IRIS
TARZIA, GIORGIO
 Distribuzione geografica
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Continente #
NA - Nord America 20.674
EU - Europa 15.047
AS - Asia 5.137
Continente sconosciuto - Info sul continente non disponibili 83
SA - Sud America 34
OC - Oceania 29
AF - Africa 25
AN - Antartide 1
Totale 41.030
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Nazione #
US - Stati Uniti d'America 20.559
GB - Regno Unito 6.095
CN - Cina 3.795
UA - Ucraina 2.750
SE - Svezia 1.605
IT - Italia 1.571
TR - Turchia 892
FI - Finlandia 835
DE - Germania 824
IE - Irlanda 590
FR - Francia 241
RU - Federazione Russa 170
IN - India 107
CA - Canada 104
BE - Belgio 96
JP - Giappone 89
EU - Europa 80
VN - Vietnam 64
SG - Singapore 59
PL - Polonia 49
KR - Corea 48
RO - Romania 41
AT - Austria 32
NL - Olanda 27
AU - Australia 25
CH - Svizzera 24
ES - Italia 22
HK - Hong Kong 16
IR - Iran 16
TG - Togo 16
BR - Brasile 12
ID - Indonesia 10
CL - Cile 9
HU - Ungheria 9
AL - Albania 8
MX - Messico 8
GR - Grecia 7
DK - Danimarca 6
SA - Arabia Saudita 6
EE - Estonia 5
HR - Croazia 5
AM - Armenia 4
BD - Bangladesh 4
BG - Bulgaria 4
IQ - Iraq 4
LA - Repubblica Popolare Democratica del Laos 4
LU - Lussemburgo 4
MA - Marocco 4
NZ - Nuova Zelanda 4
PE - Perù 4
PK - Pakistan 4
RS - Serbia 4
SI - Slovenia 4
A2 - ???statistics.table.value.countryCode.A2??? 3
CO - Colombia 3
IL - Israele 3
LB - Libano 3
PT - Portogallo 3
SK - Slovacchia (Repubblica Slovacca) 3
ZA - Sudafrica 3
AR - Argentina 2
BO - Bolivia 2
BY - Bielorussia 2
FK - Isole Falkland (Malvinas) 2
JM - Giamaica 2
MD - Moldavia 2
NO - Norvegia 2
PH - Filippine 2
SL - Sierra Leone 2
TW - Taiwan 2
AE - Emirati Arabi Uniti 1
CZ - Repubblica Ceca 1
GS - Georgia del Sud e Isole Sandwich Australi 1
IM - Isola di Man 1
IS - Islanda 1
KW - Kuwait 1
LK - Sri Lanka 1
LT - Lituania 1
LV - Lettonia 1
ME - Montenegro 1
MO - Macao, regione amministrativa speciale della Cina 1
MY - Malesia 1
PA - Panama 1
SM - San Marino 1
Totale 41.030
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Città #
Southend 5.676
Woodbridge 3.099
Ann Arbor 2.232
Jacksonville 2.211
Houston 2.108
Chandler 1.869
Fairfield 1.852
Nanjing 1.217
Ashburn 1.020
Cambridge 895
Izmir 876
Wilmington 826
Seattle 709
Dublin 532
Nanchang 465
San Mateo 345
Princeton 317
Helsinki 312
Beijing 296
Hebei 249
Shenyang 242
Düsseldorf 226
Tianjin 210
Changsha 193
New York 192
Jiaxing 170
Kunming 162
Boardman 143
Velikiy Novgorod 125
Brussels 94
Mülheim 93
San Diego 84
Des Moines 83
Bremen 81
Urbino 80
Jinan 75
Hangzhou 69
San Francisco 69
Toronto 67
Orciano Di Pesaro 61
Lanzhou 59
Venice 56
Changchun 54
Dong Ket 54
Zhengzhou 54
Ningbo 53
Menlo Park 48
Milan 47
Seongnam 45
Shanghai 44
Dearborn 41
Munich 41
Kraków 40
Norwalk 37
Haikou 35
London 35
Vienna 32
Wuppertal 26
Auburn Hills 25
Los Angeles 25
Rome 25
Guangzhou 21
Leawood 21
Parma 21
Fuzhou 20
Taizhou 20
West Jordan 20
Redwood City 19
Ancona 18
Augusta 18
Timisoara 18
Florence 17
Lomé 16
Singapore 16
Borås 15
Edinburgh 14
Frankfurt am Main 14
Hefei 14
Mcallen 14
Orange 14
Cava De' Tirreni 13
Focsani 13
Melbourne 13
Portland 13
Mumbai 12
Dormagen 11
Napoli 11
Padova 11
Palermo 11
Amsterdam 10
Ardabil 10
Chicago 10
Hanoi 10
Scottsdale 10
Bologna 9
Hanover 9
Tokyo 9
Andover 8
Berlin 8
Messina 8
Totale 31.040
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Nome #
Inibitori dell’enzima NAAA (N-Acylethanolamine-Hydrolizing Acid Amidase) come nuovi agenti antinfiammatori 720
1,5-BENZODIAZEPINE-2,4-DIONE GASTRIN AND CHOLECYSTOKININ-B-RECEPTOR ANTAGONISTS 304
1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES AS LIGANDS AT THE GLYCINE-BINDING SITE OF THE N-METHYL-D-ASPARTATE RECEPTOR 300
1-(2-Alkylamidoethyl)-6-methoxyindole Derivatives: A New Class of Potent Indole Melatonin Analogues. 297
1,7-DIHYDROPYRROLO[3,4-e][1,4]DIAZEPIN-2(3H)-ONE DERIVATIVES, AND THEIR USE AS ANTICONVULSANT AND ANTIANXIETY AGENTS 286
1-Aminocyclopropane-1-carboxylic acid derivatives as ligands at the glicine-site of the NMDA receptor. 284
ORGANIC REACTIONS OF FLUOROXY COMPOUNDS: ADDITION REACTIONS OF UNACTIVATED AND DEACTIVATED UNSATURATED LINKAGES OF STEROIDS 249
ENOLATES OF 17,20:20,21-BISMETHYLENEDIOXYPREDNISONE 236
Scoperta del primo inibitore dell’enzima idrolasi delle ammidi degli acidi grassi (FAAH) ad azione periferica 233
Towards the development of 5-HT7 ligands combining serotonin-like and arylpiperazine moieties 229
Potent, Metabolically Stable 2-Alkyl-8-(2H-1,2,3-triazol-2-yl)-9H-adenines as Adenosine A2A Receptor Ligands 228
Divergent synthesis of novel 9-deazaxanthine derivatives via late-stage cross-coupling reactions 224
Tricyclic Alkylamides as Melatonin Receptor Ligands with Antagonist or Inverse Agonist Activity 222
Synthesis of benzo[1,2-d;3,4-d’]diimidazole and 1H-pyrazolo[4,3-b]pyridine as putative A2A receptor antagonists 217
Structure–Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability 213
2-n-Butyl- 9-methyl-8-(1,2,3)triazol-2-yl-9H-purin-6-ylamine and Analogues as A2A Adenosine Receptor Antagonists. Design, Synthesis, and Pharmacological Characterization 209
Synthesis and Biological Evaluation of Metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), A Potent Antagonist of the A2AAdenosine Receptor for the Treatment of Parkinson’s Disease 208
A new melatonin receptor ligand with mt1-agonist and MT2-antagonist properties 205
Synthesis and Biological Activity of new melatonin dimeric derivatives. 204
Alkyl 2 (Diphenyl-methyleneamino) acrylates in the Synthesis of α-Amino Acids 204
Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability 202
Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress 199
POSITIVE ION-MASS SPECTRA AND COLLISION-INDUCED DISSOCIATION OF SOME 2,3-DIDEHYDRO AMINO ACIDS 197
Modulation of Anxiety Through Blockade of Anandamide Hydrolysis 197
Sintesi e studi di relazione struttura-attività/stabilità di carbammati inibitori dell’enzima FAAH 197
(E)-3-(2-(N-phenylcarbamoyl)vinyl)pyrrole-2-carboxylic acid derivatives. A novel class of glycine site antagonists. 195
A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo 193
Identification of a Bioactive Impurity in a Commercial Sample of 6-Methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754) 190
4,5-Dihydroisoxazole and 4,5-dihydro-1,2,4-oxadiazole derivatives from cycloaddition reactions of nitrile oxides to alkyl N-(diphenylmethylene)-α ,β -dehydroamino acids 189
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 187
An improved route to cycloalka[b]pyrrole 2-carboxylates 185
TEICOPLANIN HYDRAZIDES AS ANTIBACTERIALS 184
3-(2-Carbamoylvinyl)-4,5-dimethylpyrrole-2-carboxylic acids as ligands at the NMDA glycine-binding site: a study on the 2-carbamoylvinyl chain modification 183
Toward the Definition of Stereochemical Requirements for MT(2)-Selective Antagonists and Partial Agonists by Studying 4-Phenyl-2-propionamidotetralin Derivatives 182
3,6-DISUBSTITUTED TRIAZOLO[3,4-a]PHTHALAZINE DERIVATIVES 181
N-(Anilinoethyl)amides: design and synthesis of metabolically stable, selective melatonin receptor ligands. 179
Synthesis and Structure–Activity Relationships of a Series of Pyrrole Cannabinoid Receptor Agonists 178
2,4,5-TRISUBSTITUTED OXAZOLES 176
10-(1-HYDROXYMETHYL)-11-OXO-1-AZATRICYCLOUNDEC-2-ENE-2-CARBOXYLIC ACID ESTERS USEFUL AS ANTIBACTERIAL AND PROCESS FOR THEIR PREPARATION 175
Differentiation between isomeric 1-aminocyclopropane-1-carboxylic acid derivatives by means of chemical ionisation and mass selected collision induced dissociation 174
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation 174
Endocannabinoids in the Treatment of Mood Disorders: Evidence from Animal Models 174
Synthesis of (E)-8-(3-Chlorostyryl)caffeine Analogues Leading to 9-Deazaxanthine Derivatives as Dual A2AAntagonists/MAO-B Inhibitors 173
Peripherally Restricted FAAH Inhibitors 173
N (Diphenylmethylene)-α,β−didehydroamino Acid Esters. Thermal and Lewis Acid Induced Dimerizations 173
Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand 172
GENERALISED ELECTROPHILIC FLUORINATION BY FLUOROXY COMPOUNDS 172
Synthesis and Structure–Activity Relationship (SAR) of 2-Methyl-4-oxo-3-oxetanyl Carbamic Acid Esters, a Class of Potent N-Acylethanolamine Acid Amidase (NAAA) Inhibitors 171
Plant-derived phenolic compounds prevent the DNA single-strand breakage and cytotoxicity induced by tert-butylhydroperoxide via an iron-chelating mechanism. 170
"Hot spots" in Medicinal Chemistry 169
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 168
X-RAY STRUCTURE DETERMINATION OF MEXIPROSTIL, A NEW GASTROPROTECTIVE 16-METHOXY-16METHYL-PGE1 ANALOGUE 167
Synthesis, Enantiomeric Resolution and Structure-Activity Relationship Study for a Series of 10,11-Dihydro-5H-dibenzo[a,d]cycloheptene MT2 Receptor Antagonists. 167
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 167
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis 165
Mechanisms of action and antiproliferative properties of URB631 in human breast cancer 165
MELATONIN RECEPTOR AGONISTS: SAR AND APPLICATIONS TO THE TREATMENT OF SLEEP-WAKE DISORDERS 164
SYNTHESIS AND BIOLOGICAL PROPERTIES OF N63-CARBOXAMIDES OF TEICOPLANIN ANTIBIOTICS. STRUCTURE-ACTIVITY RELATIONSHIPS. 164
5-(2-Ethyl-phenyl)-3-(3-methoxy-phenyl)-1H-[1,2,4]triazole (DL-111-IT ) and related compounds induce morphological apoptotic patterns in cultures of human tumor cell lines 164
Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain 164
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 162
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 161
UNIVERSITY EDUCATION OF MEDICINAL CHEMISTS: COMPARISON OF EIGHT COUNTRIES 160
Application of 3D-QSAR in the Rational Design of Receptor Ligands and Enzyme Inhibitors 160
URB602 Inhibits Monoacylglycerol Lipase and Selectively Blocks 2-Arachidonoylglycerol Degradation in Intact Brain Slices 159
5-halo-tryptamine derivatives used as ligands of the 5-ht6 and/or 5-ht7 serotonin receptors, preparation, and therapeutic use.. 159
The Fatty Acid Amide Hydrolase Inhibitor URB597 (Cyclohexylcarbamic Acid 3’-Carbamoylbiphenyl-3-yl Ester) Reduces Neuropathic Pain after Oral Administration in Mice 159
ANGIOTENSIN CONVERTING ENZYME INHIBITORS AS ANTIHYPERTENSIVE AGENTS: 1-[´2-MERCAPTOCYCLOALKYL`CARBONYL]-L-PROLINES 157
SULLA MICELIANAMMIDE 157
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 157
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus 155
Reassessing the melatonin pharmacophore: enantiomeric resolution, pharmacological activity, structure analysis, and molecular modeling of a constrained chiral melatonin analogue. 155
DEAMINOTEICOPLANIN AND ITS DERIVATIVES. SYNTHESIS, ANTIBACTERIAL ACTIVITY, AND BINDING STRENGTH TO Ac-D-ALA-D-ALA 154
6-(ALKYLAMINO)-3-ARYL-1,2,4-TRIAZOLO[3,4-A]PHTHALAZINES. A NEW CLASS OF BENZODIAZEPINE RECEPTOR LIGANDS 154
The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues 154
SUITABILITY OF FAST-ION BOMBARDMENT MASS SPECTROMETRY FOR THE INVESTIGATION OF 11,4-DIHYDROPYRIDINE DERIVATIVES 153
Design and synthesis of N-[3,3-diphenyl-propenyl]alkanamides as a novel class of potent MT2-selective Melatonin receptor ligands 152
Electron Impact Ionization and Fast Atom Bombardment Mass Spectrometry of Some 3,3-Dimethyl-1-(Isoxazol-3-yl)-triazenes. A New Class of Potential Anticancer Agents. 152
Bivalent Ligand Approach on N-[2-[(3-methoxyphenyl)methylamino]ethyl]acetamide. Synthesis, Binding Affinity and Intrinsic Acivity for MT(1) and MT(2) melatonin Receptors. 152
Modulation of anxiety through blockade of anandamide hydrolysis 152
Conformationally Restrained Melatonin Analogs: Synthesis, Binding Affinity for the Melatonin Receptor, Evaluation of the Biological Activity, and Molecular Modeling Study 151
Melatonin prevents apoptosis induced by UV-B treatment in U937 cell line. 150
STRUCTURE-AFFINITY RELATIONSHIPS OF INDOLE-BASED MELATONIN ANALOGS 150
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice 150
2,3-Dehydroamino acid derivatives as intermediates in the synthesis of heterocyclic compounds. 150
Metastable ion studies in the characterization melatonin isomers 149
Sintesi e studi biologici preliminari su analoghi di URB937, il primo inibitore ad azione periferica dell'enzima FAAH 149
O-Biphenyl-3-yl Carbamates as Peripheral FAAH Inhibitors: Synthesis and Structure–Activity (SAR) Relationship Studies 149
Derivati 2-Acilamminoalchilindolici come Antagonisti/Agonisti Parziali della Melatonina 149
METABOLIC PATHWAYS OF THE ANTIHYPERTENSIVE AGENT, N-(2,5-DIMETHYL-1H-PYRROL-1-YL)-6-(4-MORPHOLINYL)-3-PYRIDAZINAMINE HYDROCHLORIDE. II.STUDIES IN THE DOG 148
Recent advances in the development of melatonin MT1 and MT2 receptor agonists 148
PYRROLOPYRIDINE ANALOGS OF NALIDIXIC ACID. 2. PYRROLO[3,4-b]PYRIDINES 148
N-(DIPHENYLMETHYLENE)-ALPHA,BETA-DIDEHYDROAMINO ACID ESTERS. THERMAL AND LEWIS ACID INDUCED DIMERIZATIONS 146
SYNTHESIS OF BETA-AMINOPYRROLES 146
An endocannabinoid mechanism for stress-induced analgesia 146
Melatonin receptor ligands: synthesis of new melatonin derivatives and comprehensive comparative molecular field analysis (CoMFA) study. 145
2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists 145
Comparison of KeV and eV Collision-induced Dissociation of Some Protonated Isomeric Cyclopropane Derivatives 144
THREE-DIMENSIONAL QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP STUDIES ON SELECTED MT1 AND MT2 MELATONIN RECEPTOR LIGANDS: REQUIREMENTS FOR SUBTYPE SELECTIVITY AND INTRINSIC ACTIVITY MODULATION 143
Reactions of 3-Carbomethoxy-2-aza-1,3-Butadiene Derivatives with Dienophiles 143
Totale 18.464
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Categoria #
all - tutte 104.176
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 104.176
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20192.254 0 0 0 0 0 0 0 0 0 234 474 1.546
2019/20207.805 1.951 275 436 1.577 276 626 562 616 315 522 255 394
2020/20214.711 133 401 155 592 237 371 263 371 700 425 743 320
2021/20223.235 188 375 398 514 74 84 111 202 219 136 41 893
2022/20235.271 613 291 153 643 460 1.157 15 428 868 137 354 152
2023/20241.108 165 132 78 157 81 294 65 80 19 37 0 0
Totale 41.312