IRIS
CANTONI, ORAZIO
 Distribuzione geografica
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Continente #
NA - Nord America 23.455
EU - Europa 13.841
AS - Asia 7.336
SA - Sud America 605
AF - Africa 101
OC - Oceania 33
Continente sconosciuto - Info sul continente non disponibili 32
Totale 45.403
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Nazione #
US - Stati Uniti d'America 23.227
GB - Regno Unito 4.311
CN - Cina 3.561
SG - Singapore 2.180
NL - Olanda 1.943
UA - Ucraina 1.734
IT - Italia 1.167
SE - Svezia 1.072
DE - Germania 1.047
FI - Finlandia 890
RU - Federazione Russa 743
TR - Turchia 707
BR - Brasile 478
FR - Francia 314
IE - Irlanda 311
VN - Vietnam 240
KR - Corea 145
CA - Canada 140
IN - India 102
PL - Polonia 91
BD - Bangladesh 88
HK - Hong Kong 78
MX - Messico 69
JP - Giappone 54
AR - Argentina 49
BE - Belgio 43
ES - Italia 35
AU - Australia 31
EU - Europa 28
IQ - Iraq 27
MA - Marocco 27
ZA - Sudafrica 24
PK - Pakistan 21
CL - Cile 18
LT - Lituania 18
CO - Colombia 16
EC - Ecuador 16
ID - Indonesia 16
RO - Romania 15
AE - Emirati Arabi Uniti 13
KE - Kenya 13
IR - Iran 12
IL - Israele 11
VE - Venezuela 11
GR - Grecia 10
KG - Kirghizistan 9
SM - San Marino 9
BG - Bulgaria 8
PT - Portogallo 8
TG - Togo 8
UZ - Uzbekistan 8
AT - Austria 7
CH - Svizzera 7
MD - Moldavia 7
PH - Filippine 7
PY - Paraguay 7
SA - Arabia Saudita 7
TN - Tunisia 7
AL - Albania 6
CZ - Repubblica Ceca 6
DZ - Algeria 6
TH - Thailandia 6
DK - Danimarca 5
EG - Egitto 5
HU - Ungheria 5
JO - Giordania 5
MY - Malesia 5
PA - Panama 5
A2 - ???statistics.table.value.countryCode.A2??? 4
CR - Costa Rica 4
JM - Giamaica 4
KW - Kuwait 4
LB - Libano 4
LV - Lettonia 4
NO - Norvegia 4
PE - Perù 4
SK - Slovacchia (Repubblica Slovacca) 4
UY - Uruguay 4
AO - Angola 3
LU - Lussemburgo 3
NP - Nepal 3
SN - Senegal 3
SY - Repubblica araba siriana 3
TW - Taiwan 3
AZ - Azerbaigian 2
BA - Bosnia-Erzegovina 2
BO - Bolivia 2
EE - Estonia 2
GE - Georgia 2
HN - Honduras 2
HR - Croazia 2
KY - Cayman, isole 2
LK - Sri Lanka 2
NZ - Nuova Zelanda 2
OM - Oman 2
RS - Serbia 2
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
BN - Brunei Darussalam 1
BW - Botswana 1
Totale 45.385
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Città #
Southend 3.804
Woodbridge 2.811
Fairfield 2.615
Houston 2.077
Ashburn 1.969
Amsterdam 1.917
Ann Arbor 1.632
Dallas 1.398
Jacksonville 1.398
Singapore 1.084
Seattle 1.052
Cambridge 1.045
Wilmington 984
Chandler 948
San Jose 910
Nanjing 727
Izmir 573
Helsinki 463
Beijing 445
Boardman 389
Munich 367
Dublin 311
Urbino 304
Nanchang 274
New York 242
Princeton 208
Lauterbourg 204
San Mateo 192
Los Angeles 167
Council Bluffs 160
Shenyang 147
Düsseldorf 139
Bremen 138
Tianjin 135
Seongnam 132
Changsha 113
Hebei 112
Moscow 105
San Diego 105
Jiaxing 93
Mülheim 92
Santa Clara 81
Kunming 79
Chicago 73
Hong Kong 73
London 72
Ho Chi Minh City 71
Istanbul 71
São Paulo 67
Jinan 65
Shanghai 65
San Francisco 64
Buffalo 60
Toronto 59
Hanoi 56
Guangzhou 54
Hangzhou 49
Orem 49
Brussels 43
Columbus 43
Velikiy Novgorod 41
Venice 40
Montreal 39
Tokyo 39
Kraków 38
Lanzhou 38
Warsaw 37
Changchun 36
Des Moines 35
Frankfurt am Main 34
Ningbo 33
Mexico City 31
The Dalles 31
Brooklyn 28
Taizhou 27
Chennai 26
Zhengzhou 26
Denver 25
Falls Church 25
Milan 25
Atlanta 24
Salt Lake City 24
Stockholm 24
Turku 24
Shenzhen 23
Rio de Janeiro 22
Haikou 21
Kilburn 21
Norwalk 21
Tampa 19
Casablanca 18
Wuppertal 18
Nuremberg 17
Rome 17
Auburn Hills 16
Dong Ket 16
Johannesburg 16
Manchester 16
Phoenix 16
Ankara 15
Totale 34.217
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Nome #
1,3 dideazaadenosine is a mitogen for cultured mammalian cells. 3.227
Intracellular dehydroascorbic acid inhibits SVCT2-dependent transport of ascorbic acid in mitochondria 431
Superoxide dictates the mode of U937 cell ascorbic acid uptake and prevents the enhancing effects of the vitamin to otherwise non-toxic levels of reactive oxygen/nitrogen species 421
Mitochondrial ascorbic acid prevents mitochondrial O2.- formation, an event critical for U937 cell apoptosis induced by arsenite through both autophagic-dependent and independent mechanisms 385
U937 cell apoptosis induced by arsenite is prevented by low concentrations of mitochondrial ascorbic acid with hardly any effect mediated by the cytosolic fraction of the vitamin 325
A moderate decline in U937 cell GSH levels triggers PI3 kinase/Akt-dependent Bad phosphorylation, thereby preventing an otherwise prompt apoptotic response 302
A novel mechanism, uniquely dependent on mitochondrial calcium accumulation, whereby peroxynitrite promotes formation of superoxide/hydrogen peroxide and the ensuing strand scission of genomic DNA 296
Arsenite-induced mitochondrial superoxide formation: time and concentration requirements for the effects of the metalloid on the endoplasmic reticulum and mitochondria 295
Sodium-dependent transport of ascorbic acid in U937 cell mitochondria. 294
A novel biological role of dehydroascorbic acid: Inhibition of Na+-dependent transport of ascorbic acid. 294
The role of arachidonic acid in the regulation of nitric oxide synthase isoforms by HIV gp120 protein in astroglial cells 289
The mitochondrial transporter of ascorbic acid functions with high affinity in the presence of low millimolar concentrations of sodium and in the absence of calcium and magnesium 288
Apoptosis of human lymphocytes in the absence or presence of internucleosomal DNA cleavage 286
Apoptosis and necrosis following exposure of U937 cells to increasing concentrations of hydrogen peroxide: the effect of the poly(ADP-ribose)polymerase inhibitor 3-aminobenzamide. 284
Mitochondrial ascorbic acid is responsible for enhanced susceptibility of U937 cells to the toxic effects of peroxynitrite 284
Arachidonic acid induces calcium-dependent mitochondrial formation of species promoting strand scission of genomic DNA 281
5-Hydroxyeicosatetraenoic acid is a key intermediate of the arachidonate-dependent protective signaling in monocytes/macrophages exposed to peroxynitrite. 280
Arsenite induces DNA damage via mitochondrial ROS and induction of mitochondrial permeability transition 277
Calcium signals between the ryanodine receptor- and mitochondria critically regulate the effects of arsenite on mitochondrial superoxide formation and on the ensuing survival vs apoptotic signaling 275
Mitochondria accumulate large amounts of quercetin: prevention of mitochondrial damage and release upon oxidation of the extramitochondrial fraction of the flavonoid 272
Analogues of benzamide as poly(ADP-ribose)transferase inhibitors: a study on structure activity relationships. 268
Dexamethasone Promotes Toxicity in U937 Cells Exposed to Otherwise Non-toxic Concentrations of Peroxynitrite: Pivotal Role for Lipocortin 1 Mediated Inhibition of Cytosolic Phospholipase A2 265
Isolation and preliminary characterization of a Chinese hamster ovary cell line with high-degree resistance to hydrogen peroxide. 261
Direct excision of 50 Kb pair DNA fragments from megabase-sized fragments produced during apoptotic cleavage of genomic DNA. 261
Meprobamate/morphine interactions on avoidance and escape behaviour in rats. 258
Cytotoxic impact of DNA single vs double strand breaks in oxidatively injured cells 258
The study of the mechanism of arsenite toxicity in respiration-deficient cells reveals that NADPH oxidase-derived superoxide promotes the same downstream events mediated by mitochondrial superoxide in respiration-proficient cells 256
Cyclic GMP-dependent inhibition of acid sphingomyelinase by nitric oxide: an early step in protection against apoptosis. 253
Assessing bad sub-cellular localization under conditions associated with prevention or promotion of mitochondrial permeability transition-dependent toxicity. 253
A novel nonsense mutation in the APTX gene associated with delayed DNA single-strand break removal fails to enhance sensitivity to different genotoxic agents. 252
Cross-resistance to heavy metals in hydrogen peroxide-resistant CHO cell variants. 250
Arachidonic acid: a key molecule for astrocyte survival to peroxynitrite. 250
Differentiation-associated loss of ryanodine receptors: a strategy adopted by monocytes/macrophages to prevent the DNA single-strand breakage induced by peroxynitrite. 249
Simultaneous determination of DNA double strand breaks and DNA fragment size in cultured mammalian cells exposed to hydrogen peroxide/histidine or etoposide with CHEF electrophoresis. 247
Low levels of hydrogen peroxide and L-histidine induce DNA double-strand breakage and apoptosis. 246
The L-histidine-mediated enhancement of hydrogen peroxide-induced DNA double strand breakage and cytotoxicity does not involve metabolic processes. 246
Action of cystine in the cytotoxic response of Escherichia coli cells exposed to hydrogen peroxide. 246
U937 cell necrosis mediated by peroxynitrite is not caused by depletion of ATP and is prevented by arachidonate via an ATP-dependent mechanism. 246
Analysis of metal-induced DNA lesions and DNA-repair replication in mammalian cells. 246
The arachidonate-dependent survival signaling preventing toxicity in monocytes/macrophages exposed to peroxynitrite. 244
Characterization of two novel SETX mutations in AOA2 patients reveals aspects of the pathophysiological role of senataxin. 244
Intramitochondrial Ascorbic Acid Enhances the Formation of Mitochondrial Superoxide Induced by Peroxynitrite via a Ca(2+)-Independent Mechanism 244
The arachidonate-dependent cytoprotective signaling evoked by peroxynitrite is a general response of the monocyte/macrophage lineage 244
Adriamycin does not affect the repair of X-ray induced DNA single strand breaks. 243
Differentiation of Promonocytic U937 Cells to Monocytes Is Associated with Reduced Mitochondrial Transport of Ascorbic Acid 242
The dual role of mitochondrial superoxide in arsenite toxicity: Signaling at the boundary between apoptotic commitment and cytoprotection 242
The induction/loss of the oxidant-resistant phenotype of Chinese hamster ovary (CHO) cell variants does not correlate with sensitivity to DNA single strand breakage by hydrogen peroxide. 241
[Aryloxy- and arylthioalkylamine hypolipidemic agents] 241
Studies with low micromolar levels of ascorbic and dehydroascorbic acid fail to unravel a preferential route for vitamin C uptake and accumulation in U937 cells 241
Crosstalk between ERO1α and ryanodine receptor in arsenite-dependent mitochondrial ROS formation 241
Inhibition of complex III promotes loss of Ca2+ dependence for mitochondrial superoxide formation and permeability transition evoked by peroxynitrite. 240
3-Aminobenzamide inhibition of protein kinase C at a cellular level. 240
A method for disposing of lysates from cells analyzed for DNA damage by filter elution assay. 238
ERK1/2 regulates two sequential steps promoting monocyte survival to peroxynitrite. 238
Analysis of the induction of alkali sensitive sites in the DNA by chromate and other agents that induce single strand breaks. 238
Modulation of the oxidative response of cultured mammalian cells by L-histidine. 236
The effect of hydrogen peroxide/L-histidine-induced DNA single- vs. double-strand breaks on poly(ADP-ribose)polymerase. 236
Evidence for separate mechanisms of cytotoxicity in mammalian cells treated with hydrogen peroxide in the absence or presence of L-histidine 234
Novel SETX variants in a patient with ataxia, neuropathy, and oculomotor apraxia are associated with normal sensitivity to oxidative DNA damaging agents 232
AG8 cells, which are highly resistant to hydrogen peroxide, display collateral sensitivity to the combination of hydrogen peroxide and L-histidine. 231
L-glutamine prevents the L-histidine-mediated enhancement of hydrogen peroxide-induced cytotoxicity. 230
Prevention of necrosis and activation of apoptosis in oxidatively injured human myeloid leukemia U937 cells. 230
Arachidonic acid inhibits neuronal nitric oxide synthase elicited by proinflammatory stimuli and promotes astrocyte survival with both exogenous and endogenous peroxynitrite via different mechanisms. 229
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. 228
The antioxidant butylated hydroxytoluene induces apoptosis in human U937 cells: the role of hydrogen peroxide and altered redox state. 228
Survival pathways triggered by peroxynitrite in cells belonging to the monocyte/macrophage lineage 228
Osmotically driven radial diffusion of single-stranded DNA fragments on an agarose bed as a convenient measure of DNA strand scission. 226
A downstream role for protein kinase C alpha in the cytosolic phospholipase A2-dependent protective signalling mediated by peroxynitrite in U937 cells. 222
L-histidine-mediated enhancement of hydrogen peroxide-induced cytotoxicity: relationships between DNA single/double strand breakage and cell killing. 222
Structural requirements for inhibitors of poly(ADP-ribose) polymerase. 221
SVCT2-DEPENDENT PLASMA AND MITOCHONDRIAL MEMBRANE TRANSPORT OF ASCORBIC ACID IN DIFFERENTIATING MYOBLASTS 220
Quercetin prevents DNA single strand breakage and cytotoxicity caused by tert-butylhydroperoxide: free radical scavenging versus iron chelating mechanism. 219
Peroxynitrite damages U937 cell DNA via the intermediate formation of mitochondrial oxidants. 217
Effect of 3-aminobenzamide on DNA strand-break rejoining and cytotoxicity in CHO cells treated with hydrogen peroxide. 216
Susceptibility of rat astrocytes to DNA strand scission induced by activation of NADPH oxidase and collateral resistance to the effects of peroxynitrite. 216
Calcium chelator Quin 2 prevents hydrogen-peroxide-induced DNA breakage and cytotoxicity. 216
Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals 215
Cell signalling and cytotoxicity by peroxynitrite. 214
Peroxynitrite stimulates the activity of cytosolic phospholipase A2 in U937 cells: the extent of arachidonic acid formation regulates the balance between cell survival or death. 212
Products of the phospholipase A2 pathway mediate the dihydrorhodamine fluorescence response evoked by endogenous and exogenous peroxynitrite in PC12 cells. 212
Substituted Benzamides as Poly(ADP-Ribose) transferase Inhibitors: Development of new Derivatives by using Computer Graphics Techniques 210
ERK1/2-dependent regulation of U937 cell survival after exposure to peroxynitrite. 210
DOWNREGULATION OF NITRIC OXIDE FORMATION BY CYTOSOLIC PHOSPHOLIPASE A2-RELEASED ARACHIDONIC ACID. 210
Peroxynitrite-induced mitochondrial translocation of PKCalpha causes U937 cell survival. 210
Modulation of muscarinic receptor-stimulated phosphoinositide breakdown by sulfhydryl group modification is a general response in different rat brain regions and depends on the stage of brain development. 207
Plant-derived phenolic compounds prevent the DNA single-strand breakage and cytotoxicity induced by tert-butylhydroperoxide via an iron-chelating mechanism. 207
Cell-density-dependent regulation of ATP levels during the growth cycle of cultured Chinese Hamster Ovary cells 207
Randomly distributed DNA single strand breaks are not lethal for mammalian cells. 205
Pivotal Role of Arachidonic Acid in the Regulation of Neuronal Nitric Oxide Synthase Activity and Inducible Nitric Oxide Synthase Expression in Activated Astrocytes 203
Delayed formation of hydrogen peroxide mediates the lethal response evoked by peroxynitrite in U937 cells 203
DNA breakage caused by hydrogen peroxide produced during the metabolism of 2-methyl-1,4-naphthoquinone (menadione) does not contribute to the cytotoxic action of the quinone. 203
Differential effect of the amino acid cystine in cultured mammalian and bacterial cells exposed to oxidative stress. 202
Use of mammalian DNA repair-deficient mutants to assess the effects of toxic metal compounds on DNA. 202
Role of Bcl-2 in the arachidonate-mediated survival signaling preventing mitochondrial permeability transition-dependent U937 cell necrosis induced by peroxynitrite 202
Hydrogen peroxide cytotoxicity under conditions of normal or reduced catalase activity in H2O2-sensitive and -resistant Chinese hamster ovary (CHO) cell variants. 202
Hydrogen peroxide-and fetal bovine serum-induced DNA synthesis in vascular smooth muscle cells: positive and negative regulation by protein kinase C isoforms. 202
TNFa enhances the DNA single-strand breakage induced by the short-chain lipid hydroperoxide analogue tert-butylhydroperoxide via ceramide-dependent inhibition of complex III followed by enforced superoxide and hydrogen peroxide formation 201
Hydrogen peroxide generated at the level of mitochondria in response to peroxynitrite promotes U937 cell death via inhibition of the cytoprotective signalling mediated by cytosolic phospholipase A2 201
Clozapine blunts mitochondrial biogenesis in differentiating adipocytes: The increased ATP demand is met via stimulation of electron transport chain expression and activity in residual mitochondria 198
Electron transport-mediated wasteful consumption of NADH promotes the lethal response of U937 cells to tert-butylhydroperoxide. 198
Totale 27.431
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Categoria #
all - tutte 160.357
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 160.357
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021214 0 0 0 0 0 0 0 0 0 0 0 214
2021/20222.605 281 288 248 359 79 87 137 165 154 201 49 557
2022/20233.237 337 142 32 404 353 715 9 227 560 101 240 117
2023/2024882 113 71 69 116 86 215 34 46 2 56 5 69
2024/20253.669 123 267 571 161 103 333 497 325 513 207 283 286
2025/202610.614 588 1.089 1.486 1.268 621 528 1.086 265 2.452 671 408 152
Totale 45.807