IRIS
DURANTI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 11.151
EU - Europa 7.814
AS - Asia 2.964
OC - Oceania 29
SA - Sud America 29
AF - Africa 9
Continente sconosciuto - Info sul continente non disponibili 9
Totale 22.005
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Nazione #
US - Stati Uniti d'America 11.091
GB - Regno Unito 2.530
CN - Cina 1.921
IT - Italia 1.672
UA - Ucraina 1.365
SE - Svezia 676
FI - Finlandia 502
TR - Turchia 473
DE - Germania 342
IE - Irlanda 327
SG - Singapore 292
FR - Francia 133
RU - Federazione Russa 102
IN - India 87
KR - Corea 57
CA - Canada 50
VN - Vietnam 49
PL - Polonia 45
JP - Giappone 38
AU - Australia 24
BE - Belgio 22
ES - Italia 20
BR - Brasile 15
NL - Olanda 14
IR - Iran 12
CH - Svizzera 9
AT - Austria 8
CL - Cile 8
HU - Ungheria 8
MX - Messico 8
RO - Romania 8
EU - Europa 7
HR - Croazia 7
NZ - Nuova Zelanda 5
PT - Portogallo 5
AE - Emirati Arabi Uniti 4
ID - Indonesia 4
SA - Arabia Saudita 4
BD - Bangladesh 3
CO - Colombia 3
GR - Grecia 3
HK - Hong Kong 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
EG - Egitto 2
IQ - Iraq 2
LK - Sri Lanka 2
LT - Lituania 2
LU - Lussemburgo 2
LV - Lettonia 2
MA - Marocco 2
MD - Moldavia 2
MY - Malesia 2
NG - Nigeria 2
NO - Norvegia 2
PE - Perù 2
PK - Pakistan 2
TH - Thailandia 2
TW - Taiwan 2
BA - Bosnia-Erzegovina 1
BY - Bielorussia 1
DK - Danimarca 1
DZ - Algeria 1
EE - Estonia 1
FK - Isole Falkland (Malvinas) 1
IL - Israele 1
JM - Giamaica 1
JO - Giordania 1
PA - Panama 1
PH - Filippine 1
SI - Slovenia 1
SL - Sierra Leone 1
SM - San Marino 1
ZA - Sudafrica 1
Totale 22.005
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Città #
Southend 2.316
Woodbridge 1.678
Ann Arbor 1.244
Houston 1.114
Jacksonville 1.090
Fairfield 1.052
Chandler 894
Nanjing 555
Ashburn 502
Cambridge 476
Wilmington 448
Seattle 427
Izmir 345
Dublin 269
Boardman 253
Singapore 231
Urbino 229
Helsinki 195
Nanchang 192
San Mateo 169
Beijing 167
Princeton 161
Hebei 118
Shenyang 118
New York 101
Changsha 98
Jiaxing 95
Istanbul 89
Tianjin 84
Velikiy Novgorod 82
Kunming 57
Seongnam 52
Menlo Park 48
San Diego 47
Dong Ket 46
Düsseldorf 46
Bremen 43
Milan 43
San Francisco 42
Santa Clara 40
Rome 38
Toronto 34
London 32
Mülheim 32
Jinan 31
Shanghai 31
Kraków 30
Hangzhou 29
Changchun 27
Munich 25
Ningbo 23
Lanzhou 22
Brussels 20
Guangzhou 20
Ancona 19
Napoli 19
Palermo 19
Dearborn 18
Norwalk 18
Leawood 17
Taizhou 17
Zhengzhou 17
Des Moines 16
Haikou 16
Cava De' Tirreni 15
Mumbai 15
Parma 15
Hefei 14
Augusta 13
Bologna 13
Monte Porzio 13
Redwood City 13
Shenzhen 13
Naples 12
Florence 11
Wuppertal 11
Auburn Hills 10
Padova 10
Colli Del Tronto 9
Madrid 9
Messina 9
Osimo 9
Tokyo 9
Fiorano Modenese 8
Iesi 8
Melbourne 8
Pesaro 8
Portland 8
San Benedetto del Tronto 8
Venice 8
Vienna 8
Acton 7
Ardabil 7
Bari 7
Berlin 7
Cagliari 7
Falconara Marittima 7
Frankfurt am Main 7
Jesi 7
Krefeld 7
Totale 16.176
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Nome #
Inibitori dell’enzima NAAA (N-Acylethanolamine-Hydrolizing Acid Amidase) come nuovi agenti antinfiammatori 754
Unsaturated fatty acids lactose esters: cytotoxicity, permeability enhancement and antimicrobial activity 329
Pharmacokinetics, pharmacodynamics and safety studies on URB 937, a peripherally restricted fatty acid amide hydrolase inhibitor, in rats 314
Scoperta del primo inibitore dell’enzima idrolasi delle ammidi degli acidi grassi (FAAH) ad azione periferica 245
Derivatizzazione one-pot di indoli per la sintesi di triptofani, pirroloindoline, bis-indoli & co 241
Structure–Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability 219
2-Substituted-5-Methoxy-N-acyltryptamines: Synthesis, Binding Affinity for Melatonin Receptor, and Evaluation of the Biological Activity 214
Induction of Endoplasmic Reticulum Stress Response by the Indole-3-Carbinol Cyclic Tetrameric Derivative CTet in Human Breast Cancer Cell Lines 212
A New Synthesis of 2-Substituted DL-Tryptophan Derivatives 208
Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability 207
Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress 206
Modulation of Anxiety Through Blockade of Anandamide Hydrolysis 205
Sintesi e studi di relazione struttura-attività/stabilità di carbammati inibitori dell’enzima FAAH 202
A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo 202
Identification of a Bioactive Impurity in a Commercial Sample of 6-Methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754) 197
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 194
Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats 192
Synthesis, Structure-Activity Relationships and In Vitro Toxicity Profile of Lactose-Based Fatty Acid Monoesters as Possible Drug Permeability Enhancers 192
Antitumoral activity of indole-3-carbinol cyclic tri- and tetrameric derivatives mixture in human breast cancer cells: in vitro and in vivo studies 189
Lactose oleate as new biocompatible surfactant for pharmaceutical applications 189
Synthesis and Biological Evaluation of a γ-Cyclodextrin-based Formulation of the Anticancer Agent 5,6,11,12,17,18,23,24-Octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 187
2-Bromomelatonin: Synthesis and characterization of a potent melatonin agonist 184
Synthesis and Structure–Activity Relationships of a Series of Pyrrole Cannabinoid Receptor Agonists 183
The Synthetic Cannabinoid URB447 Reduces Brain Injury and the Associated White Matter Demyelination After Hypoxia-Ischemia in Neonatal Rats 183
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation 181
Endocannabinoids in the Treatment of Mood Disorders: Evidence from Animal Models 181
The fatty acid amide hydrolase inhibitor URB597 modulates serotonin-dependent emotional behaviour, and serotonin1A and serotonin2A/C activity in the hippocampus 179
Peripherally Restricted FAAH Inhibitors 176
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis 174
Antimyotonic effects of enantiomers of mexiletine-like drugs 174
Synthesis and Structure–Activity Relationship (SAR) of 2-Methyl-4-oxo-3-oxetanyl Carbamic Acid Esters, a Class of Potent N-Acylethanolamine Acid Amidase (NAAA) Inhibitors 173
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 173
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 171
Mechanisms of action and antiproliferative properties of URB631 in human breast cancer 171
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 171
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 171
Therapeutic Effects of Tocainide and Mexiletine Analogs on Myotonic MTO and ADR Mice 170
Endocannabinoid Regulation of Acute and Protracted Nicotine Withdrawal: Effect of FAAH Inhibition 168
Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain 168
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 166
Application of 3D-QSAR in the Rational Design of Receptor Ligands and Enzyme Inhibitors 166
Synthesis and Evaluation of Saccharide-Based Aliphatic and Aromatic Esters as Antimicrobial and Antibiofilm Agents 165
The Fatty Acid Amide Hydrolase Inhibitor URB597 (Cyclohexylcarbamic Acid 3’-Carbamoylbiphenyl-3-yl Ester) Reduces Neuropathic Pain after Oral Administration in Mice 164
URB602 Inhibits Monoacylglycerol Lipase and Selectively Blocks 2-Arachidonoylglycerol Degradation in Intact Brain Slices 163
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus 162
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 162
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 162
The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues 159
O-Biphenyl-3-yl Carbamates as Peripheral FAAH Inhibitors: Synthesis and Structure–Activity (SAR) Relationship Studies 157
Modulation of anxiety through blockade of anandamide hydrolysis 157
Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors 156
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice 154
Homologation of mexiletine alkyl chain and stereoselective blockade of skeletal muscle sodium channels 153
An endocannabinoid mechanism for stress-induced analgesia 153
A practical and expeditious method for the preparation of the anticancer agent 5,6,11,12,17,18,23,24-octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 152
Sintesi e studi biologici preliminari su analoghi di URB937, il primo inibitore ad azione periferica dell'enzima FAAH 152
Indole-3-carbinol (I3C) Tetrameric Derivative (CTet) Inhibits Cell Cycle Progression Inducing Overexpression of p21/cip1/waf1 and GADD45A in Breast Cancer Cell Lines 148
Selective inhibition of 2 - AG hydrolysis enhances endocannabinoid signaling in the hippocampus 146
The indole-3-carbinol tetrameric derivative CTet inhibits cell proliferation via overexpression of p21/CDKN1A in both estrogen receptor-positive and triple-negative breast cancer cell lines 146
Pharmacological Profile of the Selective FAAH Inhibitor KDS-4103 (URB597) 144
SYNTHESIS AND EVALUATION OF SUGAR-BASED ALIPHATIC AND AROMATIC FATTY ACID ESTERS AS ANTIMICROBIAL AND ANTIBIOFILM AGENTS 142
N-alchil-O-arilcarbammati come inibitori delle idrolasi delle ammidi degli acidi grassi (FAAH): aspetti meccanicistici 141
N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis, Structure–Activity and Structure–Property Relationships 140
Contribution to the Study of 2-Aryloxy-1-phenyl and 2-Aryloxy-2-phenylethanols. Differentiation by Mass Spectrometry 139
Stereospecific synthesis of mexiletine and related compounds: Mitsunobu versus Williamson reaction 138
Synthesis and Structure–Activity Relationship Studies of O-Biphenyl-3-yl Carbamates as Peripherally Restricted Fatty Acid Amide Hydrolase Inhibitors 138
Synthesis and Structure–Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors 136
Anandamide suppressess pain initiation through a peripheral endocannabinoid mechanism 136
The CB1 Antagonist/CB2 Agonist URB447 Confers Neuroprotection after Neonatal Hypoxia-ischemia 135
Design, SAR and Biological Activity of a New Class of FAAH Inhibitors: Cyclohexyl Carbamic Acid Biphenyl-3-yl Esters 132
2-Substituted-5-Methoxy-N-acyltryptamines: Synthesis and Binding Affinity to the Melatonin Receptor 132
Characterization of the Fatty Acid Amide Hydrolase Inhibitor Cyclohexyl Carbamic Acid 3'-Carbamoyl-biphenyl-3-yl Ester (URB597): Effects on Anandamide and Oleoylethanolamide Deactivation 130
2 - Arachidonoylglycerol and anandamide are endocannabinoid mediators of stress - induced analgesia 130
α-Acylamino-β-lactones as a new class of N-acylethanolamine-hydrolyzing acid amidase (NAAA) inhibitors: synthesis and structure–activity relationships 129
A Versatile Biomimetic Approach to Diindolylmethane Derivatives as Potential Anticancer Agents 128
Identification of a Bioactive Impurity Present in a Sample of URB754 127
Synthesis and Structure-Activity/Stability Relationships of Carbamate Inhibitors of the FAAH Enzyme 127
Antinociceptive effects of the brain-impermeant fatty-acid amide hydrolase inhibitor URB937 125
Tandem mass spectrometric data–FAAH inhibitors activity relationships of some carbamic acid O-aryl esters 124
Synthesis and pharmacological characterization of URB447, a new cannabinoid receptor neutral antagonist 124
Derivato tetramerico ciclico dell’indol-3-carbinolo CTet come chemiopreventivo in tumori al seno estrogeno-dipendenti 123
FAAH and MGL Inhibitors. Design and Therapeutic Implications 123
Chronic stimulation of the endogenous anandamide tone reduces cocaine-seeking and cue-induced relapse in rats 122
Sintesi e studi di relazione struttura–attività/selettività su O-bifenil-3-ilcarbammati disostituiti quali inibitori periferici dell’enzima FAAH 121
Relationships Between Mass Spectrometry and Biological Stability of Some N-Acylethanolamine Acid Amidase Inhibitors 117
URB602, a Monoacylglycerol Lipase Inhibitor, Protects from the Long-term Consequences of a Neonatal Hypoxic-ischemic Brain Injury in Rats 116
Synthesis and Antiplatelet Activity of Gemfibrozil Chiral Analogues 116
Structure-Activity Relationships of Alkylcarbamic Acid Aryl Esters, as Fatty Acid Amide Hydrolase Inhibitors 115
Antinoceptive Effects of the N-Acylethanolamine Acid Amidase Inhibitor ARN077 in Rodent Pain Models 114
Methods, Compositions, and Other Compounds for Modulation of Monoacylglycerol Lipase Pain, and Stress-related Disorders 113
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 111
Synthesis and Biological Activity of Monoacylglycerol Lipase (MGL) Inhibitor URB602 and its Analogs 111
Design, Synthesis and SAR of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acids Amide Hydrolase Inhibitors 111
3D-QSAR study of carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 111
QSAR and molecular modelling investigations of a new series of alkyl carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 110
Antiplatelet Activity of Gemfibrozil Analogs 110
Anestetici locali (Cap. 14) 110
Osservatorio. Newly FDA-Approved Drugs (January-December 2002) 109
Correlation between energetics of collisionally activated decomposition, interaction energy and biological stability of some N-Acylethanolamine acid amidase inhibitors 109
A linear relationship between MS/MS data and FAAH inhibitory activity of some carbamates 108
Totale 16.469
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Categoria #
all - tutte 72.223
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 72.223
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.717 0 0 0 799 128 301 293 329 168 299 126 274
2020/20212.911 136 319 202 308 152 210 149 199 371 320 386 159
2021/20221.758 89 219 205 183 71 41 83 97 121 99 47 503
2022/20232.761 312 129 65 357 215 574 42 241 467 93 149 117
2023/2024781 96 54 56 91 54 166 37 49 15 66 28 69
2024/2025941 139 140 619 43 0 0 0 0 0 0 0 0
Totale 22.259