XV National Congress Sismes

Title: Monitoring physical activity level in breast cancer survivors using the SenseWear Armband® during and after 6-month of lifestyle intervention. Abstract: It is known that physical activity (PA) improves health-related outcomes in breast cancer survivors (BCS). This study aims to compare PA level (PAL), objectively measured with wearable devices, in BCS. Thirty-four sedentary BCS (age 52.21±8.85 years) were randomized into a control (CA, n=13) and intervention (IA, n=21) arm. Both groups received current lifestyle recommendations. The IA received a 3-month supervised aerobic training program with incremental intensity (40-70% of heart rate reserve) and duration (20-60 min) for 3 days/week (MoviS trial: NCT04818359). The PAL was monitored for 5 consecutive days (24h/d) using SenseWear Armband®. PA duration (min), metabolic equivalents (METs), energy expenditure (kcal), and moderate or vigorous PA (min) were evaluated in the first 2 weeks after lifestyle recommendations (T0) and after 3- (T1) and 6- (T2) month. V̇O2max (mL·min−1 kg−1) was evaluated at the beginning (Baseline) and T1 and T2 time points. Outcomes were analyzed by a mixed ANOVA with Bonferroni corrected contrasts to evaluate changes over time (p-value was set as 0.05). Vigorous PA slightly increased at T1 compared to T0 in both arms (CA: 1.0±4.2 min; IA: 4.4 ±9.0 min; p<0.001, η2p = 0.340) and returned to T0 values at T2. Significant group x time interactions were found in PA duration (p=0.003, η2p = 0.245), energy expenditure (p=0.003, η2p = 0.240) and moderate PA (p=0.010, η2p = 0.192). Bonferroni corrected contrasts showed an increase in PA duration (19.0±45.5 min), energy expenditure (97.5±171.3 kcal), and moderate PA (9.6±43.4 min) in IA from T0 to T1. Conversely, PAL parameters decreased from T0 to T1 in the CA (PA duration: −21.3±33.9 min; energy expenditure: −80.3±131.4 kcal; moderate PA: −21.8±31.5 min). All PAL parameters returned to T0 values at T2 in both IA and CA. V̇O2max increased in IA from baseline to T1 (2.6±3.8 mL·min−1 kg−1, p=0.004) and T2 (2.6±3.8 mL·min−1 kg−1, p=0.003) with no changes in CA over time. Both CA and IA reached a moderate PAL in the first 2 weeks of lifestyle recommendation. Conversely, at 3-month, PA duration, energy expenditure, and moderate PAL were significantly increased in the IA, while CA showed decreased PAL. PAL parameters returned to T0 values at T2 in both CA and IA. Interestingly, V̇O2max increased only in the IA at T1 and was maintained at T2. The supervised training is superior to recommendations alone to increase and maintain PAL and cardiorespiratory fitness in BCS.