IRIS
PIERSANTI, GIOVANNI
 Distribuzione geografica
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Continente #
NA - Nord America 11.891
EU - Europa 6.994
AS - Asia 3.653
SA - Sud America 350
AF - Africa 53
OC - Oceania 24
Continente sconosciuto - Info sul continente non disponibili 3
Totale 22.968
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Nazione #
US - Stati Uniti d'America 11.747
IT - Italia 2.022
GB - Regno Unito 1.897
CN - Cina 1.690
SG - Singapore 1.029
UA - Ucraina 759
RU - Federazione Russa 564
SE - Svezia 429
DE - Germania 345
FI - Finlandia 337
TR - Turchia 283
BR - Brasile 277
FR - Francia 212
VN - Vietnam 194
IE - Irlanda 158
IN - India 128
CA - Canada 83
KR - Corea 61
NL - Olanda 59
JP - Giappone 56
PL - Polonia 51
HK - Hong Kong 45
MX - Messico 35
BD - Bangladesh 33
BE - Belgio 27
AR - Argentina 25
AU - Australia 21
ES - Italia 20
ZA - Sudafrica 18
CH - Svizzera 17
IQ - Iraq 15
AE - Emirati Arabi Uniti 13
EC - Ecuador 13
ID - Indonesia 13
AT - Austria 11
CL - Cile 10
IR - Iran 10
PK - Pakistan 10
LT - Lituania 9
RO - Romania 9
UZ - Uzbekistan 9
PE - Perù 8
SA - Arabia Saudita 8
VE - Venezuela 8
GR - Grecia 7
KE - Kenya 7
MA - Marocco 7
BG - Bulgaria 6
HR - Croazia 6
KZ - Kazakistan 6
PA - Panama 6
PH - Filippine 6
PT - Portogallo 6
AM - Armenia 5
CR - Costa Rica 5
CZ - Repubblica Ceca 5
EG - Egitto 5
HU - Ungheria 5
AZ - Azerbaigian 4
JO - Giordania 4
KG - Kirghizistan 4
LV - Lettonia 4
TN - Tunisia 4
BY - Bielorussia 3
CY - Cipro 3
DK - Danimarca 3
EU - Europa 3
HN - Honduras 3
IL - Israele 3
MD - Moldavia 3
NO - Norvegia 3
OM - Oman 3
PY - Paraguay 3
RS - Serbia 3
TH - Thailandia 3
TT - Trinidad e Tobago 3
TW - Taiwan 3
AL - Albania 2
AO - Angola 2
BH - Bahrain 2
BO - Bolivia 2
CI - Costa d'Avorio 2
CO - Colombia 2
DO - Repubblica Dominicana 2
EE - Estonia 2
IS - Islanda 2
JM - Giamaica 2
LU - Lussemburgo 2
MY - Malesia 2
NI - Nicaragua 2
SK - Slovacchia (Repubblica Slovacca) 2
SM - San Marino 2
SN - Senegal 2
UY - Uruguay 2
BB - Barbados 1
BW - Botswana 1
CG - Congo 1
GA - Gabon 1
GT - Guatemala 1
KH - Cambogia 1
Totale 22.952
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Città #
Southend 1.629
Fairfield 1.461
Woodbridge 1.392
Ashburn 1.111
Houston 898
Ann Arbor 827
Seattle 607
Jacksonville 592
Chandler 580
Cambridge 564
Urbino 559
Singapore 539
Wilmington 476
San Jose 374
Nanjing 293
Beijing 268
Dallas 266
Izmir 190
Boardman 189
New York 159
Dublin 154
Helsinki 150
Los Angeles 126
Lauterbourg 106
Nanchang 92
Princeton 92
Council Bluffs 83
San Mateo 81
Milan 78
Munich 77
Tianjin 75
Shenyang 72
Ho Chi Minh City 70
Rome 68
Hebei 65
Moscow 64
Changsha 63
Santa Clara 60
San Diego 59
Seongnam 57
London 56
Istanbul 52
Jiaxing 52
Düsseldorf 43
Chicago 42
Buffalo 41
Bremen 40
Hanoi 40
Hong Kong 38
São Paulo 38
Warsaw 38
Kunming 37
San Francisco 36
Shanghai 34
Orem 33
Chennai 32
Velikiy Novgorod 31
Montreal 30
Turku 30
Jinan 29
Toronto 28
Bologna 27
Brussels 26
Denver 26
Frankfurt am Main 26
Stockholm 25
Tokyo 25
Hangzhou 24
Poplar 24
The Dalles 24
Ancona 23
Bellaria-Igea Marina 23
Brooklyn 23
Guangzhou 22
Manchester 19
Augusta 17
Mexico City 16
Nuremberg 16
Paris 16
Amsterdam 15
Atlanta 15
Zhengzhou 15
Dong Ket 14
Ningbo 14
Phoenix 14
Elk Grove Village 13
Johannesburg 13
Ankara 12
Jesi 12
Latina 12
Mumbai 12
Des Moines 11
Lappeenranta 11
Mülheim 11
Norwalk 11
Redondo Beach 11
Redwood City 11
Rio de Janeiro 11
Portland 10
Shenzhen 10
Totale 16.126
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Nome #
Targeting SARS-CoV-2 by synthetic dual-acting thiol compounds that inhibit Spike/ACE2 interaction and viral protein production 545
Derivatizzazione one-pot di indoli per la sintesi di triptofani, pirroloindoline, bis-indoli & co 444
Iridium-Catalyzed Direct Synthesis of Tryptamine Derivatives from Indoles: Exploiting N-Protected β-Amino Alcohols as Alkylating Agents 389
Observations concerning the synthesis of tryptamine homologues and branched tryptamine derivatives via the borrowing hydrogen process: synthesis of psilocin, bufotenin, and serotonin 343
Synthesis of Boron- and Silicon-Containing Amino Acids through Copper-Catalysed Conjugate Additions to Dehydroalanine Derivatives 333
An improved synthesis of cis-4-phenyl-2-propionamidotetralin (4-P-PDOT): a selective MT2 melatonin receptor antagonist. 320
Iron-Catalyzed Direct C3-Benzylation of Indoles with Benzyl Alcohols through Borrowing Hydrogen 311
A simple, modular synthesis of C4-substituted tryptophan derivatives 310
A Novel One-Pot Approach of Hexahydropyrrolo[2,3-b]indole Nucleus by a cascade addition/cyclization strategy: Synthesis of (±)-Esermethole 303
Palladium(II)-Catalyzed Intramolecular Oxidative C−H/C−H Cross-Coupling Reaction of C3,N-linked Biheterocycles: Rapid Access to Polycyclic Nitrogen Heterocycles 303
Metodo di sintesi di derivati del glutatione [Method for the synthesis of glutathione derivatives] 303
One-Pot Synthesis of Biheterocycles Based on Indole and Azole Scaffolds Using Tryptamines and 1,2-Diaza-1,3-dienes as Building Blocks 302
Synthesis and Configuration Determination of All Enantiopure Stereoisomers of the Melatonin Receptor Ligand 4-Phenyl-2-propionamidotetralin using an Expedient Optical Resolution of 4-Phenyl-2-tetralone 299
Synthesis of Tryptamine Derivatives via a Direct, One-Pot Reductive Alkylation of Indoles 296
Palladium(II)-Catalyzed Cross-Dehydrogenative Coupling (CDC) of N-Phthaloyl Dehydroalanine Esters with Simple Arenes: Stereoselective Synthesis of Z-Dehydrophenylalanine Derivatives 295
Direct, Regioselective, and Chemoselective Preparation of Novel Boronated Tryptophans by Friedel–Crafts Alkylation 292
Divergent synthesis of novel 9-deazaxanthine derivatives via late-stage cross-coupling reactions 288
Synthesis of 2-substituted tryptophans via a C3- to C2-alkyl migration 285
Development of a practical and sustainable strategy for the synthesis of ST1535 by an iron-catalyzed Kumada cross-coupling reaction 278
Synthesis of (−)-Epi-Indolactam V by an Intramolecular Buchwald–Hartwig C–N Coupling Cyclization Reaction 272
2-n-Butyl- 9-methyl-8-(1,2,3)triazol-2-yl-9H-purin-6-ylamine and Analogues as A2A Adenosine Receptor Antagonists. Design, Synthesis, and Pharmacological Characterization 272
Tricyclic Alkylamides as Melatonin Receptor Ligands with Antagonist or Inverse Agonist Activity 270
Potent, Metabolically Stable 2-Alkyl-8-(2H-1,2,3-triazol-2-yl)-9H-adenines as Adenosine A2A Receptor Ligands 268
Concise and Convergent Enantioselective Total Syntheses of (+)- and (-)-Fumimycin 267
An efficient synthesis of the cyclic form of scalemic 2,4-di-epi-polyoxamic acid exploiting the hetero Diels-Alder approach. 265
Direct, One-Pot Reductive Alkylation of Anilines with Functionalized Acetals Mediated by Triethylsilane and TFA. Straightforward Route for Unsymmetrically Substituted Ethylenediamine 264
Synthesis of Tetrahydropyridazine Amino Acid Derivatives by a Formal [4+2| Cycloaddition Reaction of 1,​2-​Diaza-​1,​3-​dienes with Dehydroalanine Esters 262
Synthesis of benzo[1,2-d;3,4-d’]diimidazole and 1H-pyrazolo[4,3-b]pyridine as putative A2A receptor antagonists 260
Switchable reactivity of acylated alpha, beta-dehydroamino ester in the Friedel-Crafts alkylation of indoles by changing the Lewis acid. 260
New coumarin-urea based receptor for anions: a selective off-on fluorescence response to fluoride 258
Enantioselective Total Synthesis of (−)-Acylfulvene and (−)-Irofulven 255
An efficient, economical synthesis of hydroxytyrosol and its protected forms via Baeyer–Villiger oxidation 255
5-(2-Ethyl-phenyl)-3-(3-methoxy-phenyl)-1H-[1,2,4]triazole (DL-111-IT ) and related compounds induce morphological apoptotic patterns in cultures of human tumor cell lines 254
Organocatalyzed coupling of indoles with dehydroalanine esters: synthesis of bis(indolyl)propanoates and indolacrylates 254
A Trans-Stereoselective Synthesis of 3-Halo-4-alkyl(aryl)-NH-azetidin-2-ones. 252
Synthesis and Biological Evaluation of Metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), A Potent Antagonist of the A2AAdenosine Receptor for the Treatment of Parkinson’s Disease 252
Polycyclic Indolines by Acid-Mediated Intramolecular Dearomative Strategy: Reversing Indole Reactivity in the Pictet‒Spengler-Type Reaction 251
Synthesis of (±)-cis-Clavicipitic Acid by a Rh(I)-Catalyzed Intramolecular Imine Reaction 247
C3-Alkylation of indoles and oxindoles by alcohols by means of borrowing hydrogen methodology 243
Divergent reactions of oxindoles with amino alcohols via the borrowing hydrogen process: oxindole ring opening vs. C3 alkylation 239
Direct B-alkyl Suzuki-Miyaura cross-coupling of 2-halopurines. Practical synthesis os ST1535, a potent adenosine A2A receptor antagonist 237
Brønsted Acid-Catalyzed Bisindolization of α-amido acetals: Synthesis and Anticancer activity of bis(indolyl)ethanamino derivatives 237
Synthesis, binding and fluorescence studies of a new neutral H-bonding receptor for anions based on 3,5-bis(trifluoromethyl)phenylurea 236
Organocatalytic Aza-Friedel-Crafts/Lactonization Domino Reaction of Naphthols and Phenols with 2-Acetamidoacrylate to Naphtho- and Benzofuranones Bearing a Quaternary Center at the C3 Position 235
Facile Synthesis of @-Tide-Strand Peptidomimetics: Improved Assembly in Solution and on Solid Phase 234
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 232
Neutral urea-based receptors for phosphates: synthesis and spectrophotometric studies 232
Organocatalytic synthesis of α-quaternary amino acid derivatives via aza-Friedel–Crafts alkylation of indoles with simple α-amidoacrylates 230
New family of polyamine macrocycles containing 2,5-diphenyl[1,3,4]oxadiazole as a signaling unit. Synthesis, acid–base and spectrophotometric properties 228
Short and straightforward synthesis of 1,7-dimethyl-1,4,7,10-tetraazacyclododecane 227
Enantioselective total synthesis of (-)-acylfulvene and (-)-irofulven. 224
Large-Scale Preparation of N-Butanoyl-l-glutathione (C4-GSH) 224
Diastereo- and enantioselective hydrogenation of a challenging enamide derived from 4-phenyl-2-tetralone: an appealing shortcut towards enantiopure cis-2-aminotetraline derivatives 223
Conformation by NMR of two tetralin-based receptor ligands 221
Single‐Step Synthesis of Dehydroalanine Derivatives via a Brønsted Acid‐Catalyzed Multicomponent Reaction 216
Hydroxytyrosol derivates prevent apoptosis and autophagy. 213
Direct preparation of unsymmetrical difunctionalized cyclen derivatives by an Ugi multicomponent reaction 211
Stereoselective synthesis of chiral 3,4,5-trisubstituted 1,5-dihydropyrrol-2-ones from azadienes. 208
New branched macrocyclic ligand and its side-arm, two urea-based receptors for anions: Synthesis, binding studies and crystal structure 207
Synthesis of (E)-8-(3-Chlorostyryl)caffeine Analogues Leading to 9-Deazaxanthine Derivatives as Dual A2AAntagonists/MAO-B Inhibitors 205
Concise catalytic asymmetric synthesis of (R)-4-amino Uhle's ketone 205
A Versatile Biomimetic Approach to Diindolylmethane Derivatives as Potential Anticancer Agents 204
Stereochemical aspects of a two-step Staudinger reaction - asymmetric synthesis of chiral azetidine-2-ones. 203
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 203
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 195
2-n-butyl-9-methyl-8-(1,2,3)triazol-2yl-9H-purin-6-yl-amine (ST 1535) and analogs as A2a Adenosine receptor antagonists. Design, synthesis and pharmacological characterization 188
Observations in the synthesis of the core of the antitumor illudins via an enyne ring closing metathesis cascade 187
Total Synthesis of (-)-Clavicipitic Acid via γ,γ-Dimethylallyltryptophan (DMAT) and Chemoselective C-H Hydroxylation 187
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 185
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign 185
Strategies leading to MT2 selective melatonin receptor antagonists 181
Oxidated derivatives of triazolylpurines useful as ligands of the adenosine A2A receptor and their use as medicaments 180
DERIVATIVES OF TRIAZOLYL-IMIDAZOPYRIDINE AND OF THE TRIAZOLYLPURINES USEFUL AS LIGANDS OF THE ADENOSINE A2a RECEPTOR AND THEIR USE AS MEDICAMENTS. 178
N-alchil-O-arilcarbammati come inibitori delle idrolasi delle ammidi degli acidi grassi (FAAH): aspetti meccanicistici 178
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 177
Derivatives of triazoly-imidazopyridine useful as ligands of the adenosine A2a receptor ant their use as medicaments 169
Quantifying the Interactions that Contribute to beta-Hairpin Folding 165
General synthesis of unnatural 4-, 5-, 6-, and 7-bromo-d-tryptophans by means of a regioselective indole alkylation 163
Protective action of hydroxytyrosol derivates vs apoptosis: apreliminary study. 162
Dithiol Based on L-Cysteine and Cysteamine as a Disulfide-Reducing Agent 160
Asymmetric Total Synthesis of All Rugulovasine Stereoisomers and Preliminary Evaluation of Their Biological Properties 156
New Receptor For Anions: Signalling Ureido Side-Arms Preorganized On Polyamine Scaffold 156
Design, SAR and Biological Activity of a New Class of FAAH Inhibitors: Cyclohexyl Carbamic Acid Biphenyl-3-yl Esters 154
A Short Synthesis of (−)‐6,7‐Secoagroclavine via Metal‐Free Reductive Coupling 151
Novel, Chiral, and Enantiopure C2‐Symmetric Thioureas Promote Asymmetric Protio‐Pictet‐Spengler Reactions by Anion‐Binding Catalysis 150
Enantioselective organocatalytic strategies to noncanonical α‐amino acids 149
Asymmetric Alkylation of Cyclic Ketones with Dehydroalanine via H-Bond-Directing Enamine Catalysis: Straightforward Access to Enantiopure Unnatural α-Amino Acids 142
Structure-Activity Relationships of Alkylcarbamic Acid Aryl Esters, as Fatty Acid Amide Hydrolase Inhibitors 142
Receptors for Anions Based On Signalling Bisureas 138
Design, Synthesis and SAR of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acids Amide Hydrolase Inhibitors 134
Synthesis and Pharmacological Characterization of Potent and Selective Inhibitors of Fatty Acid Amidohydrolase (FAAH) 134
Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamates FAAH inhibitors 130
Asymmetric Synthesis and Biological Evaluation of Both Enantiomers of 5- and 6-Boronotryptophan as Potential Boron Delivery Agents for Boron Neutron Capture Therapy 129
Redox modulation via a synthetic thiol compound reshapes energy metabolism in endothelial cells and ameliorates angiogenic expression in a co-culture study with activated macrophages 129
Mass Spectrometry and Pharmacology Activity: The Case of Carbamic Analogs 127
Esteri bifenil-3-ilici dell'acido cicloesilcarbammico quali inibitori dell'enzima FAAH: sintesi, QSAR e modellistica molecolare 124
The Collisional Behavior of ESI-Generated Protonated Molecules of Some Carbamate Bioisosters and its Relationship with their Biological Activity 118
Synthesis and Fluorescence Properties of 4-Cyano and 4-Formyl Melatonin as Putative Melatoninergic Ligands 114
Small molecule-mediated inhibition of the oxidoreductase ERO1A restrains aggressive breast cancer by impairing VEGF and PD-L1 in the tumor microenvironment 112
Synthesis and Reactivity of Uhle’s Ketone and Its Derivatives 110
Totale 22.493
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Categoria #
all - tutte 76.064
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 76.064
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021646 0 0 0 0 0 0 0 0 0 257 281 108
2021/20221.349 126 186 128 138 20 54 70 77 65 90 64 331
2022/20232.167 179 107 54 231 159 347 11 161 435 144 230 109
2023/2024708 56 45 35 89 34 125 28 44 89 60 17 86
2024/20252.129 87 85 369 143 80 138 346 93 199 170 226 193
2025/20264.676 482 427 586 839 539 331 546 204 350 372 0 0
Totale 23.284