Preliminary evidence on the accumulation of polyamine-protein conjugates (PPCs) was obtained in uremic patients. The presence of these substances in the plasma of hemodialysis (HD) patients was evaluated, and their possible contribution to uremic anemia was investigated by testing the effect of PPC synthesized in vitro on erythroid cell proliferation.

Polymeric protein-polyamine conjugates: a new class of uremic toxins affecting erythropoiesis

BENEDETTI, SERENA;CANESTRARI, FRANCO;
2001

Abstract

Preliminary evidence on the accumulation of polyamine-protein conjugates (PPCs) was obtained in uremic patients. The presence of these substances in the plasma of hemodialysis (HD) patients was evaluated, and their possible contribution to uremic anemia was investigated by testing the effect of PPC synthesized in vitro on erythroid cell proliferation.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11576/2628394
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