IRIS
TARZIA, GIORGIO
 Distribuzione geografica
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Continente #
NA - Nord America 29.337
EU - Europa 26.618
AS - Asia 10.751
SA - Sud America 698
AF - Africa 143
Continente sconosciuto - Info sul continente non disponibili 84
OC - Oceania 38
AN - Antartide 1
Totale 67.670
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Nazione #
US - Stati Uniti d'America 29.070
NL - Olanda 9.519
GB - Regno Unito 6.213
CN - Cina 5.677
SG - Singapore 2.773
UA - Ucraina 2.771
IT - Italia 1.787
SE - Svezia 1.653
TR - Turchia 1.133
DE - Germania 1.062
RU - Federazione Russa 944
FI - Finlandia 942
IE - Irlanda 597
FR - Francia 586
BR - Brasile 525
VN - Vietnam 406
CA - Canada 197
IN - India 194
JP - Giappone 132
BE - Belgio 114
PL - Polonia 105
EU - Europa 80
HK - Hong Kong 65
AR - Argentina 64
AT - Austria 61
ES - Italia 61
KR - Corea 55
BD - Bangladesh 54
IQ - Iraq 48
RO - Romania 44
MX - Messico 42
KE - Kenya 37
ZA - Sudafrica 36
AU - Australia 28
ID - Indonesia 26
PK - Pakistan 26
CH - Svizzera 25
CO - Colombia 22
CL - Cile 21
SA - Arabia Saudita 21
LT - Lituania 20
IR - Iran 18
EC - Ecuador 16
TG - Togo 16
MA - Marocco 14
VE - Venezuela 14
AL - Albania 13
PH - Filippine 13
PE - Perù 12
PY - Paraguay 11
JO - Giordania 10
NP - Nepal 10
AE - Emirati Arabi Uniti 9
EE - Estonia 9
GR - Grecia 9
HU - Ungheria 9
NZ - Nuova Zelanda 9
UZ - Uzbekistan 9
AZ - Azerbaigian 8
DK - Danimarca 8
IL - Israele 8
DZ - Algeria 7
JM - Giamaica 7
EG - Egitto 6
ET - Etiopia 6
KG - Kirghizistan 6
KZ - Kazakistan 6
LA - Repubblica Popolare Democratica del Laos 6
PT - Portogallo 6
AM - Armenia 5
BG - Bulgaria 5
BO - Bolivia 5
HN - Honduras 5
HR - Croazia 5
LU - Lussemburgo 5
LV - Lettonia 5
MD - Moldavia 5
OM - Oman 5
RS - Serbia 5
SM - San Marino 5
TN - Tunisia 5
TW - Taiwan 5
UY - Uruguay 5
CR - Costa Rica 4
CZ - Repubblica Ceca 4
LB - Libano 4
SI - Slovenia 4
SK - Slovacchia (Repubblica Slovacca) 4
A2 - ???statistics.table.value.countryCode.A2??? 3
BY - Bielorussia 3
CI - Costa d'Avorio 3
DO - Repubblica Dominicana 3
GE - Georgia 3
IS - Islanda 3
KW - Kuwait 3
MY - Malesia 3
NO - Norvegia 3
PA - Panama 3
AO - Angola 2
BB - Barbados 2
Totale 67.635
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Città #
Amsterdam 9.481
Southend 5.676
Dallas 4.179
Woodbridge 3.099
Ann Arbor 2.232
Jacksonville 2.211
Houston 2.130
Ashburn 1.940
Chandler 1.869
Fairfield 1.852
Singapore 1.447
San Jose 1.234
Nanjing 1.223
Cambridge 895
Izmir 876
Wilmington 826
Beijing 723
Seattle 715
Dublin 538
Boardman 493
Nanchang 465
Helsinki 381
San Mateo 345
Princeton 317
New York 294
Lauterbourg 282
Düsseldorf 255
Hebei 249
Shenyang 242
Tianjin 220
Los Angeles 219
Changsha 199
Jiaxing 186
Kunming 162
Moscow 158
Istanbul 147
Munich 136
Des Moines 133
Velikiy Novgorod 125
Ho Chi Minh City 119
Brussels 112
Shanghai 108
Santa Clara 107
Mülheim 93
Hanoi 92
Toronto 90
San Diego 85
Urbino 83
Bremen 81
San Francisco 81
Jinan 79
Council Bluffs 77
Hangzhou 77
Buffalo 74
Milan 74
Guangzhou 73
Frankfurt am Main 68
London 67
Orem 67
Orciano Di Pesaro 61
Lanzhou 59
Zhengzhou 58
Changchun 57
Venice 57
Dong Ket 54
Ningbo 53
Nuremberg 52
Stockholm 52
Warsaw 52
São Paulo 50
Tokyo 50
Hong Kong 49
Menlo Park 48
Seongnam 45
Chicago 44
Montreal 44
Rome 44
Vienna 42
Dearborn 41
Kraków 40
Turku 38
Norwalk 37
Haikou 36
Brooklyn 34
Chennai 34
Shenzhen 34
Denver 32
Phoenix 28
Johannesburg 27
Secaucus 27
Taizhou 27
Manchester 26
Wuppertal 26
Auburn Hills 25
Nairobi 24
Rio de Janeiro 24
Augusta 23
The Dalles 23
Fuzhou 22
Mumbai 22
Totale 51.482
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Nome #
1-(2-Alkylamidoethyl)-6-methoxyindole Derivatives: A New Class of Potent Indole Melatonin Analogues. 3.179
1-Aminocyclopropane-1-carboxylic acid derivatives as ligands at the glicine-site of the NMDA receptor. 3.172
1,7-DIHYDROPYRROLO[3,4-e][1,4]DIAZEPIN-2(3H)-ONE DERIVATIVES, AND THEIR USE AS ANTICONVULSANT AND ANTIANXIETY AGENTS 3.140
1,5-BENZODIAZEPINE-2,4-DIONE GASTRIN AND CHOLECYSTOKININ-B-RECEPTOR ANTAGONISTS 3.135
SULLA MICELIANAMMIDE 2.100
Inibitori dell’enzima NAAA (N-Acylethanolamine-Hydrolizing Acid Amidase) come nuovi agenti antinfiammatori 865
1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES AS LIGANDS AT THE GLYCINE-BINDING SITE OF THE N-METHYL-D-ASPARTATE RECEPTOR 429
Scoperta del primo inibitore dell’enzima idrolasi delle ammidi degli acidi grassi (FAAH) ad azione periferica 350
Towards the development of 5-HT7 ligands combining serotonin-like and arylpiperazine moieties 302
Divergent synthesis of novel 9-deazaxanthine derivatives via late-stage cross-coupling reactions 288
ORGANIC REACTIONS OF FLUOROXY COMPOUNDS: ADDITION REACTIONS OF UNACTIVATED AND DEACTIVATED UNSATURATED LINKAGES OF STEROIDS 284
Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress 281
A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo 277
(E)-3-(2-(N-phenylcarbamoyl)vinyl)pyrrole-2-carboxylic acid derivatives. A novel class of glycine site antagonists. 275
Sintesi e studi di relazione struttura-attività/stabilità di carbammati inibitori dell’enzima FAAH 275
3-(2-Carbamoylvinyl)-4,5-dimethylpyrrole-2-carboxylic acids as ligands at the NMDA glycine-binding site: a study on the 2-carbamoylvinyl chain modification 274
Synthesis and Biological Activity of new melatonin dimeric derivatives. 272
2-n-Butyl- 9-methyl-8-(1,2,3)triazol-2-yl-9H-purin-6-ylamine and Analogues as A2A Adenosine Receptor Antagonists. Design, Synthesis, and Pharmacological Characterization 272
A new melatonin receptor ligand with mt1-agonist and MT2-antagonist properties 272
Tricyclic Alkylamides as Melatonin Receptor Ligands with Antagonist or Inverse Agonist Activity 270
4,5-Dihydroisoxazole and 4,5-dihydro-1,2,4-oxadiazole derivatives from cycloaddition reactions of nitrile oxides to alkyl N-(diphenylmethylene)-α ,β -dehydroamino acids 268
Potent, Metabolically Stable 2-Alkyl-8-(2H-1,2,3-triazol-2-yl)-9H-adenines as Adenosine A2A Receptor Ligands 268
Structure–Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability 268
ENOLATES OF 17,20:20,21-BISMETHYLENEDIOXYPREDNISONE 266
Alkyl 2 (Diphenyl-methyleneamino) acrylates in the Synthesis of α-Amino Acids 265
An improved route to cycloalka[b]pyrrole 2-carboxylates 262
Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability 261
Synthesis of benzo[1,2-d;3,4-d’]diimidazole and 1H-pyrazolo[4,3-b]pyridine as putative A2A receptor antagonists 260
5-(2-Ethyl-phenyl)-3-(3-methoxy-phenyl)-1H-[1,2,4]triazole (DL-111-IT ) and related compounds induce morphological apoptotic patterns in cultures of human tumor cell lines 254
Synthesis and Biological Evaluation of Metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), A Potent Antagonist of the A2AAdenosine Receptor for the Treatment of Parkinson’s Disease 252
Identification of a Bioactive Impurity in a Commercial Sample of 6-Methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754) 251
Reassessing the melatonin pharmacophore: enantiomeric resolution, pharmacological activity, structure analysis, and molecular modeling of a constrained chiral melatonin analogue. 251
10-(1-HYDROXYMETHYL)-11-OXO-1-AZATRICYCLOUNDEC-2-ENE-2-CARBOXYLIC ACID ESTERS USEFUL AS ANTIBACTERIAL AND PROCESS FOR THEIR PREPARATION 249
"Hot spots" in Medicinal Chemistry 244
2,4,5-TRISUBSTITUTED OXAZOLES 243
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis 242
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation 240
2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists 240
N (Diphenylmethylene)-α,β−didehydroamino Acid Esters. Thermal and Lewis Acid Induced Dimerizations 234
Application of a non-electrophysiological method to study binding affinity and efficacy of glicine analogs to the glicine site of the NMDA receptor-ion channel complex. 233
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 233
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 232
POSITIVE ION-MASS SPECTRA AND COLLISION-INDUCED DISSOCIATION OF SOME 2,3-DIDEHYDRO AMINO ACIDS 231
Modulation of Anxiety Through Blockade of Anandamide Hydrolysis 230
Anandamide suppressess pain initiation through a peripheral endocannabinoid mechanism 228
2,3-Dehydroamino acid derivatives as intermediates in the synthesis of heterocyclic compounds. 227
5-halo-tryptamine derivatives used as ligands of the 5-ht6 and/or 5-ht7 serotonin receptors, preparation, and therapeutic use.. 223
N-(Substituted-anilinoethyl)acylamides: Design, Synthesis and Pharmacological Characterization of a New Class of Melatonin Receptor Ligands 221
An endocannabinoid mechanism for stress-induced analgesia 219
TEICOPLANIN HYDRAZIDES AS ANTIBACTERIALS 219
N-(Anilinoethyl)amides: design and synthesis of metabolically stable, selective melatonin receptor ligands. 219
Design and synthesis of N-[3,3-diphenyl-propenyl]alkanamides as a novel class of potent MT2-selective Melatonin receptor ligands 218
(E)-3-[2-(Carbamoylvinyl)]pyrrol-2-carboxylic acid derivatives: A novel Class of glycine site Antagonists. 218
2,4-Dicarboxy-pyrroles as Selective Non-Competitive mGluR1 Antagonists: an exploration of the role of the pyrrolic scaffold 217
Bivalent Ligand Approach on N-[2-[(3-methoxyphenyl)methylamino]ethyl]acetamide. Synthesis, Binding Affinity and Intrinsic Acivity for MT(1) and MT(2) melatonin Receptors. 217
Toward the Definition of Stereochemical Requirements for MT(2)-Selective Antagonists and Partial Agonists by Studying 4-Phenyl-2-propionamidotetralin Derivatives 217
3,6-DISUBSTITUTED TRIAZOLO[3,4-a]PHTHALAZINE DERIVATIVES 215
Mechanisms of action and antiproliferative properties of URB631 in human breast cancer 215
O-Biphenyl-3-yl Carbamates as Peripheral FAAH Inhibitors: Synthesis and Structure–Activity (SAR) Relationship Studies 214
Peripherally Restricted FAAH Inhibitors 214
N-(DIPHENYLMETHYLENE)-ALPHA,BETA-DIDEHYDROAMINO ACID ESTERS. THERMAL AND LEWIS ACID INDUCED DIMERIZATIONS 212
2,3-Dihydro-6,7-dichloro-pyrido[2,3-b]pyrazine-8-oxide as Selective Glycine Antagonist with in vivo Activity. 211
Synthesis and Structure–Activity Relationships of a Series of Pyrrole Cannabinoid Receptor Agonists 211
Conformationally Restrained Melatonin Analogs: Synthesis, Binding Affinity for the Melatonin Receptor, Evaluation of the Biological Activity, and Molecular Modeling Study 211
Synthesis and Structure–Activity Relationship (SAR) of 2-Methyl-4-oxo-3-oxetanyl Carbamic Acid Esters, a Class of Potent N-Acylethanolamine Acid Amidase (NAAA) Inhibitors 211
Differentiation between isomeric 1-aminocyclopropane-1-carboxylic acid derivatives by means of chemical ionisation and mass selected collision induced dissociation 210
N-acetiltriptamine 2,5-sostituite: sintesi e valutazione dell’attività biologica per i recettori melatoninergici MT1 e MT2 210
X-RAY STRUCTURE DETERMINATION OF MEXIPROSTIL, A NEW GASTROPROTECTIVE 16-METHOXY-16METHYL-PGE1 ANALOGUE 208
N-Acyl-5- and -2,5-substituted tryptamines: synthesis, activity and affinity for human mt1 and MT2 melatonin receptors 208
Plant-derived phenolic compounds prevent the DNA single-strand breakage and cytotoxicity induced by tert-butylhydroperoxide via an iron-chelating mechanism. 207
Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand 207
2-N-Acylaminoalkylindoles: Design and Quantitative Structure-Activity Relationship Studies Leading to MT2-Selective Antagonists. 206
Synthesis, Enantiomeric Resolution and Structure-Activity Relationship Study for a Series of 10,11-Dihydro-5H-dibenzo[a,d]cycloheptene MT2 Receptor Antagonists. 205
Synthesis of (E)-8-(3-Chlorostyryl)caffeine Analogues Leading to 9-Deazaxanthine Derivatives as Dual A2AAntagonists/MAO-B Inhibitors 205
(2-AMINOETHYL)IMIDAZOLES.SYNTHESIS OF 1,4-DIMETHYL-5-PHENYL-2-[2-(4-PHENYLPIPERAZINYL)ETHYL]IMIDAZOLE 204
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 203
Sintesi e studi biologici preliminari su analoghi di URB937, il primo inibitore ad azione periferica dell'enzima FAAH 202
Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain 202
Endocannabinoids in the Treatment of Mood Disorders: Evidence from Animal Models 201
The Fatty Acid Amide Hydrolase Inhibitor URB597 (Cyclohexylcarbamic Acid 3’-Carbamoylbiphenyl-3-yl Ester) Reduces Neuropathic Pain after Oral Administration in Mice 200
GENERALISED ELECTROPHILIC FLUORINATION BY FLUOROXY COMPOUNDS 200
MELATONIN RECEPTOR AGONISTS: SAR AND APPLICATIONS TO THE TREATMENT OF SLEEP-WAKE DISORDERS 198
2 - Arachidonoylglycerol and anandamide are endocannabinoid mediators of stress - induced analgesia 198
Alchilammidi tricicliche: legandi selettivi dei recettori melatoninergici MT1 e MT2 198
SYNTHESIS, BINDING AFFINITY FOR THE MELATONIN RECEPTOR, AND EVALUATION OF THE BIOLOGICAL ACTIVITY OF NEW INDOLE-BASED MELATONIN ANALOGUES. 196
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 195
Modulation of anxiety through blockade of anandamide hydrolysis 193
SUITABILITY OF FAST-ION BOMBARDMENT MASS SPECTROMETRY FOR THE INVESTIGATION OF 11,4-DIHYDROPYRIDINE DERIVATIVES 192
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus 192
URB602 Inhibits Monoacylglycerol Lipase and Selectively Blocks 2-Arachidonoylglycerol Degradation in Intact Brain Slices 191
SYNTHESIS AND BIOLOGICAL PROPERTIES OF N63-CARBOXAMIDES OF TEICOPLANIN ANTIBIOTICS. STRUCTURE-ACTIVITY RELATIONSHIPS. 191
Pharmacological characterization of hydrolysis resistano analogs of oleoylethanolamide with potent anorexiant properties 190
ANGIOTENSIN CONVERTING ENZYME INHIBITORS AS ANTIHYPERTENSIVE AGENTS: 1-[´2-MERCAPTOCYCLOALKYL`CARBONYL]-L-PROLINES 190
UNIVERSITY EDUCATION OF MEDICINAL CHEMISTS: COMPARISON OF EIGHT COUNTRIES 189
2-(1,1'-BIPHEN-4-YL)-1,2,4-TRIAZOLE[5,1-a]ISOQUINOLINE (L-14105), A POTENTIAL ORALLY ACTIVE CONTRAGESTATIONAL AGENT FOR THE BITCH: STUDIES IN THE RAT, HAMSTER AND DOG 189
N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis, Structure–Activity and Structure–Property Relationships 189
Melatonin prevents apoptosis induced by UV-B treatment in U937 cell line. 188
Metastable ion studies in the characterization melatonin isomers 188
2-n-butyl-9-methyl-8-(1,2,3)triazol-2yl-9H-purin-6-yl-amine (ST 1535) and analogs as A2a Adenosine receptor antagonists. Design, synthesis and pharmacological characterization 188
Application of 3D-QSAR in the Rational Design of Receptor Ligands and Enzyme Inhibitors 188
Totale 37.167
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Categoria #
all - tutte 191.799
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 191.799
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.488 0 0 0 0 0 0 0 0 0 425 743 320
2021/20223.235 188 375 398 514 74 84 111 202 219 136 41 893
2022/20235.271 613 291 153 643 460 1.157 15 428 868 137 354 152
2023/20241.271 165 132 78 157 81 294 65 80 19 88 22 90
2024/20254.519 285 248 1.123 275 98 424 452 305 369 254 376 310
2025/202621.960 769 2.014 3.712 1.659 789 808 1.428 354 10.008 419 0 0
Totale 67.954