IRIS
BEDINI, ANNALIDA
 Distribuzione geografica
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Continente #
NA - Nord America 8.236
EU - Europa 5.944
AS - Asia 2.417
SA - Sud America 34
AF - Africa 25
Continente sconosciuto - Info sul continente non disponibili 22
OC - Oceania 10
AN - Antartide 1
Totale 16.689
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Nazione #
US - Stati Uniti d'America 8.176
GB - Regno Unito 2.074
CN - Cina 1.482
IT - Italia 1.024
UA - Ucraina 888
SE - Svezia 512
SG - Singapore 402
TR - Turchia 355
FI - Finlandia 339
RU - Federazione Russa 320
DE - Germania 297
IE - Irlanda 190
FR - Francia 78
IN - India 59
CA - Canada 52
NL - Olanda 48
BE - Belgio 44
KR - Corea 27
BR - Brasile 21
AT - Austria 20
HK - Hong Kong 19
EU - Europa 18
RO - Romania 18
ES - Italia 17
VN - Vietnam 17
JP - Giappone 14
KE - Kenya 11
PL - Polonia 11
CH - Svizzera 10
AL - Albania 9
AU - Australia 8
EG - Egitto 7
EE - Estonia 5
GR - Grecia 5
IL - Israele 5
PE - Perù 5
A2 - ???statistics.table.value.countryCode.A2??? 4
DK - Danimarca 4
ID - Indonesia 4
IR - Iran 4
PK - Pakistan 4
SI - Slovenia 4
TG - Togo 4
AM - Armenia 3
BD - Bangladesh 3
BG - Bulgaria 3
BZ - Belize 3
HU - Ungheria 3
IQ - Iraq 3
LT - Lituania 3
LU - Lussemburgo 3
MX - Messico 3
SA - Arabia Saudita 3
SK - Slovacchia (Repubblica Slovacca) 3
AE - Emirati Arabi Uniti 2
BO - Bolivia 2
CO - Colombia 2
CZ - Repubblica Ceca 2
GU - Guam 2
KZ - Kazakistan 2
PT - Portogallo 2
RS - Serbia 2
SM - San Marino 2
AR - Argentina 1
AZ - Azerbaigian 1
CL - Cile 1
FK - Isole Falkland (Malvinas) 1
GE - Georgia 1
GS - Georgia del Sud e Isole Sandwich Australi 1
HR - Croazia 1
IM - Isola di Man 1
IS - Islanda 1
JM - Giamaica 1
JO - Giordania 1
KG - Kirghizistan 1
KH - Cambogia 1
LA - Repubblica Popolare Democratica del Laos 1
MA - Marocco 1
MD - Moldavia 1
PA - Panama 1
PH - Filippine 1
PY - Paraguay 1
SC - Seychelles 1
TH - Thailandia 1
TW - Taiwan 1
ZA - Sudafrica 1
Totale 16.689
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Città #
Southend 1.893
Woodbridge 1.169
Fairfield 968
Houston 747
Jacksonville 710
Ann Arbor 677
Chandler 588
Ashburn 459
Cambridge 446
Seattle 378
Wilmington 376
Nanjing 351
Urbino 273
Izmir 257
Singapore 216
Dublin 188
Boardman 187
Nanchang 152
Helsinki 143
San Mateo 113
Beijing 110
Princeton 106
Shenyang 83
New York 82
Hebei 78
Changsha 74
Tianjin 72
Düsseldorf 70
Des Moines 66
Istanbul 62
Jiaxing 56
Brussels 43
Kunming 43
Moscow 40
Jinan 38
Velikiy Novgorod 38
Shanghai 37
Bremen 35
Toronto 31
Guangzhou 30
Venice 30
Hangzhou 27
San Diego 27
Amsterdam 26
London 26
San Francisco 26
Santa Clara 26
Nuremberg 24
Seongnam 24
Zhengzhou 23
Ningbo 22
Los Angeles 21
Mülheim 20
Rome 20
Haikou 19
Milan 18
Munich 18
Wuppertal 18
Tavullia 17
Changchun 15
Parma 15
Bologna 14
Lanzhou 14
Norwalk 13
Taizhou 12
Auburn Hills 11
Augusta 11
Hong Kong 11
Monte Porzio 11
North Bergen 11
Ancona 10
Casalecchio di Reno 10
Dong Ket 10
Frankfurt am Main 10
Leawood 10
Mcallen 10
Redwood City 10
Dearborn 9
Orange 9
Vienna 9
Scottsdale 8
Shenzhen 8
Tirana 8
West Jordan 8
Acquasanta Terme 7
Ascoli Piceno 7
Fuzhou 7
Madrid 7
Nairobi 7
Osimo 7
Portland 7
Prescot 7
Acton 6
Focsani 6
Timisoara 6
Athens 5
Borås 5
Fano 5
Jesi 5
Kiev 5
Totale 12.283
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Nome #
1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES AS LIGANDS AT THE GLYCINE-BINDING SITE OF THE N-METHYL-D-ASPARTATE RECEPTOR 343
1-Aminocyclopropane-1-carboxylic acid derivatives as ligands at the glicine-site of the NMDA receptor. 338
Iridium-Catalyzed Direct Synthesis of Tryptamine Derivatives from Indoles: Exploiting N-Protected β-Amino Alcohols as Alkylating Agents 328
1-Aminocyclopropane-1-carboxylic acid derivatives: Synthesis and NMDA receptor complex binding affinity study. 268
Synthesis of Tryptamine Derivatives via a Direct, One-Pot Reductive Alkylation of Indoles 258
Towards the development of 5-HT7 ligands combining serotonin-like and arylpiperazine moieties 248
An improved synthesis of cis-4-phenyl-2-propionamidotetralin (4-P-PDOT): a selective MT2 melatonin receptor antagonist. 246
1-Amminocyclopropane-1-Carboxylic Acid Derivatives: A New, General Synthesis and NMDA Receptor Complex Binding Affiniy Study 246
Therapeutic uses of melatonin and melatonin derivatives: a patent review (2012-2014) 245
Tricyclic Alkylamides as Melatonin Receptor Ligands with Antagonist or Inverse Agonist Activity 236
Synthesis and Configuration Determination of All Enantiopure Stereoisomers of the Melatonin Receptor Ligand 4-Phenyl-2-propionamidotetralin using an Expedient Optical Resolution of 4-Phenyl-2-tetralone 234
Antidepressant-like activity and cardioprotective effects of fatty acid amide hydrolase inhibitor URB694 in socially stressed Wistar Kyoto rats 234
Synthesis and Characterization of New Bivalent Agents as Melatonin- and Histamine H3-Ligands 228
Direct, One-Pot Reductive Alkylation of Anilines with Functionalized Acetals Mediated by Triethylsilane and TFA. Straightforward Route for Unsymmetrically Substituted Ethylenediamine 224
Tetrahydroquinoline Ring as a Versatile Bioisostere of Tetralin for Melatonin Receptor Ligands 220
(E)-3-(2-(N-phenylcarbamoyl)vinyl)pyrrole-2-carboxylic acid derivatives. A novel class of glycine site antagonists. 215
Design, synthesis and biological activity of hydrogen peroxide responsive arylboronate melatonin hybrids 214
Synthesis and Biological Activity of new melatonin dimeric derivatives. 211
4,5-Dihydroisoxazole and 4,5-dihydro-1,2,4-oxadiazole derivatives from cycloaddition reactions of nitrile oxides to alkyl N-(diphenylmethylene)-α ,β -dehydroamino acids 207
An improved route to cycloalka[b]pyrrole 2-carboxylates 204
3-(2-Carbamoylvinyl)-4,5-dimethylpyrrole-2-carboxylic acids as ligands at the NMDA glycine-binding site: a study on the 2-carbamoylvinyl chain modification 204
Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines 202
Synthetic Melatonin Receptor Ligands 192
Toward the Definition of Stereochemical Requirements for MT(2)-Selective Antagonists and Partial Agonists by Studying 4-Phenyl-2-propionamidotetralin Derivatives 192
The rationale for the development of melatonin receptor ligands 190
N-(Anilinoethyl)amides: design and synthesis of metabolically stable, selective melatonin receptor ligands. 188
Differentiation between isomeric 1-aminocyclopropane-1-carboxylic acid derivatives by means of chemical ionisation and mass selected collision induced dissociation 183
Plant-derived phenolic compounds prevent the DNA single-strand breakage and cytotoxicity induced by tert-butylhydroperoxide via an iron-chelating mechanism. 183
Pharmacokinetic and pharmacodynamic evaluation of ramelteon : an insomnia therapy 183
Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit 183
Cardioprotective effects of fatty acid amide hydrolase inhibitor URB694, in a rodent model of trait anxiety 182
Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand 181
Selective Melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways 176
Substituent effects on 1,3-dipolar cycloadditions to some 1,1-diphenyl-2-aza-1,3-butadiene derivatives 174
Diastereo- and enantioselective hydrogenation of a challenging enamide derived from 4-phenyl-2-tetralone: an appealing shortcut towards enantiopure cis-2-aminotetraline derivatives 174
MELATONIN RECEPTOR AGONISTS: SAR AND APPLICATIONS TO THE TREATMENT OF SLEEP-WAKE DISORDERS 173
Synthesis, Enantiomeric Resolution and Structure-Activity Relationship Study for a Series of 10,11-Dihydro-5H-dibenzo[a,d]cycloheptene MT2 Receptor Antagonists. 173
Melatonin MT1 and MT2 Receptors Exhibit Distinct Effects in the Modulation of Body Temperature across the Light/Dark Cycle 173
2,3-Dehydroamino acid derivatives as intermediates in the synthesis of heterocyclic compounds. 171
Application of 3D-QSAR in the Rational Design of Receptor Ligands and Enzyme Inhibitors 171
Design and synthesis of N-[3,3-diphenyl-propenyl]alkanamides as a novel class of potent MT2-selective Melatonin receptor ligands 168
N-(Substituted-anilinoethyl)acylamides: Design, Synthesis and Pharmacological Characterization of a New Class of Melatonin Receptor Ligands 165
2-[N-Acylamino(C1-C3)alkyl]indoles as MT1 melatonin receptor partial agonists, antagonists, and putative inverse agonists 165
Bivalent Ligand Approach on N-[2-[(3-methoxyphenyl)methylamino]ethyl]acetamide. Synthesis, Binding Affinity and Intrinsic Acivity for MT(1) and MT(2) melatonin Receptors. 164
Antiproliferative and pro-apoptotic activity of melatonin analogues on melanoma and breast cancer cells 163
Application of a non-electrophysiological method to study binding affinity and efficacy of glicine analogs to the glicine site of the NMDA receptor-ion channel complex. 161
N-Acyl-5- and -2,5-substituted tryptamines: synthesis, activity and affinity for human mt1 and MT2 melatonin receptors 160
Recent advances in the development of melatonin MT1 and MT2 receptor agonists 157
Anxiolytic effects of the melatonin MT2 receptor partial agonist UCM765: Comparison with melatonin and diazepam 156
N-acetiltriptamine 2,5-sostituite: sintesi e valutazione dell’attività biologica per i recettori melatoninergici MT1 e MT2 155
Alchilammidi tricicliche: legandi selettivi dei recettori melatoninergici MT1 e MT2 155
Synthesis and conformational study of 3,4-carbocyclic bridged indole melatonin and serotonin analogues 155
THREE-DIMENSIONAL QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP STUDIES ON SELECTED MT1 AND MT2 MELATONIN RECEPTOR LIGANDS: REQUIREMENTS FOR SUBTYPE SELECTIVITY AND INTRINSIC ACTIVITY MODULATION 153
Homology models of melatonin receptors: challenges and recent advances 153
Reactions of 3-Carbomethoxy-2-aza-1,3-Butadiene Derivatives with Dienophiles 152
(E)-3-[2-(Carbamoylvinyl)]pyrrol-2-carboxylic acid derivatives: A novel Class of glycine site Antagonists. 152
Strategies leading to MT2 selective melatonin receptor antagonists 151
Melatonin receptor agonists: new options for insomnia and depression treatment 150
Strategies leading to MT2 selective melatonin receptor antagonists 149
Analysis of structure-activity relationships for MT2 selective antagonists by melatonin MT1 and MT2 receptor models 149
Progettazione e Sintesi di nuovi ligandi dei recettori MT1 e MT2 della melatonina a struttura difenilalchilammidica. 145
Short synthesis of tryptophan and β -carboline derivatives by reaction of indoles with N-(diphenylmethylene)-α ,β -didehydroamino acid esters 142
Synthesis, antioxidant activity and structure-activity relationships for a new series of 2-(N-acylaminoethyl)indoles with melatonin-like cytoprotective activity 140
Synthesis and biological evaluation of 6-bromo-6-substituted penicillanic acid derivatives as beta-lactamase inhibitors. 135
ANTIMETASTATIC ACTION OF A NEW ANALOG OF DACARBAZINE IN MICE BEARING LEWIS LUNG CARCINOMA 134
SYNTHESIS, BINDING AFFINITY FOR THE MELATONIN RECEPTOR, AND EVALUATION OF THE BIOLOGICAL ACTIVITY OF NEW INDOLE-BASED MELATONIN ANALOGUES. 134
Melatonin, non-selective MT1/MT2 and selective MT2 receptor agonists: differential effects on the 24-hr vigilance states 134
Indole-based analogs of melatonin: in vitro antioxidant and cytoprotective activities 133
Synthesis, Pharmacological Characterization and QSAR Studies on 2-Substituted Indole Melatonin Receptor Ligands 132
MT2 selective melatonin receptor antagonists. Design and structure activity relationships 129
Towards the development of mixed MT1-agonist/MT2-antagonist melatonin receptor ligands 128
Antioxidant and cytoprotective activity of indole derivatives related to melatonin, 127
A novel melatonin partial agonist with sleep-promoting properties 126
N-(anilinoethyl)acylamides: new melatonin receptor ligands with sleep inducing properties. 125
Synthesis of new 6-bromopenicillanic acid derivatives as potential β-lactamase inhibitors. 121
MT2 selective melatonin receptor antagonists: design and structure-activity relationships 121
Correlation of the antimetastatic properties of aryltriazenes with their Electron Impact Ionization Mass Spectronomy 118
2-Arylmelatonin analogues: Probing the 2-phenyl binding pocket of melatonin MT1 and MT2 receptors 115
MT1-Selective Melatonin Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Dynamics Investigation of N-{[(3-O-Substituted)anilino]alkyl}amides 114
A novel melatonin partial agonist with sleep promoting properties and anti-anxiety effects. 113
Synthesis of new C-6 alkylidene penicillin derivatives as beta-lactamase inhibitors 113
INVESTIGATION OF SOME 2,3-DIDEHYDRO AMINOACIFS BY FAST ATOM BOMBARDMENT, CHEMICAL IONIZATION AND MASS-SELECTED COLLISION-INDUCED DISSOCIATION MASS SPECTROMETRY. 109
Analoghi della melatonina: effetto dei sostituenti sull’attività di derivati N-acetiltriptaminici. 107
A novel melatonin partial agonist with sleep-promoting properties. 107
Synthesis, binding and QSAR studies of new 2-substituted melatonergic agonists. 107
Selective increase of Slow Wave Sleep (SWS) by a novel melatonin partial agonist 106
Rapid and transient stimulation of intracellular reactive oxygen species by melatonin in normal tumor leukocytes, Toxicology and apllied Pharmacology, 239(1), 37-45 (2009) 105
In vitro metabolism of the melatonin MT2-receptor selective ligand UCM765 by rat, mouse and human liver substrates 105
2-5-Disubstituted tryptamines a selective serotonin 5HT6 receptor agonists. 102
Synthesis of new 6-alkyliden penicillin derivatives as potential beta-lactamase inhibitors. 101
Antioxidant and cytoprotective effect of indole derivatives related to melatonin 99
Selective increase of Slow Wave Sleep (SWS) by melatonin 2 receptors. 98
Novel melatonin ligands having antidepressant activity as well as sleep inducine properties 94
STRUCTURAL CHARACTERIZATION OF ISOMERIC DIDEHYDRO AMINOACIDS USING CHEMIAL IONIZATION 94
Relazioni struttura attività per analoghi indolici della melatonina ad azione antiossidante e citoprotettiva 90
Design and structure-activity relationships of subtype selective melatonin receptor ligands. 89
In vitro evaluation of antioxidant activity for a series of 2-acylaminoethylindoles, PBA2004 87
N-(Anilinoethyl)amide Melatonergic Ligands with Improved Water Solubility and Metabolic Stability 83
Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria 82
Design and synthesis of metabolically protected melatonin receptor agonists 81
Totale 16.253
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Categoria #
all - tutte 60.970
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 60.970
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020422 0 0 0 0 0 0 0 0 0 211 87 124
2020/20211.989 61 137 81 267 108 135 119 156 326 225 255 119
2021/20221.284 128 145 125 165 23 35 57 62 86 72 31 355
2022/20231.850 209 122 56 207 163 405 7 165 296 56 122 42
2023/2024565 32 58 28 77 40 100 32 13 67 57 18 43
2024/20251.569 136 105 428 110 67 162 277 109 167 8 0 0
Totale 16.945