IRIS
PIERSANTI, GIOVANNI
 Distribuzione geografica
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Continente #
NA - Nord America 11.161
EU - Europa 6.503
AS - Asia 3.182
SA - Sud America 297
AF - Africa 33
OC - Oceania 24
Continente sconosciuto - Info sul continente non disponibili 3
Totale 21.203
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Nazione #
US - Stati Uniti d'America 11.042
IT - Italia 1.906
GB - Regno Unito 1.882
CN - Cina 1.617
SG - Singapore 795
UA - Ucraina 759
SE - Svezia 425
RU - Federazione Russa 378
DE - Germania 327
FI - Finlandia 325
TR - Turchia 279
BR - Brasile 242
IE - Irlanda 157
VN - Vietnam 138
IN - India 115
FR - Francia 114
CA - Canada 71
KR - Corea 61
JP - Giappone 49
PL - Polonia 48
NL - Olanda 36
MX - Messico 30
BE - Belgio 27
HK - Hong Kong 26
AU - Australia 21
AR - Argentina 20
CH - Svizzera 17
ES - Italia 16
BD - Bangladesh 14
ZA - Sudafrica 13
ID - Indonesia 12
AE - Emirati Arabi Uniti 11
AT - Austria 11
EC - Ecuador 11
IR - Iran 9
LT - Lituania 9
CL - Cile 8
PK - Pakistan 8
RO - Romania 8
IQ - Iraq 7
BG - Bulgaria 6
HR - Croazia 6
PT - Portogallo 6
AM - Armenia 5
CZ - Repubblica Ceca 5
EG - Egitto 5
GR - Grecia 5
MA - Marocco 5
PA - Panama 5
PE - Perù 5
SA - Arabia Saudita 5
HU - Ungheria 4
UZ - Uzbekistan 4
VE - Venezuela 4
AZ - Azerbaigian 3
CR - Costa Rica 3
EU - Europa 3
KE - Kenya 3
KG - Kirghizistan 3
LV - Lettonia 3
MD - Moldavia 3
NO - Norvegia 3
PH - Filippine 3
PY - Paraguay 3
AL - Albania 2
BO - Bolivia 2
CY - Cipro 2
DO - Repubblica Dominicana 2
EE - Estonia 2
IL - Israele 2
IS - Islanda 2
JM - Giamaica 2
KZ - Kazakistan 2
LU - Lussemburgo 2
NI - Nicaragua 2
RS - Serbia 2
SM - San Marino 2
TH - Thailandia 2
TN - Tunisia 2
TT - Trinidad e Tobago 2
TW - Taiwan 2
BB - Barbados 1
BH - Bahrain 1
BW - Botswana 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
CO - Colombia 1
DK - Danimarca 1
GA - Gabon 1
GT - Guatemala 1
JO - Giordania 1
KH - Cambogia 1
KI - Kiribati 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
ME - Montenegro 1
MY - Malesia 1
NP - Nepal 1
NR - Nauru 1
NZ - Nuova Zelanda 1
Totale 21.197
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Città #
Southend 1.629
Fairfield 1.461
Woodbridge 1.392
Ashburn 991
Houston 896
Ann Arbor 827
Seattle 605
Jacksonville 590
Chandler 580
Cambridge 564
Urbino 556
Wilmington 476
Singapore 349
Nanjing 293
Dallas 265
Beijing 256
Boardman 191
Izmir 190
Dublin 153
New York 145
Helsinki 144
Los Angeles 115
Nanchang 92
Princeton 92
San Mateo 81
Munich 77
Milan 76
Tianjin 75
Shenyang 72
Rome 67
Hebei 65
Changsha 63
San Diego 59
Seongnam 57
London 53
Istanbul 52
Jiaxing 52
Moscow 52
Ho Chi Minh City 50
Santa Clara 49
Council Bluffs 42
Düsseldorf 42
Buffalo 41
Bremen 40
Kunming 37
Chicago 36
San Francisco 36
Warsaw 35
São Paulo 33
Shanghai 32
Velikiy Novgorod 31
Hanoi 30
Turku 30
Jinan 29
Chennai 28
Toronto 27
Brussels 26
Hangzhou 24
Montreal 24
Ancona 23
Denver 23
Brooklyn 22
Poplar 22
Bellaria-Igea Marina 21
Stockholm 21
Guangzhou 20
Hong Kong 19
Bologna 18
Tokyo 18
Augusta 17
Frankfurt am Main 16
Mexico City 15
Paris 15
Zhengzhou 15
Dong Ket 14
Lauterbourg 14
Manchester 14
Ningbo 14
Phoenix 14
Nuremberg 13
Atlanta 12
Jesi 12
Latina 12
Des Moines 11
Elk Grove Village 11
Johannesburg 11
Mülheim 11
Norwalk 11
Redondo Beach 11
Redwood City 11
Ankara 10
Mumbai 10
Orem 10
Portland 10
Shenzhen 10
Tukwila 10
Turin 10
Wuppertal 10
Amsterdam 9
Auburn Hills 9
Totale 15.054
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Nome #
Targeting SARS-CoV-2 by synthetic dual-acting thiol compounds that inhibit Spike/ACE2 interaction and viral protein production 511
Iridium-Catalyzed Direct Synthesis of Tryptamine Derivatives from Indoles: Exploiting N-Protected β-Amino Alcohols as Alkylating Agents 366
Observations concerning the synthesis of tryptamine homologues and branched tryptamine derivatives via the borrowing hydrogen process: synthesis of psilocin, bufotenin, and serotonin 327
Derivatizzazione one-pot di indoli per la sintesi di triptofani, pirroloindoline, bis-indoli & co 325
Synthesis of Boron- and Silicon-Containing Amino Acids through Copper-Catalysed Conjugate Additions to Dehydroalanine Derivatives 321
An improved synthesis of cis-4-phenyl-2-propionamidotetralin (4-P-PDOT): a selective MT2 melatonin receptor antagonist. 298
A simple, modular synthesis of C4-substituted tryptophan derivatives 294
One-Pot Synthesis of Biheterocycles Based on Indole and Azole Scaffolds Using Tryptamines and 1,2-Diaza-1,3-dienes as Building Blocks 290
Synthesis of Tryptamine Derivatives via a Direct, One-Pot Reductive Alkylation of Indoles 287
Palladium(II)-Catalyzed Intramolecular Oxidative C−H/C−H Cross-Coupling Reaction of C3,N-linked Biheterocycles: Rapid Access to Polycyclic Nitrogen Heterocycles 287
A Novel One-Pot Approach of Hexahydropyrrolo[2,3-b]indole Nucleus by a cascade addition/cyclization strategy: Synthesis of (±)-Esermethole 286
Palladium(II)-Catalyzed Cross-Dehydrogenative Coupling (CDC) of N-Phthaloyl Dehydroalanine Esters with Simple Arenes: Stereoselective Synthesis of Z-Dehydrophenylalanine Derivatives 285
Synthesis and Configuration Determination of All Enantiopure Stereoisomers of the Melatonin Receptor Ligand 4-Phenyl-2-propionamidotetralin using an Expedient Optical Resolution of 4-Phenyl-2-tetralone 284
Iron-Catalyzed Direct C3-Benzylation of Indoles with Benzyl Alcohols through Borrowing Hydrogen 281
Direct, Regioselective, and Chemoselective Preparation of Novel Boronated Tryptophans by Friedel–Crafts Alkylation 279
Divergent synthesis of novel 9-deazaxanthine derivatives via late-stage cross-coupling reactions 276
Synthesis of 2-substituted tryptophans via a C3- to C2-alkyl migration 276
Metodo di sintesi di derivati del glutatione [Method for the synthesis of glutathione derivatives] 274
Development of a practical and sustainable strategy for the synthesis of ST1535 by an iron-catalyzed Kumada cross-coupling reaction 265
Synthesis of (−)-Epi-Indolactam V by an Intramolecular Buchwald–Hartwig C–N Coupling Cyclization Reaction 263
2-n-Butyl- 9-methyl-8-(1,2,3)triazol-2-yl-9H-purin-6-ylamine and Analogues as A2A Adenosine Receptor Antagonists. Design, Synthesis, and Pharmacological Characterization 263
An efficient synthesis of the cyclic form of scalemic 2,4-di-epi-polyoxamic acid exploiting the hetero Diels-Alder approach. 259
Potent, Metabolically Stable 2-Alkyl-8-(2H-1,2,3-triazol-2-yl)-9H-adenines as Adenosine A2A Receptor Ligands 259
Synthesis of Tetrahydropyridazine Amino Acid Derivatives by a Formal [4+2| Cycloaddition Reaction of 1,​2-​Diaza-​1,​3-​dienes with Dehydroalanine Esters 255
Tricyclic Alkylamides as Melatonin Receptor Ligands with Antagonist or Inverse Agonist Activity 254
Switchable reactivity of acylated alpha, beta-dehydroamino ester in the Friedel-Crafts alkylation of indoles by changing the Lewis acid. 252
Synthesis of benzo[1,2-d;3,4-d’]diimidazole and 1H-pyrazolo[4,3-b]pyridine as putative A2A receptor antagonists 250
Direct, One-Pot Reductive Alkylation of Anilines with Functionalized Acetals Mediated by Triethylsilane and TFA. Straightforward Route for Unsymmetrically Substituted Ethylenediamine 250
Organocatalyzed coupling of indoles with dehydroalanine esters: synthesis of bis(indolyl)propanoates and indolacrylates 248
Enantioselective Total Synthesis of (−)-Acylfulvene and (−)-Irofulven 244
Synthesis of (±)-cis-Clavicipitic Acid by a Rh(I)-Catalyzed Intramolecular Imine Reaction 240
A Trans-Stereoselective Synthesis of 3-Halo-4-alkyl(aryl)-NH-azetidin-2-ones. 240
Polycyclic Indolines by Acid-Mediated Intramolecular Dearomative Strategy: Reversing Indole Reactivity in the Pictet‒Spengler-Type Reaction 240
Concise and Convergent Enantioselective Total Syntheses of (+)- and (-)-Fumimycin 238
New coumarin-urea based receptor for anions: a selective off-on fluorescence response to fluoride 237
Synthesis and Biological Evaluation of Metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), A Potent Antagonist of the A2AAdenosine Receptor for the Treatment of Parkinson’s Disease 237
5-(2-Ethyl-phenyl)-3-(3-methoxy-phenyl)-1H-[1,2,4]triazole (DL-111-IT ) and related compounds induce morphological apoptotic patterns in cultures of human tumor cell lines 236
An efficient, economical synthesis of hydroxytyrosol and its protected forms via Baeyer–Villiger oxidation 235
C3-Alkylation of indoles and oxindoles by alcohols by means of borrowing hydrogen methodology 232
Facile Synthesis of @-Tide-Strand Peptidomimetics: Improved Assembly in Solution and on Solid Phase 228
Divergent reactions of oxindoles with amino alcohols via the borrowing hydrogen process: oxindole ring opening vs. C3 alkylation 228
Direct B-alkyl Suzuki-Miyaura cross-coupling of 2-halopurines. Practical synthesis os ST1535, a potent adenosine A2A receptor antagonist 227
Brønsted Acid-Catalyzed Bisindolization of α-amido acetals: Synthesis and Anticancer activity of bis(indolyl)ethanamino derivatives 225
Organocatalytic Aza-Friedel-Crafts/Lactonization Domino Reaction of Naphthols and Phenols with 2-Acetamidoacrylate to Naphtho- and Benzofuranones Bearing a Quaternary Center at the C3 Position 225
Organocatalytic synthesis of α-quaternary amino acid derivatives via aza-Friedel–Crafts alkylation of indoles with simple α-amidoacrylates 222
Synthesis, binding and fluorescence studies of a new neutral H-bonding receptor for anions based on 3,5-bis(trifluoromethyl)phenylurea 221
Enantioselective total synthesis of (-)-acylfulvene and (-)-irofulven. 218
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 216
Short and straightforward synthesis of 1,7-dimethyl-1,4,7,10-tetraazacyclododecane 216
New family of polyamine macrocycles containing 2,5-diphenyl[1,3,4]oxadiazole as a signaling unit. Synthesis, acid–base and spectrophotometric properties 215
Conformation by NMR of two tetralin-based receptor ligands 214
Large-Scale Preparation of N-Butanoyl-l-glutathione (C4-GSH) 212
Direct preparation of unsymmetrical difunctionalized cyclen derivatives by an Ugi multicomponent reaction 203
Diastereo- and enantioselective hydrogenation of a challenging enamide derived from 4-phenyl-2-tetralone: an appealing shortcut towards enantiopure cis-2-aminotetraline derivatives 202
Single‐Step Synthesis of Dehydroalanine Derivatives via a Brønsted Acid‐Catalyzed Multicomponent Reaction 202
Stereoselective synthesis of chiral 3,4,5-trisubstituted 1,5-dihydropyrrol-2-ones from azadienes. 200
Neutral urea-based receptors for phosphates: synthesis and spectrophotometric studies 200
Stereochemical aspects of a two-step Staudinger reaction - asymmetric synthesis of chiral azetidine-2-ones. 196
New branched macrocyclic ligand and its side-arm, two urea-based receptors for anions: Synthesis, binding studies and crystal structure 196
Synthesis of (E)-8-(3-Chlorostyryl)caffeine Analogues Leading to 9-Deazaxanthine Derivatives as Dual A2AAntagonists/MAO-B Inhibitors 195
Hydroxytyrosol derivates prevent apoptosis and autophagy. 195
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 193
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 189
Observations in the synthesis of the core of the antitumor illudins via an enyne ring closing metathesis cascade 183
A Versatile Biomimetic Approach to Diindolylmethane Derivatives as Potential Anticancer Agents 182
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 180
Total Synthesis of (-)-Clavicipitic Acid via γ,γ-Dimethylallyltryptophan (DMAT) and Chemoselective C-H Hydroxylation 176
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 174
2-n-butyl-9-methyl-8-(1,2,3)triazol-2yl-9H-purin-6-yl-amine (ST 1535) and analogs as A2a Adenosine receptor antagonists. Design, synthesis and pharmacological characterization 173
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign 173
Concise catalytic asymmetric synthesis of (R)-4-amino Uhle's ketone 169
N-alchil-O-arilcarbammati come inibitori delle idrolasi delle ammidi degli acidi grassi (FAAH): aspetti meccanicistici 168
Oxidated derivatives of triazolylpurines useful as ligands of the adenosine A2A receptor and their use as medicaments 167
Strategies leading to MT2 selective melatonin receptor antagonists 165
DERIVATIVES OF TRIAZOLYL-IMIDAZOPYRIDINE AND OF THE TRIAZOLYLPURINES USEFUL AS LIGANDS OF THE ADENOSINE A2a RECEPTOR AND THEIR USE AS MEDICAMENTS. 160
Quantifying the Interactions that Contribute to beta-Hairpin Folding 159
Derivatives of triazoly-imidazopyridine useful as ligands of the adenosine A2a receptor ant their use as medicaments 157
Design, SAR and Biological Activity of a New Class of FAAH Inhibitors: Cyclohexyl Carbamic Acid Biphenyl-3-yl Esters 147
Protective action of hydroxytyrosol derivates vs apoptosis: apreliminary study. 146
General synthesis of unnatural 4-, 5-, 6-, and 7-bromo-d-tryptophans by means of a regioselective indole alkylation 145
New Receptor For Anions: Signalling Ureido Side-Arms Preorganized On Polyamine Scaffold 141
Novel, Chiral, and Enantiopure C2‐Symmetric Thioureas Promote Asymmetric Protio‐Pictet‐Spengler Reactions by Anion‐Binding Catalysis 134
Dithiol Based on L-Cysteine and Cysteamine as a Disulfide-Reducing Agent 134
Asymmetric Total Synthesis of All Rugulovasine Stereoisomers and Preliminary Evaluation of Their Biological Properties 132
Structure-Activity Relationships of Alkylcarbamic Acid Aryl Esters, as Fatty Acid Amide Hydrolase Inhibitors 130
A Short Synthesis of (−)‐6,7‐Secoagroclavine via Metal‐Free Reductive Coupling 129
Synthesis and Pharmacological Characterization of Potent and Selective Inhibitors of Fatty Acid Amidohydrolase (FAAH) 128
Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamates FAAH inhibitors 124
Design, Synthesis and SAR of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acids Amide Hydrolase Inhibitors 123
Receptors for Anions Based On Signalling Bisureas 122
Asymmetric Alkylation of Cyclic Ketones with Dehydroalanine via H-Bond-Directing Enamine Catalysis: Straightforward Access to Enantiopure Unnatural α-Amino Acids 120
Enantioselective organocatalytic strategies to noncanonical α‐amino acids 119
Mass Spectrometry and Pharmacology Activity: The Case of Carbamic Analogs 117
Esteri bifenil-3-ilici dell'acido cicloesilcarbammico quali inibitori dell'enzima FAAH: sintesi, QSAR e modellistica molecolare 114
The Collisional Behavior of ESI-Generated Protonated Molecules of Some Carbamate Bioisosters and its Relationship with their Biological Activity 111
null 107
Synthesis and Reactivity of Uhle’s Ketone and Its Derivatives 102
Asymmetric Synthesis and Biological Evaluation of Both Enantiomers of 5- and 6-Boronotryptophan as Potential Boron Delivery Agents for Boron Neutron Capture Therapy 98
Redox modulation via a synthetic thiol compound reshapes energy metabolism in endothelial cells and ameliorates angiogenic expression in a co-culture study with activated macrophages 91
Synthesis and Fluorescence Properties of 4-Cyano and 4-Formyl Melatonin as Putative Melatoninergic Ligands 91
Totale 20.973
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Categoria #
all - tutte 73.073
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 73.073
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.601 0 0 0 0 0 155 311 144 345 257 281 108
2021/20221.349 126 186 128 138 20 54 70 77 65 90 64 331
2022/20232.167 179 107 54 231 159 347 11 161 435 144 230 109
2023/2024709 56 45 35 90 34 125 28 44 89 60 17 86
2024/20252.135 87 85 372 143 80 139 346 94 200 170 226 193
2025/20262.904 482 427 586 840 539 30 0 0 0 0 0 0
Totale 21.519