Background The COVID-19 pandemic induced an astonishing impact on global mental health, especially in vulnerable populations such as breast cancer (BC) survivors. In this study, we described the effects of a multidisciplinary home-based lifestyle intervention in Italian women BC survivors during the COVID-19 pandemic period. Material (patients) and methods Thirty women involved in the ongoing MoviS trial (protocol: NCT 04818359) with stage 0-III non-metastatic BC and with risk factors for recurrence (age: 53.5±7.6; BMI: 25.3±4.9) were recruited within 12-month post-surgery. Between January 2020 and January 2021, a 3-month lifestyle intervention based on psychological counseling, nutrition, and exercise was carried out. Participants were asked to complete questionnaires for quality of life indicators (European Organization for Research and Treatment of Cancer Quality of Life, EORTC-QLQ-C30) and psychological health measures such as fatigue (Brief Fatigue Inventory, BFI), distress (Distress Thermometer, DT and Psychological Distress Inventory, PDI), cancer-related fatigue (Verbal Rating Scale, VRS), and mood states (Profile of Mood States Questionnaire, POMS). All participants were assessed at: T0 (baseline), T1 (3-month), and follow-up at T2 and T3 (6- and 12-month, respectively) to measure primary (quality of life indicators) and secondary (psychological health) outcomes. Friedman nonparametric test and Wilcoxon signed rank test (with Bonferroni correction) were applied. 21/05/2023 10:10:47 Results Compared to baseline (T0), at T1 most of the quality of life indicators (i.e., symptoms of fatigue and general health) were improved (p < 0.0166) except a worsening in participants' social functioning ability. Also, the perception of the severity of fatigue, distress, cancer-related fatigue, depression, and anger is enhanced. Compared to baseline (T0), at T3 we mainly observed a stable condition with T0-T1 pairwise comparison, however, other secondary outcomes (i.e., fatigue, mood state, confusion, and anxiety) significantly improved. Conclusions Our preliminary findings support the proposal of this lifestyle intervention for BC survivors. Despite the home-confinement due to the COVID-19 pandemic, the intervention surprisingly improved the quality of life indicators and psychological health of the participants.
25th National Congress of Italian Association of Medical Oncology (AIOM) 10-12 November 2023 – Rome Marriott Park Hotel, Italy
Emili R.;Vagnini D.;Natalucci V.;Vallorani L.;Pietrelli A.;Panico A. R.;Ferri Marini C.;Lucertini F.;Annibalini G.;Sisti D.;Rocchi M. B. L.;Saita E.;Barbieri E.
2023
Abstract
Background The COVID-19 pandemic induced an astonishing impact on global mental health, especially in vulnerable populations such as breast cancer (BC) survivors. In this study, we described the effects of a multidisciplinary home-based lifestyle intervention in Italian women BC survivors during the COVID-19 pandemic period. Material (patients) and methods Thirty women involved in the ongoing MoviS trial (protocol: NCT 04818359) with stage 0-III non-metastatic BC and with risk factors for recurrence (age: 53.5±7.6; BMI: 25.3±4.9) were recruited within 12-month post-surgery. Between January 2020 and January 2021, a 3-month lifestyle intervention based on psychological counseling, nutrition, and exercise was carried out. Participants were asked to complete questionnaires for quality of life indicators (European Organization for Research and Treatment of Cancer Quality of Life, EORTC-QLQ-C30) and psychological health measures such as fatigue (Brief Fatigue Inventory, BFI), distress (Distress Thermometer, DT and Psychological Distress Inventory, PDI), cancer-related fatigue (Verbal Rating Scale, VRS), and mood states (Profile of Mood States Questionnaire, POMS). All participants were assessed at: T0 (baseline), T1 (3-month), and follow-up at T2 and T3 (6- and 12-month, respectively) to measure primary (quality of life indicators) and secondary (psychological health) outcomes. Friedman nonparametric test and Wilcoxon signed rank test (with Bonferroni correction) were applied. 21/05/2023 10:10:47 Results Compared to baseline (T0), at T1 most of the quality of life indicators (i.e., symptoms of fatigue and general health) were improved (p < 0.0166) except a worsening in participants' social functioning ability. Also, the perception of the severity of fatigue, distress, cancer-related fatigue, depression, and anger is enhanced. Compared to baseline (T0), at T3 we mainly observed a stable condition with T0-T1 pairwise comparison, however, other secondary outcomes (i.e., fatigue, mood state, confusion, and anxiety) significantly improved. Conclusions Our preliminary findings support the proposal of this lifestyle intervention for BC survivors. Despite the home-confinement due to the COVID-19 pandemic, the intervention surprisingly improved the quality of life indicators and psychological health of the participants.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
