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Potent, Metabolically Stable 2-Alkyl-8-(2H-1,2,3-triazol-2-yl)-9H-adenines as Adenosine A2A Receptor Ligands 1-gen-2015 Pace, Silvia; Brogin, Giandomenico; Stasi, Maria Antonietta; Riccioni, Teresa; Borsini, Franco; Capocasa, Francesca; Manera, Francesco; Tallarico, Carlo; Grossi, Pietro; Vacondio, Federica; Bassi, Michele; Bartoccini, Francesca; Lucarini, Simone; Piersanti, Giovanni; Tarzia, Giorgio; Cabri, Walter; Minetti, Patrizia
Derivatizzazione one-pot di indoli per la sintesi di triptofani, pirroloindoline, bis-indoli & co 1-gen-2014 Lucarini, Simone; Piersanti, Giovanni; Duranti, Andrea; Spadoni, Gilberto
Synthesis of 2-substituted tryptophans via a C3- to C2-alkyl migration 1-gen-2014 Mari, Michele; Lucarini, Simone; Bartoccini, Francesca; Piersanti, Giovanni; Spadoni, Gilberto
Brønsted Acid-Catalyzed Bisindolization of α-amido acetals: Synthesis and Anticancer activity of bis(indolyl)ethanamino derivatives 1-gen-2014 Mari, Michele; Aurora, Tassoni; Lucarini, Simone; Fanelli, Mirco; Piersanti, Giovanni; Spadoni, Gilberto
Single-Walled Carbon Nanotubes Functionalization for the Delivery of the Water Insoluble Anticancer Agent Indole-3-Carbinol Cyclic 1-gen-2013 De Santi, Mauro; Antonelli, Antonella; Menotta, Michele; Sfara, Carla; Serafini, Sonja; Lucarini, Simone; Brandi, Giorgio; Magnani, Mauro
Single-Walled Carbon Nanotubes Functionalization for the Delivery of the Water Insoluble Anticancer Agent Indole-3-carbinol Cyclic Tetrameric Derivative CTet 1-gen-2013 DE SANTI, Mauro; Antonelli, Antonella; Menotta, Michele; Sfara, Carla; Sonja, Serafini; Lucarini, Simone; Brandi, Giorgio; Magnani, Mauro
Antitumoral activity of indole-3-carbinol cyclic tri- and tetrameric derivatives mixture in human breast cancer cells: in vitro and in vivo studies 1-gen-2013 Brandi, Giorgio; Fraternale, Alessandra; Lucarini, Simone; Paiardini, M; DE SANTI, Mauro; Cervasi, B; Paoletti, Mf; Galluzzi, Luca; Duranti, Andrea; Magnani, Mauro
Synthesis and Biological Evaluation of Metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), A Potent Antagonist of the A2AAdenosine Receptor for the Treatment of Parkinson’s Disease 1-gen-2013 Piersanti, Giovanni; Bartoccini, Francesca; Lucarini, Simone; Walter, Cabri; Maria Antonietta, Stasi; Teresa, Riccioni; Franco, Borsini; Tarzia, Giorgio; Patrizia, Minetti
Organocatalyzed coupling of indoles with dehydroalanine esters: synthesis of bis(indolyl)propanoates and indolacrylates 1-gen-2013 Lucarini, Simone; Mari, Michele; Piersanti, Giovanni; Spadoni, Gilberto
MT1-Selective Melatonin Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Dynamics Investigation of N-{[(3-O-Substituted)anilino]alkyl}amides 1-gen-2012 Rivara, S.; Pala, D.; Lodola, A.; Mor, M.; Lucini, V.; Dugnani, S.; Scaglione, F.; Bedini, Annalida; Lucarini, Simone; Tarzia, Giorgio; Spadoni, Gilberto
A Versatile Biomimetic Approach to Diindolylmethane Derivatives as Potential Anticancer Agents 1-gen-2012 Lucarini, Simone; Piersanti, Giovanni; Duranti, Andrea; Spadoni, Gilberto
Synthesis and Configuration Determination of All Enantiopure Stereoisomers of the Melatonin Receptor Ligand 4-Phenyl-2-propionamidotetralin using an Expedient Optical Resolution of 4-Phenyl-2-tetralone 1-gen-2012 Lucarini, Simone; Bartolucci, Silvia; Bedini, Annalida; Gatti, G.; Orlando, Pierfrancesco; Piersanti, Giovanni; Spadoni, Gilberto
Indole-3-carbinol (I3C) Tetrameric Derivative (CTet) Inhibits Cell Cycle Progression Inducing Overexpression of p21/cip1/waf1 and GADD45A in Breast Cancer Cell Lines 1-gen-2011 DE SANTI, Mauro; Galluzzi, Luca; Lucarini, Simone; Fanelli, Mirco; Paoletti, MARIA FILOMENA; Fraternale, Alessandra; Duranti, Andrea; Brandi, Giorgio; Magnani, Mauro
Bivalent Ligand Approach on N-[2-[(3-methoxyphenyl)methylamino]ethyl]acetamide. Synthesis, Binding Affinity and Intrinsic Acivity for MT(1) and MT(2) melatonin Receptors. 1-gen-2011 Spadoni, Gilberto; Bedini, Annalida; Orlando, Pierfrancesco; Lucarini, Simone; Tarzia, Giorgio; Mor, M.; Rivara, S.; Lucini, V.; Pannacci, M.; Scaglione, F.
The indole-3-carbinol tetrameric derivative CTet inhibits cell proliferation via overexpression of p21/CDKN1A in both estrogen receptor-positive and triple-negative breast cancer cell lines 1-gen-2011 DE SANTI, Mauro; Galluzzi, Luca; Lucarini, Simone; Paoletti, MARIA FILOMENA; Fraternale, Alessandra; Duranti, Andrea; DE MARCO, C; Fanelli, Mirco; Zaffaroni, N; Brandi, Giorgio; Magnani, Mauro
Organocatalytic synthesis of α-quaternary amino acid derivatives via aza-Friedel–Crafts alkylation of indoles with simple α-amidoacrylates 1-gen-2011 Righi, M.; Bartoccini, Francesca; Lucarini, Simone; Piersanti, Giovanni
A practical and expeditious method for the preparation of the anticancer agent 5,6,11,12,17,18,23,24-octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 1-gen-2011 Lucarini, Simone; Antonietti, Francesca; Tontini, Andrea; Mestichelli, P; Magnani, Mauro; Duranti, Andrea
Toward the Definition of Stereochemical Requirements for MT(2)-Selective Antagonists and Partial Agonists by Studying 4-Phenyl-2-propionamidotetralin Derivatives 1-gen-2011 Bedini, Annalida; Lucarini, Simone; Spadoni, Gilberto; Tarzia, Giorgio; Scaglione, F; Dugnani, S; Pannacci, M; Lucini, V; Carmi, C; Pala, D; Rivara, S; Mor, M.
Synthesis and Biological Evaluation of a γ-Cyclodextrin-based Formulation of the Anticancer Agent 5,6,11,12,17,18,23,24-Octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 1-gen-2010 Lucarini, Simone; DE SANTI, Mauro; Antonietti, Francesca; Brandi, Giorgio; Diamantini, Giuseppe; Fraternale, Alessandra; Paoletti, MARIA FILOMENA; Tontini, Andrea; Magnani, Mauro; Duranti, Andrea
New Synthesis, Biological Evaluation and Formulation Studies on the Cyclic Tetraindole Derivative CTet, an Anticancer Agent 1-gen-2010 Lucarini, Simone; DE SANTI, Mauro; Brandi, Giorgio; Magnani, Mauro; Duranti, Andrea
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