IRIS
CANTONI, ORAZIO
 Distribuzione geografica
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Continente #
NA - Nord America 21.731
EU - Europa 11.361
AS - Asia 6.307
SA - Sud America 542
AF - Africa 79
Continente sconosciuto - Info sul continente non disponibili 32
OC - Oceania 31
Totale 40.083
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Nazione #
US - Stati Uniti d'America 21.546
GB - Regno Unito 4.297
CN - Cina 3.370
UA - Ucraina 1.732
SG - Singapore 1.606
IT - Italia 1.104
SE - Svezia 1.071
DE - Germania 1.028
FI - Finlandia 823
TR - Turchia 702
RU - Federazione Russa 525
BR - Brasile 442
IE - Irlanda 311
VN - Vietnam 175
KR - Corea 141
CA - Canada 117
FR - Francia 114
PL - Polonia 85
IN - India 74
NL - Olanda 66
MX - Messico 59
JP - Giappone 50
BE - Belgio 43
AR - Argentina 37
ES - Italia 32
AU - Australia 29
BD - Bangladesh 29
EU - Europa 28
HK - Hong Kong 24
MA - Marocco 24
ZA - Sudafrica 19
LT - Lituania 18
CL - Cile 16
CO - Colombia 15
ID - Indonesia 15
EC - Ecuador 14
RO - Romania 14
IQ - Iraq 13
PK - Pakistan 13
AE - Emirati Arabi Uniti 12
IL - Israele 11
IR - Iran 11
GR - Grecia 9
KG - Kirghizistan 9
SM - San Marino 9
TG - Togo 8
AT - Austria 7
BG - Bulgaria 7
CH - Svizzera 7
KE - Kenya 7
MD - Moldavia 7
PT - Portogallo 7
CZ - Repubblica Ceca 6
PY - Paraguay 6
SA - Arabia Saudita 6
VE - Venezuela 6
DK - Danimarca 5
DZ - Algeria 5
JO - Giordania 5
MY - Malesia 5
A2 - ???statistics.table.value.countryCode.A2??? 4
AL - Albania 4
EG - Egitto 4
HU - Ungheria 4
LB - Libano 4
PH - Filippine 4
TN - Tunisia 4
UZ - Uzbekistan 4
JM - Giamaica 3
KW - Kuwait 3
LU - Lussemburgo 3
LV - Lettonia 3
NO - Norvegia 3
PE - Perù 3
SK - Slovacchia (Repubblica Slovacca) 3
SN - Senegal 3
TH - Thailandia 3
AO - Angola 2
BA - Bosnia-Erzegovina 2
BO - Bolivia 2
EE - Estonia 2
GE - Georgia 2
HR - Croazia 2
LK - Sri Lanka 2
NZ - Nuova Zelanda 2
RS - Serbia 2
SY - Repubblica araba siriana 2
TW - Taiwan 2
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
AZ - Azerbaigian 1
BN - Brunei Darussalam 1
BY - Bielorussia 1
CG - Congo 1
CR - Costa Rica 1
ET - Etiopia 1
HN - Honduras 1
IM - Isola di Man 1
IS - Islanda 1
KH - Cambogia 1
Totale 40.069
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Città #
Southend 3.804
Woodbridge 2.811
Fairfield 2.615
Houston 2.075
Ashburn 1.747
Ann Arbor 1.632
Jacksonville 1.396
Dallas 1.391
Seattle 1.049
Cambridge 1.045
Wilmington 984
Chandler 948
Nanjing 727
Singapore 663
Izmir 573
Beijing 402
Helsinki 399
Boardman 369
Munich 367
Dublin 311
Urbino 301
Nanchang 273
New York 221
Princeton 208
San Mateo 192
Los Angeles 156
Shenyang 147
Düsseldorf 139
Bremen 137
Tianjin 134
Seongnam 132
Changsha 112
Hebei 112
San Diego 105
Moscow 103
Jiaxing 93
Mülheim 92
Kunming 79
Chicago 69
Istanbul 69
London 68
Jinan 65
Santa Clara 65
São Paulo 65
Buffalo 60
Shanghai 60
San Francisco 56
Ho Chi Minh City 55
Guangzhou 53
Toronto 53
Hangzhou 46
Amsterdam 43
Brussels 43
Velikiy Novgorod 41
Venice 40
Kraków 38
Hanoi 37
Lanzhou 37
Changchun 36
Tokyo 36
Des Moines 33
Montreal 33
Ningbo 33
Warsaw 33
Brooklyn 27
Mexico City 27
Taizhou 27
Frankfurt am Main 26
Orem 26
Zhengzhou 26
Falls Church 24
Turku 24
Stockholm 23
Shenzhen 22
Denver 21
Haikou 21
Hong Kong 21
Kilburn 21
Milan 21
Norwalk 21
Rio de Janeiro 21
Tampa 19
Atlanta 18
Casablanca 18
Wuppertal 18
Auburn Hills 16
Chennai 16
Dong Ket 16
Ankara 15
Pesaro 15
Salt Lake City 15
Manchester 14
Orange 14
Tappahannock 14
Johannesburg 13
Melbourne 13
Nuremberg 13
Paris 13
Phoenix 13
Boston 12
Totale 29.995
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Nome #
1,3 dideazaadenosine is a mitogen for cultured mammalian cells. 1.340
Intracellular dehydroascorbic acid inhibits SVCT2-dependent transport of ascorbic acid in mitochondria 412
Superoxide dictates the mode of U937 cell ascorbic acid uptake and prevents the enhancing effects of the vitamin to otherwise non-toxic levels of reactive oxygen/nitrogen species 409
Mitochondrial ascorbic acid prevents mitochondrial O2.- formation, an event critical for U937 cell apoptosis induced by arsenite through both autophagic-dependent and independent mechanisms 367
U937 cell apoptosis induced by arsenite is prevented by low concentrations of mitochondrial ascorbic acid with hardly any effect mediated by the cytosolic fraction of the vitamin 299
The role of arachidonic acid in the regulation of nitric oxide synthase isoforms by HIV gp120 protein in astroglial cells 284
Sodium-dependent transport of ascorbic acid in U937 cell mitochondria. 275
Apoptosis and necrosis following exposure of U937 cells to increasing concentrations of hydrogen peroxide: the effect of the poly(ADP-ribose)polymerase inhibitor 3-aminobenzamide. 274
A novel biological role of dehydroascorbic acid: Inhibition of Na+-dependent transport of ascorbic acid. 272
Apoptosis of human lymphocytes in the absence or presence of internucleosomal DNA cleavage 269
A novel mechanism, uniquely dependent on mitochondrial calcium accumulation, whereby peroxynitrite promotes formation of superoxide/hydrogen peroxide and the ensuing strand scission of genomic DNA 267
A moderate decline in U937 cell GSH levels triggers PI3 kinase/Akt-dependent Bad phosphorylation, thereby preventing an otherwise prompt apoptotic response 266
5-Hydroxyeicosatetraenoic acid is a key intermediate of the arachidonate-dependent protective signaling in monocytes/macrophages exposed to peroxynitrite. 265
The mitochondrial transporter of ascorbic acid functions with high affinity in the presence of low millimolar concentrations of sodium and in the absence of calcium and magnesium 260
Dexamethasone Promotes Toxicity in U937 Cells Exposed to Otherwise Non-toxic Concentrations of Peroxynitrite: Pivotal Role for Lipocortin 1 Mediated Inhibition of Cytosolic Phospholipase A2 259
Arsenite induces DNA damage via mitochondrial ROS and induction of mitochondrial permeability transition 259
Arachidonic acid induces calcium-dependent mitochondrial formation of species promoting strand scission of genomic DNA 258
Analogues of benzamide as poly(ADP-ribose)transferase inhibitors: a study on structure activity relationships. 256
Mitochondrial ascorbic acid is responsible for enhanced susceptibility of U937 cells to the toxic effects of peroxynitrite 252
Mitochondria accumulate large amounts of quercetin: prevention of mitochondrial damage and release upon oxidation of the extramitochondrial fraction of the flavonoid 249
Direct excision of 50 Kb pair DNA fragments from megabase-sized fragments produced during apoptotic cleavage of genomic DNA. 246
Assessing bad sub-cellular localization under conditions associated with prevention or promotion of mitochondrial permeability transition-dependent toxicity. 246
Cross-resistance to heavy metals in hydrogen peroxide-resistant CHO cell variants. 244
The study of the mechanism of arsenite toxicity in respiration-deficient cells reveals that NADPH oxidase-derived superoxide promotes the same downstream events mediated by mitochondrial superoxide in respiration-proficient cells 244
Meprobamate/morphine interactions on avoidance and escape behaviour in rats. 242
Calcium signals between the ryanodine receptor- and mitochondria critically regulate the effects of arsenite on mitochondrial superoxide formation and on the ensuing survival vs apoptotic signaling 241
Cytotoxic impact of DNA single vs double strand breaks in oxidatively injured cells 240
Action of cystine in the cytotoxic response of Escherichia coli cells exposed to hydrogen peroxide. 236
Differentiation-associated loss of ryanodine receptors: a strategy adopted by monocytes/macrophages to prevent the DNA single-strand breakage induced by peroxynitrite. 235
Low levels of hydrogen peroxide and L-histidine induce DNA double-strand breakage and apoptosis. 234
Isolation and preliminary characterization of a Chinese hamster ovary cell line with high-degree resistance to hydrogen peroxide. 234
The arachidonate-dependent cytoprotective signaling evoked by peroxynitrite is a general response of the monocyte/macrophage lineage 234
A novel nonsense mutation in the APTX gene associated with delayed DNA single-strand break removal fails to enhance sensitivity to different genotoxic agents. 233
Intramitochondrial Ascorbic Acid Enhances the Formation of Mitochondrial Superoxide Induced by Peroxynitrite via a Ca(2+)-Independent Mechanism 233
The induction/loss of the oxidant-resistant phenotype of Chinese hamster ovary (CHO) cell variants does not correlate with sensitivity to DNA single strand breakage by hydrogen peroxide. 232
Simultaneous determination of DNA double strand breaks and DNA fragment size in cultured mammalian cells exposed to hydrogen peroxide/histidine or etoposide with CHEF electrophoresis. 232
U937 cell necrosis mediated by peroxynitrite is not caused by depletion of ATP and is prevented by arachidonate via an ATP-dependent mechanism. 231
Adriamycin does not affect the repair of X-ray induced DNA single strand breaks. 231
Studies with low micromolar levels of ascorbic and dehydroascorbic acid fail to unravel a preferential route for vitamin C uptake and accumulation in U937 cells 229
Analysis of metal-induced DNA lesions and DNA-repair replication in mammalian cells. 229
The arachidonate-dependent survival signaling preventing toxicity in monocytes/macrophages exposed to peroxynitrite. 228
Cyclic GMP-dependent inhibition of acid sphingomyelinase by nitric oxide: an early step in protection against apoptosis. 228
ERK1/2 regulates two sequential steps promoting monocyte survival to peroxynitrite. 227
The effect of hydrogen peroxide/L-histidine-induced DNA single- vs. double-strand breaks on poly(ADP-ribose)polymerase. 227
Differentiation of Promonocytic U937 Cells to Monocytes Is Associated with Reduced Mitochondrial Transport of Ascorbic Acid 227
3-Aminobenzamide inhibition of protein kinase C at a cellular level. 227
Characterization of two novel SETX mutations in AOA2 patients reveals aspects of the pathophysiological role of senataxin. 225
[Aryloxy- and arylthioalkylamine hypolipidemic agents] 224
Modulation of the oxidative response of cultured mammalian cells by L-histidine. 224
A method for disposing of lysates from cells analyzed for DNA damage by filter elution assay. 223
Arachidonic acid: a key molecule for astrocyte survival to peroxynitrite. 223
Inhibition of complex III promotes loss of Ca2+ dependence for mitochondrial superoxide formation and permeability transition evoked by peroxynitrite. 223
Analysis of the induction of alkali sensitive sites in the DNA by chromate and other agents that induce single strand breaks. 221
The antioxidant butylated hydroxytoluene induces apoptosis in human U937 cells: the role of hydrogen peroxide and altered redox state. 219
Novel SETX variants in a patient with ataxia, neuropathy, and oculomotor apraxia are associated with normal sensitivity to oxidative DNA damaging agents 218
Prevention of necrosis and activation of apoptosis in oxidatively injured human myeloid leukemia U937 cells. 218
The L-histidine-mediated enhancement of hydrogen peroxide-induced DNA double strand breakage and cytotoxicity does not involve metabolic processes. 217
Evidence for separate mechanisms of cytotoxicity in mammalian cells treated with hydrogen peroxide in the absence or presence of L-histidine 217
L-glutamine prevents the L-histidine-mediated enhancement of hydrogen peroxide-induced cytotoxicity. 217
Arsenite-induced mitochondrial superoxide formation: time and concentration requirements for the effects of the metalloid on the endoplasmic reticulum and mitochondria 216
Survival pathways triggered by peroxynitrite in cells belonging to the monocyte/macrophage lineage 216
AG8 cells, which are highly resistant to hydrogen peroxide, display collateral sensitivity to the combination of hydrogen peroxide and L-histidine. 214
The dual role of mitochondrial superoxide in arsenite toxicity: Signaling at the boundary between apoptotic commitment and cytoprotection 214
Osmotically driven radial diffusion of single-stranded DNA fragments on an agarose bed as a convenient measure of DNA strand scission. 214
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. 212
L-histidine-mediated enhancement of hydrogen peroxide-induced cytotoxicity: relationships between DNA single/double strand breakage and cell killing. 212
Arachidonic acid inhibits neuronal nitric oxide synthase elicited by proinflammatory stimuli and promotes astrocyte survival with both exogenous and endogenous peroxynitrite via different mechanisms. 211
Structural requirements for inhibitors of poly(ADP-ribose) polymerase. 210
Effect of 3-aminobenzamide on DNA strand-break rejoining and cytotoxicity in CHO cells treated with hydrogen peroxide. 209
Peroxynitrite damages U937 cell DNA via the intermediate formation of mitochondrial oxidants. 209
Calcium chelator Quin 2 prevents hydrogen-peroxide-induced DNA breakage and cytotoxicity. 209
A downstream role for protein kinase C alpha in the cytosolic phospholipase A2-dependent protective signalling mediated by peroxynitrite in U937 cells. 206
Products of the phospholipase A2 pathway mediate the dihydrorhodamine fluorescence response evoked by endogenous and exogenous peroxynitrite in PC12 cells. 205
ERK1/2-dependent regulation of U937 cell survival after exposure to peroxynitrite. 204
Peroxynitrite-induced mitochondrial translocation of PKCalpha causes U937 cell survival. 203
Substituted Benzamides as Poly(ADP-Ribose) transferase Inhibitors: Development of new Derivatives by using Computer Graphics Techniques 202
Plant-derived phenolic compounds prevent the DNA single-strand breakage and cytotoxicity induced by tert-butylhydroperoxide via an iron-chelating mechanism. 202
Hydrogen peroxide-and fetal bovine serum-induced DNA synthesis in vascular smooth muscle cells: positive and negative regulation by protein kinase C isoforms. 199
Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals 199
Randomly distributed DNA single strand breaks are not lethal for mammalian cells. 197
Cell signalling and cytotoxicity by peroxynitrite. 197
DOWNREGULATION OF NITRIC OXIDE FORMATION BY CYTOSOLIC PHOSPHOLIPASE A2-RELEASED ARACHIDONIC ACID. 197
Susceptibility of rat astrocytes to DNA strand scission induced by activation of NADPH oxidase and collateral resistance to the effects of peroxynitrite. 196
Quercetin prevents DNA single strand breakage and cytotoxicity caused by tert-butylhydroperoxide: free radical scavenging versus iron chelating mechanism. 195
Use of mammalian DNA repair-deficient mutants to assess the effects of toxic metal compounds on DNA. 194
Modulation of muscarinic receptor-stimulated phosphoinositide breakdown by sulfhydryl group modification is a general response in different rat brain regions and depends on the stage of brain development. 194
Peroxynitrite stimulates the activity of cytosolic phospholipase A2 in U937 cells: the extent of arachidonic acid formation regulates the balance between cell survival or death. 194
Role of Bcl-2 in the arachidonate-mediated survival signaling preventing mitochondrial permeability transition-dependent U937 cell necrosis induced by peroxynitrite 194
tert-Butylhydroperoxide induces peroxynitrite-dependent mitochondrial permeability transition leading PC12 cells to necrosis 194
DNA breakage caused by hydrogen peroxide produced during the metabolism of 2-methyl-1,4-naphthoquinone (menadione) does not contribute to the cytotoxic action of the quinone. 194
Differential effect of the amino acid cystine in cultured mammalian and bacterial cells exposed to oxidative stress. 193
Cell-density-dependent regulation of ATP levels during the growth cycle of cultured Chinese Hamster Ovary cells 193
Hydrogen peroxide cytotoxicity under conditions of normal or reduced catalase activity in H2O2-sensitive and -resistant Chinese hamster ovary (CHO) cell variants. 193
Soluble and insoluble nickel compounds induce DNA repair synthesis in cultured mammalian cells. 191
Pivotal Role of Arachidonic Acid in the Regulation of Neuronal Nitric Oxide Synthase Activity and Inducible Nitric Oxide Synthase Expression in Activated Astrocytes 190
SVCT2-DEPENDENT PLASMA AND MITOCHONDRIAL MEMBRANE TRANSPORT OF ASCORBIC ACID IN DIFFERENTIATING MYOBLASTS 190
Hydrogen peroxide generated at the level of mitochondria in response to peroxynitrite promotes U937 cell death via inhibition of the cytoprotective signalling mediated by cytosolic phospholipase A2 189
Delayed formation of hydrogen peroxide mediates the lethal response evoked by peroxynitrite in U937 cells 188
Endogenous and exogenous nitric oxide enhance the DNA strand scission induced by tert-butylhydroperoxide in PC12 cells via peroxynitrite-dependent and independent mechanisms, respectively. 188
Peroxynitrite mobilizes calcium ions from ryanodine-sensitive stores, a process associated with the mitochondrial accumulation of the cation and the enforced formation of species mediating cleavage of genomic DNA. 188
Totale 23.966
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Categoria #
all - tutte 147.023
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 147.023
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20212.671 0 0 0 0 0 333 367 334 547 361 515 214
2021/20222.605 281 288 248 359 79 87 137 165 154 201 49 557
2022/20233.237 337 142 32 404 353 715 9 227 560 101 240 117
2023/2024882 113 71 69 116 86 215 34 46 2 56 5 69
2024/20253.669 123 267 571 161 103 333 497 325 513 207 283 286
2025/20265.293 588 1.089 1.486 1.268 621 241 0 0 0 0 0 0
Totale 40.486