali inibitori periferici dell’enzima FAAH 157
Short synthesis of tryptophan and β -carboline derivatives by reaction of indoles with N-(diphenylmethylene)-α ,β -didehydroamino acid esters 155
3D-QSAR study of carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 149
Characterization of the Fatty Acid Amide Hydrolase Inhibitor Cyclohexyl Carbamic Acid 3'-Carbamoyl-biphenyl-3-yl Ester (URB597): Effects on Anandamide and Oleoylethanolamide Deactivation 148
Design, SAR and Biological Activity of a New Class of FAAH Inhibitors: Cyclohexyl Carbamic Acid Biphenyl-3-yl Esters 147
Rotation about the N2-N3 bond in 3,3-dimethyl-1-(isoxazol-3-yl)triazene 146
Synthesis and pharmacological characterization of URB447, a new cannabinoid receptor neutral antagonist 145
Antinociceptive effects of the brain-impermeant fatty-acid amide hydrolase inhibitor URB937 145
Tandem mass spectrometric data–FAAH inhibitors activity relationships of some carbamic acid O-aryl esters 140
Inhibitors of lysosomal lipid amidase NAAA 137
URB602, a Monoacylglycerol Lipase Inhibitor, Protects from the Long-term Consequences of a Neonatal Hypoxic-ischemic Brain Injury in Rats 136
Synthesis of 1-(isoxazol-3-yl)triazene derivatives. Antimetastatic activity of 3,3-dimethyl-1-(5-methylisoxazol-3-yl)triazene. European Journal of Medicinal Chemistry (1996), 31(9), 735-740. 135
Correlation of the antimetastatic properties of aryltriazenes with their Electron Impact Ionization Mass Spectronomy 134
QSAR and molecular modelling investigations of a new series of alkyl carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 134
FAAH and MGL Inhibitors. Design and Therapeutic Implications 134
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 132
Cannabinoids Modify Hippocampal Serotonergic Transmission 130
Structure-Activity Relationships of Alkylcarbamic Acid Aryl Esters, as Fatty Acid Amide Hydrolase Inhibitors 130
Seamus Heaney: una poesia del movimento 130
Synthesis of new C-6 alkylidene penicillin derivatives as beta-lactamase inhibitors 130
Methods, Compositions, and Other Compounds for Modulation of Monoacylglycerol Lipase Pain, and Stress-related Disorders 128
Synthesis and Pharmacological Characterization of Potent and Selective Inhibitors of Fatty Acid Amidohydrolase (FAAH) 128
Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamates FAAH inhibitors 125
Design, Synthesis and SAR of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acids Amide Hydrolase Inhibitors 123
Synthesis and Biological Activity of Monoacylglycerol Lipase (MGL) Inhibitor URB602 and its Analogs 122
Insight into the mechanism of carbamate inactivation of FAAH by QM/MM modelling study 121
Correlation of the mutagenic properties of aryl- and heteroaryl-triazenes with their electron ionization induced fragmentation 118
Mass Spectrometry and Pharmacology Activity: The Case of Carbamic Analogs 118
Synthesis, QSAR and Pharmacological Evaluation of Alkylcarbamic Acid Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: A Novel Approach to Antianxiety and Analgesic Agents 118
Structure–Activity and Structure–Property Relationships of N-(2-Oxo-3-Oxetanyl)carbamic Acid Esters as N-Acylethanolamine-hydrolyzing Acid Amidase (NAAA) Inhibitors 116
Differences between direct cannabinoid agonists and FAAH inhibitors on antidepressant-like behavioural and serotonin-modulatory activity 116
Esteri bifenil-3-ilici dell'acido cicloesilcarbammico quali inibitori dell'enzima FAAH: sintesi, QSAR e modellistica molecolare 114
Totale 20.053
Salva come PNG Salva come JPEG
Categoria #
all - tutte 70.633
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 70.633
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.245 0 0 0 0 0 156 93 143 273 178 290 112
2021/20221.321 89 171 142 183 40 36 62 66 87 67 18 360
2022/20232.159 254 135 68 288 186 451 16 174 335 65 113 74
2023/2024569 70 44 51 74 36 120 22 36 10 46 14 46
2024/20251.891 109 104 474 128 59 146 216 94 156 131 137 137
2025/20263.600 381 698 1.214 773 357 177 0 0 0 0 0 0
Totale 21.999