IRIS
PIERSANTI, GIOVANNI
 Distribuzione geografica
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Continente #
NA - Nord America 9.327
EU - Europa 5.370
AS - Asia 1.357
OC - Oceania 19
SA - Sud America 9
AF - Africa 4
Continente sconosciuto - Info sul continente non disponibili 3
Totale 16.089
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Nazione #
US - Stati Uniti d'America 9.297
GB - Regno Unito 1.814
IT - Italia 1.548
CN - Cina 960
UA - Ucraina 754
SE - Svezia 408
FI - Finlandia 283
DE - Germania 220
TR - Turchia 198
IE - Irlanda 155
KR - Corea 59
IN - India 54
FR - Francia 48
RU - Federazione Russa 48
JP - Giappone 34
CA - Canada 27
BE - Belgio 23
AU - Australia 18
VN - Vietnam 15
CH - Svizzera 13
PL - Polonia 11
HK - Hong Kong 9
IR - Iran 8
NL - Olanda 8
RO - Romania 7
PT - Portogallo 6
BR - Brasile 5
HR - Croazia 5
CL - Cile 4
ID - Indonesia 4
PK - Pakistan 4
AE - Emirati Arabi Uniti 3
BG - Bulgaria 3
ES - Italia 3
EU - Europa 3
SG - Singapore 3
AT - Austria 2
MD - Moldavia 2
PA - Panama 2
RS - Serbia 2
SA - Arabia Saudita 2
BD - Bangladesh 1
CY - Cipro 1
EE - Estonia 1
EG - Egitto 1
GR - Grecia 1
HU - Ungheria 1
IQ - Iraq 1
IS - Islanda 1
LK - Sri Lanka 1
LU - Lussemburgo 1
MA - Marocco 1
ME - Montenegro 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
SI - Slovenia 1
TG - Togo 1
ZA - Sudafrica 1
Totale 16.089
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Città #
Southend 1.629
Fairfield 1.461
Woodbridge 1.392
Houston 881
Ann Arbor 827
Ashburn 623
Seattle 599
Jacksonville 590
Chandler 580
Cambridge 561
Wilmington 476
Urbino 462
Nanjing 292
Izmir 190
Dublin 151
Helsinki 137
New York 101
Nanchang 92
Princeton 92
Beijing 89
San Mateo 81
Shenyang 71
Tianjin 66
Hebei 65
San Diego 59
Changsha 58
Seongnam 57
Jiaxing 49
Milan 44
London 43
Rome 42
Bremen 40
Kunming 37
Boardman 35
Velikiy Novgorod 31
Jinan 28
San Francisco 28
Düsseldorf 26
Brussels 22
Munich 17
Toronto 17
Hangzhou 16
Augusta 15
Ancona 14
Dong Ket 14
Ningbo 14
Zhengzhou 14
Jesi 12
Latina 12
Bologna 11
Mülheim 11
Norwalk 11
Shanghai 11
Portland 10
Redwood City 10
Wuppertal 10
Auburn Hills 9
Changchun 9
Prescot 9
Acton 8
Haikou 8
Kilburn 8
Fano 7
Guangzhou 7
Indiana 7
Leawood 7
Melbourne 7
Avola 6
Borås 6
Canberra 6
Enterprise 6
Gioia del Colle 6
Lanzhou 6
Los Angeles 6
Monte Porzio 6
Montelupo Fiorentino 6
Sassuolo 6
Turin 6
Angri 5
Baranzate 5
Castelbellino 5
Core 5
Council Bluffs 5
Des Moines 5
Naples 5
San Giorgio A Cremano 5
Stockholm 5
Ardabil 4
Bobigny 4
Edinburgh 4
Florence 4
Forlì 4
Lisbon 4
Manchester 4
Mumbai 4
New Bedfont 4
Rieti 4
Rimini 4
San Colombano al Lambro 4
Sydney 4
Totale 12.575
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Nome #
Targeting SARS-CoV-2 by synthetic dual-acting thiol compounds that inhibit Spike/ACE2 interaction and viral protein production 435
Iridium-Catalyzed Direct Synthesis of Tryptamine Derivatives from Indoles: Exploiting N-Protected β-Amino Alcohols as Alkylating Agents 309
Observations concerning the synthesis of tryptamine homologues and branched tryptamine derivatives via the borrowing hydrogen process: synthesis of psilocin, bufotenin, and serotonin 271
Synthesis of Boron- and Silicon-Containing Amino Acids through Copper-Catalysed Conjugate Additions to Dehydroalanine Derivatives 265
Palladium(II)-Catalyzed Cross-Dehydrogenative Coupling (CDC) of N-Phthaloyl Dehydroalanine Esters with Simple Arenes: Stereoselective Synthesis of Z-Dehydrophenylalanine Derivatives 251
One-Pot Synthesis of Biheterocycles Based on Indole and Azole Scaffolds Using Tryptamines and 1,2-Diaza-1,3-dienes as Building Blocks 247
Synthesis of (−)-Epi-Indolactam V by an Intramolecular Buchwald–Hartwig C–N Coupling Cyclization Reaction 244
Synthesis of 2-substituted tryptophans via a C3- to C2-alkyl migration 243
Synthesis of Tryptamine Derivatives via a Direct, One-Pot Reductive Alkylation of Indoles 237
Palladium(II)-Catalyzed Intramolecular Oxidative C−H/C−H Cross-Coupling Reaction of C3,N-linked Biheterocycles: Rapid Access to Polycyclic Nitrogen Heterocycles 235
Iron-Catalyzed Direct C3-Benzylation of Indoles with Benzyl Alcohols through Borrowing Hydrogen 232
Potent, Metabolically Stable 2-Alkyl-8-(2H-1,2,3-triazol-2-yl)-9H-adenines as Adenosine A2A Receptor Ligands 228
Derivatizzazione one-pot di indoli per la sintesi di triptofani, pirroloindoline, bis-indoli & co 226
Divergent synthesis of novel 9-deazaxanthine derivatives via late-stage cross-coupling reactions 224
A simple, modular synthesis of C4-substituted tryptophan derivatives 224
Tricyclic Alkylamides as Melatonin Receptor Ligands with Antagonist or Inverse Agonist Activity 222
Organocatalyzed coupling of indoles with dehydroalanine esters: synthesis of bis(indolyl)propanoates and indolacrylates 222
Switchable reactivity of acylated alpha, beta-dehydroamino ester in the Friedel-Crafts alkylation of indoles by changing the Lewis acid. 222
An improved synthesis of cis-4-phenyl-2-propionamidotetralin (4-P-PDOT): a selective MT2 melatonin receptor antagonist. 221
Enantioselective Total Synthesis of (−)-Acylfulvene and (−)-Irofulven 219
Direct, One-Pot Reductive Alkylation of Anilines with Functionalized Acetals Mediated by Triethylsilane and TFA. Straightforward Route for Unsymmetrically Substituted Ethylenediamine 218
Synthesis of (±)-cis-Clavicipitic Acid by a Rh(I)-Catalyzed Intramolecular Imine Reaction 218
Synthesis of benzo[1,2-d;3,4-d’]diimidazole and 1H-pyrazolo[4,3-b]pyridine as putative A2A receptor antagonists 217
Direct, Regioselective, and Chemoselective Preparation of Novel Boronated Tryptophans by Friedel–Crafts Alkylation 216
Synthesis of Tetrahydropyridazine Amino Acid Derivatives by a Formal [4+2| Cycloaddition Reaction of 1,​2-​Diaza-​1,​3-​dienes with Dehydroalanine Esters 214
Synthesis and Configuration Determination of All Enantiopure Stereoisomers of the Melatonin Receptor Ligand 4-Phenyl-2-propionamidotetralin using an Expedient Optical Resolution of 4-Phenyl-2-tetralone 212
Development of a practical and sustainable strategy for the synthesis of ST1535 by an iron-catalyzed Kumada cross-coupling reaction 210
A Novel One-Pot Approach of Hexahydropyrrolo[2,3-b]indole Nucleus by a cascade addition/cyclization strategy: Synthesis of (±)-Esermethole 209
2-n-Butyl- 9-methyl-8-(1,2,3)triazol-2-yl-9H-purin-6-ylamine and Analogues as A2A Adenosine Receptor Antagonists. Design, Synthesis, and Pharmacological Characterization 209
Synthesis and Biological Evaluation of Metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), A Potent Antagonist of the A2AAdenosine Receptor for the Treatment of Parkinson’s Disease 208
New coumarin-urea based receptor for anions: a selective off-on fluorescence response to fluoride 203
Organocatalytic synthesis of α-quaternary amino acid derivatives via aza-Friedel–Crafts alkylation of indoles with simple α-amidoacrylates 203
Metodo di sintesi di derivati del glutatione [Method for the synthesis of glutathione derivatives] 197
Enantioselective total synthesis of (-)-acylfulvene and (-)-irofulven. 195
Synthesis, binding and fluorescence studies of a new neutral H-bonding receptor for anions based on 3,5-bis(trifluoromethyl)phenylurea 194
Polycyclic Indolines by Acid-Mediated Intramolecular Dearomative Strategy: Reversing Indole Reactivity in the Pictet‒Spengler-Type Reaction 193
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 187
New family of polyamine macrocycles containing 2,5-diphenyl[1,3,4]oxadiazole as a signaling unit. Synthesis, acid–base and spectrophotometric properties 186
Short and straightforward synthesis of 1,7-dimethyl-1,4,7,10-tetraazacyclododecane 184
An efficient synthesis of the cyclic form of scalemic 2,4-di-epi-polyoxamic acid exploiting the hetero Diels-Alder approach. 183
Direct preparation of unsymmetrical difunctionalized cyclen derivatives by an Ugi multicomponent reaction 180
Facile Synthesis of @-Tide-Strand Peptidomimetics: Improved Assembly in Solution and on Solid Phase 179
An efficient, economical synthesis of hydroxytyrosol and its protected forms via Baeyer–Villiger oxidation 178
Stereoselective synthesis of chiral 3,4,5-trisubstituted 1,5-dihydropyrrol-2-ones from azadienes. 176
Organocatalytic Aza-Friedel-Crafts/Lactonization Domino Reaction of Naphthols and Phenols with 2-Acetamidoacrylate to Naphtho- and Benzofuranones Bearing a Quaternary Center at the C3 Position 175
C3-Alkylation of indoles and oxindoles by alcohols by means of borrowing hydrogen methodology 174
Stereochemical aspects of a two-step Staudinger reaction - asymmetric synthesis of chiral azetidine-2-ones. 173
Synthesis of (E)-8-(3-Chlorostyryl)caffeine Analogues Leading to 9-Deazaxanthine Derivatives as Dual A2AAntagonists/MAO-B Inhibitors 173
A Trans-Stereoselective Synthesis of 3-Halo-4-alkyl(aryl)-NH-azetidin-2-ones. 173
New branched macrocyclic ligand and its side-arm, two urea-based receptors for anions: Synthesis, binding studies and crystal structure 172
Direct B-alkyl Suzuki-Miyaura cross-coupling of 2-halopurines. Practical synthesis os ST1535, a potent adenosine A2A receptor antagonist 171
Conformation by NMR of two tetralin-based receptor ligands 169
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 168
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 167
5-(2-Ethyl-phenyl)-3-(3-methoxy-phenyl)-1H-[1,2,4]triazole (DL-111-IT ) and related compounds induce morphological apoptotic patterns in cultures of human tumor cell lines 164
Observations in the synthesis of the core of the antitumor illudins via an enyne ring closing metathesis cascade 164
Divergent reactions of oxindoles with amino alcohols via the borrowing hydrogen process: oxindole ring opening vs. C3 alkylation 163
Large-Scale Preparation of N-Butanoyl-l-glutathione (C4-GSH) 163
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 162
Diastereo- and enantioselective hydrogenation of a challenging enamide derived from 4-phenyl-2-tetralone: an appealing shortcut towards enantiopure cis-2-aminotetraline derivatives 162
Brønsted Acid-Catalyzed Bisindolization of α-amido acetals: Synthesis and Anticancer activity of bis(indolyl)ethanamino derivatives 160
Neutral urea-based receptors for phosphates: synthesis and spectrophotometric studies 159
Concise and Convergent Enantioselective Total Syntheses of (+)- and (-)-Fumimycin 157
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 157
Total Synthesis of (-)-Clavicipitic Acid via γ,γ-Dimethylallyltryptophan (DMAT) and Chemoselective C-H Hydroxylation 149
Strategies leading to MT2 selective melatonin receptor antagonists 142
Oxidated derivatives of triazolylpurines useful as ligands of the adenosine A2A receptor and their use as medicaments 139
N-alchil-O-arilcarbammati come inibitori delle idrolasi delle ammidi degli acidi grassi (FAAH): aspetti meccanicistici 137
Single‐Step Synthesis of Dehydroalanine Derivatives via a Brønsted Acid‐Catalyzed Multicomponent Reaction 135
Quantifying the Interactions that Contribute to beta-Hairpin Folding 132
DERIVATIVES OF TRIAZOLYL-IMIDAZOPYRIDINE AND OF THE TRIAZOLYLPURINES USEFUL AS LIGANDS OF THE ADENOSINE A2a RECEPTOR AND THEIR USE AS MEDICAMENTS. 128
Design, SAR and Biological Activity of a New Class of FAAH Inhibitors: Cyclohexyl Carbamic Acid Biphenyl-3-yl Esters 128
Derivatives of triazoly-imidazopyridine useful as ligands of the adenosine A2a receptor ant their use as medicaments 127
Hydroxytyrosol derivates prevent apoptosis and autophagy. 125
New Receptor For Anions: Signalling Ureido Side-Arms Preorganized On Polyamine Scaffold 124
A Versatile Biomimetic Approach to Diindolylmethane Derivatives as Potential Anticancer Agents 119
Protective action of hydroxytyrosol derivates vs apoptosis: apreliminary study. 118
2-n-butyl-9-methyl-8-(1,2,3)triazol-2yl-9H-purin-6-yl-amine (ST 1535) and analogs as A2a Adenosine receptor antagonists. Design, synthesis and pharmacological characterization 114
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign 111
Structure-Activity Relationships of Alkylcarbamic Acid Aryl Esters, as Fatty Acid Amide Hydrolase Inhibitors 109
Design, Synthesis and SAR of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acids Amide Hydrolase Inhibitors 107
Mass Spectrometry and Pharmacology Activity: The Case of Carbamic Analogs 97
Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamates FAAH inhibitors 97
The Collisional Behavior of ESI-Generated Protonated Molecules of Some Carbamate Bioisosters and its Relationship with their Biological Activity 92
Novel, Chiral, and Enantiopure C2‐Symmetric Thioureas Promote Asymmetric Protio‐Pictet‐Spengler Reactions by Anion‐Binding Catalysis 91
Synthesis and Pharmacological Characterization of Potent and Selective Inhibitors of Fatty Acid Amidohydrolase (FAAH) 88
General synthesis of unnatural 4-, 5-, 6-, and 7-bromo-d-tryptophans by means of a regioselective indole alkylation 86
Receptors for Anions Based On Signalling Bisureas 82
Recent advances in "hydride reductions":regio-,chemo-, and stereoselective transformations 69
Synthesis and Reactivity of Uhle’s Ketone and Its Derivatives 69
Esteri bifenil-3-ilici dell'acido cicloesilcarbammico quali inibitori dell'enzima FAAH: sintesi, QSAR e modellistica molecolare 66
Concise catalytic asymmetric synthesis of (R)-4-amino Uhle's ketone 62
Dithiol Based on L-Cysteine and Cysteamine as a Disulfide-Reducing Agent 55
Asymmetric Total Synthesis of All Rugulovasine Stereoisomers and Preliminary Evaluation of Their Biological Properties 44
Asymmetric Alkylation of Cyclic Ketones with Dehydroalanine via H-Bond-Directing Enamine Catalysis: Straightforward Access to Enantiopure Unnatural α-Amino Acids 37
Synthesis and Fluorescence Properties of 4-Cyano and 4-Formyl Melatonin as Putative Melatoninergic Ligands 25
Photoredox catalysis enabling decarboxylative radical cyclization of γ,γ-dimethylallyltryptophan (DMAT) derivatives: formal synthesis of 6,7-secoagroclavine 21
A Short Synthesis of (−)‐6,7‐Secoagroclavine via Metal‐Free Reductive Coupling 18
General Access to Clavine Alkaloids via a Rhodium(I)‐Catalyzed Diastereoselective Hayashi‐Miyaura Reaction 16
Enantioselective organocatalytic strategies to noncanonical α‐amino acids 15
Totale 16.346
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Categoria #
all - tutte 45.287
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 45.287
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019867 0 0 0 0 0 0 0 0 0 122 264 481
2019/20203.865 567 126 243 831 284 366 383 326 257 224 140 118
2020/20212.562 98 248 224 197 194 155 311 144 345 257 281 108
2021/20221.349 126 186 128 138 20 54 70 77 65 90 64 331
2022/20232.167 179 107 54 231 159 347 11 161 435 144 230 109
2023/2024579 56 45 35 90 34 125 28 44 89 33 0 0
Totale 16.350