1,2-Diaza-1,3-dienes bearing electron withdrawing groups react with electron-poor alkenes by means of an uncommon aza-Diels-Alder reaction furnishing novel tetrahydropyridazines with high regio- and stereoselectivity. Conducing these cycloadditions in solvent free conditions under thermal conditions the reaction times are significantly reduced, the yields are improved and the stereoselectivity remained unchanged.
Novel Tetrahydropyridazines by Unusual Aza-Diels-Alder Reaction of Electron-poor 1,2-Diaza-1,3-dienes with Electron-poor Alkenes under Solvent Free Conditions
ATTANASI, ORAZIO ANTONIO;BIANCHI, LUCA;MANTELLINI, FABIO;
2013
Abstract
1,2-Diaza-1,3-dienes bearing electron withdrawing groups react with electron-poor alkenes by means of an uncommon aza-Diels-Alder reaction furnishing novel tetrahydropyridazines with high regio- and stereoselectivity. Conducing these cycloadditions in solvent free conditions under thermal conditions the reaction times are significantly reduced, the yields are improved and the stereoselectivity remained unchanged.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
