Anion complexation, transport and structural studies of a series of bis-methylurea compounds

A new family of bis-methylureas (L-1-L-6) have been synthesised and their ability to bind anions both in solution and in the solid state and to transport them through lipid membrane have been studied. From the solid state studies it has emerged that various conformations can be adopted by the receptors allowing the isolation of complexes of different stoichiometries (from 1:1 to 1:3). The transport studies highlighted the possibility to use bis-methylureas to mediate Cl- transport across membranes.