IRIS
PIERSANTI, GIOVANNI
 Distribuzione geografica
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Continente #
NA - Nord America 12.229
EU - Europa 7.050
AS - Asia 3.761
SA - Sud America 350
AF - Africa 54
OC - Oceania 24
Continente sconosciuto - Info sul continente non disponibili 3
Totale 23.471
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Nazione #
US - Stati Uniti d'America 12.069
IT - Italia 2.070
GB - Regno Unito 1.898
CN - Cina 1.726
SG - Singapore 1.071
UA - Ucraina 759
RU - Federazione Russa 564
SE - Svezia 429
DE - Germania 346
FI - Finlandia 337
TR - Turchia 283
BR - Brasile 277
FR - Francia 213
VN - Vietnam 194
IE - Irlanda 158
IN - India 128
CA - Canada 91
KR - Corea 63
NL - Olanda 62
BD - Bangladesh 58
JP - Giappone 56
PL - Polonia 52
HK - Hong Kong 47
MX - Messico 38
BE - Belgio 27
AR - Argentina 25
AU - Australia 21
ES - Italia 20
ZA - Sudafrica 18
CH - Svizzera 17
IQ - Iraq 15
AE - Emirati Arabi Uniti 13
EC - Ecuador 13
ID - Indonesia 13
AT - Austria 11
CL - Cile 10
IR - Iran 10
PK - Pakistan 10
LT - Lituania 9
RO - Romania 9
UZ - Uzbekistan 9
PE - Perù 8
SA - Arabia Saudita 8
VE - Venezuela 8
BG - Bulgaria 7
GR - Grecia 7
KE - Kenya 7
MA - Marocco 7
CR - Costa Rica 6
EG - Egitto 6
HR - Croazia 6
KZ - Kazakistan 6
PA - Panama 6
PH - Filippine 6
PT - Portogallo 6
AM - Armenia 5
CZ - Repubblica Ceca 5
HU - Ungheria 5
JM - Giamaica 5
AZ - Azerbaigian 4
JO - Giordania 4
KG - Kirghizistan 4
LV - Lettonia 4
TN - Tunisia 4
BH - Bahrain 3
BY - Bielorussia 3
CY - Cipro 3
DK - Danimarca 3
EU - Europa 3
HN - Honduras 3
IL - Israele 3
MD - Moldavia 3
NO - Norvegia 3
OM - Oman 3
PY - Paraguay 3
RS - Serbia 3
TH - Thailandia 3
TT - Trinidad e Tobago 3
TW - Taiwan 3
AL - Albania 2
AO - Angola 2
BO - Bolivia 2
CI - Costa d'Avorio 2
CO - Colombia 2
DO - Repubblica Dominicana 2
EE - Estonia 2
IS - Islanda 2
LU - Lussemburgo 2
MY - Malesia 2
NI - Nicaragua 2
PR - Porto Rico 2
SK - Slovacchia (Repubblica Slovacca) 2
SM - San Marino 2
SN - Senegal 2
UY - Uruguay 2
BB - Barbados 1
BW - Botswana 1
CG - Congo 1
GA - Gabon 1
GT - Guatemala 1
Totale 23.455
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Città #
Southend 1.629
Fairfield 1.461
Woodbridge 1.393
Ashburn 1.120
Houston 901
Ann Arbor 827
Seattle 608
Jacksonville 592
Chandler 580
Cambridge 564
Urbino 559
Singapore 546
Wilmington 476
San Jose 440
Nanjing 293
Beijing 281
Dallas 270
Boardman 218
Izmir 190
New York 176
Dublin 154
Helsinki 150
Council Bluffs 136
Los Angeles 134
Lauterbourg 106
Nanchang 92
Princeton 92
Milan 82
San Mateo 81
Munich 77
Tianjin 75
Rome 73
Shenyang 72
Ho Chi Minh City 70
Santa Clara 70
Hebei 65
Moscow 64
Changsha 63
San Diego 59
London 57
Seongnam 57
Istanbul 52
Jiaxing 52
Chicago 44
Buffalo 43
Düsseldorf 43
Bremen 40
Hanoi 40
Hong Kong 40
São Paulo 38
Warsaw 38
Kunming 37
San Francisco 37
Orem 36
Shanghai 34
Chennai 32
Montreal 32
Toronto 31
Velikiy Novgorod 31
Turku 30
Jinan 29
Bologna 27
Denver 27
Brooklyn 26
Brussels 26
Frankfurt am Main 26
Hangzhou 26
Stockholm 25
The Dalles 25
Tokyo 25
Ancona 24
Poplar 24
Bellaria-Igea Marina 23
Guangzhou 22
Columbus 19
Manchester 19
Mexico City 19
Augusta 17
Nuremberg 16
Paris 16
Amsterdam 15
Atlanta 15
Zhengzhou 15
Dong Ket 14
Ningbo 14
Phoenix 14
Elk Grove Village 13
Johannesburg 13
Ankara 12
Jesi 12
Latina 12
Mumbai 12
Des Moines 11
Lappeenranta 11
Mülheim 11
Naples 11
Norwalk 11
Redondo Beach 11
Redwood City 11
Rio de Janeiro 11
Totale 16.393
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Nome #
Targeting SARS-CoV-2 by synthetic dual-acting thiol compounds that inhibit Spike/ACE2 interaction and viral protein production 548
Derivatizzazione one-pot di indoli per la sintesi di triptofani, pirroloindoline, bis-indoli & co 464
Iridium-Catalyzed Direct Synthesis of Tryptamine Derivatives from Indoles: Exploiting N-Protected β-Amino Alcohols as Alkylating Agents 391
Observations concerning the synthesis of tryptamine homologues and branched tryptamine derivatives via the borrowing hydrogen process: synthesis of psilocin, bufotenin, and serotonin 346
Synthesis of Boron- and Silicon-Containing Amino Acids through Copper-Catalysed Conjugate Additions to Dehydroalanine Derivatives 338
An improved synthesis of cis-4-phenyl-2-propionamidotetralin (4-P-PDOT): a selective MT2 melatonin receptor antagonist. 327
Metodo di sintesi di derivati del glutatione [Method for the synthesis of glutathione derivatives] 327
A simple, modular synthesis of C4-substituted tryptophan derivatives 316
Iron-Catalyzed Direct C3-Benzylation of Indoles with Benzyl Alcohols through Borrowing Hydrogen 311
A Novel One-Pot Approach of Hexahydropyrrolo[2,3-b]indole Nucleus by a cascade addition/cyclization strategy: Synthesis of (±)-Esermethole 309
One-Pot Synthesis of Biheterocycles Based on Indole and Azole Scaffolds Using Tryptamines and 1,2-Diaza-1,3-dienes as Building Blocks 308
Palladium(II)-Catalyzed Intramolecular Oxidative C−H/C−H Cross-Coupling Reaction of C3,N-linked Biheterocycles: Rapid Access to Polycyclic Nitrogen Heterocycles 307
Synthesis and Configuration Determination of All Enantiopure Stereoisomers of the Melatonin Receptor Ligand 4-Phenyl-2-propionamidotetralin using an Expedient Optical Resolution of 4-Phenyl-2-tetralone 303
Synthesis of Tryptamine Derivatives via a Direct, One-Pot Reductive Alkylation of Indoles 300
Palladium(II)-Catalyzed Cross-Dehydrogenative Coupling (CDC) of N-Phthaloyl Dehydroalanine Esters with Simple Arenes: Stereoselective Synthesis of Z-Dehydrophenylalanine Derivatives 297
Direct, Regioselective, and Chemoselective Preparation of Novel Boronated Tryptophans by Friedel–Crafts Alkylation 295
Divergent synthesis of novel 9-deazaxanthine derivatives via late-stage cross-coupling reactions 290
Synthesis of 2-substituted tryptophans via a C3- to C2-alkyl migration 286
Development of a practical and sustainable strategy for the synthesis of ST1535 by an iron-catalyzed Kumada cross-coupling reaction 280
Tricyclic Alkylamides as Melatonin Receptor Ligands with Antagonist or Inverse Agonist Activity 277
Potent, Metabolically Stable 2-Alkyl-8-(2H-1,2,3-triazol-2-yl)-9H-adenines as Adenosine A2A Receptor Ligands 277
2-n-Butyl- 9-methyl-8-(1,2,3)triazol-2-yl-9H-purin-6-ylamine and Analogues as A2A Adenosine Receptor Antagonists. Design, Synthesis, and Pharmacological Characterization 276
Synthesis of (−)-Epi-Indolactam V by an Intramolecular Buchwald–Hartwig C–N Coupling Cyclization Reaction 274
Concise and Convergent Enantioselective Total Syntheses of (+)- and (-)-Fumimycin 269
Direct, One-Pot Reductive Alkylation of Anilines with Functionalized Acetals Mediated by Triethylsilane and TFA. Straightforward Route for Unsymmetrically Substituted Ethylenediamine 267
An efficient synthesis of the cyclic form of scalemic 2,4-di-epi-polyoxamic acid exploiting the hetero Diels-Alder approach. 267
Synthesis of benzo[1,2-d;3,4-d’]diimidazole and 1H-pyrazolo[4,3-b]pyridine as putative A2A receptor antagonists 266
An efficient, economical synthesis of hydroxytyrosol and its protected forms via Baeyer–Villiger oxidation 263
Synthesis of Tetrahydropyridazine Amino Acid Derivatives by a Formal [4+2| Cycloaddition Reaction of 1,​2-​Diaza-​1,​3-​dienes with Dehydroalanine Esters 262
New coumarin-urea based receptor for anions: a selective off-on fluorescence response to fluoride 261
Switchable reactivity of acylated alpha, beta-dehydroamino ester in the Friedel-Crafts alkylation of indoles by changing the Lewis acid. 260
Enantioselective Total Synthesis of (−)-Acylfulvene and (−)-Irofulven 258
A Trans-Stereoselective Synthesis of 3-Halo-4-alkyl(aryl)-NH-azetidin-2-ones. 257
Organocatalyzed coupling of indoles with dehydroalanine esters: synthesis of bis(indolyl)propanoates and indolacrylates 256
Synthesis and Biological Evaluation of Metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), A Potent Antagonist of the A2AAdenosine Receptor for the Treatment of Parkinson’s Disease 256
Polycyclic Indolines by Acid-Mediated Intramolecular Dearomative Strategy: Reversing Indole Reactivity in the Pictet‒Spengler-Type Reaction 255
5-(2-Ethyl-phenyl)-3-(3-methoxy-phenyl)-1H-[1,2,4]triazole (DL-111-IT ) and related compounds induce morphological apoptotic patterns in cultures of human tumor cell lines 254
Synthesis of (±)-cis-Clavicipitic Acid by a Rh(I)-Catalyzed Intramolecular Imine Reaction 247
C3-Alkylation of indoles and oxindoles by alcohols by means of borrowing hydrogen methodology 247
Divergent reactions of oxindoles with amino alcohols via the borrowing hydrogen process: oxindole ring opening vs. C3 alkylation 243
Brønsted Acid-Catalyzed Bisindolization of α-amido acetals: Synthesis and Anticancer activity of bis(indolyl)ethanamino derivatives 239
Synthesis, binding and fluorescence studies of a new neutral H-bonding receptor for anions based on 3,5-bis(trifluoromethyl)phenylurea 238
Direct B-alkyl Suzuki-Miyaura cross-coupling of 2-halopurines. Practical synthesis os ST1535, a potent adenosine A2A receptor antagonist 238
Organocatalytic Aza-Friedel-Crafts/Lactonization Domino Reaction of Naphthols and Phenols with 2-Acetamidoacrylate to Naphtho- and Benzofuranones Bearing a Quaternary Center at the C3 Position 238
Facile Synthesis of @-Tide-Strand Peptidomimetics: Improved Assembly in Solution and on Solid Phase 236
Neutral urea-based receptors for phosphates: synthesis and spectrophotometric studies 236
Cyclohexylcarbamic Acid 3’-or 4’-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis Quantitative Structure–Activity Relationships, and Molecular Modeling Studies 235
Short and straightforward synthesis of 1,7-dimethyl-1,4,7,10-tetraazacyclododecane 234
Organocatalytic synthesis of α-quaternary amino acid derivatives via aza-Friedel–Crafts alkylation of indoles with simple α-amidoacrylates 233
New family of polyamine macrocycles containing 2,5-diphenyl[1,3,4]oxadiazole as a signaling unit. Synthesis, acid–base and spectrophotometric properties 230
Large-Scale Preparation of N-Butanoyl-l-glutathione (C4-GSH) 229
Enantioselective total synthesis of (-)-acylfulvene and (-)-irofulven. 227
Conformation by NMR of two tetralin-based receptor ligands 226
Diastereo- and enantioselective hydrogenation of a challenging enamide derived from 4-phenyl-2-tetralone: an appealing shortcut towards enantiopure cis-2-aminotetraline derivatives 225
Hydroxytyrosol derivates prevent apoptosis and autophagy. 222
Single‐Step Synthesis of Dehydroalanine Derivatives via a Brønsted Acid‐Catalyzed Multicomponent Reaction 221
Direct preparation of unsymmetrical difunctionalized cyclen derivatives by an Ugi multicomponent reaction 217
Stereoselective synthesis of chiral 3,4,5-trisubstituted 1,5-dihydropyrrol-2-ones from azadienes. 215
A Versatile Biomimetic Approach to Diindolylmethane Derivatives as Potential Anticancer Agents 213
Synthesis and Quantitative Structure–Activity Relationship of Fatty Acid Amide Hydrolase Inhibitors: Modulation at the N-Portion of Biphenyl-3-yl Alkylcarbamates 211
Concise catalytic asymmetric synthesis of (R)-4-amino Uhle's ketone 211
Synthesis of (E)-8-(3-Chlorostyryl)caffeine Analogues Leading to 9-Deazaxanthine Derivatives as Dual A2AAntagonists/MAO-B Inhibitors 210
New branched macrocyclic ligand and its side-arm, two urea-based receptors for anions: Synthesis, binding studies and crystal structure 209
Stereochemical aspects of a two-step Staudinger reaction - asymmetric synthesis of chiral azetidine-2-ones. 204
Design, Synthesis and Structure–Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors 196
2-n-butyl-9-methyl-8-(1,2,3)triazol-2yl-9H-purin-6-yl-amine (ST 1535) and analogs as A2a Adenosine receptor antagonists. Design, synthesis and pharmacological characterization 190
Observations in the synthesis of the core of the antitumor illudins via an enyne ring closing metathesis cascade 188
Total Synthesis of (-)-Clavicipitic Acid via γ,γ-Dimethylallyltryptophan (DMAT) and Chemoselective C-H Hydroxylation 188
Oxidated derivatives of triazolylpurines useful as ligands of the adenosine A2A receptor and their use as medicaments 185
Synthesis and Structure–Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring 185
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign 185
Strategies leading to MT2 selective melatonin receptor antagonists 184
DERIVATIVES OF TRIAZOLYL-IMIDAZOPYRIDINE AND OF THE TRIAZOLYLPURINES USEFUL AS LIGANDS OF THE ADENOSINE A2a RECEPTOR AND THEIR USE AS MEDICAMENTS. 180
N-alchil-O-arilcarbammati come inibitori delle idrolasi delle ammidi degli acidi grassi (FAAH): aspetti meccanicistici 179
The collisional behavior of ESI-generated protonated molecules of some carbamate FAAH inhibitors isosteres and its relationships with biological activity 179
Protective action of hydroxytyrosol derivates vs apoptosis: apreliminary study. 173
Derivatives of triazoly-imidazopyridine useful as ligands of the adenosine A2a receptor ant their use as medicaments 172
Quantifying the Interactions that Contribute to beta-Hairpin Folding 169
General synthesis of unnatural 4-, 5-, 6-, and 7-bromo-d-tryptophans by means of a regioselective indole alkylation 168
Dithiol Based on L-Cysteine and Cysteamine as a Disulfide-Reducing Agent 163
Asymmetric Total Synthesis of All Rugulovasine Stereoisomers and Preliminary Evaluation of Their Biological Properties 161
Design, SAR and Biological Activity of a New Class of FAAH Inhibitors: Cyclohexyl Carbamic Acid Biphenyl-3-yl Esters 157
New Receptor For Anions: Signalling Ureido Side-Arms Preorganized On Polyamine Scaffold 157
A Short Synthesis of (−)‐6,7‐Secoagroclavine via Metal‐Free Reductive Coupling 156
Novel, Chiral, and Enantiopure C2‐Symmetric Thioureas Promote Asymmetric Protio‐Pictet‐Spengler Reactions by Anion‐Binding Catalysis 155
Enantioselective organocatalytic strategies to noncanonical α‐amino acids 153
A New Bis‐Urea Based Cage Receptor for Anions: Synthesis, Solid State Structures and Binding Studies 148
Asymmetric Alkylation of Cyclic Ketones with Dehydroalanine via H-Bond-Directing Enamine Catalysis: Straightforward Access to Enantiopure Unnatural α-Amino Acids 145
Structure-Activity Relationships of Alkylcarbamic Acid Aryl Esters, as Fatty Acid Amide Hydrolase Inhibitors 145
Design, Synthesis and SAR of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acids Amide Hydrolase Inhibitors 145
Receptors for Anions Based On Signalling Bisureas 141
Synthesis and Pharmacological Characterization of Potent and Selective Inhibitors of Fatty Acid Amidohydrolase (FAAH) 138
Asymmetric Synthesis and Biological Evaluation of Both Enantiomers of 5- and 6-Boronotryptophan as Potential Boron Delivery Agents for Boron Neutron Capture Therapy 133
Redox modulation via a synthetic thiol compound reshapes energy metabolism in endothelial cells and ameliorates angiogenic expression in a co-culture study with activated macrophages 132
Correlation between energetics of collisionally activated decompositions, interaction energy and biological potency of carbamates FAAH inhibitors 131
Mass Spectrometry and Pharmacology Activity: The Case of Carbamic Analogs 129
Esteri bifenil-3-ilici dell'acido cicloesilcarbammico quali inibitori dell'enzima FAAH: sintesi, QSAR e modellistica molecolare 126
Small molecule-mediated inhibition of the oxidoreductase ERO1A restrains aggressive breast cancer by impairing VEGF and PD-L1 in the tumor microenvironment 125
Synthesis and Fluorescence Properties of 4-Cyano and 4-Formyl Melatonin as Putative Melatoninergic Ligands 122
The Collisional Behavior of ESI-Generated Protonated Molecules of Some Carbamate Bioisosters and its Relationship with their Biological Activity 120
Totale 22.935
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Categoria #
all - tutte 79.202
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 79.202
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021108 0 0 0 0 0 0 0 0 0 0 0 108
2021/20221.349 126 186 128 138 20 54 70 77 65 90 64 331
2022/20232.167 179 107 54 231 159 347 11 161 435 144 230 109
2023/2024708 56 45 35 89 34 125 28 44 89 60 17 86
2024/20252.129 87 85 369 143 80 138 346 93 199 170 226 193
2025/20265.181 482 427 586 839 539 331 546 204 350 484 277 116
Totale 23.789