A very simple domino reaction under solvent free conditions of various piridine-like heterocycles with 1,2-diaza-1,3-dienes produces in good yields imidazo[1,2-a]pyridines, imidazo[1,2-a]quinolines and imidazo[2,1-a]isoquinolines. The advantage of this one-pot transformation lies in the use of simple pyridine-like compounds without pre-functionalization of the starting heterocycles.
A Novel Solvent-free Approach to Imidazole containing Nitrogen-Bridgehead Heterocycles
ATTANASI, ORAZIO ANTONIO;BIANCHI, LUCA;CAMPISI, LINDA ANTONELLA;DE CRESCENTINI, LUCIA;FAVI, GIANFRANCO;MANTELLINI, FABIO
2013
Abstract
A very simple domino reaction under solvent free conditions of various piridine-like heterocycles with 1,2-diaza-1,3-dienes produces in good yields imidazo[1,2-a]pyridines, imidazo[1,2-a]quinolines and imidazo[2,1-a]isoquinolines. The advantage of this one-pot transformation lies in the use of simple pyridine-like compounds without pre-functionalization of the starting heterocycles.File in questo prodotto:
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