| Nome |
# |
|
Iridium-Catalyzed Direct Synthesis of Tryptamine Derivatives from Indoles: Exploiting N-Protected β-Amino Alcohols as Alkylating Agents, file e18b865c-f506-1ee6-e053-3a05fe0ae544
|
238
|
|
Therapeutic uses of melatonin and melatonin derivatives: a patent review (2012-2014), file e18b865d-5d7b-1ee6-e053-3a05fe0ae544
|
184
|
|
Antidepressant-like activity and cardioprotective effects of fatty acid amide hydrolase inhibitor URB694 in socially stressed Wistar Kyoto rats, file e18b865d-5ccd-1ee6-e053-3a05fe0ae544
|
116
|
|
Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines, file e18b865d-51fd-1ee6-e053-3a05fe0ae544
|
96
|
|
Synthesis of 2-substituted tryptophans via a C3- to C2-alkyl migration, file e18b865b-8cda-1ee6-e053-3a05fe0ae544
|
86
|
|
Selective Melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways, file e18b865d-52b9-1ee6-e053-3a05fe0ae544
|
76
|
|
New Antimicrobials Targeting Bacterial RNA Polymerase Holoenzyme Assembly Identified with an in Vivo BRET-Based Discovery Platform, file e18b865d-9311-1ee6-e053-3a05fe0ae544
|
74
|
|
Synthesis of Tryptamine Derivatives via a Direct, One-Pot Reductive Alkylation of Indoles, file e18b865b-8a98-1ee6-e053-3a05fe0ae544
|
65
|
|
Design, synthesis and biological activity of hydrogen peroxide responsive arylboronate melatonin hybrids, file e18b865d-742e-1ee6-e053-3a05fe0ae544
|
58
|
|
Cardioprotective effects of fatty acid amide hydrolase inhibitor URB694, in a rodent model of trait anxiety, file e18b865b-ca76-1ee6-e053-3a05fe0ae544
|
54
|
|
Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit, file e18b865d-5aa5-1ee6-e053-3a05fe0ae544
|
52
|
|
Antiproliferative and pro-apoptotic activity of melatonin analogues on melanoma and breast cancer cells, file e18b865c-6f9c-1ee6-e053-3a05fe0ae544
|
51
|
|
Tetrahydroquinoline Ring as a Versatile Bioisostere of Tetralin for Melatonin Receptor Ligands, file e18b865d-5f08-1ee6-e053-3a05fe0ae544
|
39
|
|
Direct, One-Pot Reductive Alkylation of Anilines with Functionalized Acetals Mediated by Triethylsilane and TFA. Straightforward Route for Unsymmetrically Substituted Ethylenediamine, file e18b865b-846c-1ee6-e053-3a05fe0ae544
|
11
|
|
New classes of potent heparanase inhibitors from ligand-based virtual screening, file e18b865d-4a4a-1ee6-e053-3a05fe0ae544
|
11
|
|
N-(Substituted-anilinoethyl)acylamides: Design, Synthesis and Pharmacological Characterization of a New Class of Melatonin Receptor Ligands, file e18b865b-7d4c-1ee6-e053-3a05fe0ae544
|
10
|
|
NAAA-regulated lipid signaling governs the transition from acute to chronic pain, file e18b865d-be6c-1ee6-e053-3a05fe0ae544
|
8
|
|
Synthesis and Characterization of New Bivalent Agents as Melatonin- and Histamine H3-Ligands, file e18b865b-aba9-1ee6-e053-3a05fe0ae544
|
7
|
|
Melatonin MT1 and MT2 Receptors Exhibit Distinct Effects in the Modulation of Body Temperature across the Light/Dark Cycle, file e18b865c-d875-1ee6-e053-3a05fe0ae544
|
7
|
|
Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria, file e18b865d-47d5-1ee6-e053-3a05fe0ae544
|
7
|
|
Design and synthesis of N-[3,3-diphenyl-propenyl]alkanamides as a novel class of potent MT2-selective Melatonin receptor ligands, file e18b865b-7d49-1ee6-e053-3a05fe0ae544
|
6
|
|
2-Arylmelatonin analogues: Probing the 2-phenyl binding pocket of melatonin MT1 and MT2 receptors, file d961becf-cd0a-41bf-947d-dde7ba57c160
|
5
|
|
N-(Anilinoethyl)amide Melatonergic Ligands with Improved Water Solubility and Metabolic Stability, file e18b865d-aa68-1ee6-e053-3a05fe0ae544
|
5
|
|
Regioselective one-step alkoxy-aryloxycarbonylation of alkenes, file 4019a610-3780-4e41-b4fe-2e0b487a7142
|
4
|
|
Structural requirements for inhibitors of poly(ADP-ribose) polymerase., file e18b865b-78c3-1ee6-e053-3a05fe0ae544
|
4
|
|
Analysis of structure-activity relationships for MT2 selective antagonists by melatonin MT1 and MT2 receptor models, file e18b865b-7d45-1ee6-e053-3a05fe0ae544
|
4
|
|
Organocatalyzed coupling of indoles with dehydroalanine esters: synthesis of bis(indolyl)propanoates and indolacrylates, file e18b865b-88e3-1ee6-e053-3a05fe0ae544
|
4
|
|
Homology models of melatonin receptors: challenges and recent advances, file e18b865b-afd2-1ee6-e053-3a05fe0ae544
|
4
|
|
Radiosynthesis and In Vivo Evaluation of Four Positron Emission Tomography Tracer Candidates for Imaging of Melatonin Receptors, file 3b6d69a6-598b-4ddf-9ac9-227e49452462
|
3
|
|
Anxiolytic effects of the melatonin MT2 receptor partial agonist UCM765: Comparison with melatonin and diazepam, file e18b865b-afd3-1ee6-e053-3a05fe0ae544
|
3
|
|
In silico drug discovery of melatonin receptor ligands with therapeutic potential, file 8847a687-e307-4654-99b1-047851a426c4
|
2
|
|
N-Acylethanolamine Acid Amidase (NAAA): Structure, Function, and Inhibition, file d84e77b1-b940-46ee-a6ea-29b146b4af47
|
2
|
|
Melatonin antagonizes apoptosis via receptor interaction in U937 monocytic cell, file e18b865b-8306-1ee6-e053-3a05fe0ae544
|
2
|
|
Melatonin receptor agonists: new options for insomnia and depression treatment, file e18b865b-a8da-1ee6-e053-3a05fe0ae544
|
2
|
|
Tetrahydroquinoline Ring as a Versatile Bioisostere of Tetralin for Melatonin Receptor Ligands, file e18b865c-9b02-1ee6-e053-3a05fe0ae544
|
2
|
|
Selective Melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways, file e18b865d-5bc0-1ee6-e053-3a05fe0ae544
|
2
|
|
Antidepressant-like activity and cardioprotective effects of fatty acid amide hydrolase inhibitor URB694 in socially stressed Wistar Kyoto rats, file e18b865d-5db2-1ee6-e053-3a05fe0ae544
|
2
|
|
Combined Effect of Palladium Catalyst and the Alcohol to Promote the Uncommon Bis‐Alkoxycarbonylation of Allylic Substrates, file e18b865d-a954-1ee6-e053-3a05fe0ae544
|
2
|
|
Diastereospecific Bis-alkoxycarbonylation of 1,2-Disubstituted Olefins Catalyzed by Aryl α-Diimine Palladium(II) Catalysts, file 8fdf04ab-9b2d-49ad-bcf2-984d3ef1f56b
|
1
|
|
ONE-POT SYNTHESIS OF SUCCINATES BEARING TWO DIFFERENT ESTER GROUPS THROUGH A SELECTIVE BIS-ALKOXYCARBONYLATION REACTION, file 98456403-b609-4a5b-b925-c37b668562ac
|
1
|
|
Synthesis and Configuration Determination of All Enantiopure Stereoisomers of the Melatonin Receptor Ligand 4-Phenyl-2-propionamidotetralin using an Expedient Optical Resolution of 4-Phenyl-2-tetralone, file e18b865b-8544-1ee6-e053-3a05fe0ae544
|
1
|
|
Brønsted Acid-Catalyzed Bisindolization of α-amido acetals: Synthesis and Anticancer activity of bis(indolyl)ethanamino derivatives, file e18b865b-89f5-1ee6-e053-3a05fe0ae544
|
1
|
|
Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines, file e18b865b-a413-1ee6-e053-3a05fe0ae544
|
1
|
|
Diastereo- and enantioselective hydrogenation of a challenging enamide derived from 4-phenyl-2-tetralone: an appealing shortcut towards enantiopure cis-2-aminotetraline derivatives, file e18b865b-a711-1ee6-e053-3a05fe0ae544
|
1
|
|
ST1936 stimulates cAMP, Ca2+, ERK1/2 and Fyn Kinase through a full activation of cloned hman 5-HT6 receptors, file e18b865b-a804-1ee6-e053-3a05fe0ae544
|
1
|
|
An improved synthesis of cis-4-phenyl-2-propionamidotetralin (4-P-PDOT): a selective MT2 melatonin receptor antagonist., file e18b865b-aa4e-1ee6-e053-3a05fe0ae544
|
1
|
|
Towards the development of 5-HT7 ligands combining serotonin-like and arylpiperazine moieties, file e18b865b-aba1-1ee6-e053-3a05fe0ae544
|
1
|
|
Bivalent Ligand Approach on N-[2-[(3-methoxyphenyl)methylamino]ethyl]acetamide. Synthesis, Binding Affinity and Intrinsic Acivity for MT(1) and MT(2) melatonin Receptors., file e18b865b-ad36-1ee6-e053-3a05fe0ae544
|
1
|
|
Pharmacokinetic and pharmacodynamic evaluation of ramelteon : an insomnia therapy, file e18b865b-ad39-1ee6-e053-3a05fe0ae544
|
1
|
|
Synthetic Melatonin Receptor Ligands, file e18b865b-afcb-1ee6-e053-3a05fe0ae544
|
1
|
|
Melatonin, non-selective MT1/MT2 and selective MT2 receptor agonists: differential effects on the 24-hr vigilance states, file e18b865b-afcf-1ee6-e053-3a05fe0ae544
|
1
|
|
MT1-Selective Melatonin Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Dynamics Investigation of N-{[(3-O-Substituted)anilino]alkyl}amides, file e18b865b-afd4-1ee6-e053-3a05fe0ae544
|
1
|
|
Design, synthesis and biological activity of hydrogen peroxide responsive arylboronate melatonin hybrids, file e18b865c-bf3f-1ee6-e053-3a05fe0ae544
|
1
|
|
New Antimicrobials Targeting Bacterial RNA Polymerase Holoenzyme Assembly Identified with an in Vivo BRET-Based Discovery Platform, file e18b865c-f067-1ee6-e053-3a05fe0ae544
|
1
|
|
Iridium-Catalyzed Direct Synthesis of Tryptamine Derivatives from Indoles: Exploiting N-Protected β-Amino Alcohols as Alkylating Agents, file e18b865c-f09a-1ee6-e053-3a05fe0ae544
|
1
|
|
Antidepressant-like effects of pharmacological inhibition of FAAH activity in socially isolated female rats, file e18b865d-480d-1ee6-e053-3a05fe0ae544
|
1
|
|
MT1 and MT2 melatonin receptors play opposite roles in brain cancer progression, file e18b865d-4a4e-1ee6-e053-3a05fe0ae544
|
1
|
|
Front Cover Picture: Bis‐Alkoxycarbonylation of Acrylic Esters and Amides for the Synthesis of 2‐Alkoxycarbonyl or 2‐Carbamoyl Succinates (Adv. Synth. Catal. 3/2020), file e18b865d-af0c-1ee6-e053-3a05fe0ae544
|
1
|
|
2-Arylmelatonin analogues: Probing the 2-phenyl binding pocket of melatonin MT1 and MT2 receptors, file eda2b55a-93da-457f-8131-b1087d062aae
|
1
|
| Totale |
1.329 |