Event-related potentials to emotional stimuli in migrainous children

The present preliminary study was aimed at investigating the electrocortical correlates of attentional allocation toward emotional stimuli in children and adolescents with migraine by means of the event-related potentials. The electroencephalogram was continuously recorded in 7 migrainous children and 8 healthy controls while they were looking at a series of pleasant, neutral, and unpleasant pictures. The mean amplitude of the Negative Central component of the event-related potentials was computed as an index of the allocation of attentional resources to the presented stimuli. Relative to controls, children with migraine displayed reduced fronto-central negativity and larger posterior positivity in response to emotional pictures. This effect was already evident, overall, in a time window preceding the Negative Central component. The smaller cortical negativity in response to emotional stimuli suggests reduced attentional engagement toward emotionally relevant stimuli, or might be interpreted in terms of advanced brain maturation in migraine children.