Functionalized and substituted bis(indolyl)alkanes were synthesized from indoles and dehydroalanine esters in the presence of catalytic amounts of Brønsted acid. When 2- or 4-bulky substituted indoles were used, unusual elimination occurred to yield interesting indolyl acrylates.

Organocatalyzed coupling of indoles with dehydroalanine esters: synthesis of bis(indolyl)propanoates and indolacrylates

LUCARINI, SIMONE;MARI, MICHELE;PIERSANTI, GIOVANNI;SPADONI, GILBERTO
2013

Abstract

Functionalized and substituted bis(indolyl)alkanes were synthesized from indoles and dehydroalanine esters in the presence of catalytic amounts of Brønsted acid. When 2- or 4-bulky substituted indoles were used, unusual elimination occurred to yield interesting indolyl acrylates.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11576/2572575
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