A novel, cost-effective, and efficient process for the synthesis of 1,7-dimethyl-1,4,7,10-tetraazacyclododecane has been developed. The two-step process involved the selective conversion of commercially available cyclen to N1,N7-diethylcarbamate cyclen 3 that afforded the title compound in high yield after the reduction step.

Short and straightforward synthesis of 1,7-dimethyl-1,4,7,10-tetraazacyclododecane

FUSI, VIERI;GIORGI, LUCA;PIERSANTI, GIOVANNI;ZAPPIA, GIOVANNI
2010

Abstract

A novel, cost-effective, and efficient process for the synthesis of 1,7-dimethyl-1,4,7,10-tetraazacyclododecane has been developed. The two-step process involved the selective conversion of commercially available cyclen to N1,N7-diethylcarbamate cyclen 3 that afforded the title compound in high yield after the reduction step.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11576/2303324
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