IRIS
CANTONI, ORAZIO
 Distribuzione geografica
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Continente #
NA - Nord America 22.921
EU - Europa 13.804
AS - Asia 7.158
SA - Sud America 604
AF - Africa 101
Continente sconosciuto - Info sul continente non disponibili 32
OC - Oceania 32
Totale 44.652
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Nazione #
US - Stati Uniti d'America 22.712
GB - Regno Unito 4.309
CN - Cina 3.500
SG - Singapore 2.118
NL - Olanda 1.940
UA - Ucraina 1.734
IT - Italia 1.136
SE - Svezia 1.072
DE - Germania 1.047
FI - Finlandia 890
RU - Federazione Russa 743
TR - Turchia 707
BR - Brasile 478
FR - Francia 314
IE - Irlanda 311
VN - Vietnam 240
KR - Corea 144
CA - Canada 124
IN - India 102
PL - Polonia 91
HK - Hong Kong 70
MX - Messico 69
JP - Giappone 54
AR - Argentina 48
BD - Bangladesh 43
BE - Belgio 43
ES - Italia 35
AU - Australia 30
EU - Europa 28
IQ - Iraq 27
MA - Marocco 27
ZA - Sudafrica 24
PK - Pakistan 21
CL - Cile 18
LT - Lituania 18
CO - Colombia 16
EC - Ecuador 16
ID - Indonesia 16
RO - Romania 14
KE - Kenya 13
AE - Emirati Arabi Uniti 12
IR - Iran 12
IL - Israele 11
VE - Venezuela 11
GR - Grecia 10
KG - Kirghizistan 9
SM - San Marino 9
BG - Bulgaria 8
PT - Portogallo 8
TG - Togo 8
UZ - Uzbekistan 8
AT - Austria 7
CH - Svizzera 7
MD - Moldavia 7
PH - Filippine 7
PY - Paraguay 7
SA - Arabia Saudita 7
TN - Tunisia 7
AL - Albania 6
CZ - Repubblica Ceca 6
DZ - Algeria 6
TH - Thailandia 6
DK - Danimarca 5
EG - Egitto 5
HU - Ungheria 5
JO - Giordania 5
MY - Malesia 5
PA - Panama 5
A2 - ???statistics.table.value.countryCode.A2??? 4
KW - Kuwait 4
LB - Libano 4
LV - Lettonia 4
NO - Norvegia 4
PE - Perù 4
SK - Slovacchia (Repubblica Slovacca) 4
UY - Uruguay 4
AO - Angola 3
CR - Costa Rica 3
JM - Giamaica 3
LU - Lussemburgo 3
NP - Nepal 3
SN - Senegal 3
SY - Repubblica araba siriana 3
TW - Taiwan 3
AZ - Azerbaigian 2
BA - Bosnia-Erzegovina 2
BO - Bolivia 2
EE - Estonia 2
GE - Georgia 2
HN - Honduras 2
HR - Croazia 2
LK - Sri Lanka 2
NZ - Nuova Zelanda 2
OM - Oman 2
RS - Serbia 2
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
BN - Brunei Darussalam 1
BW - Botswana 1
BY - Bielorussia 1
Totale 44.634
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Città #
Southend 3.804
Woodbridge 2.811
Fairfield 2.615
Houston 2.075
Ashburn 1.949
Amsterdam 1.915
Ann Arbor 1.632
Jacksonville 1.396
Dallas 1.394
Singapore 1.077
Seattle 1.049
Cambridge 1.045
Wilmington 984
Chandler 948
San Jose 790
Nanjing 727
Izmir 573
Helsinki 463
Beijing 433
Boardman 369
Munich 367
Dublin 311
Urbino 304
Nanchang 273
New York 226
Princeton 208
Lauterbourg 204
San Mateo 192
Los Angeles 158
Shenyang 147
Düsseldorf 139
Bremen 137
Tianjin 134
Seongnam 132
Changsha 112
Hebei 112
Moscow 105
San Diego 105
Jiaxing 93
Mülheim 92
Kunming 79
Santa Clara 75
Ho Chi Minh City 71
Istanbul 71
London 71
Chicago 70
São Paulo 67
Hong Kong 65
Jinan 65
Shanghai 64
Buffalo 60
San Francisco 57
Hanoi 56
Toronto 55
Guangzhou 54
Hangzhou 47
Orem 45
Brussels 43
Velikiy Novgorod 41
Venice 40
Tokyo 39
Kraków 38
Lanzhou 37
Warsaw 37
Changchun 36
Montreal 36
Des Moines 35
Frankfurt am Main 34
Ningbo 33
Mexico City 31
The Dalles 28
Brooklyn 27
Council Bluffs 27
Taizhou 27
Chennai 26
Zhengzhou 26
Falls Church 24
Salt Lake City 24
Stockholm 24
Turku 24
Shenzhen 23
Atlanta 22
Denver 22
Milan 22
Rio de Janeiro 22
Haikou 21
Kilburn 21
Norwalk 21
Tampa 19
Casablanca 18
Wuppertal 18
Nuremberg 17
Auburn Hills 16
Dong Ket 16
Johannesburg 16
Manchester 16
Ankara 15
Pesaro 15
Orange 14
Phoenix 14
Totale 33.777
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Nome #
1,3 dideazaadenosine is a mitogen for cultured mammalian cells. 3.218
Intracellular dehydroascorbic acid inhibits SVCT2-dependent transport of ascorbic acid in mitochondria 430
Superoxide dictates the mode of U937 cell ascorbic acid uptake and prevents the enhancing effects of the vitamin to otherwise non-toxic levels of reactive oxygen/nitrogen species 420
Mitochondrial ascorbic acid prevents mitochondrial O2.- formation, an event critical for U937 cell apoptosis induced by arsenite through both autophagic-dependent and independent mechanisms 381
U937 cell apoptosis induced by arsenite is prevented by low concentrations of mitochondrial ascorbic acid with hardly any effect mediated by the cytosolic fraction of the vitamin 324
A moderate decline in U937 cell GSH levels triggers PI3 kinase/Akt-dependent Bad phosphorylation, thereby preventing an otherwise prompt apoptotic response 302
A novel mechanism, uniquely dependent on mitochondrial calcium accumulation, whereby peroxynitrite promotes formation of superoxide/hydrogen peroxide and the ensuing strand scission of genomic DNA 294
A novel biological role of dehydroascorbic acid: Inhibition of Na+-dependent transport of ascorbic acid. 292
Sodium-dependent transport of ascorbic acid in U937 cell mitochondria. 289
The role of arachidonic acid in the regulation of nitric oxide synthase isoforms by HIV gp120 protein in astroglial cells 289
Apoptosis of human lymphocytes in the absence or presence of internucleosomal DNA cleavage 285
Apoptosis and necrosis following exposure of U937 cells to increasing concentrations of hydrogen peroxide: the effect of the poly(ADP-ribose)polymerase inhibitor 3-aminobenzamide. 282
The mitochondrial transporter of ascorbic acid functions with high affinity in the presence of low millimolar concentrations of sodium and in the absence of calcium and magnesium 281
5-Hydroxyeicosatetraenoic acid is a key intermediate of the arachidonate-dependent protective signaling in monocytes/macrophages exposed to peroxynitrite. 279
Arachidonic acid induces calcium-dependent mitochondrial formation of species promoting strand scission of genomic DNA 278
Mitochondrial ascorbic acid is responsible for enhanced susceptibility of U937 cells to the toxic effects of peroxynitrite 278
Arsenite induces DNA damage via mitochondrial ROS and induction of mitochondrial permeability transition 274
Mitochondria accumulate large amounts of quercetin: prevention of mitochondrial damage and release upon oxidation of the extramitochondrial fraction of the flavonoid 271
Calcium signals between the ryanodine receptor- and mitochondria critically regulate the effects of arsenite on mitochondrial superoxide formation and on the ensuing survival vs apoptotic signaling 270
Analogues of benzamide as poly(ADP-ribose)transferase inhibitors: a study on structure activity relationships. 265
Dexamethasone Promotes Toxicity in U937 Cells Exposed to Otherwise Non-toxic Concentrations of Peroxynitrite: Pivotal Role for Lipocortin 1 Mediated Inhibition of Cytosolic Phospholipase A2 262
Isolation and preliminary characterization of a Chinese hamster ovary cell line with high-degree resistance to hydrogen peroxide. 257
Direct excision of 50 Kb pair DNA fragments from megabase-sized fragments produced during apoptotic cleavage of genomic DNA. 257
Cytotoxic impact of DNA single vs double strand breaks in oxidatively injured cells 256
Meprobamate/morphine interactions on avoidance and escape behaviour in rats. 255
The study of the mechanism of arsenite toxicity in respiration-deficient cells reveals that NADPH oxidase-derived superoxide promotes the same downstream events mediated by mitochondrial superoxide in respiration-proficient cells 254
Assessing bad sub-cellular localization under conditions associated with prevention or promotion of mitochondrial permeability transition-dependent toxicity. 251
Cyclic GMP-dependent inhibition of acid sphingomyelinase by nitric oxide: an early step in protection against apoptosis. 250
A novel nonsense mutation in the APTX gene associated with delayed DNA single-strand break removal fails to enhance sensitivity to different genotoxic agents. 250
Cross-resistance to heavy metals in hydrogen peroxide-resistant CHO cell variants. 248
Differentiation-associated loss of ryanodine receptors: a strategy adopted by monocytes/macrophages to prevent the DNA single-strand breakage induced by peroxynitrite. 248
Simultaneous determination of DNA double strand breaks and DNA fragment size in cultured mammalian cells exposed to hydrogen peroxide/histidine or etoposide with CHEF electrophoresis. 246
Action of cystine in the cytotoxic response of Escherichia coli cells exposed to hydrogen peroxide. 245
U937 cell necrosis mediated by peroxynitrite is not caused by depletion of ATP and is prevented by arachidonate via an ATP-dependent mechanism. 245
Arachidonic acid: a key molecule for astrocyte survival to peroxynitrite. 244
Analysis of metal-induced DNA lesions and DNA-repair replication in mammalian cells. 243
The arachidonate-dependent survival signaling preventing toxicity in monocytes/macrophages exposed to peroxynitrite. 242
Low levels of hydrogen peroxide and L-histidine induce DNA double-strand breakage and apoptosis. 242
The L-histidine-mediated enhancement of hydrogen peroxide-induced DNA double strand breakage and cytotoxicity does not involve metabolic processes. 242
Adriamycin does not affect the repair of X-ray induced DNA single strand breaks. 242
Arsenite-induced mitochondrial superoxide formation: time and concentration requirements for the effects of the metalloid on the endoplasmic reticulum and mitochondria 241
Intramitochondrial Ascorbic Acid Enhances the Formation of Mitochondrial Superoxide Induced by Peroxynitrite via a Ca(2+)-Independent Mechanism 241
The induction/loss of the oxidant-resistant phenotype of Chinese hamster ovary (CHO) cell variants does not correlate with sensitivity to DNA single strand breakage by hydrogen peroxide. 240
Characterization of two novel SETX mutations in AOA2 patients reveals aspects of the pathophysiological role of senataxin. 239
The arachidonate-dependent cytoprotective signaling evoked by peroxynitrite is a general response of the monocyte/macrophage lineage 239
[Aryloxy- and arylthioalkylamine hypolipidemic agents] 238
The dual role of mitochondrial superoxide in arsenite toxicity: Signaling at the boundary between apoptotic commitment and cytoprotection 238
Studies with low micromolar levels of ascorbic and dehydroascorbic acid fail to unravel a preferential route for vitamin C uptake and accumulation in U937 cells 237
3-Aminobenzamide inhibition of protein kinase C at a cellular level. 237
A method for disposing of lysates from cells analyzed for DNA damage by filter elution assay. 236
ERK1/2 regulates two sequential steps promoting monocyte survival to peroxynitrite. 236
Inhibition of complex III promotes loss of Ca2+ dependence for mitochondrial superoxide formation and permeability transition evoked by peroxynitrite. 236
Differentiation of Promonocytic U937 Cells to Monocytes Is Associated with Reduced Mitochondrial Transport of Ascorbic Acid 236
Analysis of the induction of alkali sensitive sites in the DNA by chromate and other agents that induce single strand breaks. 236
Modulation of the oxidative response of cultured mammalian cells by L-histidine. 235
The effect of hydrogen peroxide/L-histidine-induced DNA single- vs. double-strand breaks on poly(ADP-ribose)polymerase. 235
Evidence for separate mechanisms of cytotoxicity in mammalian cells treated with hydrogen peroxide in the absence or presence of L-histidine 231
Novel SETX variants in a patient with ataxia, neuropathy, and oculomotor apraxia are associated with normal sensitivity to oxidative DNA damaging agents 231
Crosstalk between ERO1α and ryanodine receptor in arsenite-dependent mitochondrial ROS formation 231
L-glutamine prevents the L-histidine-mediated enhancement of hydrogen peroxide-induced cytotoxicity. 230
AG8 cells, which are highly resistant to hydrogen peroxide, display collateral sensitivity to the combination of hydrogen peroxide and L-histidine. 227
Osmotically driven radial diffusion of single-stranded DNA fragments on an agarose bed as a convenient measure of DNA strand scission. 226
Survival pathways triggered by peroxynitrite in cells belonging to the monocyte/macrophage lineage 225
Prevention of necrosis and activation of apoptosis in oxidatively injured human myeloid leukemia U937 cells. 225
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. 224
Arachidonic acid inhibits neuronal nitric oxide synthase elicited by proinflammatory stimuli and promotes astrocyte survival with both exogenous and endogenous peroxynitrite via different mechanisms. 224
The antioxidant butylated hydroxytoluene induces apoptosis in human U937 cells: the role of hydrogen peroxide and altered redox state. 224
L-histidine-mediated enhancement of hydrogen peroxide-induced cytotoxicity: relationships between DNA single/double strand breakage and cell killing. 220
A downstream role for protein kinase C alpha in the cytosolic phospholipase A2-dependent protective signalling mediated by peroxynitrite in U937 cells. 219
Structural requirements for inhibitors of poly(ADP-ribose) polymerase. 217
Peroxynitrite damages U937 cell DNA via the intermediate formation of mitochondrial oxidants. 217
SVCT2-DEPENDENT PLASMA AND MITOCHONDRIAL MEMBRANE TRANSPORT OF ASCORBIC ACID IN DIFFERENTIATING MYOBLASTS 217
Calcium chelator Quin 2 prevents hydrogen-peroxide-induced DNA breakage and cytotoxicity. 216
Effect of 3-aminobenzamide on DNA strand-break rejoining and cytotoxicity in CHO cells treated with hydrogen peroxide. 215
Quercetin prevents DNA single strand breakage and cytotoxicity caused by tert-butylhydroperoxide: free radical scavenging versus iron chelating mechanism. 214
Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals 214
Cell signalling and cytotoxicity by peroxynitrite. 212
Susceptibility of rat astrocytes to DNA strand scission induced by activation of NADPH oxidase and collateral resistance to the effects of peroxynitrite. 211
Peroxynitrite stimulates the activity of cytosolic phospholipase A2 in U937 cells: the extent of arachidonic acid formation regulates the balance between cell survival or death. 210
Products of the phospholipase A2 pathway mediate the dihydrorhodamine fluorescence response evoked by endogenous and exogenous peroxynitrite in PC12 cells. 209
Peroxynitrite-induced mitochondrial translocation of PKCalpha causes U937 cell survival. 209
Substituted Benzamides as Poly(ADP-Ribose) transferase Inhibitors: Development of new Derivatives by using Computer Graphics Techniques 207
Plant-derived phenolic compounds prevent the DNA single-strand breakage and cytotoxicity induced by tert-butylhydroperoxide via an iron-chelating mechanism. 207
ERK1/2-dependent regulation of U937 cell survival after exposure to peroxynitrite. 207
DOWNREGULATION OF NITRIC OXIDE FORMATION BY CYTOSOLIC PHOSPHOLIPASE A2-RELEASED ARACHIDONIC ACID. 207
Cell-density-dependent regulation of ATP levels during the growth cycle of cultured Chinese Hamster Ovary cells 205
Pivotal Role of Arachidonic Acid in the Regulation of Neuronal Nitric Oxide Synthase Activity and Inducible Nitric Oxide Synthase Expression in Activated Astrocytes 203
Modulation of muscarinic receptor-stimulated phosphoinositide breakdown by sulfhydryl group modification is a general response in different rat brain regions and depends on the stage of brain development. 203
Randomly distributed DNA single strand breaks are not lethal for mammalian cells. 203
DNA breakage caused by hydrogen peroxide produced during the metabolism of 2-methyl-1,4-naphthoquinone (menadione) does not contribute to the cytotoxic action of the quinone. 203
Delayed formation of hydrogen peroxide mediates the lethal response evoked by peroxynitrite in U937 cells 202
Use of mammalian DNA repair-deficient mutants to assess the effects of toxic metal compounds on DNA. 202
Hydrogen peroxide-and fetal bovine serum-induced DNA synthesis in vascular smooth muscle cells: positive and negative regulation by protein kinase C isoforms. 202
Hydrogen peroxide cytotoxicity under conditions of normal or reduced catalase activity in H2O2-sensitive and -resistant Chinese hamster ovary (CHO) cell variants. 201
Differential effect of the amino acid cystine in cultured mammalian and bacterial cells exposed to oxidative stress. 200
Role of Bcl-2 in the arachidonate-mediated survival signaling preventing mitochondrial permeability transition-dependent U937 cell necrosis induced by peroxynitrite 200
TNFa enhances the DNA single-strand breakage induced by the short-chain lipid hydroperoxide analogue tert-butylhydroperoxide via ceramide-dependent inhibition of complex III followed by enforced superoxide and hydrogen peroxide formation 197
Electron transport-mediated wasteful consumption of NADH promotes the lethal response of U937 cells to tert-butylhydroperoxide. 197
tert-Butylhydroperoxide induces peroxynitrite-dependent mitochondrial permeability transition leading PC12 cells to necrosis 197
ANALOGUES OF BENZAMIDE CONTAINING A SULPHUR ATOM AS POLY(ADP-ribose)TRANSFERASE INHIBITORS. 196
Totale 27.118
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Categoria #
all - tutte 153.994
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 153.994
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.090 0 0 0 0 0 0 0 0 0 361 515 214
2021/20222.605 281 288 248 359 79 87 137 165 154 201 49 557
2022/20233.237 337 142 32 404 353 715 9 227 560 101 240 117
2023/2024882 113 71 69 116 86 215 34 46 2 56 5 69
2024/20253.669 123 267 571 161 103 333 497 325 513 207 283 286
2025/20269.863 588 1.089 1.486 1.268 621 528 1.086 265 2.452 480 0 0
Totale 45.056