IRIS
DURANTI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 11.184
EU - Europa 8.027
AS - Asia 3.153
SA - Sud America 32
OC - Oceania 29
AF - Africa 9
Continente sconosciuto - Info sul continente non disponibili 9
Totale 22.443
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Nazione #
US - Stati Uniti d'America 11.122
GB - Regno Unito 2.534
CN - Cina 2.005
IT - Italia 1.707
UA - Ucraina 1.365
SE - Svezia 677
FI - Finlandia 508
TR - Turchia 473
SG - Singapore 390
DE - Germania 351
IE - Irlanda 327
RU - Federazione Russa 242
FR - Francia 133
IN - India 87
KR - Corea 57
CA - Canada 52
VN - Vietnam 49
PL - Polonia 45
JP - Giappone 38
NL - Olanda 27
AU - Australia 24
BE - Belgio 23
ES - Italia 22
BR - Brasile 15
IR - Iran 12
CH - Svizzera 9
CL - Cile 9
AT - Austria 8
HK - Hong Kong 8
HU - Ungheria 8
MX - Messico 8
RO - Romania 8
EU - Europa 7
HR - Croazia 7
NZ - Nuova Zelanda 5
PT - Portogallo 5
AE - Emirati Arabi Uniti 4
CO - Colombia 4
ID - Indonesia 4
SA - Arabia Saudita 4
BD - Bangladesh 3
GR - Grecia 3
LT - Lituania 3
NO - Norvegia 3
PE - Perù 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
EG - Egitto 2
IL - Israele 2
IQ - Iraq 2
LK - Sri Lanka 2
LU - Lussemburgo 2
LV - Lettonia 2
MA - Marocco 2
MD - Moldavia 2
MY - Malesia 2
NG - Nigeria 2
PK - Pakistan 2
TH - Thailandia 2
TW - Taiwan 2
BA - Bosnia-Erzegovina 1
BY - Bielorussia 1
DK - Danimarca 1
DZ - Algeria 1
EE - Estonia 1
FK - Isole Falkland (Malvinas) 1
JM - Giamaica 1
JO - Giordania 1
PA - Panama 1
PH - Filippine 1
SI - Slovenia 1
SL - Sierra Leone 1
SM - San Marino 1
UZ - Uzbekistan 1
ZA - Sudafrica 1
Totale 22.443
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Città #
Southend 2.316
Woodbridge 1.678
Ann Arbor 1.244
Houston 1.114
Jacksonville 1.090
Fairfield 1.052
Chandler 894
Nanjing 555
Ashburn 506
Cambridge 476
Wilmington 448
Seattle 427
Izmir 345
Singapore 310
Dublin 269
Boardman 253
Urbino 233
Helsinki 199
Nanchang 192
San Mateo 169
Beijing 167
Princeton 161
Hebei 118
Shenyang 118
New York 101
Changsha 98
Jiaxing 97
Istanbul 89
Tianjin 84
Velikiy Novgorod 82
Kunming 57
Seongnam 52
Menlo Park 48
San Diego 47
Dong Ket 46
Düsseldorf 46
Bremen 43
Milan 43
San Francisco 43
Moscow 41
Rome 41
Santa Clara 40
Toronto 35
Shanghai 34
Munich 33
London 32
Mülheim 32
Hangzhou 31
Jinan 31
Kraków 30
Guangzhou 28
Changchun 27
Ningbo 23
Lanzhou 22
Brussels 21
Ancona 19
Napoli 19
Palermo 19
Dearborn 18
Norwalk 18
Zhengzhou 18
Leawood 17
Taizhou 17
Des Moines 16
Haikou 16
Cava De' Tirreni 15
Mumbai 15
Parma 15
Hefei 14
Augusta 13
Bologna 13
Florence 13
Monte Porzio 13
Redwood City 13
Shenzhen 13
Naples 12
Wuppertal 11
Amsterdam 10
Auburn Hills 10
Padova 10
Bari 9
Colli Del Tronto 9
Lappeenranta 9
Madrid 9
Messina 9
Osimo 9
Tokyo 9
Fiorano Modenese 8
Hong Kong 8
Iesi 8
Melbourne 8
Pesaro 8
Portland 8
San Benedetto del Tronto 8
Venice 8
Verona 8
Vienna 8
Acton 7
Ardabil 7
Berlin 7
Totale 16.342
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Nome #
Inibitori dell’enzima NAAA (N-Acylethanolamine-Hydrolizing Acid Amidase) come nuovi agenti antinfiammatori 771
Unsaturated fatty acids lactose esters: cytotoxicity, permeability enhancement and antimicrobial activity 334
Pharmacokinetics, pharmacodynamics and safety studies on URB 937, a peripherally restricted fatty acid amide hydrolase inhibitor, in rats 315
Scoperta del primo inibitore dell’enzima idrolasi delle ammidi degli acidi grassi (FAAH) ad azione periferica 254
Derivatizzazione one-pot di indoli per la sintesi di triptofani, pirroloindoline, bis-indoli & co 253
Structure–Property Relationships of a Class of Carbamate-Based Fatty Acid Amide Hydrolase (FAAH) Inhibitors: Chemical and Biological Stability 224
2-Substituted-5-Methoxy-N-acyltryptamines: Synthesis, Binding Affinity for Melatonin Receptor, and Evaluation of the Biological Activity 217
Induction of Endoplasmic Reticulum Stress Response by the Indole-3-Carbinol Cyclic Tetrameric Derivative CTet in Human Breast Cancer Cell Lines 214
Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress 212
A New Synthesis of 2-Substituted DL-Tryptophan Derivatives 211
Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: Steric effects of N-alkyl chain on rat plasma and liver stability 211
A Second Generation of Carbamate-Based Fatty Acid Amide Hydrolase Inhibitors with Improved Activity in vivo 207
Sintesi e studi di relazione struttura-attività/stabilità di carbammati inibitori dell’enzima FAAH 206
Modulation of Anxiety Through Blockade of Anandamide Hydrolysis 205
Identification of a Bioactive Impurity in a Commercial Sample of 6-Methyl-2-p-tolylaminobenzo[d][1,3]oxazin-4-one (URB754) 202
Synthesis, Structure-Activity Relationships and In Vitro Toxicity Profile of Lactose-Based Fatty Acid Monoesters as Possible Drug Permeability Enhancers 198
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 197
Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats 194
Lactose oleate as new biocompatible surfactant for pharmaceutical applications 194
Synthesis and Biological Evaluation of a γ-Cyclodextrin-based Formulation of the Anticancer Agent 5,6,11,12,17,18,23,24-Octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 191
Antitumoral activity of indole-3-carbinol cyclic tri- and tetrameric derivatives mixture in human breast cancer cells: in vitro and in vivo studies 190
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation 187
Synthesis and Structure–Activity Relationships of a Series of Pyrrole Cannabinoid Receptor Agonists 186
The Synthetic Cannabinoid URB447 Reduces Brain Injury and the Associated White Matter Demyelination After Hypoxia-Ischemia in Neonatal Rats 186
2-Bromomelatonin: Synthesis and characterization of a potent melatonin agonist 185
Endocannabinoids in the Treatment of Mood Disorders: Evidence from Animal Models 182
The fatty acid amide hydrolase inhibitor URB597 modulates serotonin-dependent emotional behaviour, and serotonin1A and serotonin2A/C activity in the hippocampus 182
Peripherally Restricted FAAH Inhibitors 179
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis 178
Synthesis and Structure–Activity Relationship (SAR) of 2-Methyl-4-oxo-3-oxetanyl Carbamic Acid Esters, a Class of Potent N-Acylethanolamine Acid Amidase (NAAA) Inhibitors 177
Mechanisms of action and antiproliferative properties of URB631 in human breast cancer 176
Antimyotonic effects of enantiomers of mexiletine-like drugs 175
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 175
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 173
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 172
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 172
Therapeutic Effects of Tocainide and Mexiletine Analogs on Myotonic MTO and ADR Mice 171
Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brain 171
Synthesis and Evaluation of Saccharide-Based Aliphatic and Aromatic Esters as Antimicrobial and Antibiofilm Agents 171
Endocannabinoid Regulation of Acute and Protracted Nicotine Withdrawal: Effect of FAAH Inhibition 169
Application of 3D-QSAR in the Rational Design of Receptor Ligands and Enzyme Inhibitors 167
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 166
The Fatty Acid Amide Hydrolase Inhibitor URB597 (Cyclohexylcarbamic Acid 3’-Carbamoylbiphenyl-3-yl Ester) Reduces Neuropathic Pain after Oral Administration in Mice 166
URB602 Inhibits Monoacylglycerol Lipase and Selectively Blocks 2-Arachidonoylglycerol Degradation in Intact Brain Slices 165
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat 164
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus 162
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 162
O-Biphenyl-3-yl Carbamates as Peripheral FAAH Inhibitors: Synthesis and Structure–Activity (SAR) Relationship Studies 160
The fatty-acid amide hydrolase inhibitor URB597 does not affect triacylglycerol hydrolysis in rat tissues 160
Modulation of anxiety through blockade of anandamide hydrolysis 158
Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors 157
An endocannabinoid mechanism for stress-induced analgesia 156
Sintesi e studi biologici preliminari su analoghi di URB937, il primo inibitore ad azione periferica dell'enzima FAAH 156
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice 155
A practical and expeditious method for the preparation of the anticancer agent 5,6,11,12,17,18,23,24-octahydrocyclododeca[1,2-b:4,5-b’:7,8-b’’:10,11-b’’’]tetraindole (CTet) 155
Homologation of mexiletine alkyl chain and stereoselective blockade of skeletal muscle sodium channels 154
The indole-3-carbinol tetrameric derivative CTet inhibits cell proliferation via overexpression of p21/CDKN1A in both estrogen receptor-positive and triple-negative breast cancer cell lines 152
Indole-3-carbinol (I3C) Tetrameric Derivative (CTet) Inhibits Cell Cycle Progression Inducing Overexpression of p21/cip1/waf1 and GADD45A in Breast Cancer Cell Lines 152
Selective inhibition of 2 - AG hydrolysis enhances endocannabinoid signaling in the hippocampus 148
Pharmacological Profile of the Selective FAAH Inhibitor KDS-4103 (URB597) 146
SYNTHESIS AND EVALUATION OF SUGAR-BASED ALIPHATIC AND AROMATIC FATTY ACID ESTERS AS ANTIMICROBIAL AND ANTIBIOFILM AGENTS 146
N-alchil-O-arilcarbammati come inibitori delle idrolasi delle ammidi degli acidi grassi (FAAH): aspetti meccanicistici 143
Anandamide suppressess pain initiation through a peripheral endocannabinoid mechanism 142
N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis, Structure–Activity and Structure–Property Relationships 142
Synthesis and Structure–Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors 140
Contribution to the Study of 2-Aryloxy-1-phenyl and 2-Aryloxy-2-phenylethanols. Differentiation by Mass Spectrometry 140
Synthesis and Structure–Activity Relationship Studies of O-Biphenyl-3-yl Carbamates as Peripherally Restricted Fatty Acid Amide Hydrolase Inhibitors 140
Stereospecific synthesis of mexiletine and related compounds: Mitsunobu versus Williamson reaction 139
The CB1 Antagonist/CB2 Agonist URB447 Confers Neuroprotection after Neonatal Hypoxia-ischemia 138
2-Substituted-5-Methoxy-N-acyltryptamines: Synthesis and Binding Affinity to the Melatonin Receptor 134
Design, SAR and Biological Activity of a New Class of FAAH Inhibitors: Cyclohexyl Carbamic Acid Biphenyl-3-yl Esters 133
2 - Arachidonoylglycerol and anandamide are endocannabinoid mediators of stress - induced analgesia 133
α-Acylamino-β-lactones as a new class of N-acylethanolamine-hydrolyzing acid amidase (NAAA) inhibitors: synthesis and structure–activity relationships 132
Characterization of the Fatty Acid Amide Hydrolase Inhibitor Cyclohexyl Carbamic Acid 3'-Carbamoyl-biphenyl-3-yl Ester (URB597): Effects on Anandamide and Oleoylethanolamide Deactivation 131
A Versatile Biomimetic Approach to Diindolylmethane Derivatives as Potential Anticancer Agents 131
Identification of a Bioactive Impurity Present in a Sample of URB754 130
Synthesis and Structure-Activity/Stability Relationships of Carbamate Inhibitors of the FAAH Enzyme 129
Tandem mass spectrometric data–FAAH inhibitors activity relationships of some carbamic acid O-aryl esters 126
Synthesis and pharmacological characterization of URB447, a new cannabinoid receptor neutral antagonist 126
Antinociceptive effects of the brain-impermeant fatty-acid amide hydrolase inhibitor URB937 126
Derivato tetramerico ciclico dell’indol-3-carbinolo CTet come chemiopreventivo in tumori al seno estrogeno-dipendenti 125
Sintesi e studi di relazione struttura–attività/selettività su O-bifenil-3-ilcarbammati disostituiti quali inibitori periferici dell’enzima FAAH 125
FAAH and MGL Inhibitors. Design and Therapeutic Implications 124
Chronic stimulation of the endogenous anandamide tone reduces cocaine-seeking and cue-induced relapse in rats 123
Relationships Between Mass Spectrometry and Biological Stability of Some N-Acylethanolamine Acid Amidase Inhibitors 120
URB602, a Monoacylglycerol Lipase Inhibitor, Protects from the Long-term Consequences of a Neonatal Hypoxic-ischemic Brain Injury in Rats 117
Structure-Activity Relationships of Alkylcarbamic Acid Aryl Esters, as Fatty Acid Amide Hydrolase Inhibitors 117
Synthesis and Antiplatelet Activity of Gemfibrozil Chiral Analogues 117
Antinoceptive Effects of the N-Acylethanolamine Acid Amidase Inhibitor ARN077 in Rodent Pain Models 116
Methods, Compositions, and Other Compounds for Modulation of Monoacylglycerol Lipase Pain, and Stress-related Disorders 114
Anestetici locali (Cap. 14) 114
Composition and Methods of Inhibiting N-Acylethanolamine-hydrolyzing Acid Amidase 113
3D-QSAR study of carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 113
Antiplatelet Activity of Gemfibrozil Analogs 112
Synthesis and Biological Activity of Monoacylglycerol Lipase (MGL) Inhibitor URB602 and its Analogs 112
Design, Synthesis and SAR of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acids Amide Hydrolase Inhibitors 112
QSAR and molecular modelling investigations of a new series of alkyl carbamic acid aryl ester inhibitors of fatty acid amide hydrolase 111
Correlation between energetics of collisionally activated decomposition, interaction energy and biological stability of some N-Acylethanolamine acid amidase inhibitors 111
A linear relationship between MS/MS data and FAAH inhibitory activity of some carbamates 111
Osservatorio. Newly FDA-Approved Drugs (January-December 2002) 110
Totale 16.746
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Categoria #
all - tutte 76.666
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 76.666
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.790 0 0 0 0 0 301 293 329 168 299 126 274
2020/20212.911 136 319 202 308 152 210 149 199 371 320 386 159
2021/20221.758 89 219 205 183 71 41 83 97 121 99 47 503
2022/20232.761 312 129 65 357 215 574 42 241 467 93 149 117
2023/2024781 96 54 56 91 54 166 37 49 15 66 28 69
2024/20251.380 139 140 619 204 97 181 0 0 0 0 0 0
Totale 22.698