Sfoglia per Autore
Small molecule-mediated inhibition of the oxidoreductase ERO1A restrains aggressive breast cancer by impairing VEGF and PD-L1 in the tumor microenvironment
2025 Varone, Ersilia; Retini, Michele; Cherubini, Alessandro; Chernorudskiy, Alexander; Marrazza, Alice; Guidarelli, Andrea; Cagnotto, Alfredo; Beeg, Marten; Gobbi, Marco; Fumagalli, Stefano; Bolis, Marco; Guarrera, Luca; Barbera, Maria Chiara; Grasselli, Chiara; Bleve, Augusto; Generali, Daniele; Milani, Manuela; Mari, Michele; Salmona, Mario; Piersanti, Giovanni; Bottegoni, Giovanni; Broggini, Massimo; Janssen-Heininger, Yvonne M. W.; Cho, Jaehyung; Cantoni, Orazio; Zito, Ester
Unveiling the Link Between NADPH Oxidase 2 Activation and Mitochondrial Superoxide Formation in Leukemic Cell Killing Induced by Arsenic Trioxide
2024 Spina, Andrea; Guidarelli, Andrea; Buffi, Gloria; Fiorani, Mara; Cantoni, Orazio
Arsenite enhances ERO1α expression via ryanodine receptor dependent and independent mechanisms
2023 Guidarelli, Andrea; Spina, Andrea; Fiorani, Mara; Zito, Ester; Cantoni, Orazio
ERO1α primes the ryanodine receptor to respond to arsenite with concentration dependent Ca2+ release sequentially triggering two different mechanisms of ROS formation
2023 Guidarelli, Andrea; Spina, Andrea; Buffi, Gloria; Blandino, Giulia; Fiorani, Mara; Cantoni, Orazio
Clozapine suppresses NADPH oxidase activation, counteracts cytosolic H2O2, and triggers early onset mitochondrial dysfunction during adipogenesis of human liposarcoma SW872 cells
2023 Blandino, Giulia; Fiorani, Mara; Canonico, Barbara; De Matteis, Rita; Guidarelli, Andrea; Montanari, Mariele; Buffi, Gloria; Coppo, Lucia; Arnér, Elias S J; Cantoni, Orazio
Mitochondrial ROS, ER Stress, and Nrf2 Crosstalk in the Regulation of Mitochondrial Apoptosis Induced by Arsenite
2022 Cantoni, Orazio; Zito, Ester; Guidarelli, Andrea; Fiorani, Mara; Ghezzi, Pietro
Crosstalk between ERO1α and ryanodine receptor in arsenite-dependent mitochondrial ROS formation
2022 Spina, Andrea; Guidarelli, Andrea; Fiorani, Mara; Varone, Ersilia; Catalani, Alessia; Zito, Ester; Cantoni, Orazio
Loss-of-rescue of Ryr1I4895T-related pathology by the genetic inhibition of the ER stress response mediator CHOP
2022 Germani, Serena; Marchetti, Alessia Celeste; Guidarelli, Andrea; Cantoni, Orazio; Sorrentino, Vincenzo; Zito, Ester
Inhibition of activity/expression, or genetic deletion, of ERO1α blunts arsenite geno- and cyto-toxicity
2022 Guidarelli, Andrea; Spina, Andrea; Fiorani, Mara; Zito, Ester; Cantoni, Orazio
Functional organization of the endoplasmic reticulum dictates the susceptibility of target cells to arsenite-induced mitochondrial superoxide formation, mitochondrial dysfunction and apoptosis
2021 Guidarelli, Andrea; Catalani, Alessia; Spina, Andrea; Varone, Ersilia; Fumagalli, Stefano; Zito, Ester; Fiorani, Mara; Cantoni, Orazio
Arsenite impinges on endoplasmic reticulum-mitochondria crosstalk to elicit mitochondrial ROS formation and downstream toxicity
2021 Cantoni, Orazio; Zito, Ester; Fiorani, Mara; Guidarelli, Andrea
Temporal correlation of morphological and biochemical changes with the recruitment of different mechanisms of reactive oxygen species formation during human SW872 cell adipogenic differentiation
2021 Fiorani, Mara; De Matteis, Rita; Canonico, Barbara; Blandino, Giulia; Mazzoli, Alessandro; Montanari, Mariele; Guidarelli, Andrea; Cantoni, Orazio
Ascorbic Acid Route to the Endoplasmic Reticulum: Function and Role in Disease
2021 Pozzer, Diego; Invernizzi, Roberto William; Blaauw, Bert; Cantoni, Orazio; Zito, Ester
Mitochondrial reactive oxygen species: the effects of mitochondrial ascorbic acid vs untargeted and mitochondria-targeted antioxidants
2020 Fiorani, Mara; Guidarelli, Andrea; Cantoni, Orazio
Arsenite-induced mitochondrial superoxide formation: time and concentration requirements for the effects of the metalloid on the endoplasmic reticulum and mitochondria
2020 Guidarelli, Andrea; Cerioni, Liana; Fiorani, Mara; Catalani, Alessia; Cantoni, Orazio
SVCT2-DEPENDENT PLASMA AND MITOCHONDRIAL MEMBRANE TRANSPORT OF ASCORBIC ACID IN DIFFERENTIATING MYOBLASTS
2020 Fiorani, Mara; Scotti, Maddalena; Guidarelli, Andrea; Burattini, Sabrina; Falcieri, Elisabetta; Cantoni, Orazio
The compartmentalised nature of the mechanisms governing superoxide formation and scavenging in cells exposed to arsenite
2019 Guidarelli, Andrea; Fiorani, Mara; Cerioni, Liana; Cantoni, Orazio
Prostaglandin E2 Signals Through E Prostanoid Receptor 2 to Inhibit Mitochondrial Superoxide Formation and the Ensuing Downstream Cytotoxic and Genotoxic Effects Induced by Arsenite
2019 Cerioni, Liana; Guidarelli, Andrea; Fiorani, Mara; Cantoni, Orazio
Calcium signals between the ryanodine receptor- and mitochondria critically regulate the effects of arsenite on mitochondrial superoxide formation and on the ensuing survival vs apoptotic signaling
2019 Guidarelli, Andrea; Fiorani, Mara; Cerioni, Liana; Cantoni, Orazio
Differentiation of Promonocytic U937 Cells to Monocytes Is Associated with Reduced Mitochondrial Transport of Ascorbic Acid
2018 Scotti, Maddalena; Fiorani, Mara; Guidarelli, Andrea; Cantoni, Orazio
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