A new flexible strategy for the synthesis of diversely functionalized pyridazines from 4-chloro-1,2-diaza-1,3-butadienes and active methylene compounds is reported. The high chemoselectivity of this approach offers access to structural precursors of GABA-A antagonist analogues.
A Novel and Convenient Protocol for the Synthesis of Pyridazines
ATTANASI, ORAZIO ANTONIO;FAVI, GIANFRANCO;FILIPPONE, PAOLINO;PERRULLI, FRANCESCA ROMANA;SANTEUSANIO, STEFANIA
2009
Abstract
A new flexible strategy for the synthesis of diversely functionalized pyridazines from 4-chloro-1,2-diaza-1,3-butadienes and active methylene compounds is reported. The high chemoselectivity of this approach offers access to structural precursors of GABA-A antagonist analogues.File in questo prodotto:
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