Epidemiological evidence shows that physical activity lowers the risk of developing breast cancer and decreases the risk of disease recurrence. The main hypothesis on the positive effects of exercise-oncology has focused on lowering the basal systemic levels of cancer risk factors with exercise training. Recently, the effects of cancer progression control by components released after acute exercise bouts have gained attention. However, the evaluation of the antiproliferative potential of a single exercise bout needs technical improvement. Here, we present data of a pilot study showing how to evaluate the anti-cancer potential of single exercise bouts with an in vitro three-dimensional cell growth assay, using a triple-negative breast cancer cell line cultured with exercise-conditioned serum.
A dataset on the effect of exercise-conditioned human sera in three-dimensional breast cancer cell culture
De Santi, Mauro
;Baldelli, Giulia;Lucertini, Francesco;Natalucci, Valentina;Brandi, Giorgio;Barbieri, Elena
2019
Abstract
Epidemiological evidence shows that physical activity lowers the risk of developing breast cancer and decreases the risk of disease recurrence. The main hypothesis on the positive effects of exercise-oncology has focused on lowering the basal systemic levels of cancer risk factors with exercise training. Recently, the effects of cancer progression control by components released after acute exercise bouts have gained attention. However, the evaluation of the antiproliferative potential of a single exercise bout needs technical improvement. Here, we present data of a pilot study showing how to evaluate the anti-cancer potential of single exercise bouts with an in vitro three-dimensional cell growth assay, using a triple-negative breast cancer cell line cultured with exercise-conditioned serum.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
