IRIS
TARZIA, GIORGIO
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 20.728
EU - Europa 15.146
AS - Asia 5.632
Continente sconosciuto - Info sul continente non disponibili 83
AF - Africa 46
SA - Sud America 34
OC - Oceania 29
AN - Antartide 1
Totale 41.699
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 20.612
GB - Regno Unito 6.096
CN - Cina 4.028
UA - Ucraina 2.750
SE - Svezia 1.606
IT - Italia 1.602
TR - Turchia 1.104
DE - Germania 841
FI - Finlandia 837
IE - Irlanda 590
FR - Francia 241
RU - Federazione Russa 189
IN - India 107
CA - Canada 105
SG - Singapore 100
BE - Belgio 96
JP - Giappone 90
EU - Europa 80
VN - Vietnam 64
KR - Corea 53
NL - Olanda 52
PL - Polonia 50
RO - Romania 41
AT - Austria 32
AU - Australia 25
CH - Svizzera 24
ES - Italia 23
KE - Kenya 21
HK - Hong Kong 17
IR - Iran 16
TG - Togo 16
BR - Brasile 12
ID - Indonesia 10
CL - Cile 9
HU - Ungheria 9
AL - Albania 8
MX - Messico 8
GR - Grecia 7
DK - Danimarca 6
SA - Arabia Saudita 6
EE - Estonia 5
HR - Croazia 5
AM - Armenia 4
BD - Bangladesh 4
BG - Bulgaria 4
IQ - Iraq 4
LA - Repubblica Popolare Democratica del Laos 4
LU - Lussemburgo 4
MA - Marocco 4
NZ - Nuova Zelanda 4
PE - Perù 4
PK - Pakistan 4
RS - Serbia 4
SI - Slovenia 4
A2 - ???statistics.table.value.countryCode.A2??? 3
CO - Colombia 3
IL - Israele 3
LB - Libano 3
PH - Filippine 3
PT - Portogallo 3
SK - Slovacchia (Repubblica Slovacca) 3
TW - Taiwan 3
ZA - Sudafrica 3
AR - Argentina 2
BO - Bolivia 2
BY - Bielorussia 2
CZ - Repubblica Ceca 2
FK - Isole Falkland (Malvinas) 2
JM - Giamaica 2
MD - Moldavia 2
NO - Norvegia 2
SL - Sierra Leone 2
AE - Emirati Arabi Uniti 1
GS - Georgia del Sud e Isole Sandwich Australi 1
IM - Isola di Man 1
IS - Islanda 1
KW - Kuwait 1
LK - Sri Lanka 1
LT - Lituania 1
LV - Lettonia 1
ME - Montenegro 1
MO - Macao, regione amministrativa speciale della Cina 1
MY - Malesia 1
PA - Panama 1
SM - San Marino 1
Totale 41.699
Salva come PNG Salva come JPEG
Città #
Southend 5.676
Woodbridge 3.099
Ann Arbor 2.232
Jacksonville 2.211
Houston 2.108
Chandler 1.869
Fairfield 1.852
Nanjing 1.220
Ashburn 1.024
Cambridge 895
Izmir 876
Wilmington 826
Seattle 709
Dublin 532
Nanchang 465
San Mateo 345
Princeton 317
Helsinki 314
Beijing 311
Hebei 249
Shenyang 242
Düsseldorf 226
Tianjin 210
Changsha 193
New York 192
Boardman 175
Jiaxing 172
Kunming 162
Istanbul 145
Velikiy Novgorod 125
Brussels 94
Mülheim 93
San Diego 84
Des Moines 83
Bremen 81
Urbino 81
Jinan 75
Hangzhou 69
San Francisco 69
Toronto 68
Orciano Di Pesaro 61
Shanghai 60
Lanzhou 59
Venice 56
Changchun 54
Dong Ket 54
Zhengzhou 54
Ningbo 53
Milan 51
Munich 50
Menlo Park 48
Seongnam 45
Dearborn 41
Kraków 40
Singapore 40
Norwalk 37
London 36
Amsterdam 35
Guangzhou 35
Haikou 35
Vienna 32
Los Angeles 28
Rome 28
Wuppertal 26
Auburn Hills 25
Leawood 21
Parma 21
Taizhou 21
Fuzhou 20
West Jordan 20
Redwood City 19
Ancona 18
Augusta 18
Timisoara 18
Florence 17
Lomé 16
Borås 15
Frankfurt am Main 15
Shenzhen 15
Edinburgh 14
Hefei 14
Mcallen 14
Orange 14
Cava De' Tirreni 13
Focsani 13
Melbourne 13
Palermo 13
Portland 13
Mumbai 12
Dormagen 11
Napoli 11
Nuremberg 11
Padova 11
Ardabil 10
Chicago 10
Hanoi 10
Scottsdale 10
Tokyo 10
Bologna 9
Hanover 9
Totale 31.351
Salva come PNG Salva come JPEG
Nome #
Inibitori dell’enzima NAAA (N-Acylethanolamine-Hydrolizing Acid Amidase) come nuovi agenti antinfiammatori 735
1,5-BENZODIAZEPINE-2,4-DIONE GASTRIN AND CHOLECYSTOKININ-B-RECEPTOR ANTAGONISTS 322
1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES AS LIGANDS AT THE GLYCINE-BINDING SITE OF THE N-METHYL-D-ASPARTATE RECEPTOR 319
1-(2-Alkylamidoethyl)-6-methoxyindole Derivatives: A New Class of Potent Indole Melatonin Analogues. 315
1-Aminocyclopropane-1-carboxylic acid derivatives as ligands at the glicine-site of the NMDA receptor. 302
1,7-DIHYDROPYRROLO[3,4-e][1,4]DIAZEPIN-2(3H)-ONE DERIVATIVES, AND THEIR USE AS ANTICONVULSANT AND ANTIANXIETY AGENTS 302
ORGANIC REACTIONS OF FLUOROXY COMPOUNDS: ADDITION REACTIONS OF UNACTIVATED AND DEACTIVATED UNSATURATED LINKAGES OF STEROIDS 251
ENOLATES OF 17,20:20,21-BISMETHYLENEDIOXYPREDNISONE 238
Scoperta del primo inibitore dell’enzima idrolasi delle ammidi degli acidi grassi (FAAH) ad azione periferica 238
Towards the development of 5-HT7 ligands combining serotonin-like and arylpiperazine moieties 232
Potent, Metabolically Stable 2-Alkyl-8-(2H-1,2,3-triazol-2-yl)-9H-adenines as Adenosine A2A Receptor Ligands 230
Divergent synthesis of novel 9-deazaxanthine derivatives via late-stage cross-coupling reactions 227
Tricyclic Alkylamides as Melatonin Receptor Ligands with Antagonist or Inverse Agonist Activity 223
Synthesis of benzo[1,2-d;3,4-d’]diimidazole and 1H-pyrazolo[4,3-b]pyridine as putative A2A receptor antagonists 218
Structure–Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability 215
2-n-Butyl- 9-methyl-8-(1,2,3)triazol-2-yl-9H-purin-6-ylamine and Analogues as A2A Adenosine Receptor Antagonists. Design, Synthesis, and Pharmacological Characterization 210
Synthesis and Biological Evaluation of Metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), A Potent Antagonist of the A2AAdenosine Receptor for the Treatment of Parkinson’s Disease 210
A new melatonin receptor ligand with mt1-agonist and MT2-antagonist properties 207
Synthesis and Biological Activity of new melatonin dimeric derivatives. 206
Alkyl 2 (Diphenyl-methyleneamino) acrylates in the Synthesis of α-Amino Acids 205
Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability 205
Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress 201
(E)-3-(2-(N-phenylcarbamoyl)vinyl)pyrrole-2-carboxylic acid derivatives. A novel class of glycine site antagonists. 199
Modulation of Anxiety Through Blockade of Anandamide Hydrolysis 199
Sintesi e studi di relazione struttura-attività/stabilità di carbammati inibitori dell’enzima FAAH 198
POSITIVE ION-MASS SPECTRA AND COLLISION-INDUCED DISSOCIATION OF SOME 2,3-DIDEHYDRO AMINO ACIDS 197
A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo 196
Identification of a Bioactive Impurity in a Commercial Sample of 6-Methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754) 192
4,5-Dihydroisoxazole and 4,5-dihydro-1,2,4-oxadiazole derivatives from cycloaddition reactions of nitrile oxides to alkyl N-(diphenylmethylene)-α ,β -dehydroamino acids 191
An improved route to cycloalka[b]pyrrole 2-carboxylates 189
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 188
3-(2-Carbamoylvinyl)-4,5-dimethylpyrrole-2-carboxylic acids as ligands at the NMDA glycine-binding site: a study on the 2-carbamoylvinyl chain modification 187
TEICOPLANIN HYDRAZIDES AS ANTIBACTERIALS 186
3,6-DISUBSTITUTED TRIAZOLO[3,4-a]PHTHALAZINE DERIVATIVES 184
10-(1-HYDROXYMETHYL)-11-OXO-1-AZATRICYCLOUNDEC-2-ENE-2-CARBOXYLIC ACID ESTERS USEFUL AS ANTIBACTERIAL AND PROCESS FOR THEIR PREPARATION 183
Toward the Definition of Stereochemical Requirements for MT(2)-Selective Antagonists and Partial Agonists by Studying 4-Phenyl-2-propionamidotetralin Derivatives 183
2,4,5-TRISUBSTITUTED OXAZOLES 181
N-(Anilinoethyl)amides: design and synthesis of metabolically stable, selective melatonin receptor ligands. 181
Synthesis and Structure–Activity Relationships of a Series of Pyrrole Cannabinoid Receptor Agonists 179
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation 177
Endocannabinoids in the Treatment of Mood Disorders: Evidence from Animal Models 176
Differentiation between isomeric 1-aminocyclopropane-1-carboxylic acid derivatives by means of chemical ionisation and mass selected collision induced dissociation 175
N (Diphenylmethylene)-α,β−didehydroamino Acid Esters. Thermal and Lewis Acid Induced Dimerizations 175
Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand 174
Synthesis of (E)-8-(3-Chlorostyryl)caffeine Analogues Leading to 9-Deazaxanthine Derivatives as Dual A2AAntagonists/MAO-B Inhibitors 174
Peripherally Restricted FAAH Inhibitors 174
GENERALISED ELECTROPHILIC FLUORINATION BY FLUOROXY COMPOUNDS 174
Plant-derived phenolic compounds prevent the DNA single-strand breakage and cytotoxicity induced by tert-butylhydroperoxide via an iron-chelating mechanism. 173
X-RAY STRUCTURE DETERMINATION OF MEXIPROSTIL, A NEW GASTROPROTECTIVE 16-METHOXY-16METHYL-PGE1 ANALOGUE 171
"Hot spots" in Medicinal Chemistry 171
Synthesis and Structure–Activity Relationship (SAR) of 2-Methyl-4-oxo-3-oxetanyl Carbamic Acid Esters, a Class of Potent N-Acylethanolamine Acid Amidase (NAAA) Inhibitors 171
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 170
5-(2-Ethyl-phenyl)-3-(3-methoxy-phenyl)-1H-[1,2,4]triazole (DL-111-IT ) and related compounds induce morphological apoptotic patterns in cultures of human tumor cell lines 168
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 168
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis 167
Synthesis, Enantiomeric Resolution and Structure-Activity Relationship Study for a Series of 10,11-Dihydro-5H-dibenzo[a,d]cycloheptene MT2 Receptor Antagonists. 167
Mechanisms of action and antiproliferative properties of URB631 in human breast cancer 167
SULLA MICELIANAMMIDE 166
MELATONIN RECEPTOR AGONISTS: SAR AND APPLICATIONS TO THE TREATMENT OF SLEEP-WAKE DISORDERS 165
SYNTHESIS AND BIOLOGICAL PROPERTIES OF N63-CARBOXAMIDES OF TEICOPLANIN ANTIBIOTICS. STRUCTURE-ACTIVITY RELATIONSHIPS. 165
Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain 164
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 164
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 163
5-halo-tryptamine derivatives used as ligands of the 5-ht6 and/or 5-ht7 serotonin receptors, preparation, and therapeutic use.. 162
Application of 3D-QSAR in the Rational Design of Receptor Ligands and Enzyme Inhibitors 162
UNIVERSITY EDUCATION OF MEDICINAL CHEMISTS: COMPARISON OF EIGHT COUNTRIES 161
The Fatty Acid Amide Hydrolase Inhibitor URB597 (Cyclohexylcarbamic Acid 3’-Carbamoylbiphenyl-3-yl Ester) Reduces Neuropathic Pain after Oral Administration in Mice 160
URB602 Inhibits Monoacylglycerol Lipase and Selectively Blocks 2-Arachidonoylglycerol Degradation in Intact Brain Slices 159
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 159
ANGIOTENSIN CONVERTING ENZYME INHIBITORS AS ANTIHYPERTENSIVE AGENTS: 1-[´2-MERCAPTOCYCLOALKYL`CARBONYL]-L-PROLINES 158
Reassessing the melatonin pharmacophore: enantiomeric resolution, pharmacological activity, structure analysis, and molecular modeling of a constrained chiral melatonin analogue. 158
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus 157
DEAMINOTEICOPLANIN AND ITS DERIVATIVES. SYNTHESIS, ANTIBACTERIAL ACTIVITY, AND BINDING STRENGTH TO Ac-D-ALA-D-ALA 155
6-(ALKYLAMINO)-3-ARYL-1,2,4-TRIAZOLO[3,4-A]PHTHALAZINES. A NEW CLASS OF BENZODIAZEPINE RECEPTOR LIGANDS 155
2,3-Dehydroamino acid derivatives as intermediates in the synthesis of heterocyclic compounds. 155
The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues 155
Design and synthesis of N-[3,3-diphenyl-propenyl]alkanamides as a novel class of potent MT2-selective Melatonin receptor ligands 154
SUITABILITY OF FAST-ION BOMBARDMENT MASS SPECTROMETRY FOR THE INVESTIGATION OF 11,4-DIHYDROPYRIDINE DERIVATIVES 154
Conformationally Restrained Melatonin Analogs: Synthesis, Binding Affinity for the Melatonin Receptor, Evaluation of the Biological Activity, and Molecular Modeling Study 153
O-Biphenyl-3-yl Carbamates as Peripheral FAAH Inhibitors: Synthesis and Structure–Activity (SAR) Relationship Studies 153
Melatonin prevents apoptosis induced by UV-B treatment in U937 cell line. 152
Electron Impact Ionization and Fast Atom Bombardment Mass Spectrometry of Some 3,3-Dimethyl-1-(Isoxazol-3-yl)-triazenes. A New Class of Potential Anticancer Agents. 152
Bivalent Ligand Approach on N-[2-[(3-methoxyphenyl)methylamino]ethyl]acetamide. Synthesis, Binding Affinity and Intrinsic Acivity for MT(1) and MT(2) melatonin Receptors. 152
Modulation of anxiety through blockade of anandamide hydrolysis 152
STRUCTURE-AFFINITY RELATIONSHIPS OF INDOLE-BASED MELATONIN ANALOGS 151
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice 151
PYRROLOPYRIDINE ANALOGS OF NALIDIXIC ACID. 2. PYRROLO[3,4-b]PYRIDINES 151
Sintesi e studi biologici preliminari su analoghi di URB937, il primo inibitore ad azione periferica dell'enzima FAAH 150
N-(DIPHENYLMETHYLENE)-ALPHA,BETA-DIDEHYDROAMINO ACID ESTERS. THERMAL AND LEWIS ACID INDUCED DIMERIZATIONS 149
METABOLIC PATHWAYS OF THE ANTIHYPERTENSIVE AGENT, N-(2,5-DIMETHYL-1H-PYRROL-1-YL)-6-(4-MORPHOLINYL)-3-PYRIDAZINAMINE HYDROCHLORIDE. II.STUDIES IN THE DOG 149
Metastable ion studies in the characterization melatonin isomers 149
Recent advances in the development of melatonin MT1 and MT2 receptor agonists 149
Derivati 2-Acilamminoalchilindolici come Antagonisti/Agonisti Parziali della Melatonina 149
2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists 148
SYNTHESIS OF BETA-AMINOPYRROLES 147
THREE-DIMENSIONAL QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP STUDIES ON SELECTED MT1 AND MT2 MELATONIN RECEPTOR LIGANDS: REQUIREMENTS FOR SUBTYPE SELECTIVITY AND INTRINSIC ACTIVITY MODULATION 146
N-Acyl-5- and -2,5-substituted tryptamines: synthesis, activity and affinity for human mt1 and MT2 melatonin receptors 146
An endocannabinoid mechanism for stress-induced analgesia 146
Melatonin receptor ligands: synthesis of new melatonin derivatives and comprehensive comparative molecular field analysis (CoMFA) study. 146
Anxiolytic effects of the melatonin MT2 receptor partial agonist UCM765: Comparison with melatonin and diazepam 146
Totale 18.754
Salva come PNG Salva come JPEG
Categoria #
all - tutte 120.214
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 120.214
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20205.854 0 275 436 1.577 276 626 562 616 315 522 255 394
2020/20214.711 133 401 155 592 237 371 263 371 700 425 743 320
2021/20223.235 188 375 398 514 74 84 111 202 219 136 41 893
2022/20235.271 613 291 153 643 460 1.157 15 428 868 137 354 152
2023/20241.271 165 132 78 157 81 294 65 80 19 88 22 90
2024/2025506 285 221 0 0 0 0 0 0 0 0 0 0
Totale 41.981