IRIS
PIERSANTI, GIOVANNI
 Distribuzione geografica
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Continente #
NA - Nord America 9.638
EU - Europa 5.601
AS - Asia 1.845
OC - Oceania 19
SA - Sud America 10
AF - Africa 4
Continente sconosciuto - Info sul continente non disponibili 3
Totale 17.120
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Nazione #
US - Stati Uniti d'America 9.602
GB - Regno Unito 1.818
IT - Italia 1.660
CN - Cina 1.162
UA - Ucraina 754
SE - Svezia 409
FI - Finlandia 288
TR - Turchia 266
DE - Germania 225
SG - Singapore 206
IE - Irlanda 155
RU - Federazione Russa 127
KR - Corea 60
IN - India 59
FR - Francia 51
JP - Giappone 35
CA - Canada 30
BE - Belgio 23
AU - Australia 18
NL - Olanda 16
CH - Svizzera 15
VN - Vietnam 15
PL - Polonia 12
HK - Hong Kong 10
IR - Iran 8
RO - Romania 8
PT - Portogallo 6
BR - Brasile 5
HR - Croazia 5
PK - Pakistan 5
AE - Emirati Arabi Uniti 4
BG - Bulgaria 4
CL - Cile 4
ID - Indonesia 4
PA - Panama 4
CZ - Repubblica Ceca 3
ES - Italia 3
EU - Europa 3
GR - Grecia 3
AT - Austria 2
HU - Ungheria 2
LT - Lituania 2
MD - Moldavia 2
RS - Serbia 2
SA - Arabia Saudita 2
TW - Taiwan 2
AM - Armenia 1
BD - Bangladesh 1
CR - Costa Rica 1
CY - Cipro 1
DK - Danimarca 1
EE - Estonia 1
EG - Egitto 1
IQ - Iraq 1
IS - Islanda 1
KG - Kirghizistan 1
LK - Sri Lanka 1
LU - Lussemburgo 1
MA - Marocco 1
ME - Montenegro 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PE - Perù 1
PH - Filippine 1
SI - Slovenia 1
TG - Togo 1
ZA - Sudafrica 1
Totale 17.120
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Città #
Southend 1.629
Fairfield 1.461
Woodbridge 1.392
Houston 881
Ann Arbor 827
Ashburn 626
Seattle 601
Jacksonville 590
Chandler 580
Cambridge 561
Urbino 507
Wilmington 476
Nanjing 292
Boardman 190
Izmir 190
Singapore 177
Dublin 151
Helsinki 141
Beijing 105
New York 101
Nanchang 92
Princeton 92
San Mateo 81
Shenyang 72
Tianjin 66
Hebei 65
Milan 60
San Diego 59
Changsha 58
Seongnam 57
Jiaxing 52
Istanbul 51
Rome 50
London 43
Bremen 40
Kunming 37
Shanghai 31
Velikiy Novgorod 31
Moscow 30
Jinan 29
San Francisco 28
Düsseldorf 26
Santa Clara 24
Brussels 22
Munich 20
Toronto 19
Guangzhou 17
Hangzhou 17
Augusta 15
Los Angeles 15
Ancona 14
Dong Ket 14
Ningbo 14
Zhengzhou 14
Bologna 13
Jesi 12
Latina 12
Mülheim 11
Norwalk 11
Portland 10
Redwood City 10
Wuppertal 10
Auburn Hills 9
Changchun 9
Prescot 9
Acton 8
Haikou 8
Kilburn 8
Shenzhen 8
Fano 7
Indiana 7
Leawood 7
Manchester 7
Melbourne 7
Turin 7
Avola 6
Borås 6
Canberra 6
Council Bluffs 6
Enterprise 6
Gioia del Colle 6
Lanzhou 6
Monte Porzio 6
Montelupo Fiorentino 6
Naples 6
Sassuolo 6
Stockholm 6
Angri 5
Baranzate 5
Castelbellino 5
Core 5
Des Moines 5
Mumbai 5
San Giorgio A Cremano 5
Tokyo 5
Ardabil 4
Bari 4
Bobigny 4
Chicago 4
Edinburgh 4
Totale 13.155
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Nome #
Targeting SARS-CoV-2 by synthetic dual-acting thiol compounds that inhibit Spike/ACE2 interaction and viral protein production 459
Iridium-Catalyzed Direct Synthesis of Tryptamine Derivatives from Indoles: Exploiting N-Protected β-Amino Alcohols as Alkylating Agents 320
Observations concerning the synthesis of tryptamine homologues and branched tryptamine derivatives via the borrowing hydrogen process: synthesis of psilocin, bufotenin, and serotonin 284
Synthesis of Boron- and Silicon-Containing Amino Acids through Copper-Catalysed Conjugate Additions to Dehydroalanine Derivatives 276
Palladium(II)-Catalyzed Cross-Dehydrogenative Coupling (CDC) of N-Phthaloyl Dehydroalanine Esters with Simple Arenes: Stereoselective Synthesis of Z-Dehydrophenylalanine Derivatives 257
One-Pot Synthesis of Biheterocycles Based on Indole and Azole Scaffolds Using Tryptamines and 1,2-Diaza-1,3-dienes as Building Blocks 256
Derivatizzazione one-pot di indoli per la sintesi di triptofani, pirroloindoline, bis-indoli & co 254
Synthesis of (−)-Epi-Indolactam V by an Intramolecular Buchwald–Hartwig C–N Coupling Cyclization Reaction 251
Synthesis of 2-substituted tryptophans via a C3- to C2-alkyl migration 249
Synthesis of Tryptamine Derivatives via a Direct, One-Pot Reductive Alkylation of Indoles 248
Palladium(II)-Catalyzed Intramolecular Oxidative C−H/C−H Cross-Coupling Reaction of C3,N-linked Biheterocycles: Rapid Access to Polycyclic Nitrogen Heterocycles 245
Iron-Catalyzed Direct C3-Benzylation of Indoles with Benzyl Alcohols through Borrowing Hydrogen 242
An improved synthesis of cis-4-phenyl-2-propionamidotetralin (4-P-PDOT): a selective MT2 melatonin receptor antagonist. 236
Divergent synthesis of novel 9-deazaxanthine derivatives via late-stage cross-coupling reactions 236
A simple, modular synthesis of C4-substituted tryptophan derivatives 236
Potent, Metabolically Stable 2-Alkyl-8-(2H-1,2,3-triazol-2-yl)-9H-adenines as Adenosine A2A Receptor Ligands 235
Switchable reactivity of acylated alpha, beta-dehydroamino ester in the Friedel-Crafts alkylation of indoles by changing the Lewis acid. 231
Tricyclic Alkylamides as Melatonin Receptor Ligands with Antagonist or Inverse Agonist Activity 228
Organocatalyzed coupling of indoles with dehydroalanine esters: synthesis of bis(indolyl)propanoates and indolacrylates 228
Enantioselective Total Synthesis of (−)-Acylfulvene and (−)-Irofulven 226
Direct, Regioselective, and Chemoselective Preparation of Novel Boronated Tryptophans by Friedel–Crafts Alkylation 226
Synthesis of benzo[1,2-d;3,4-d’]diimidazole and 1H-pyrazolo[4,3-b]pyridine as putative A2A receptor antagonists 225
Synthesis and Configuration Determination of All Enantiopure Stereoisomers of the Melatonin Receptor Ligand 4-Phenyl-2-propionamidotetralin using an Expedient Optical Resolution of 4-Phenyl-2-tetralone 224
Direct, One-Pot Reductive Alkylation of Anilines with Functionalized Acetals Mediated by Triethylsilane and TFA. Straightforward Route for Unsymmetrically Substituted Ethylenediamine 223
Synthesis of (±)-cis-Clavicipitic Acid by a Rh(I)-Catalyzed Intramolecular Imine Reaction 223
A Novel One-Pot Approach of Hexahydropyrrolo[2,3-b]indole Nucleus by a cascade addition/cyclization strategy: Synthesis of (±)-Esermethole 222
Synthesis of Tetrahydropyridazine Amino Acid Derivatives by a Formal [4+2| Cycloaddition Reaction of 1,​2-​Diaza-​1,​3-​dienes with Dehydroalanine Esters 222
2-n-Butyl- 9-methyl-8-(1,2,3)triazol-2-yl-9H-purin-6-ylamine and Analogues as A2A Adenosine Receptor Antagonists. Design, Synthesis, and Pharmacological Characterization 219
Development of a practical and sustainable strategy for the synthesis of ST1535 by an iron-catalyzed Kumada cross-coupling reaction 218
Metodo di sintesi di derivati del glutatione [Method for the synthesis of glutathione derivatives] 217
Synthesis and Biological Evaluation of Metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), A Potent Antagonist of the A2AAdenosine Receptor for the Treatment of Parkinson’s Disease 214
New coumarin-urea based receptor for anions: a selective off-on fluorescence response to fluoride 211
Organocatalytic synthesis of α-quaternary amino acid derivatives via aza-Friedel–Crafts alkylation of indoles with simple α-amidoacrylates 208
Enantioselective total synthesis of (-)-acylfulvene and (-)-irofulven. 202
Polycyclic Indolines by Acid-Mediated Intramolecular Dearomative Strategy: Reversing Indole Reactivity in the Pictet‒Spengler-Type Reaction 201
Synthesis, binding and fluorescence studies of a new neutral H-bonding receptor for anions based on 3,5-bis(trifluoromethyl)phenylurea 200
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 197
An efficient synthesis of the cyclic form of scalemic 2,4-di-epi-polyoxamic acid exploiting the hetero Diels-Alder approach. 192
New family of polyamine macrocycles containing 2,5-diphenyl[1,3,4]oxadiazole as a signaling unit. Synthesis, acid–base and spectrophotometric properties 192
Short and straightforward synthesis of 1,7-dimethyl-1,4,7,10-tetraazacyclododecane 189
An efficient, economical synthesis of hydroxytyrosol and its protected forms via Baeyer–Villiger oxidation 189
Facile Synthesis of @-Tide-Strand Peptidomimetics: Improved Assembly in Solution and on Solid Phase 187
C3-Alkylation of indoles and oxindoles by alcohols by means of borrowing hydrogen methodology 186
Direct preparation of unsymmetrical difunctionalized cyclen derivatives by an Ugi multicomponent reaction 185
A Trans-Stereoselective Synthesis of 3-Halo-4-alkyl(aryl)-NH-azetidin-2-ones. 184
Stereoselective synthesis of chiral 3,4,5-trisubstituted 1,5-dihydropyrrol-2-ones from azadienes. 183
Direct B-alkyl Suzuki-Miyaura cross-coupling of 2-halopurines. Practical synthesis os ST1535, a potent adenosine A2A receptor antagonist 183
Organocatalytic Aza-Friedel-Crafts/Lactonization Domino Reaction of Naphthols and Phenols with 2-Acetamidoacrylate to Naphtho- and Benzofuranones Bearing a Quaternary Center at the C3 Position 183
New branched macrocyclic ligand and its side-arm, two urea-based receptors for anions: Synthesis, binding studies and crystal structure 181
Stereochemical aspects of a two-step Staudinger reaction - asymmetric synthesis of chiral azetidine-2-ones. 179
Conformation by NMR of two tetralin-based receptor ligands 179
Synthesis of (E)-8-(3-Chlorostyryl)caffeine Analogues Leading to 9-Deazaxanthine Derivatives as Dual A2AAntagonists/MAO-B Inhibitors 178
5-(2-Ethyl-phenyl)-3-(3-methoxy-phenyl)-1H-[1,2,4]triazole (DL-111-IT ) and related compounds induce morphological apoptotic patterns in cultures of human tumor cell lines 177
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 175
Observations in the synthesis of the core of the antitumor illudins via an enyne ring closing metathesis cascade 172
Divergent reactions of oxindoles with amino alcohols via the borrowing hydrogen process: oxindole ring opening vs. C3 alkylation 172
Concise and Convergent Enantioselective Total Syntheses of (+)- and (-)-Fumimycin 172
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 172
Brønsted Acid-Catalyzed Bisindolization of α-amido acetals: Synthesis and Anticancer activity of bis(indolyl)ethanamino derivatives 171
Large-Scale Preparation of N-Butanoyl-l-glutathione (C4-GSH) 171
Diastereo- and enantioselective hydrogenation of a challenging enamide derived from 4-phenyl-2-tetralone: an appealing shortcut towards enantiopure cis-2-aminotetraline derivatives 169
Neutral urea-based receptors for phosphates: synthesis and spectrophotometric studies 167
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 166
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 163
Total Synthesis of (-)-Clavicipitic Acid via γ,γ-Dimethylallyltryptophan (DMAT) and Chemoselective C-H Hydroxylation 153
Strategies leading to MT2 selective melatonin receptor antagonists 149
Oxidated derivatives of triazolylpurines useful as ligands of the adenosine A2A receptor and their use as medicaments 145
Single‐Step Synthesis of Dehydroalanine Derivatives via a Brønsted Acid‐Catalyzed Multicomponent Reaction 145
N-alchil-O-arilcarbammati come inibitori delle idrolasi delle ammidi degli acidi grassi (FAAH): aspetti meccanicistici 143
Quantifying the Interactions that Contribute to beta-Hairpin Folding 139
Derivatives of triazoly-imidazopyridine useful as ligands of the adenosine A2a receptor ant their use as medicaments 136
Hydroxytyrosol derivates prevent apoptosis and autophagy. 136
DERIVATIVES OF TRIAZOLYL-IMIDAZOPYRIDINE AND OF THE TRIAZOLYLPURINES USEFUL AS LIGANDS OF THE ADENOSINE A2a RECEPTOR AND THEIR USE AS MEDICAMENTS. 135
Design, SAR and Biological Activity of a New Class of FAAH Inhibitors: Cyclohexyl Carbamic Acid Biphenyl-3-yl Esters 133
2-n-butyl-9-methyl-8-(1,2,3)triazol-2yl-9H-purin-6-yl-amine (ST 1535) and analogs as A2a Adenosine receptor antagonists. Design, synthesis and pharmacological characterization 131
A Versatile Biomimetic Approach to Diindolylmethane Derivatives as Potential Anticancer Agents 131
New Receptor For Anions: Signalling Ureido Side-Arms Preorganized On Polyamine Scaffold 129
Protective action of hydroxytyrosol derivates vs apoptosis: apreliminary study. 125
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign 123
Structure-Activity Relationships of Alkylcarbamic Acid Aryl Esters, as Fatty Acid Amide Hydrolase Inhibitors 117
Design, Synthesis and SAR of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acids Amide Hydrolase Inhibitors 112
Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamates FAAH inhibitors 107
Mass Spectrometry and Pharmacology Activity: The Case of Carbamic Analogs 105
Novel, Chiral, and Enantiopure C2‐Symmetric Thioureas Promote Asymmetric Protio‐Pictet‐Spengler Reactions by Anion‐Binding Catalysis 101
The Collisional Behavior of ESI-Generated Protonated Molecules of Some Carbamate Bioisosters and its Relationship with their Biological Activity 99
General synthesis of unnatural 4-, 5-, 6-, and 7-bromo-d-tryptophans by means of a regioselective indole alkylation 98
Synthesis and Pharmacological Characterization of Potent and Selective Inhibitors of Fatty Acid Amidohydrolase (FAAH) 95
Receptors for Anions Based On Signalling Bisureas 86
Concise catalytic asymmetric synthesis of (R)-4-amino Uhle's ketone 80
Synthesis and Reactivity of Uhle’s Ketone and Its Derivatives 77
Esteri bifenil-3-ilici dell'acido cicloesilcarbammico quali inibitori dell'enzima FAAH: sintesi, QSAR e modellistica molecolare 75
Recent advances in "hydride reductions":regio-,chemo-, and stereoselective transformations 74
Dithiol Based on L-Cysteine and Cysteamine as a Disulfide-Reducing Agent 69
Asymmetric Total Synthesis of All Rugulovasine Stereoisomers and Preliminary Evaluation of Their Biological Properties 62
A Short Synthesis of (−)‐6,7‐Secoagroclavine via Metal‐Free Reductive Coupling 54
Asymmetric Alkylation of Cyclic Ketones with Dehydroalanine via H-Bond-Directing Enamine Catalysis: Straightforward Access to Enantiopure Unnatural α-Amino Acids 53
Enantioselective organocatalytic strategies to noncanonical α‐amino acids 49
General Access to Clavine Alkaloids via a Rhodium(I)‐Catalyzed Diastereoselective Hayashi‐Miyaura Reaction 42
Synthesis and Fluorescence Properties of 4-Cyano and 4-Formyl Melatonin as Putative Melatoninergic Ligands 40
Photoredox catalysis enabling decarboxylative radical cyclization of γ,γ-dimethylallyltryptophan (DMAT) derivatives: formal synthesis of 6,7-secoagroclavine 32
Totale 17.346
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Categoria #
all - tutte 57.773
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 57.773
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.448 0 0 0 0 0 0 383 326 257 224 140 118
2020/20212.562 98 248 224 197 194 155 311 144 345 257 281 108
2021/20221.349 126 186 128 138 20 54 70 77 65 90 64 331
2022/20232.167 179 107 54 231 159 347 11 161 435 144 230 109
2023/2024709 56 45 35 90 34 125 28 44 89 60 17 86
2024/2025910 87 85 372 143 80 139 4 0 0 0 0 0
Totale 17.390