IRIS
CANTONI, ORAZIO
 Distribuzione geografica
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Continente #
NA - Nord America 25.320
EU - Europa 14.009
AS - Asia 7.454
SA - Sud America 673
Continente sconosciuto - Info sul continente non disponibili 437
AF - Africa 106
OC - Oceania 33
Totale 48.032
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Nazione #
US - Stati Uniti d'America 24.972
GB - Regno Unito 4.359
CN - Cina 3.596
SG - Singapore 2.214
NL - Olanda 1.944
UA - Ucraina 1.738
IT - Italia 1.252
SE - Svezia 1.072
DE - Germania 1.049
FI - Finlandia 890
RU - Federazione Russa 746
TR - Turchia 708
BR - Brasile 511
FR - Francia 318
IE - Irlanda 311
VN - Vietnam 245
CA - Canada 188
KR - Corea 146
IN - India 103
BD - Bangladesh 93
PL - Polonia 92
HK - Hong Kong 90
MX - Messico 79
JP - Giappone 56
AR - Argentina 51
BE - Belgio 44
ES - Italia 35
AU - Australia 31
CO - Colombia 29
MA - Marocco 29
EU - Europa 28
IQ - Iraq 27
EC - Ecuador 25
ID - Indonesia 24
ZA - Sudafrica 24
PK - Pakistan 22
LT - Lituania 21
CL - Cile 19
VE - Venezuela 18
RO - Romania 15
CR - Costa Rica 14
JM - Giamaica 14
AE - Emirati Arabi Uniti 13
KE - Kenya 13
HN - Honduras 12
IL - Israele 12
IR - Iran 12
GR - Grecia 10
PH - Filippine 10
PT - Portogallo 10
AL - Albania 9
BG - Bulgaria 9
KG - Kirghizistan 9
SM - San Marino 9
CH - Svizzera 8
DK - Danimarca 8
EE - Estonia 8
MY - Malesia 8
SA - Arabia Saudita 8
TG - Togo 8
TH - Thailandia 8
TT - Trinidad e Tobago 8
UZ - Uzbekistan 8
AT - Austria 7
MD - Moldavia 7
NI - Nicaragua 7
PY - Paraguay 7
TN - Tunisia 7
CZ - Repubblica Ceca 6
DZ - Algeria 6
GT - Guatemala 6
EG - Egitto 5
HU - Ungheria 5
JO - Giordania 5
PA - Panama 5
PE - Perù 5
UY - Uruguay 5
A2 - ???statistics.table.value.countryCode.A2??? 4
KW - Kuwait 4
LB - Libano 4
LV - Lettonia 4
NO - Norvegia 4
NP - Nepal 4
PR - Porto Rico 4
SK - Slovacchia (Repubblica Slovacca) 4
TW - Taiwan 4
AO - Angola 3
BO - Bolivia 3
GE - Georgia 3
LU - Lussemburgo 3
SC - Seychelles 3
SN - Senegal 3
SY - Repubblica araba siriana 3
AZ - Azerbaigian 2
BA - Bosnia-Erzegovina 2
BB - Barbados 2
HR - Croazia 2
KY - Cayman, isole 2
LK - Sri Lanka 2
NZ - Nuova Zelanda 2
Totale 47.596
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Città #
Southend 3.804
Woodbridge 2.811
Fairfield 2.616
Ashburn 2.421
Houston 2.083
Amsterdam 1.917
Ann Arbor 1.632
Dallas 1.426
Jacksonville 1.401
Singapore 1.098
San Jose 1.057
Seattle 1.057
Cambridge 1.047
Wilmington 985
Chandler 948
Nanjing 727
Izmir 574
Beijing 464
Helsinki 463
Boardman 391
Munich 367
Council Bluffs 334
Dublin 311
Urbino 308
Nanchang 274
New York 259
Princeton 208
Lauterbourg 204
Los Angeles 197
San Mateo 192
Santa Clara 163
Shenyang 147
Düsseldorf 139
Bremen 138
Tianjin 135
Seongnam 132
Changsha 113
Hebei 112
San Diego 107
Moscow 105
Chicago 96
Jiaxing 93
Mülheim 92
Hong Kong 84
Kunming 79
São Paulo 78
Ho Chi Minh City 74
London 73
San Francisco 73
Toronto 72
Istanbul 71
Shanghai 70
Buffalo 66
Jinan 65
Hanoi 58
Guangzhou 54
Orem 52
Hangzhou 49
Columbus 46
Montreal 46
Brussels 44
Phoenix 42
The Dalles 42
Tokyo 41
Velikiy Novgorod 41
Venice 41
Kraków 38
Lanzhou 38
Warsaw 38
Changchun 36
Des Moines 36
Brooklyn 35
Atlanta 34
Denver 34
Frankfurt am Main 34
Mexico City 34
Milan 34
Ningbo 33
North Bergen 33
Salt Lake City 28
Taizhou 27
Chennai 26
Zhengzhou 26
Falls Church 25
Rome 25
Stockholm 24
Turku 24
Shenzhen 23
Norwalk 22
Rio de Janeiro 22
Haikou 21
Kilburn 21
Casablanca 20
Tampa 20
Charlotte 18
Wuppertal 18
Brasília 17
Nuremberg 17
Auburn Hills 16
Boston 16
Totale 35.422
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Nome #
1,3 dideazaadenosine is a mitogen for cultured mammalian cells. 3.250
Intracellular dehydroascorbic acid inhibits SVCT2-dependent transport of ascorbic acid in mitochondria 442
Superoxide dictates the mode of U937 cell ascorbic acid uptake and prevents the enhancing effects of the vitamin to otherwise non-toxic levels of reactive oxygen/nitrogen species 428
Mitochondrial ascorbic acid prevents mitochondrial O2.- formation, an event critical for U937 cell apoptosis induced by arsenite through both autophagic-dependent and independent mechanisms 396
U937 cell apoptosis induced by arsenite is prevented by low concentrations of mitochondrial ascorbic acid with hardly any effect mediated by the cytosolic fraction of the vitamin 344
A moderate decline in U937 cell GSH levels triggers PI3 kinase/Akt-dependent Bad phosphorylation, thereby preventing an otherwise prompt apoptotic response 313
A novel biological role of dehydroascorbic acid: Inhibition of Na+-dependent transport of ascorbic acid. 311
Mitochondrial Uptake and Accumulation of Vitamin C: What Can We Learn From Cell Cultures Studies? 309
Arsenite-induced mitochondrial superoxide formation: time and concentration requirements for the effects of the metalloid on the endoplasmic reticulum and mitochondria 309
A novel mechanism, uniquely dependent on mitochondrial calcium accumulation, whereby peroxynitrite promotes formation of superoxide/hydrogen peroxide and the ensuing strand scission of genomic DNA 302
Sodium-dependent transport of ascorbic acid in U937 cell mitochondria. 300
The mitochondrial transporter of ascorbic acid functions with high affinity in the presence of low millimolar concentrations of sodium and in the absence of calcium and magnesium 299
Apoptosis of human lymphocytes in the absence or presence of internucleosomal DNA cleavage 298
Apoptosis and necrosis following exposure of U937 cells to increasing concentrations of hydrogen peroxide: the effect of the poly(ADP-ribose)polymerase inhibitor 3-aminobenzamide. 297
Arsenite induces DNA damage via mitochondrial ROS and induction of mitochondrial permeability transition 294
Arachidonic acid induces calcium-dependent mitochondrial formation of species promoting strand scission of genomic DNA 293
The role of arachidonic acid in the regulation of nitric oxide synthase isoforms by HIV gp120 protein in astroglial cells 293
Mitochondrial ascorbic acid is responsible for enhanced susceptibility of U937 cells to the toxic effects of peroxynitrite 291
5-Hydroxyeicosatetraenoic acid is a key intermediate of the arachidonate-dependent protective signaling in monocytes/macrophages exposed to peroxynitrite. 287
Calcium signals between the ryanodine receptor- and mitochondria critically regulate the effects of arsenite on mitochondrial superoxide formation and on the ensuing survival vs apoptotic signaling 283
Dexamethasone Promotes Toxicity in U937 Cells Exposed to Otherwise Non-toxic Concentrations of Peroxynitrite: Pivotal Role for Lipocortin 1 Mediated Inhibition of Cytosolic Phospholipase A2 280
Mitochondria accumulate large amounts of quercetin: prevention of mitochondrial damage and release upon oxidation of the extramitochondrial fraction of the flavonoid 280
Analogues of benzamide as poly(ADP-ribose)transferase inhibitors: a study on structure activity relationships. 277
The study of the mechanism of arsenite toxicity in respiration-deficient cells reveals that NADPH oxidase-derived superoxide promotes the same downstream events mediated by mitochondrial superoxide in respiration-proficient cells 274
Meprobamate/morphine interactions on avoidance and escape behaviour in rats. 272
Isolation and preliminary characterization of a Chinese hamster ovary cell line with high-degree resistance to hydrogen peroxide. 271
Direct excision of 50 Kb pair DNA fragments from megabase-sized fragments produced during apoptotic cleavage of genomic DNA. 269
Cytotoxic impact of DNA single vs double strand breaks in oxidatively injured cells 268
Crosstalk between ERO1α and ryanodine receptor in arsenite-dependent mitochondrial ROS formation 268
A novel nonsense mutation in the APTX gene associated with delayed DNA single-strand break removal fails to enhance sensitivity to different genotoxic agents. 262
Cross-resistance to heavy metals in hydrogen peroxide-resistant CHO cell variants. 261
Characterization of two novel SETX mutations in AOA2 patients reveals aspects of the pathophysiological role of senataxin. 261
Analysis of metal-induced DNA lesions and DNA-repair replication in mammalian cells. 260
Intramitochondrial Ascorbic Acid Enhances the Formation of Mitochondrial Superoxide Induced by Peroxynitrite via a Ca(2+)-Independent Mechanism 260
Arachidonic acid: a key molecule for astrocyte survival to peroxynitrite. 258
Assessing bad sub-cellular localization under conditions associated with prevention or promotion of mitochondrial permeability transition-dependent toxicity. 258
The arachidonate-dependent survival signaling preventing toxicity in monocytes/macrophages exposed to peroxynitrite. 257
Cyclic GMP-dependent inhibition of acid sphingomyelinase by nitric oxide: an early step in protection against apoptosis. 257
The L-histidine-mediated enhancement of hydrogen peroxide-induced DNA double strand breakage and cytotoxicity does not involve metabolic processes. 257
U937 cell necrosis mediated by peroxynitrite is not caused by depletion of ATP and is prevented by arachidonate via an ATP-dependent mechanism. 255
The dual role of mitochondrial superoxide in arsenite toxicity: Signaling at the boundary between apoptotic commitment and cytoprotection 255
Low levels of hydrogen peroxide and L-histidine induce DNA double-strand breakage and apoptosis. 254
Simultaneous determination of DNA double strand breaks and DNA fragment size in cultured mammalian cells exposed to hydrogen peroxide/histidine or etoposide with CHEF electrophoresis. 254
Differentiation-associated loss of ryanodine receptors: a strategy adopted by monocytes/macrophages to prevent the DNA single-strand breakage induced by peroxynitrite. 254
The arachidonate-dependent cytoprotective signaling evoked by peroxynitrite is a general response of the monocyte/macrophage lineage 254
Action of cystine in the cytotoxic response of Escherichia coli cells exposed to hydrogen peroxide. 253
The induction/loss of the oxidant-resistant phenotype of Chinese hamster ovary (CHO) cell variants does not correlate with sensitivity to DNA single strand breakage by hydrogen peroxide. 252
Inhibition of complex III promotes loss of Ca2+ dependence for mitochondrial superoxide formation and permeability transition evoked by peroxynitrite. 251
Differentiation of Promonocytic U937 Cells to Monocytes Is Associated with Reduced Mitochondrial Transport of Ascorbic Acid 250
Adriamycin does not affect the repair of X-ray induced DNA single strand breaks. 250
A method for disposing of lysates from cells analyzed for DNA damage by filter elution assay. 249
[Aryloxy- and arylthioalkylamine hypolipidemic agents] 248
Studies with low micromolar levels of ascorbic and dehydroascorbic acid fail to unravel a preferential route for vitamin C uptake and accumulation in U937 cells 248
3-Aminobenzamide inhibition of protein kinase C at a cellular level. 247
Analysis of the induction of alkali sensitive sites in the DNA by chromate and other agents that induce single strand breaks. 246
ERK1/2 regulates two sequential steps promoting monocyte survival to peroxynitrite. 244
Modulation of the oxidative response of cultured mammalian cells by L-histidine. 244
AG8 cells, which are highly resistant to hydrogen peroxide, display collateral sensitivity to the combination of hydrogen peroxide and L-histidine. 244
The effect of hydrogen peroxide/L-histidine-induced DNA single- vs. double-strand breaks on poly(ADP-ribose)polymerase. 244
Evidence for separate mechanisms of cytotoxicity in mammalian cells treated with hydrogen peroxide in the absence or presence of L-histidine 241
The antioxidant butylated hydroxytoluene induces apoptosis in human U937 cells: the role of hydrogen peroxide and altered redox state. 240
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. 238
Arachidonic acid inhibits neuronal nitric oxide synthase elicited by proinflammatory stimuli and promotes astrocyte survival with both exogenous and endogenous peroxynitrite via different mechanisms. 238
Novel SETX variants in a patient with ataxia, neuropathy, and oculomotor apraxia are associated with normal sensitivity to oxidative DNA damaging agents 238
Prevention of necrosis and activation of apoptosis in oxidatively injured human myeloid leukemia U937 cells. 238
L-glutamine prevents the L-histidine-mediated enhancement of hydrogen peroxide-induced cytotoxicity. 236
Quercetin prevents DNA single strand breakage and cytotoxicity caused by tert-butylhydroperoxide: free radical scavenging versus iron chelating mechanism. 235
Survival pathways triggered by peroxynitrite in cells belonging to the monocyte/macrophage lineage 235
Cell signalling and cytotoxicity by peroxynitrite. 234
Osmotically driven radial diffusion of single-stranded DNA fragments on an agarose bed as a convenient measure of DNA strand scission. 234
A downstream role for protein kinase C alpha in the cytosolic phospholipase A2-dependent protective signalling mediated by peroxynitrite in U937 cells. 231
Structural requirements for inhibitors of poly(ADP-ribose) polymerase. 230
Peroxynitrite damages U937 cell DNA via the intermediate formation of mitochondrial oxidants. 227
L-histidine-mediated enhancement of hydrogen peroxide-induced cytotoxicity: relationships between DNA single/double strand breakage and cell killing. 227
Effect of 3-aminobenzamide on DNA strand-break rejoining and cytotoxicity in CHO cells treated with hydrogen peroxide. 226
Calcium chelator Quin 2 prevents hydrogen-peroxide-induced DNA breakage and cytotoxicity. 226
Susceptibility of rat astrocytes to DNA strand scission induced by activation of NADPH oxidase and collateral resistance to the effects of peroxynitrite. 224
Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals 223
SVCT2-DEPENDENT PLASMA AND MITOCHONDRIAL MEMBRANE TRANSPORT OF ASCORBIC ACID IN DIFFERENTIATING MYOBLASTS 223
Clozapine blunts mitochondrial biogenesis in differentiating adipocytes: The increased ATP demand is met via stimulation of electron transport chain expression and activity in residual mitochondria 222
Cell-density-dependent regulation of ATP levels during the growth cycle of cultured Chinese Hamster Ovary cells 220
ERK1/2-dependent regulation of U937 cell survival after exposure to peroxynitrite. 219
Plant-derived phenolic compounds prevent the DNA single-strand breakage and cytotoxicity induced by tert-butylhydroperoxide via an iron-chelating mechanism. 218
Intracellular ascorbic acid enhances the DNA single-strand breakage and toxicity induced by peroxynitrite in U937 cells 217
tert-Butylhydroperoxide induces peroxynitrite-dependent mitochondrial permeability transition leading PC12 cells to necrosis 216
Products of the phospholipase A2 pathway mediate the dihydrorhodamine fluorescence response evoked by endogenous and exogenous peroxynitrite in PC12 cells. 216
Substituted Benzamides as Poly(ADP-Ribose) transferase Inhibitors: Development of new Derivatives by using Computer Graphics Techniques 215
DOWNREGULATION OF NITRIC OXIDE FORMATION BY CYTOSOLIC PHOSPHOLIPASE A2-RELEASED ARACHIDONIC ACID. 215
Peroxynitrite-induced mitochondrial translocation of PKCalpha causes U937 cell survival. 215
Use of mammalian DNA repair-deficient mutants to assess the effects of toxic metal compounds on DNA. 214
Modulation of muscarinic receptor-stimulated phosphoinositide breakdown by sulfhydryl group modification is a general response in different rat brain regions and depends on the stage of brain development. 214
Peroxynitrite stimulates the activity of cytosolic phospholipase A2 in U937 cells: the extent of arachidonic acid formation regulates the balance between cell survival or death. 214
Hydrogen peroxide cytotoxicity under conditions of normal or reduced catalase activity in H2O2-sensitive and -resistant Chinese hamster ovary (CHO) cell variants. 214
Role of Bcl-2 in the arachidonate-mediated survival signaling preventing mitochondrial permeability transition-dependent U937 cell necrosis induced by peroxynitrite 212
Delayed formation of hydrogen peroxide mediates the lethal response evoked by peroxynitrite in U937 cells 210
Hydrogen peroxide-and fetal bovine serum-induced DNA synthesis in vascular smooth muscle cells: positive and negative regulation by protein kinase C isoforms. 210
Hydrogen peroxide generated at the level of mitochondria in response to peroxynitrite promotes U937 cell death via inhibition of the cytoprotective signalling mediated by cytosolic phospholipase A2 209
Randomly distributed DNA single strand breaks are not lethal for mammalian cells. 208
TNFa enhances the DNA single-strand breakage induced by the short-chain lipid hydroperoxide analogue tert-butylhydroperoxide via ceramide-dependent inhibition of complex III followed by enforced superoxide and hydrogen peroxide formation 207
Differential effect of the amino acid cystine in cultured mammalian and bacterial cells exposed to oxidative stress. 207
Totale 28.521
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Categoria #
all - tutte 171.982
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 171.982
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.788 0 0 0 359 79 87 137 165 154 201 49 557
2022/20233.237 337 142 32 404 353 715 9 227 560 101 240 117
2023/2024882 113 71 69 116 86 215 34 46 2 56 5 69
2024/20253.669 123 267 571 161 103 333 497 325 513 207 283 286
2025/202610.649 588 1.089 1.486 1.268 621 528 1.086 265 2.452 671 408 187
2026/20272.190 311 189 944 746 0 0 0 0 0 0 0 0
Totale 48.032